Lats2 (large tumor suppressor 2) - Rat Genome Database
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Gene: Lats2 (large tumor suppressor 2) Mus musculus
Analyze
Symbol: Lats2
Name: large tumor suppressor 2
RGD ID: 1314217
MGI Page MGI
Description: Predicted to have ATP binding activity and protein serine/threonine kinase activity. Involved in several processes, including G1/S transition of mitotic cell cycle; hippo signaling; and inner cell mass cell differentiation. Localizes to spindle pole. Is expressed in several structures, including central nervous system; eye; genitourinary system; gut; and immune system. Orthologous to human LATS2 (large tumor suppressor kinase 2); INTERACTS WITH 1,2-dimethylhydrazine; 2,3',4,4',5-Pentachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4932411G09Rik; AV277261; AW228608; kinase phosphorylated during mitosis protein; large tumor suppressor homolog 2; serine/threonine-protein kinase kpm; serine/threonine-protein kinase LATS2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391457,927,119 - 57,983,669 (-)NCBIGRCm39mm39
GRCm381457,689,662 - 57,746,212 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1457,642,077 - 57,746,103 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1457,689,662 - 57,758,388 (-)EnsemblGRCm38mm10GRCm38
MGSCv371458,308,499 - 58,364,960 (-)NCBIGRCm37mm9NCBIm37
MGSCv361456,643,772 - 56,700,233 (-)NCBImm8
Celera1455,491,594 - 55,547,812 (-)NCBICelera
Cytogenetic Map14C3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-methoxyethanol  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (EXP,ISO)
aflatoxin B2  (ISO)
antirheumatic drug  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (ISO)
bisphenol F  (EXP)
C60 fullerene  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
choline  (EXP)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (EXP,ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibutyl phthalate  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (EXP)
fisetin  (ISO)
folic acid  (EXP)
formaldehyde  (ISO)
hydrogen peroxide  (ISO)
L-methionine  (EXP)
menadione  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
oxaliplatin  (ISO)
paracetamol  (EXP)
phenobarbital  (EXP)
potassium chromate  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
tetrachloromethane  (EXP)
thalidomide  (ISO)
titanium dioxide  (EXP)
topotecan  (ISO)
trichostatin A  (ISO)
troglitazone  (EXP)
tungsten  (EXP)
urethane  (ISO)
valproic acid  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10523652   PMID:10673337   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:14610273   PMID:15343267   PMID:15489334  
PMID:15782199   PMID:16141072   PMID:16141073   PMID:17478426   PMID:18369314   PMID:18927464   PMID:18973680   PMID:19289085   PMID:19786569   PMID:19906978   PMID:20643348   PMID:21145499  
PMID:21233212   PMID:21267068   PMID:21512031   PMID:21677750   PMID:21873635   PMID:22828209   PMID:23230145   PMID:23644383   PMID:23824537   PMID:23977200   PMID:24080911   PMID:24255096  
PMID:24413153   PMID:24525530   PMID:25659841   PMID:25787764   PMID:25912685   PMID:26109051   PMID:27013235   PMID:27160901   PMID:27358050   PMID:27405641   PMID:27434182   PMID:27480037  
PMID:27531557   PMID:27912060   PMID:28087714   PMID:28195124   PMID:28457749   PMID:28486106   PMID:28492365   PMID:28805663   PMID:28943241   PMID:28973878   PMID:29249622   PMID:29438698  
PMID:29632206   PMID:29669762   PMID:29689192   PMID:29849151   PMID:30286078   PMID:30305289   PMID:30348677   PMID:30523785   PMID:30582452   PMID:30912742   PMID:31067451   PMID:31268774  
PMID:31323030   PMID:31474569   PMID:31513574   PMID:31558567   PMID:31575647   PMID:31754005   PMID:31980640   PMID:32015438   PMID:32243503   PMID:32289155   PMID:32341094   PMID:32404936  
PMID:32451369  


Genomics

Comparative Map Data
Lats2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391457,927,119 - 57,983,669 (-)NCBIGRCm39mm39
GRCm381457,689,662 - 57,746,212 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1457,642,077 - 57,746,103 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1457,689,662 - 57,758,388 (-)EnsemblGRCm38mm10GRCm38
MGSCv371458,308,499 - 58,364,960 (-)NCBIGRCm37mm9NCBIm37
MGSCv361456,643,772 - 56,700,233 (-)NCBImm8
Celera1455,491,594 - 55,547,812 (-)NCBICelera
Cytogenetic Map14C3NCBI
LATS2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1320,973,036 - 21,061,586 (-)EnsemblGRCh38hg38GRCh38
GRCh381320,973,036 - 21,061,586 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371321,547,175 - 21,635,722 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361320,445,175 - 20,533,722 (-)NCBINCBI36hg18NCBI36
Build 341320,446,578 - 20,533,654NCBI
Celera132,609,110 - 2,697,695 (-)NCBI
Cytogenetic Map13q12.11NCBI
HuRef132,350,083 - 2,438,773 (-)NCBIHuRef
CHM1_11321,515,524 - 21,603,910 (-)NCBICHM1_1
Lats2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01537,943,609 - 37,995,175 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1537,943,609 - 37,983,882 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01541,788,720 - 41,828,866 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41536,720,000 - 36,761,065 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11536,737,366 - 36,776,640 (-)NCBI
Celera1531,535,661 - 31,575,853 (-)NCBICelera
Cytogenetic Map15p12NCBI
Lats2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554971,711,205 - 1,761,584 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554971,711,882 - 1,768,177 (-)NCBIChiLan1.0ChiLan1.0
LATS2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11320,610,022 - 20,698,810 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1320,611,861 - 20,683,083 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0132,300,625 - 2,389,027 (-)NCBIMhudiblu_PPA_v0panPan3
LATS2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2517,110,637 - 17,169,291 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12517,110,620 - 17,169,826 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Lats2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936720735,326 - 795,596 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LATS2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl111,225,527 - 1,265,946 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1111,225,523 - 1,265,970 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LATS2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.13124,520 - 215,426 (+)NCBI
Lats2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462477616,572,598 - 16,640,412 (+)NCBI

Position Markers
AW228608  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381457,689,840 - 57,689,974UniSTSGRCm38
MGSCv371458,308,677 - 58,308,811UniSTSGRCm37
Celera1455,491,772 - 55,491,906UniSTS
Cytogenetic Map14C3UniSTS
Whitehead/MRC_RH14661.28UniSTS
Lats2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map14C3UniSTS
cM Map14 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12880432Fgf23lq3_mFGF23 serum level QTL 3 (mouse)145370000087700000Mouse
4141484Hcbip1_mhexachlorobenzene induced porphyria 1 (mouse)Not determined4709779359725144Mouse
27226737Metcl12_mmetatarsal-calcaneal length 12, 10 week (mouse)143350000059200000Mouse
4141400Nilac8_mnicotine induced locomotor activity 8 (mouse)Not determined144282839876828596Mouse
1300805Mors3_mmodifier of obesity related sterility 3 (mouse)Not determined144279982176799969Mouse
1301424Skull21_mskull morphology 21 (mouse)Not determined144272496776725144Mouse
1301562Hwq1_mheart weight quantitative locus 1 (mouse)Not determined145630930590309501Mouse
1300998Cia17_mcollagen induced arthritis 17 (mouse)Not determined143009779364097924Mouse
1300605El5_mepilepsy 5 (mouse)Not determined144921797683218107Mouse
1301777Bglq15_mbody growth late QTL 15 (mouse)Not determined144272496776725144Mouse
27226774Tibl15_mtibia length 15, 10 week (mouse)143060000087700000Mouse
1300625Cosz2_mcocaine seizure 2 (mouse)Not determined143532384068548287Mouse
13506929Recrq10_mrecombination rate in male meiosis QTL 10 (mouse)142820000060900000Mouse
4142364Pbwg18_mpostnatal body weight growth 18 (mouse)Not determined145204453586044676Mouse
1300909Ath13_matherosclerosis 13 (mouse)Not determined143009779364097924Mouse
4142419Tgq26_mtriglyceride QTL 26 (mouse)Not determined4009986274099862Mouse
1301489Lbm10_mlean body mass 10 (mouse)Not determined145352385687524089Mouse
4142485Modor2_mmodifier of ocular retardation 2 (mouse)Not determined142492582457942312Mouse
10043889Cia52_mcollagen induced arthritis QTL 52 (mouse)Not determined145584494189845069Mouse
10043887Cia50_mcollagen induced arthritis QTL 50 (mouse)Not determined143719272871192863Mouse
1301091Bbaa21_mB.burgdorferi-associated arthritis 21 (mouse)Not determined144282839876828596Mouse
1357589Kdnw2_mkidney weight 2 (mouse)Not determined1420837405121032392Mouse
10043886Cia49_mcollagen induced arthritis QTL 49 (mouse)Not determined142975953763759676Mouse
1357527Epfpq1_mepididymal fat percentage QTL 1 (mouse)Not determined142101238271648361Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir31mmu-miR-31-5pMirecordsexternal_infoNANA20237410
Mir31mmu-miR-31-5pOncomiRDBexternal_infoNANA20237410

Predicted Target Of
Summary Value
Count of predictions:2720
Count of miRNA genes:890
Interacting mature miRNAs:1222
Transcripts:ENSMUST00000022531, ENSMUST00000038381, ENSMUST00000077981, ENSMUST00000173077, ENSMUST00000173732, ENSMUST00000173964, ENSMUST00000173990, ENSMUST00000174166, ENSMUST00000174213, ENSMUST00000174694
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_015771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_153382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006519225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB023958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB028209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC154504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK029966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK137436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK163607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164789 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK198862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK203330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY015061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY015062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024819 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC053028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF147719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU705730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY442318 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000022531   ⟹   ENSMUSP00000022531
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,689,662 - 57,746,123 (-)Ensembl
RefSeq Acc Id: ENSMUST00000038381   ⟹   ENSMUSP00000038982
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,722,189 - 57,734,300 (-)Ensembl
RefSeq Acc Id: ENSMUST00000077981   ⟹   ENSMUSP00000077130
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,722,189 - 57,734,300 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173077
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,734,253 - 57,746,578 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173732   ⟹   ENSMUSP00000133857
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,734,180 - 57,744,654 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173964   ⟹   ENSMUSP00000134142
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,697,227 - 57,699,890 (-)Ensembl
RefSeq Acc Id: ENSMUST00000173990   ⟹   ENSMUSP00000133976
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,693,544 - 57,746,105 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174166   ⟹   ENSMUSP00000133379
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,703,051 - 57,758,388 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174213   ⟹   ENSMUSP00000134321
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,691,098 - 57,746,121 (-)Ensembl
RefSeq Acc Id: ENSMUST00000174694   ⟹   ENSMUSP00000133680
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1457,642,077 - 57,746,103 (-)Ensembl
RefSeq Acc Id: NM_015771   ⟹   NP_056586
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391457,927,119 - 57,983,580 (-)NCBI
GRCm381457,689,662 - 57,746,123 (-)ENTREZGENE
MGSCv371458,308,499 - 58,364,960 (-)RGD
Celera1455,491,594 - 55,547,812 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_153382   ⟹   NP_700431
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391457,959,646 - 57,971,875 (-)NCBI
GRCm381457,722,189 - 57,734,418 (-)NCBI
MGSCv371458,308,499 - 58,364,960 (-)RGD
Celera1455,491,594 - 55,547,812 (-)RGD
cM Map14 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006519224   ⟹   XP_006519287
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391457,927,119 - 57,983,669 (-)NCBI
GRCm381457,689,662 - 57,746,212 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006519225   ⟹   XP_006519288
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391457,959,646 - 57,983,548 (-)NCBI
GRCm381457,722,189 - 57,746,125 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_056586   ⟸   NM_015771
- Peptide Label: isoform 1
- UniProtKB: Q7TSJ6 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_700431   ⟸   NM_153382
- Peptide Label: isoform 2
- UniProtKB: Q8VHE2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006519287   ⟸   XM_006519224
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006519288   ⟸   XM_006519225
- Peptide Label: isoform X2
- UniProtKB: Q8VHE2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000133680   ⟸   ENSMUST00000174694
RefSeq Acc Id: ENSMUSP00000133379   ⟸   ENSMUST00000174166
RefSeq Acc Id: ENSMUSP00000134321   ⟸   ENSMUST00000174213
RefSeq Acc Id: ENSMUSP00000022531   ⟸   ENSMUST00000022531
RefSeq Acc Id: ENSMUSP00000133857   ⟸   ENSMUST00000173732
RefSeq Acc Id: ENSMUSP00000134142   ⟸   ENSMUST00000173964
RefSeq Acc Id: ENSMUSP00000133976   ⟸   ENSMUST00000173990
RefSeq Acc Id: ENSMUSP00000038982   ⟸   ENSMUST00000038381
RefSeq Acc Id: ENSMUSP00000077130   ⟸   ENSMUST00000077981
Protein Domains
AGC-kinase C-terminal   Protein kinase   UBA

Promoters
RGD ID:8682560
Promoter ID:EPDNEW_M19310
Type:single initiation site
Name:Lats2_2
Description:Mus musculus large tumor suppressor 2 , transcript variant A,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19311  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381457,694,444 - 57,694,504EPDNEW
RGD ID:8682562
Promoter ID:EPDNEW_M19311
Type:initiation region
Name:Lats2_1
Description:Mus musculus large tumor suppressor 2 , transcript variant A,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M19310  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381457,746,108 - 57,746,168EPDNEW
RGD ID:6847113
Promoter ID:MM_ACW:16170
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Lung
Transcripts:LATS2.JSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361458,310,196 - 58,310,696 (-)MPROMDB
RGD ID:6847111
Promoter ID:MM_ACW:16171
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   Kidney,   Liver,   Lung
Transcripts:LATS2.ESEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361458,318,391 - 58,318,977 (-)MPROMDB
RGD ID:6825109
Promoter ID:MM_KWN:17066
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6,   Spleen
Transcripts:UC007UDM.1,   UC007UDN.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361458,353,506 - 58,354,006 (-)MPROMDB
RGD ID:6847112
Promoter ID:MM_ACW:16172
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Brain
Transcripts:LATS2.ISEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361458,364,131 - 58,364,631 (-)MPROMDB
RGD ID:6825108
Promoter ID:MM_KWN:17067
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000038381,   ENSMUST00000077981,   NM_015771,   UC007UDJ.1,   UC007UDL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361458,364,531 - 58,365,452 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1354386 AgrOrtholog
Ensembl Genes ENSMUSG00000021959 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSMUSG00000114942 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000022531 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000038982 UniProtKB/TrEMBL
  ENSMUSP00000077130 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000133379 UniProtKB/TrEMBL
  ENSMUSP00000133680 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000133857 UniProtKB/TrEMBL
  ENSMUSP00000133976 UniProtKB/TrEMBL
  ENSMUSP00000134142 UniProtKB/TrEMBL
  ENSMUSP00000134321 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000022531 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000038381 UniProtKB/TrEMBL
  ENSMUST00000077981 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000173732 UniProtKB/TrEMBL
  ENSMUST00000173964 UniProtKB/TrEMBL
  ENSMUST00000173990 UniProtKB/TrEMBL
  ENSMUST00000174166 UniProtKB/TrEMBL
  ENSMUST00000174213 UniProtKB/TrEMBL
  ENSMUST00000174694 ENTREZGENE, UniProtKB/TrEMBL
InterPro AGC-kinase_C UniProtKB/Swiss-Prot
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LATS2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:50523 UniProtKB/Swiss-Prot
MGD MGI:1354386 ENTREZGENE
NCBI Gene 50523 ENTREZGENE
PANTHER PTHR24356:SF149 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lats2 PhenoGen
PROSITE AGC_KINASE_CTER UniProtKB/Swiss-Prot
  PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  UBA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TK_X UniProtKB/Swiss-Prot
  S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF46934 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt G3UWQ0_MOUSE UniProtKB/TrEMBL
  G3UXG3_MOUSE UniProtKB/TrEMBL
  G3UXX1_MOUSE UniProtKB/TrEMBL
  G3UY78_MOUSE UniProtKB/TrEMBL
  G3UYM3_MOUSE UniProtKB/TrEMBL
  G3UZ29_MOUSE UniProtKB/TrEMBL
  LATS2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8VHE1_MOUSE UniProtKB/TrEMBL
  Q8VHE2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q8CDJ4 UniProtKB/Swiss-Prot
  Q9JMI3 UniProtKB/Swiss-Prot