1,2-dimethylhydrazine affects expression EXP 6480464 1 and 2-Dimethylhydrazine affects the expression of PXN mRNA CTD PMID:22206623 1,8-cineole multiple interactions EXP 6480464 Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein] more ... CTD PMID:31483951 17beta-estradiol multiple interactions ISO PXN (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in increased expression of PXN mRNA and EGF protein inhibits the reaction [Estradiol results in decreased expression of PXN mRNA] CTD PMID:24758408 and PMID:30165855 17beta-estradiol increases phosphorylation ISO PXN (Homo sapiens) 6480464 Estradiol results in increased phosphorylation of PXN protein CTD PMID:27026707 17beta-estradiol affects expression ISO PXN (Homo sapiens) 6480464 Estradiol affects the expression of PXN mRNA CTD PMID:22574217 17beta-estradiol decreases expression ISO PXN (Homo sapiens) 6480464 Estradiol results in decreased expression of PXN mRNA CTD PMID:24758408 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PXN mRNA CTD PMID:21570461 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Pxn (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of PXN mRNA CTD PMID:34747641 2,4-dinitrotoluene affects expression ISO Pxn (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of PXN mRNA CTD PMID:21346803 2,6-dinitrotoluene affects expression ISO Pxn (Rattus norvegicus) 6480464 2 and 6-dinitrotoluene affects the expression of PXN mRNA CTD PMID:21346803 4,4'-diaminodiphenylmethane decreases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of PXN mRNA CTD PMID:18648102 4,4'-sulfonyldiphenol decreases methylation EXP 6480464 bisphenol S results in decreased methylation of PXN exon CTD PMID:33297965 4-hydroxycoumarin decreases phosphorylation EXP 6480464 4-hydroxycoumarin results in decreased phosphorylation of PXN protein CTD PMID:18492274 4-hydroxycoumarin affects localization EXP 6480464 4-hydroxycoumarin affects the localization of PXN protein CTD PMID:18492274 4-hydroxycoumarin decreases expression EXP 6480464 4-hydroxycoumarin results in decreased expression of PXN mRNA alternative form and 4-hydroxycoumarin results in decreased expression of PXN protein alternative form CTD PMID:18492274 4-hydroxyphenyl retinamide increases expression EXP 6480464 Fenretinide results in increased expression of PXN mRNA CTD PMID:28973697 4-vinylcyclohexene dioxide affects expression EXP 6480464 4-vinyl-1-cyclohexene dioxide affects the expression of PXN mRNA CTD PMID:20829426 acetylsalicylic acid decreases expression ISO PXN (Homo sapiens) 6480464 Aspirin results in decreased expression of PXN mRNA CTD PMID:15928584 acrolein multiple interactions ISO PXN (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PXN mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PXN mRNA CTD PMID:32699268 aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of PXN protein modified form CTD PMID:31483951 aldehydo-D-glucose multiple interactions EXP 6480464 Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein] more ... CTD PMID:31483951 aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of PXN protein CTD PMID:31483951 all-trans-retinoic acid increases expression ISO PXN (Homo sapiens) 6480464 Tretinoin results in increased expression of PXN and Tretinoin results in increased expression of PXN mRNA CTD PMID:24819975 more ... all-trans-retinoic acid multiple interactions ISO PXN (Homo sapiens) 6480464 [LCP2 protein co-treated with CSF1R protein] promotes the reaction [Tretinoin results in increased expression of PXN protein] and SUMO1 mutant form inhibits the reaction [Tretinoin results in increased expression of PXN mRNA] CTD PMID:16439309 and PMID:24819975 alpha-pinene multiple interactions ISO PXN (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PXN mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of PXN mRNA CTD PMID:32699268 Anetholtrithion multiple interactions ISO PXN (Homo sapiens) 6480464 Anethole Trithione inhibits the reaction [Reactive Oxygen Species results in increased phosphorylation of PXN protein] CTD PMID:11213483 aristolochic acid A increases expression ISO PXN (Homo sapiens) 6480464 aristolochic acid I results in increased expression of PXN mRNA CTD PMID:33212167 arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of PXN mRNA CTD PMID:33053406 atropine multiple interactions ISO PXN (Homo sapiens) 6480464 Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 benzo[a]pyrene decreases expression ISO PXN (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of PXN mRNA and Benzo(a)pyrene results in decreased expression of PXN protein CTD PMID:31255691 and PMID:32717239 benzo[a]pyrene increases expression ISO PXN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased expression of PXN mRNA CTD PMID:32234424 benzo[a]pyrene affects methylation ISO PXN (Homo sapiens) 6480464 Benzo(a)pyrene affects the methylation of PXN 5' UTR CTD PMID:27901495 benzo[a]pyrene increases methylation ISO PXN (Homo sapiens) 6480464 Benzo(a)pyrene results in increased methylation of PXN promoter CTD PMID:27901495 bis(2-ethylhexyl) phthalate increases expression ISO PXN (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of PXN mRNA CTD PMID:31163220 bisphenol A affects expression ISO Pxn (Rattus norvegicus) 6480464 bisphenol A affects the expression of PXN mRNA CTD PMID:25181051 bisphenol A increases expression ISO PXN (Homo sapiens) 6480464 bisphenol A results in increased expression of PXN protein CTD PMID:37567409 bisphenol A decreases expression ISO PXN (Homo sapiens) 6480464 bisphenol A results in decreased expression of PXN protein CTD PMID:34186270 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of PXN mRNA CTD PMID:32156529 bisphenol A multiple interactions ISO PXN (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PXN gene CTD PMID:31601247 Bisphenol B increases expression ISO PXN (Homo sapiens) 6480464 bisphenol B results in increased expression of PXN protein CTD PMID:34186270 BQ 123 multiple interactions ISO PXN (Homo sapiens) 6480464 [BQ 788 co-treated with cyclo(Trp-Asp-Pro-Val-Leu)] inhibits the reaction [EDN1 protein results in increased phosphorylation of PXN protein] CTD PMID:12875994 cadmium atom increases expression ISO PXN (Homo sapiens) 6480464 Cadmium results in increased expression of PXN mRNA CTD PMID:22562489 cadmium atom multiple interactions ISO PXN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PXN mRNA CTD PMID:35301059 cadmium dichloride increases expression ISO PXN (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of PXN protein CTD PMID:28527916 cadmium dichloride multiple interactions ISO PXN (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of PXN mRNA CTD PMID:35301059 caffeine affects phosphorylation ISO PXN (Homo sapiens) 6480464 Caffeine affects the phosphorylation of PXN protein CTD PMID:35688186 calciol increases expression ISO PXN (Homo sapiens) 6480464 Cholecalciferol results in increased expression of PXN CTD PMID:9081214 carbamazepine affects expression ISO PXN (Homo sapiens) 6480464 Carbamazepine affects the expression of PXN mRNA CTD PMID:25979313 chlorpyrifos increases expression ISO Pxn (Rattus norvegicus) 6480464 Chlorpyrifos results in increased expression of PXN mRNA CTD PMID:20691718 chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of PXN mRNA CTD PMID:32715474 and PMID:37019170 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of PXN mRNA CTD PMID:21151649 cobalt dichloride decreases expression ISO PXN (Homo sapiens) 6480464 cobaltous chloride results in decreased expression of PXN mRNA CTD PMID:19320972 coumarin affects phosphorylation ISO PXN (Homo sapiens) 6480464 coumarin affects the phosphorylation of PXN protein CTD PMID:35688186 cyclosporin A increases expression ISO PXN (Homo sapiens) 6480464 Cyclosporine results in increased expression of PXN mRNA CTD PMID:25562108 D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of PXN protein CTD PMID:31483951 D-glucose increases expression EXP 6480464 Glucose results in increased expression of PXN protein modified form CTD PMID:31483951 D-glucose multiple interactions EXP 6480464 Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein] more ... CTD PMID:31483951 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of PXN mRNA CTD PMID:21266533 dicrotophos increases expression ISO PXN (Homo sapiens) 6480464 dicrotophos results in increased expression of PXN mRNA CTD PMID:28302478 Dictamnine decreases phosphorylation ISO PXN (Homo sapiens) 6480464 dictamnine results in decreased phosphorylation of PXN protein CTD PMID:34861243 dieldrin increases response to substance ISO PXN (Homo sapiens) 6480464 PXN gene mutant form results in increased susceptibility to Dieldrin CTD PMID:32421776 diethyl maleate increases expression ISO PXN (Homo sapiens) 6480464 diethyl maleate results in increased expression of PXN mRNA CTD PMID:33545341 disodium selenite decreases expression ISO PXN (Homo sapiens) 6480464 Sodium Selenite results in decreased expression of PXN mRNA CTD PMID:18175754 dorsomorphin multiple interactions ISO PXN (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PXN mRNA CTD PMID:27188386 endosulfan decreases expression ISO PXN (Homo sapiens) 6480464 Endosulfan results in decreased expression of PXN mRNA CTD PMID:28108160 and PMID:30090376 endosulfan decreases expression ISO Pxn (Rattus norvegicus) 6480464 Endosulfan results in decreased expression of PXN mRNA CTD PMID:29391264 enzyme inhibitor multiple interactions ISO PXN (Homo sapiens) 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PXN protein CTD PMID:23301498 ethanol increases expression EXP 6480464 Ethanol results in increased expression of PXN mRNA CTD PMID:30319688 formaldehyde multiple interactions ISO PXN (Homo sapiens) 6480464 Formaldehyde results in increased phosphorylation of and results in decreased expression of PXN protein and Formaldehyde results in increased phosphorylation of and results in increased activity of PXN protein CTD PMID:16352387 and PMID:26400731 FR900359 affects phosphorylation ISO PXN (Homo sapiens) 6480464 FR900359 affects the phosphorylation of PXN protein CTD PMID:37730182 fulvestrant multiple interactions ISO PXN (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of PXN gene CTD PMID:31601247 genistein decreases expression ISO PXN (Homo sapiens) 6480464 Genistein results in decreased expression of PXN mRNA CTD PMID:22228119 glucose increases expression EXP 6480464 Glucose results in increased expression of PXN protein modified form CTD PMID:31483951 glucose decreases expression EXP 6480464 Glucose results in decreased expression of PXN protein CTD PMID:31483951 glucose multiple interactions EXP 6480464 Eucalyptol inhibits the reaction [Glucose results in decreased expression of PXN protein] more ... CTD PMID:31483951 heparin decreases phosphorylation EXP 6480464 Heparin results in decreased phosphorylation of PXN protein CTD PMID:18674534 hydrogen peroxide multiple interactions EXP 6480464 [Hydrogen Peroxide co-treated with N-(oxo-5 more ... CTD PMID:31494107 ibuprofen decreases expression ISO Pxn (Rattus norvegicus) 6480464 Ibuprofen results in decreased expression of PXN mRNA and Ibuprofen results in decreased expression of PXN protein CTD PMID:16463375 isoflavones affects expression ISO PXN (Homo sapiens) 6480464 Isoflavones affects the expression of PXN mRNA CTD PMID:16365062 ivermectin decreases expression ISO PXN (Homo sapiens) 6480464 Ivermectin results in decreased expression of PXN protein CTD PMID:32959892 lithium chloride increases expression ISO PXN (Homo sapiens) 6480464 Lithium Chloride results in increased expression of PXN mRNA CTD PMID:23527032 lithocholic acid multiple interactions ISO PXN (Homo sapiens) 6480464 Lithocholic Acid results in decreased phosphorylation of and results in decreased activity of PXN protein CTD PMID:21224350 mercury atom affects localization ISO PXN (Homo sapiens) 6480464 Mercury affects the localization of PXN protein CTD PMID:26600472 mercury(0) affects localization ISO PXN (Homo sapiens) 6480464 Mercury affects the localization of PXN protein CTD PMID:26600472 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of PXN mRNA CTD PMID:26307267 methotrexate increases expression ISO PXN (Homo sapiens) 6480464 Methotrexate results in increased expression of PXN mRNA CTD PMID:17400583 and PMID:21678067 methoxychlor affects expression EXP 6480464 Methoxychlor affects the expression of PXN mRNA CTD PMID:20829426 mevalonic acid multiple interactions ISO Pxn (Rattus norvegicus) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [AGT protein results in increased phosphorylation of PXN protein]] CTD PMID:22306966 microcystin-LR increases expression ISO PXN (Homo sapiens) 6480464 cyanoginosin LR results in increased expression of PXN mRNA CTD PMID:27796937 microcystin-LR decreases expression ISO Pxn (Rattus norvegicus) 6480464 cyanoginosin LR results in decreased expression of PXN mRNA CTD PMID:36657700 oxotremorine M multiple interactions ISO PXN (Homo sapiens) 6480464 [oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein] more ... CTD PMID:10537051 oxotremorine M increases phosphorylation ISO PXN (Homo sapiens) 6480464 oxotremorine M results in increased phosphorylation of PXN protein CTD PMID:10537051 ozone multiple interactions ISO PXN (Homo sapiens) 6480464 [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of PXN mRNA more ... CTD PMID:32699268 and PMID:35430440 ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of PXN mRNA CTD PMID:27106289 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of PXN mRNA CTD PMID:17562736 paracetamol increases expression ISO PXN (Homo sapiens) 6480464 Acetaminophen results in increased expression of PXN mRNA CTD PMID:22230336 and PMID:26690555 pentanal increases expression ISO PXN (Homo sapiens) 6480464 pentanal results in increased expression of PXN mRNA CTD PMID:26079696 perfluorooctane-1-sulfonic acid increases phosphorylation ISO PXN (Homo sapiens) 6480464 perfluorooctane sulfonic acid results in increased phosphorylation of PXN protein CTD PMID:27572461 perfluorooctanoic acid decreases expression ISO Pxn (Rattus norvegicus) 6480464 perfluorooctanoic acid results in decreased expression of PXN mRNA CTD PMID:19162173 perfluorooctanoic acid increases phosphorylation ISO PXN (Homo sapiens) 6480464 perfluorooctanoic acid results in increased phosphorylation of PXN protein CTD PMID:27572461 phenylarsine oxide multiple interactions ISO PXN (Homo sapiens) 6480464 [oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein] and Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 phenylarsine oxide affects localization ISO PXN (Homo sapiens) 6480464 oxophenylarsine affects the localization of PXN protein CTD PMID:9546377 phenylarsine oxide increases phosphorylation ISO PXN (Homo sapiens) 6480464 oxophenylarsine results in increased phosphorylation of PXN protein CTD PMID:10537051 phenylmercury acetate increases expression ISO PXN (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of PXN mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO PXN (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PXN mRNA CTD PMID:27188386 quercetin decreases phosphorylation ISO PXN (Homo sapiens) 6480464 Quercetin results in decreased phosphorylation of PXN protein CTD PMID:35688186 reactive oxygen species multiple interactions ISO PXN (Homo sapiens) 6480464 Anethole Trithione inhibits the reaction [Reactive Oxygen Species results in increased phosphorylation of PXN protein] CTD PMID:11213483 reactive oxygen species increases phosphorylation ISO PXN (Homo sapiens) 6480464 Reactive Oxygen Species results in increased phosphorylation of PXN protein CTD PMID:11213483 resveratrol multiple interactions EXP 6480464 resveratrol inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased phosphorylation of PXN protein] CTD PMID:26621445 resveratrol multiple interactions ISO Pxn (Rattus norvegicus) 6480464 resveratrol inhibits the reaction [dinitrophenyl-human serum albumin conjugate results in increased phosphorylation of PXN protein] CTD PMID:26621445 SB 431542 multiple interactions ISO PXN (Homo sapiens) 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:37664457 silicon dioxide increases expression ISO PXN (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of PXN mRNA CTD PMID:25895662 silicon dioxide decreases expression ISO PXN (Homo sapiens) 6480464 Silicon Dioxide analog results in decreased expression of PXN mRNA CTD PMID:23806026 simvastatin decreases phosphorylation ISO Pxn (Rattus norvegicus) 6480464 Simvastatin results in decreased phosphorylation of PXN protein CTD PMID:22306966 simvastatin affects localization ISO Pxn (Rattus norvegicus) 6480464 Simvastatin affects the localization of PXN protein CTD PMID:22306966 simvastatin multiple interactions ISO Pxn (Rattus norvegicus) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [AGT protein results in increased phosphorylation of PXN protein]] and Simvastatin inhibits the reaction [AGT protein results in increased phosphorylation of and affects the localization of PXN protein] CTD PMID:22306966 sodium arsenite decreases expression ISO Pxn (Rattus norvegicus) 6480464 sodium arsenite results in decreased expression of PXN protein CTD PMID:19072884 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of PXN mRNA CTD PMID:26674514 sodium arsenite decreases phosphorylation ISO Pxn (Rattus norvegicus) 6480464 sodium arsenite results in decreased phosphorylation of PXN protein CTD PMID:15537746 Soman increases expression ISO Pxn (Rattus norvegicus) 6480464 Soman results in increased expression of PXN mRNA CTD PMID:19281266 T-2 toxin increases expression ISO PXN (Homo sapiens) 6480464 T-2 Toxin results in increased expression of PXN mRNA CTD PMID:34581912 terbinafine decreases phosphorylation ISO PXN (Homo sapiens) 6480464 terbinafine results in decreased phosphorylation of PXN protein CTD PMID:17172416 toxaphene multiple interactions ISO PXN (Homo sapiens) 6480464 CAT protein inhibits the reaction [Toxaphene results in increased degradation of PXN protein] CTD PMID:12139946 toxaphene increases degradation ISO PXN (Homo sapiens) 6480464 Toxaphene results in increased degradation of PXN protein CTD PMID:12139946 troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of PXN mRNA CTD PMID:28973697 tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate multiple interactions ISO PXN (Homo sapiens) 6480464 Atropine inhibits the reaction [[oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein]] CTD PMID:10537051 tungsten decreases expression EXP 6480464 Tungsten results in decreased expression of PXN mRNA CTD PMID:30912803 valproic acid decreases expression ISO PXN (Homo sapiens) 6480464 Valproic Acid results in decreased expression of PXN mRNA CTD PMID:23527032 valproic acid affects expression ISO PXN (Homo sapiens) 6480464 Valproic Acid affects the expression of PXN mRNA CTD PMID:25979313 valproic acid increases expression ISO PXN (Homo sapiens) 6480464 Valproic Acid results in increased expression of PXN mRNA CTD PMID:23179753 vinclozolin affects expression ISO Pxn (Rattus norvegicus) 6480464 vinclozolin affects the expression of PXN mRNA CTD PMID:23034163 vorinostat increases expression ISO PXN (Homo sapiens) 6480464 vorinostat results in increased expression of PXN mRNA and vorinostat results in increased expression of PXN protein CTD PMID:19911379 wortmannin multiple interactions ISO PXN (Homo sapiens) 6480464 [oxotremorine M co-treated with wortmannin] inhibits the reaction [oxophenylarsine results in increased phosphorylation of PXN protein] more ... CTD PMID:10537051 xanthohumol decreases expression ISO PXN (Homo sapiens) 6480464 xanthohumol results in decreased expression of PXN protein CTD PMID:23503627