Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | CALN1 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of CALN1 mRNA | CTD | PMID:24763279 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CALN1 mRNA | CTD | PMID:17942748 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CALN1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CALN1 mRNA | CTD | PMID:19684285 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CALN1 mRNA | CTD | PMID:19684285 | 2,4-dibromophenyl 2,4,5-tribromophenyl ether | increases expression | ISO | CALN1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:26705709 | 3-chloropropane-1,2-diol | decreases expression | ISO | Caln1 (Rattus norvegicus) | 6480464 | alpha-Chlorohydrin results in decreased expression of CALN1 mRNA | CTD | PMID:28522335 | 6-propyl-2-thiouracil | increases expression | ISO | Caln1 (Rattus norvegicus) | 6480464 | Propylthiouracil results in increased expression of CALN1 mRNA | CTD | PMID:24780913 | 8-Br-cAMP | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in decreased expression of CALN1 mRNA | CTD | PMID:22079614 | aflatoxin B1 | affects expression | ISO | CALN1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of CALN1 protein | CTD | PMID:20106945 | aflatoxin B1 | affects methylation | ISO | CALN1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of CALN1 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | affects methylation | ISO | CALN1 (Homo sapiens) | 6480464 | aflatoxin B2 affects the methylation of CALN1 intron | CTD | PMID:30157460 | all-trans-retinoic acid | multiple interactions | EXP | | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CALN1 mRNA | CTD | PMID:36189433 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of CALN1 mRNA | CTD | PMID:36189433 | arsenite(3-) | increases methylation | ISO | CALN1 (Homo sapiens) | 6480464 | arsenite results in increased methylation of CALN1 promoter | CTD | PMID:23974009 | atrazine | affects methylation | ISO | Caln1 (Rattus norvegicus) | 6480464 | Atrazine affects the methylation of CALN1 gene | CTD | PMID:28931070 | benzo[a]pyrene | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of CALN1 mRNA | CTD | PMID:20106945 | benzo[a]pyrene | affects methylation | ISO | CALN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of CALN1 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases methylation | ISO | CALN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of CALN1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of CALN1 mRNA | CTD | PMID:22316170 | benzo[e]pyrene | affects methylation | ISO | CALN1 (Homo sapiens) | 6480464 | benzo(e)pyrene affects the methylation of CALN1 intron | CTD | PMID:30157460 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of CALN1 mRNA | CTD | PMID:31163220 | bisphenol A | decreases expression | ISO | Caln1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of CALN1 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of CALN1 mRNA | CTD | PMID:32156529 | bisphenol A | multiple interactions | ISO | CALN1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CALN1 gene | CTD | PMID:31601247 | bisphenol A | increases expression | ISO | Caln1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of CALN1 mRNA | CTD | PMID:29097150 | bisphenol A | increases methylation | ISO | Caln1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of CALN1 gene | CTD | PMID:28505145 | bisphenol F | increases methylation | ISO | CALN1 (Homo sapiens) | 6480464 | bisphenol F results in increased methylation of CALN1 gene | CTD | PMID:31601247 | carbamazepine | affects expression | ISO | CALN1 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of CALN1 mRNA | CTD | PMID:25979313 | carbon nanotube | increases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in increased expression of CALN1 mRNA | CTD | PMID:25620056 | chlordecone | affects response to substance | ISO | CALN1 (Homo sapiens) | 6480464 | CALN1 gene SNP affects the susceptibility to Chlordecone | CTD | PMID:25622337 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CALN1 gene | CTD | PMID:20938992 | copper atom | multiple interactions | ISO | Caln1 (Rattus norvegicus) | 6480464 | [Copper co-treated with Dietary Sucrose] results in decreased expression of CALN1 mRNA | CTD | PMID:26033743 | copper(0) | multiple interactions | ISO | Caln1 (Rattus norvegicus) | 6480464 | [Copper co-treated with Dietary Sucrose] results in decreased expression of CALN1 mRNA | CTD | PMID:26033743 | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos and Crocidolite results in increased expression of CALN1 mRNA | CTD | PMID:29279043 | cyclosporin A | decreases methylation | ISO | CALN1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of CALN1 promoter | CTD | PMID:27989131 | dorsomorphin | multiple interactions | ISO | CALN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | affects methylation | ISO | Caln1 (Rattus norvegicus) | 6480464 | Doxorubicin affects the methylation of CALN1 gene | CTD | PMID:28962528 | doxorubicin | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of CALN1 mRNA | CTD | PMID:30031762 | entinostat | increases expression | ISO | CALN1 (Homo sapiens) | 6480464 | entinostat results in increased expression of CALN1 mRNA | CTD | PMID:27188386 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of CALN1 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of CALN1 mRNA | CTD | PMID:23649840 | folic acid | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CALN1 gene | CTD | PMID:20938992 | fonofos | increases methylation | ISO | CALN1 (Homo sapiens) | 6480464 | Fonofos results in increased methylation of CALN1 promoter | CTD | PMID:22847954 | formaldehyde | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of CALN1 mRNA | CTD | PMID:23649840 | fulvestrant | multiple interactions | ISO | CALN1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of CALN1 gene | CTD | PMID:31601247 | fulvestrant | increases methylation | ISO | CALN1 (Homo sapiens) | 6480464 | Fulvestrant results in increased methylation of CALN1 gene | CTD | PMID:31601247 | furan | decreases expression | ISO | Caln1 (Rattus norvegicus) | 6480464 | furan results in decreased expression of CALN1 mRNA | CTD | PMID:25539665 | glyphosate | increases methylation | ISO | Caln1 (Rattus norvegicus) | 6480464 | Glyphosate results in increased methylation of CALN1 gene | CTD | PMID:31011160 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of CALN1 gene | CTD | PMID:20938992 | lead(0) | affects expression | ISO | CALN1 (Homo sapiens) | 6480464 | Lead affects the expression of CALN1 mRNA | CTD | PMID:28903495 | maneb | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of CALN1 mRNA | CTD | PMID:36117858 | methapyrilene | affects methylation | ISO | CALN1 (Homo sapiens) | 6480464 | Methapyrilene affects the methylation of CALN1 intron | CTD | PMID:30157460 | methotrexate | affects expression | EXP | | 6480464 | Methotrexate affects the expression of CALN1 mRNA | CTD | PMID:18502557 | methotrexate | increases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Methotrexate results in increased expression of CALN1 mRNA | CTD | PMID:24449571 | methyl methanesulfonate | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of CALN1 mRNA | CTD | PMID:23649840 | mono(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of CALN1 mRNA | CTD | PMID:36189433 | N,N-diethyl-m-toluamide | multiple interactions | ISO | Caln1 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of CALN1 gene | CTD | PMID:33148267 | O-methyleugenol | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of CALN1 mRNA | CTD | PMID:32234424 | p-chloromercuribenzoic acid | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of CALN1 mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | CALN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CALN1 mRNA | CTD | PMID:27188386 | paracetamol | increases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of CALN1 mRNA | CTD | PMID:29067470 | paraquat | multiple interactions | EXP | | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of CALN1 mRNA | CTD | PMID:36117858 | parathion | increases methylation | ISO | CALN1 (Homo sapiens) | 6480464 | Parathion results in increased methylation of CALN1 promoter | CTD | PMID:22847954 | permethrin | multiple interactions | ISO | Caln1 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of CALN1 gene | CTD | PMID:33148267 | phenylmercury acetate | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of CALN1 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | CALN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of CALN1 mRNA | CTD | PMID:27188386 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of CALN1 mRNA | CTD | PMID:18301758 and PMID:23811191 | progesterone | decreases expression | EXP | | 6480464 | Progesterone results in decreased expression of CALN1 mRNA | CTD | PMID:22238285 | SB 431542 | multiple interactions | ISO | CALN1 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | decreases expression | ISO | CALN1 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of CALN1 mRNA | CTD | PMID:21457566 | sodium arsenite | affects methylation | ISO | CALN1 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of CALN1 gene | CTD | PMID:28589171 | terbufos | increases methylation | ISO | CALN1 (Homo sapiens) | 6480464 | terbufos results in increased methylation of CALN1 promoter | CTD | PMID:22847954 | testosterone | increases expression | EXP | | 6480464 | Testosterone deficiency results in increased expression of CALN1 mRNA | CTD | PMID:33848595 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of CALN1 mRNA | CTD | PMID:29264374 | trichloroethene | increases methylation | ISO | Caln1 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased methylation of CALN1 gene | CTD | PMID:27618143 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of CALN1 mRNA | CTD | PMID:17963808 | valproic acid | affects expression | ISO | CALN1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of CALN1 mRNA | CTD | PMID:25979313 | |