DSP (desmoplakin) - Rat Genome Database

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Gene: DSP (desmoplakin) Homo sapiens
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Symbol: DSP
Name: desmoplakin
RGD ID: 1314043
HGNC Page HGNC
Description: Enables protein kinase C binding activity and scaffold protein binding activity. Involved in keratinocyte differentiation; peptide cross-linking; and regulation of heart contraction. Acts upstream of or within epithelial cell-cell adhesion. Located in cornified envelope and intercalated disc. Implicated in Carvajal syndrome; arrhythmogenic right ventricular cardiomyopathy; arrhythmogenic right ventricular dysplasia 8; and dilated cardiomyopathy. Biomarker of hypertrophic cardiomyopathy.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: 250/210 kDa paraneoplastic pemphigus antigen; DCWHKTA; desmoplakin I; desmoplakin II; DP; DPI; DPII
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3867,541,671 - 7,586,714 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl67,541,617 - 7,586,714 (+)EnsemblGRCh38hg38GRCh38
GRCh3767,541,904 - 7,586,947 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3667,486,869 - 7,531,945 (+)NCBINCBI36hg18NCBI36
Build 3467,486,868 - 7,531,945NCBI
Celera68,771,623 - 8,816,711 (+)NCBI
Cytogenetic Map6p24.3NCBI
HuRef67,419,476 - 7,464,417 (+)NCBIHuRef
CHM1_167,544,023 - 7,589,106 (+)NCBICHM1_1
T2T-CHM13v2.067,410,711 - 7,455,759 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model