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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [1, 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of UPF1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | EXP | | 6480464 | Ethinyl Estradiol affects the expression of UPF1 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UPF1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | RGD:1313946 | 6480464 | [Estradiol binds to ESR2 protein] which results in increased expression of UPF1 mRNA | CTD | PMID:20404318 | 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one | multiple interactions | ISO | RGD:1313946 | 6480464 | Metribolone promotes the reaction [NDRG1 protein binds to UPF1 protein] | CTD | PMID:17220478 | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31388691 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of UPF1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of UPF1 mRNA | CTD | PMID:17942748 | 2-methylcholine | affects expression | ISO | RGD:1313946 | 6480464 | beta-methylcholine affects the expression of UPF1 mRNA | CTD | PMID:21179406 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3, 4-methylenedioxyamphetamine results in increased expression of UPF1 mRNA | CTD | PMID:20188158 | acrylamide | decreases expression | ISO | RGD:1589127 | 6480464 | Acrylamide results in decreased expression of UPF1 mRNA | CTD | PMID:28959563 | afimoxifene | increases expression | ISO | RGD:1313946 | 6480464 | afimoxifene results in increased expression of UPF1 mRNA | CTD | PMID:16849584 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of UPF1 mRNA | CTD | PMID:19770486 | amlexanox | affects localization | ISO | RGD:1313946 | 6480464 | amlexanox affects the localization of UPF1 protein | CTD | PMID:28743738 | arsane | affects methylation | ISO | RGD:1313946 | 6480464 | Arsenic affects the methylation of UPF1 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | RGD:1313946 | 6480464 | Arsenic affects the methylation of UPF1 gene | CTD | PMID:25304211 | benzo[a]pyrene | multiple interactions | EXP | | 6480464 | AHR protein affects the reaction [Benzoapyrene affects the expression of UPF1 mRNA], Benzoapyrene promotes the reaction [AHR protein binds to UPF1 promoter] | CTD | PMID:19654925, PMID:22228805 | benzo[a]pyrene | increases methylation | ISO | RGD:1313946 | 6480464 | Benzoapyrene results in increased methylation of UPF1 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzoapyrene results in increased expression of UPF1 mRNA | CTD | PMID:19770486, PMID:22228805 | bisphenol A | increases expression | ISO | RGD:1589127 | 6480464 | bisphenol A results in increased expression of UPF1 mRNA | CTD | PMID:25181051 | camptothecin | decreases response to substance | ISO | RGD:1313946 | 6480464 | UPF1 mRNA results in decreased susceptibility to Camptothecin | CTD | PMID:25269479 | carmustine | decreases expression | ISO | RGD:1313946 | 6480464 | Carmustine results in decreased expression of UPF1 mRNA | CTD | PMID:15980968 | choline | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of UPF1 gene | CTD | PMID:20938992 | cyclosporin A | decreases expression | EXP | | 6480464 | Cyclosporine results in decreased expression of UPF1 mRNA | CTD | PMID:19770486 | cytochalasin D | affects localization | ISO | RGD:1313946 | 6480464 | Cytochalasin D affects the localization of UPF1 protein | CTD | PMID:28743738 | cytochalasin D | multiple interactions | ISO | RGD:1313946 | 6480464 | Cytochalasin D inhibits the reaction [UPF1 protein binds to ACTG1 protein] | CTD | PMID:28743738 | diazinon | increases methylation | ISO | RGD:1313946 | 6480464 | Diazinon results in increased methylation of UPF1 gene | CTD | PMID:22964155 | dicrotophos | increases expression | ISO | RGD:1313946 | 6480464 | dicrotophos results in increased expression of UPF1 mRNA | CTD | PMID:28302478 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of UPF1 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | EXP | | 6480464 | [1 more ... | CTD | PMID:20938992, PMID:22206623 | geneticin | affects localization | ISO | RGD:1313946 | 6480464 | antibiotic G 418 affects the localization of UPF1 protein | CTD | PMID:28743738 | jaspamide | multiple interactions | ISO | RGD:1313946 | 6480464 | jasplakinolide inhibits the reaction [UPF1 protein binds to ACTG1 protein] | CTD | PMID:28743738 | jaspamide | affects localization | ISO | RGD:1313946 | 6480464 | jasplakinolide affects the localization of UPF1 protein | CTD | PMID:28743738 | L-methionine | multiple interactions | EXP | | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of UPF1 gene | CTD | PMID:20938992 | methyl methanesulfonate | increases expression | ISO | RGD:1313946 | 6480464 | Methyl Methanesulfonate results in increased expression of UPF1 mRNA | CTD | PMID:23649840 | mono(2-ethylhexyl) phthalate | decreases expression | EXP | | 6480464 | mono-2-ethylhexylphthalate results in decreased expression of UPF1 mRNA | CTD | PMID:22401849 | N-ethyl-N-nitrosourea | increases mutagenesis | EXP | | 6480464 | Ethylnitrosourea results in increased mutagenesis of UPF1 intron | CTD | PMID:27776689 | perfluorooctanoic acid | decreases expression | ISO | RGD:1313946 | 6480464 | perfluorooctanoic acid results in decreased expression of UPF1 protein | CTD | PMID:26879310 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of UPF1 mRNA | CTD | PMID:18445702 | raloxifene | affects expression | ISO | RGD:1313946 | 6480464 | Raloxifene Hydrochloride affects the expression of UPF1 mRNA | CTD | PMID:14699072 | raloxifene | multiple interactions | ISO | RGD:1313946 | 6480464 | [Raloxifene Hydrochloride co-treated with ESR2 protein] results in decreased expression of UPF1 mRNA | CTD | PMID:19059307 | rotenone | decreases expression | ISO | RGD:1313946 | 6480464 | Rotenone results in decreased expression of UPF1 mRNA | CTD | PMID:29955902 | sodium arsenite | affects expression | ISO | RGD:1313946 | 6480464 | sodium arsenite affects the expression of UPF1 mRNA | CTD | PMID:29319823 | sodium fluoride | increases expression | EXP | | 6480464 | Sodium Fluoride results in increased expression of UPF1 mRNA | CTD | PMID:27862939 | tamoxifen | affects expression | ISO | RGD:1313946 | 6480464 | Tamoxifen affects the expression of UPF1 mRNA | CTD | PMID:14699072 | tamoxifen | multiple interactions | ISO | RGD:1313946 | 6480464 | [Tamoxifen co-treated with ESR2 protein] results in decreased expression of UPF1 mRNA | CTD | PMID:19059307 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of UPF1 mRNA | CTD | PMID:31919559 | thimerosal | decreases expression | ISO | RGD:1313946 | 6480464 | Thimerosal results in decreased expression of UPF1 mRNA | CTD | PMID:27188386 | torcetrapib | increases expression | ISO | RGD:1313946 | 6480464 | torcetrapib results in increased expression of UPF1 mRNA | CTD | PMID:23228038 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of UPF1 mRNA | CTD | PMID:28973697 | tungsten | decreases expression | EXP | | 6480464 | Tungsten results in decreased expression of UPF1 mRNA | CTD | PMID:30912803 | urethane | increases expression | ISO | RGD:1313946 | 6480464 | Urethane results in increased expression of UPF1 mRNA | CTD | PMID:28818685 | valproic acid | affects expression | ISO | RGD:1313946 | 6480464 | Valproic Acid affects the expression of UPF1 mRNA | CTD | PMID:25979313 | valproic acid | decreases methylation | ISO | RGD:1313946 | 6480464 | Valproic Acid results in decreased methylation of UPF1 gene | CTD | PMID:29154799 | vinclozolin | decreases expression | ISO | RGD:1589127 | 6480464 | vinclozolin results in decreased expression of UPF1 mRNA | CTD | PMID:23034163 | zinc atom | multiple interactions | ISO | RGD:1313946 | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of UPF1 mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | RGD:1313946 | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of UPF1 mRNA | CTD | PMID:18593933 | |