Klf16 (Kruppel-like transcription factor 16)

Gene: Klf16 (Kruppel-like transcription factor 16) Mus musculus

Analyze

Symbol:

Klf16

Name:

Kruppel-like transcription factor 16

RGD ID:

1314309

MGI Page

MGI

Description:

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of transcription by RNA polymerase II. Acts upstream of or within dopamine receptor signaling pathway and regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including brain; embryo mesenchyme; genitourinary system; gut; and retina. Orthologous to human KLF16 (KLF transcription factor 16).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AI843742; basic transcription element-binding protein 4; BTE-binding protein 4; BTEB4; dopamine receptor regulating factor; dopamine receptor-regulating factor; DR; DRRF; Krueppel-like factor 16; Kruppel-like factor 16; transcription factor BTEB4

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	KLF16 (KLF transcription factor 16)	HGNC	EggNOG, Ensembl, HGNC, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Klf16 (KLF transcription factor 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Klf16 (KLF transcription factor 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	KLF16 (KLF transcription factor 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	KLF16 (KLF transcription factor 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Klf16 (KLF transcription factor 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	KLF16 (KLF transcription factor 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	KLF16 (KLF transcription factor 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Klf16 (KLF transcription factor 16)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Klf16 (KLF transcription factor 16)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	KLF16 (KLF transcription factor 16)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	zgc:153115	Alliance	DIOPT (Ensembl Compara\|OMA)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	80,402,955 - 80,413,130 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	80,402,958 - 80,413,155 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	80,567,121 - 80,577,296 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	80,567,124 - 80,577,321 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	80,029,866 - 80,040,041 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	79,970,264 - 79,980,423 (-)	NCBI		MGSCv36	mm8
Celera	10	81,584,920 - 81,595,095 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cyclic hematopoiesis (ISO)

genetic disease (ISO)

Neurodevelopmental Disorders (ISO)

progressive myoclonus epilepsy 9 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (EXP)

1,2-dimethylhydrazine (EXP)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,4-methylenedioxymethamphetamine (EXP)

6-propyl-2-thiouracil (ISO)

acrolein (ISO)

acrylamide (ISO)

alpha-pinene (ISO)

amiodarone (ISO)

amitrole (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

avobenzone (ISO)

benzo[a]pyrene (EXP,ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP,ISO)

caffeine (ISO)

chlorpyrifos (EXP)

cisplatin (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (ISO)

diazinon (ISO)

dicrotophos (ISO)

folic acid (EXP)

FR900359 (ISO)

gentamycin (ISO)

ivermectin (ISO)

methapyrilene (ISO)

methimazole (ISO)

N-methyl-4-phenylpyridinium (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (EXP)

perfluorooctane-1-sulfonic acid (EXP)

resveratrol (ISO)

simvastatin (EXP)

sulfadimethoxine (ISO)

sunitinib (ISO)

tetrachloromethane (EXP)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

dopamine receptor signaling pathway (IDA)

negative regulation of transcription by RNA polymerase II (IDA)

regulation of transcription by RNA polymerase II (IBA,IDA)

Cellular Component

nucleus (IEA)

Molecular Function

DNA binding (IDA,ISS)

DNA-binding transcription factor activity (IDA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

DNA-binding transcription repressor activity, RNA polymerase II-specific (IDA)

metal ion binding (IEA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA,IDA)

sequence-specific double-stranded DNA binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal embryo size (IEA)

decreased circulating glucose level (IEA)

decreased circulating total protein level (IEA)

decreased leukocyte cell number (IEA)

increased circulating phosphate level (IEA)

increased mean corpuscular hemoglobin (IEA)

increased mean corpuscular volume (IEA)

preweaning lethality, incomplete penetrance (IEA)

prolonged QRS complex duration (IEA)

prolonged QT interval (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse brain organization revealed through direct genome-scale TF expression analysis.	Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11217851	PMID:11390978	PMID:11744383	PMID:12466851	PMID:12477932	PMID:12520002	PMID:12568728	PMID:14610273
PMID:15782199	PMID:15820306	PMID:16141072	PMID:16141073	PMID:16602821	PMID:18287559	PMID:18472212	PMID:18799693	PMID:20059953	PMID:20412781	PMID:21267068	PMID:21873635
PMID:27402841	PMID:27611969	PMID:27743478	PMID:32098917	PMID:34823421

Genomics

Comparative Map Data

Klf16
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	80,402,955 - 80,413,130 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	80,402,958 - 80,413,155 (-)	Ensembl		GRCm39 Ensembl
GRCm38	10	80,567,121 - 80,577,296 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	80,567,124 - 80,577,321 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	10	80,029,866 - 80,040,041 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	10	79,970,264 - 79,980,423 (-)	NCBI		MGSCv36	mm8
Celera	10	81,584,920 - 81,595,095 (-)	NCBI		Celera
Cytogenetic Map	10	C1	NCBI
cM Map	10	39.72	NCBI

KLF16
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	1,852,399 - 1,876,536 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	1,852,399 - 1,863,579 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	1,852,398 - 1,863,578 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	1,803,398 - 1,814,564 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	1,803,398 - 1,814,496	NCBI
Celera	19	1,786,480 - 1,797,646 (-)	NCBI		Celera
Cytogenetic Map	19	p13.3	NCBI
HuRef	19	1,624,071 - 1,636,584 (-)	NCBI		HuRef
CHM1_1	19	1,852,027 - 1,863,203 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	19	1,823,714 - 1,847,856 (-)	NCBI		T2T-CHM13v2.0

Klf16
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	9,789,185 - 9,799,004 (+)	NCBI		GRCr8
mRatBN7.2	7	9,138,503 - 9,148,322 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	9,138,503 - 9,148,317 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	7	12,016,798 - 12,026,599 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	13,892,312 - 13,902,113 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	11,758,326 - 11,768,126 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	12,006,710 - 12,016,529 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	12,006,710 - 12,016,524 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	7	12,174,235 - 12,184,054 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	7	10,638,982 - 10,658,693 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	7	10,653,978 - 10,656,966 (+)	NCBI
Celera	7	7,320,617 - 7,330,425 (+)	NCBI		Celera
Cytogenetic Map	7	q11	NCBI

Klf16
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955495	6,178,565 - 6,189,469 (+)	NCBI	ChiLan1.0	ChiLan1.0

KLF16
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	6,223,021 - 6,234,313 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	5,453,986 - 5,465,287 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	850,840 - 862,130 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	1,832,876 - 1,858,726 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

KLF16
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	57,102,968 - 57,110,795 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	56,894,945 - 56,904,879 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	57,833,113 - 57,843,031 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	20	56,890,092 - 56,900,008 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	57,369,935 - 57,379,846 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	57,571,141 - 57,581,071 (+)	NCBI		UU_Cfam_GSD_1.0

Klf16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	216,765,959 - 216,773,397 (+)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936588	1,061,386 - 1,068,351 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

KLF16
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	76,680,020 - 76,690,841 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	76,680,219 - 76,690,823 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	77,457,928 - 77,468,123 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

KLF16
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	1,657,265 - 1,668,431 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	1,659,316 - 1,668,327 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666081	7,159,757 - 7,170,928 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Klf16
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624828	6,933,630 - 6,942,347 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624828	6,933,480 - 6,944,238 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Klf16
196 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	920
Count of miRNA genes:	498
Interacting mature miRNAs:	595
Transcripts:	ENSMUST00000038558
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357740	Obsty3_m	obesity 3 (mouse)			Not determined		10	8235478	116190980	Mouse
1301386	Sysbp1_m	systolic blood pressure 1 (mouse)			Not determined		10	10108265	87401095	Mouse
1357825	Kidpq2_m	kidney weight percentage QTL 2 (mouse)			Not determined		10	12704051	84079784	Mouse
1357656	Hrtq3_m	heart weight QTL 3 (mouse)			Not determined		10	12704051	84079784	Mouse
1357864	Scfpq1_m	subcutaneous fat pad percentage QTL 1 (mouse)			Not determined		10	12704051	84079784	Mouse
39128215	Lwq17_m	liver weight QTL 17 (mouse)					10	12704051	84079784	Mouse
4141956	Egq7_m	early growth QTL 7 (mouse)			Not determined			12704051	84079784	Mouse
4141943	W6q6_m	weight 6 weeks QTL 6 (mouse)			Not determined			12704051	84079784	Mouse
4142272	W10q5_m	weight 10 weeks QTL 5 (mouse)			Not determined			12704051	84079784	Mouse
4142380	W3q11_m	weight 3 weeks QTL 11 (mouse)			Not determined			12704051	84079784	Mouse
1302067	Scc9_m	colon tumor susceptibility 9 (mouse)			Not determined		10	18259333	125575232	Mouse
27226772	Tibl13_m	tibia length 13, 10 week (mouse)					10	18875748	129635869	Mouse
1558757	Eae34_m	experimental allergic encephalomyelitis susceptibility 34 (mouse)			Not determined		10	21408154	114217230	Mouse
26884403	Cvht8_m	cranial vault height 8, 16 week (mouse)					10	22875899	91035862	Mouse
26884426	Cvht1_m	cranial vault height 1, 5 week (mouse)					10	24675898	121035905	Mouse
27095911	Pglq15_m	pelvic girdle length QTL 15, 16 week (mouse)					10	39175996	129635869	Mouse
27226764	Tibl19_m	tibia length 19, 16 week (mouse)					10	39175996	129635869	Mouse
26884411	Bzwq8_m	bi-zygomatic width QTL 8, 10 week (mouse)					10	44876096	115935905	Mouse
26884407	Bzwq14_m	bi-zygomatic width QTL 14, 16 wee (mouse)					10	45476096	120635905	Mouse
4142313	Angvq1_m	angiogenesis by VEGF QTL 1 (mouse)			Not determined			46720403	82491121	Mouse
1302150	Bbaa18_m	B.burgdorferi-associated arthritis 18 (mouse)			Not determined		10	49338012	83338157	Mouse
10045641	Jckm3_m	juvenile cystic kidney modifier 3 (mouse)			Not determined		10	49848187	83848412	Mouse
1300597	Skull14_m	skull morphology 14 (mouse)			Not determined		10	49848187	83848412	Mouse
4142169	Pbwg16_m	postnatal body weight growth 16 (mouse)			Not determined		10	49848187	83848412	Mouse
1357737	Hpcr2_m	hepatocarcinogen resistance 2 (mouse)			Not determined		10	49848222	83848397	Mouse
1301966	Lifespan2_m	life span 2 (mouse)			Not determined		10	49848222	83848397	Mouse
1301502	Eae17_m	susceptibility to experimental allergic encephalomyelitis 17 (mouse)			Not determined		10	51091490	85091639	Mouse
1300882	Ath17_m	atherosclerosis 17 (mouse)			Not determined		10	51091490	85091639	Mouse
1301380	Cia8_m	collagen induced arthritis QTL 8 (mouse)			Not determined		10	51493400	82491121	Mouse
14746991	Manh68_m	mandible shape 68 (mouse)					10	52280497	86280497	Mouse
1301787	Bsc1_m	brain size control 1 (mouse)			Not determined		10	58516969	92517096	Mouse
26884450	Sklq15_m	skull length QTL 15, 16 week (mouse)					10	59335822	122335905	Mouse
13208560	Wght9_m	weight 9 (mouse)					10	59835822	120835905	Mouse
26884424	Zlq9_m	zygomatic length QTL 9, 16 week (mouse)					10	63935779	115935905	Mouse
1302060	El3_m	epilepsy 3 (mouse)			Not determined		10	65490938	99491121	Mouse
1300533	Aem3_m	anti-erythrocyte autoantibody modifier 3 (mouse)			Not determined		10	65490938	99491121	Mouse
1301737	Insq9_m	insulin QTL 9 (mouse)			Not determined		10	65490938	99491121	Mouse
1302035	Lmb4_m	lupus in MRL and B6 F2 cross (mouse)			Not determined		10	66848187	92258673	Mouse
26884447	Sklq9_m	skull length QTL 9, 10 week (mouse)					10	67335830	111735905	Mouse
26884430	Zlq5_m	zygomatic length QTL 5, 10 week (mouse)					10	67835830	124835905	Mouse
26884405	Huml2_m	humerus length 2, 5 week (mouse)					10	69735830	130430862	Mouse
11039497	Ltpr5a_m	Leishmania tropica response 5a (mouse)					10	73506901	107507047	Mouse
4142107	Obrq12_m	obesity resistance QTL 12 (mouse)			Not determined			73987216	82491121	Mouse
11353832	Pcholq4_m	plasma cholesterol QTL 4 (mouse)					10	73987216	125515907	Mouse
11353843	Gluq1_m	blood glucose QTL 1 (mouse)					10	73987216	125515907	Mouse
1357632	Vtbt9_m	vertebral trabecular bone trait 9 (mouse)			Not determined		10	75338568	109338767	Mouse
4142137	Femwf3_m	femur work to failure 3 (mouse)			Not determined			75338568	109338767	Mouse
1300975	Fembrs3_m	femur breaking strength 3 (mouse)			Not determined		10	75338568	109338767	Mouse
11251717	Siim1_m	stress induced immobility 1 (mouse)					10	78381268	112381268	Mouse

Markers in Region

AI843742

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	10	80,567,287 - 80,567,387	UniSTS	GRCm38
MGSCv37	10	80,030,032 - 80,030,132	UniSTS	GRCm37
Celera	10	81,585,086 - 81,585,186	UniSTS
Cytogenetic Map	10	C1	UniSTS
Whitehead/MRC_RH	10	917.85	UniSTS

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_078477	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC152058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF283891	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK044577	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK154524	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK167841	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK167940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK213648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY186596	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC021615	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC038918	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC137609	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466553	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSMUST00000038558 ⟹ ENSMUSP00000048825

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	10	80,402,958 - 80,413,155 (-)	Ensembl
GRCm38.p6 Ensembl	10	80,567,124 - 80,577,321 (-)	Ensembl

RefSeq Acc Id:

NM_078477 ⟹ NP_510962

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	10	80,402,955 - 80,413,130 (-)	NCBI
GRCm38	10	80,567,121 - 80,577,296 (-)	ENTREZGENE
MGSCv37	10	80,029,866 - 80,040,041 (-)	RGD
Celera	10	81,584,920 - 81,595,095 (-)	RGD
cM Map	10		ENTREZGENE

Sequence:

show sequence

GCACTCTAGCAGCCGCTGCCGGCCGGACGGGCGTAGGTCCCACCGCCTCCGCTTCTCTCCCGCC
GCCGATTCCGTGTCTCCGCGTCCTTGCCCGGCATGTCGGCGGCCGTGGCGTGTGTGGATTACTT
TGCCGCCGACGTGCTCATGGCCATCTCCTCGGGAGCCGTGGTGCATCGCGGACGACCCGGCCCC
GAGGGCGCGGGCCCCGCTGCCGGTCTGGATGTGCGCGCCACGCGCCGCGAGGCCACGCCGCCGG
GGACCCCTGGGGCACCGCCACCGCCAGCTACGGCTCCGGGGCCGGGAGGCGCCACCGCTGCGCC
CCACCTGCTGGCCGCCAGCATCCTGGCCGATCTGAGAGGCGGGCCGGTAGTCGCCACCGCAGCC
AGCACCGCGGGGGGCACCTCTCCGGTCTCCTCCTCCTCAGCCGCTTCGTCTCCCTCTTCGGGCC
GCGCCCCCGGCGCCGCCAAAAGCCACCGCTGTCCCTTCCATGGCTGCGCCAAAGCCTATTACAA
GTCTTCGCACCTCAAGTCACACCTGCGGACTCACACAGGTGAGCGGCCCTTTGCCTGCGACTGG
CCTGGCTGTGACAAGAAGTTCGCCCGTTCTGATGAGCTGGCCCGCCACCACCGGACGCACACCG
GGGAGAAGCGCTTCCCCTGCCCCCTGTGTACCAAGCGGTTCACCCGAAGCGACCACCTGACCAA
GCACGCCCGGCGACATCCCGGCTTCCGCCCGGAACTCCTGCGACGACCTGGTGCCCGCAGCGTC
TCGCCCAGCGACTCGCTGCCCTGCAGCTTGGCTGGAAGCCCCACACCTAGCCCTGTCCCCAGCC
CAGCTCCTGCTGGCTTGTAGAGCCCTGACGTGTCCACCCTGAGTGGCCTCCTTACTGGGCCTCA
GCAGGGATTTCTATCAAGGGACACATCTGTCCTCTGGAGAGCCTGTGTCCTGGAGTTCCAGCCC
ACCTCAAGAAAGCAGCAAGGGGACTGAGAATGGACTTGGGTCACCTGGGGGGCCTGGGAGGTGG
CCTCAGGTTCTGTCTGTAAATAGCCATGGTTAACTGTCCTGTCCCCTCTGCAGGGACCCCAAAT
GGGCAGTTGGCAGGCCCCCCCATCCCTTCCTGCCACCCTCTGCTTTCCCTCCTGGGTGGCGTTG
GGCATGAAGCCTACCCCACTCCTTGTCTTCAGCCCCCTAGTCACCCCTCCAGGTTGGGACACAG
GTACACAGAGCCATAGGTGACTGGGGCTTCCCATGGGCCCCTACCTGTCCCCACTCCACTGAAA
GCCATTGGCGGAAGTTCAGGGAAATGGGGGGGGTGCAGCCTGGCTGACCCCCTTCCATGGGTAC
TCAAATCTCAGGTGTCCATAGGTTCTGCCCTCAATAAGGGCCCCCCACTCCCAGCCCCAGGGGT
ACAGGAGACCCACAGTTTTCAGAGAACTTAGGGCTGTGGGGTACAGGTGGGGCACGTGGAGGTG
CATCCCCCACATCCCCGCTCACCTTGGGTGTGGTGCTGGGCAGATGGGAAAGAAATTATTTATT
GTCCTCTCTGACTGCTGGTGTGGGGGGGCCTGGCTCCCCCTATCTGGGTGTGCATATGTGTGAG
AGAGACAGTGGGTGTCTGGTGCCTGGGGCTTAGCCTCCTTACTCCCACTGGGTTAGGGTCCCTG
AGTTTGGCCTTTGTGGCATTGCGTCTCAGACAATCTATAGGACCCCTGCGGCCATCGGGCTATG
GATACAGGGCTCTGGTCTGCCGTCATGTGCTCCACACTCTCGGGTGTCTGCAGAGGGTGGCCTT
GGACTCCAGGATTGGGAACAGGGCGTTCAGCTCCTGGACCTTCTGGGGTAGCTCGGGTTTTTTT
TTTTTTTGCACAGGATAGATTTATTTTTTTCAGGCTCTGAGTTCCATGTTCCAGTGGGGGTCCC
CTTGTGTGGCCGTCATCCTCAGGGGTGAGTGGGGAAGGTCTCAGGAGAGTCTACAGTAGGATCC
TCTACTACTGCAGACTGGATTTCTTTTCTAGAAAGGCAATTAGGGATTGCCACACACACACCAA
GAAATTGGGGACACAGAGAAAGTTGAGCTGCCCTGTGTTGGCTGTGGGGGGTTTACTGGCATTC
CCATTTGTTCCAGAATCTTCCATCATGAAATGAGGGAGGCTTTGGGTAATGCTACCTTTACCTG
AGCCTACATGAGGGAGGTCACCCTTCTGGAGCTGGGCTGAGGGCCCTGGGCCAGCTCCTCTCCT
GGGTACTTCCATTTGCCCCTTCTCTTTGGCCACAGAAATGAGATGCCTTAGTTTGCAGGGTGGG
TGGGGGGCTGGGGCCAATTCTTTTTGTCTTTTGGATGTATCTTGCTTCATCCCAGCTCCTGCTG
GTCTCCTGTCCTTCCTGTAAACAGGGGGAAAGGACTGAGGTTCTTAGGAGTTAACTCCATAAGC
AATCAGAGCTTTTCCGTGATGTCCTCCCCCAGCCCCCCAACTTCAGGTTCTGATTGATAACTGG
GACTTGGGTCTAACCATTGAAGGGTGATGAACGCAGGGCAGGCAGGACAAGGGTCCTAAGGGAT
TTATTTGTTCTTTCTGTAGGGGGCACCTCTCCTCCATTCCGCCTGGCCTCTCACCCATATATTT
AAATTAAAGAAGCCCTTTTTAAAAACCT

hide sequence

Protein Sequences


Protein RefSeqs	NP_510962	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI37608	(Get FASTA)	NCBI Sequence Viewer
	AAI37610	(Get FASTA)	NCBI Sequence Viewer
	AAK66968	(Get FASTA)	NCBI Sequence Viewer
	AAO31617	(Get FASTA)	NCBI Sequence Viewer
	BAC31987	(Get FASTA)	NCBI Sequence Viewer
	BAE32651	(Get FASTA)	NCBI Sequence Viewer
	EDL31532	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000048825
	ENSMUSP00000048825.9
GenBank Protein	P58334	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_510962 ⟸ NM_078477

- UniProtKB:

Q3U3Y4 (UniProtKB/Swiss-Prot), Q8C8S2 (UniProtKB/Swiss-Prot), P58334 (UniProtKB/Swiss-Prot), B2RPU7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSAAVACVDYFAADVLMAISSGAVVHRGRPGPEGAGPAAGLDVRATRREATPPGTPGAPPPPAT
APGPGGATAAPHLLAASILADLRGGPVVATAASTAGGTSPVSSSSAASSPSSGRAPGAAKSHRC
PFHGCAKAYYKSSHLKSHLRTHTGERPFACDWPGCDKKFARSDELARHHRTHTGEKRFPCPLCT
KRFTRSDHLTKHARRHPGFRPELLRRPGARSVSPSDSLPCSLAGSPTPSPVPSPAPAGL

hide sequence

RefSeq Acc Id:

ENSMUSP00000048825 ⟸ ENSMUST00000038558

Protein Domains

C2H2-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P58334-F1-model_v2	AlphaFold	P58334	1-251	view protein structure

Promoters

RGD ID:

6819486

Promoter ID:

MM_KWN:4889

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

3T3L1_Day0, 3T3L1_Day2, 3T3L1_Day3, 3T3L1_Day4, BoneMarrow_0Hour, BoneMarrow_2Hour, BoneMarrow_4Hour, Brain, ES_Cell, Kidney, Liver, Lung, MEF_B4, MEF_B6, Spleen

Transcripts:

ENSMUST00000038558

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	10	80,039,726 - 80,041,012 (-)	MPROMDB

RGD ID:

8672672

Promoter ID:

EPDNEW_M14367

Type:

initiation region

Name:

Klf16_1

Description:

Mus musculus Kruppel-like factor 16 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	10	80,577,294 - 80,577,354	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:2153049	AgrOrtholog
Ensembl Genes	ENSMUSG00000035397	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000038558	ENTREZGENE
	ENSMUST00000038558.9	UniProtKB/Swiss-Prot
Gene3D-CATH	Classic Zinc Finger	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Znf_C2H2_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_C2H2_type	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:118445	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:2153049	ENTREZGENE
NCBI Gene	118445	ENTREZGENE
PANTHER	KRUEPPEL-LIKE FACTOR 16	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	KRUEPPEL-LIKE TRANSCRIPTION FACTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	zf-C2H2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Klf16	PhenoGen
PROSITE	ZINC_FINGER_C2H2_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZINC_FINGER_C2H2_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART	ZnF_C2H2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF57667	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	B2RPU7	ENTREZGENE, UniProtKB/TrEMBL
	KLF16_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
	Q3U3Y4	ENTREZGENE
	Q8C8S2	ENTREZGENE
UniProt Secondary	Q3U3Y4	UniProtKB/Swiss-Prot
	Q8C8S2	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2023-05-02	Klf16	Kruppel-like transcription factor 16	Klf16	Kruppel-like factor 16	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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