PRXL2C (peroxiredoxin like 2C) - Rat Genome Database

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Gene: PRXL2C (peroxiredoxin like 2C) Homo sapiens
Analyze
Symbol: PRXL2C
Name: peroxiredoxin like 2C
RGD ID: 1313944
HGNC Page HGNC
Description: Predicted to enable antioxidant activity. Involved in positive regulation of ERK1 and ERK2 cascade and positive regulation of glycolytic process; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AAED1; AhpC/TSA antioxidant enzyme domain containing 1; ahpC/TSA antioxidant enzyme domain-containing protein 1; C9orf21; hypothetical protein LOC195827; peroxiredoxin-like 2C; thioredoxin-like protein AAED1; UPF0308 protein C9orf21
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: PRXL2CP1  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl996,639,577 - 96,655,317 (-)EnsemblGRCh38hg38GRCh38
GRCh38996,639,577 - 96,655,331 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37999,401,859 - 99,417,599 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36998,443,354 - 98,457,420 (-)NCBINCBI36hg18NCBI36
Celera969,845,106 - 69,859,172 (-)NCBI
Cytogenetic Map9q22.33NCBI
HuRef969,014,734 - 69,028,253 (-)NCBIHuRef
CHM1_1999,550,355 - 99,564,421 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12234665   PMID:12477932   PMID:14710190   PMID:15164053   PMID:16341674   PMID:19322201   PMID:21873635   PMID:26186194   PMID:28514442   PMID:29901208  


Genomics

Comparative Map Data
PRXL2C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl996,639,577 - 96,655,317 (-)EnsemblGRCh38hg38GRCh38
GRCh38996,639,577 - 96,655,331 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37999,401,859 - 99,417,599 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36998,443,354 - 98,457,420 (-)NCBINCBI36hg18NCBI36
Celera969,845,106 - 69,859,172 (-)NCBI
Cytogenetic Map9q22.33NCBI
HuRef969,014,734 - 69,028,253 (-)NCBIHuRef
CHM1_1999,550,355 - 99,564,421 (-)NCBICHM1_1
Prxl2c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391364,437,612 - 64,460,524 (-)NCBIGRCm39mm39
GRCm39 Ensembl1364,423,094 - 64,460,524 (-)Ensembl
GRCm381364,289,798 - 64,312,710 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1364,275,280 - 64,312,710 (-)EnsemblGRCm38mm10GRCm38
MGSCv371364,393,144 - 64,414,018 (-)NCBIGRCm37mm9NCBIm37
MGSCv361364,301,606 - 64,326,737 (-)NCBImm8
Celera1365,956,327 - 65,976,100 (-)NCBICelera
Cytogenetic Map13B3NCBI
Prxl2c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.217812,199 - 844,075 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl17812,213 - 844,075 (+)Ensembl
Rnor_6.0171,798,224 - 1,830,011 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl171,798,388 - 1,830,001 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0171,787,497 - 1,819,908 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4176,336,052 - 6,370,548 (+)NCBIRGSC3.4rn4RGSC3.4
Celera171,672,532 - 1,704,457 (-)NCBICelera
Cytogenetic Map17p14NCBI
PRXL2C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1995,857,770 - 95,889,532 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0967,737,639 - 67,751,691 (-)NCBIMhudiblu_PPA_v0panPan3
PRXL2C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1170,199,278 - 70,209,026 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl170,199,357 - 70,208,534 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha170,962,502 - 70,972,184 (+)NCBI
ROS_Cfam_1.0170,487,981 - 70,508,109 (+)NCBI
UMICH_Zoey_3.1170,312,093 - 70,321,759 (+)NCBI
UNSW_CanFamBas_1.0170,074,911 - 70,084,654 (+)NCBI
UU_Cfam_GSD_1.0170,786,250 - 70,795,855 (+)NCBI
PRXL2C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1025,428,164 - 25,446,185 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11025,428,129 - 25,444,609 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21076,570,687 - 76,584,991 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PRXL2C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.112106,486,772 - 106,500,124 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl12106,486,811 - 106,499,618 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603894,883,326 - 94,897,531 (+)NCBIVero_WHO_p1.0
Prxl2c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475317,901,281 - 17,922,146 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D12S1672  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh3712112,033,960 - 112,034,238UniSTSGRCh37
Build 3612110,518,343 - 110,518,621RGDNCBI36
Celera12111,660,337 - 111,660,615RGD
Cytogenetic Map12q24.1UniSTS
Cytogenetic Map9q22.32UniSTS
HuRef969,015,704 - 69,016,094UniSTS
HuRef12109,048,153 - 109,048,431UniSTS
Marshfield Genetic Map12119.55UniSTS
Marshfield Genetic Map12119.55RGD
Genethon Genetic Map12120.5UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2952
Count of miRNA genes:702
Interacting mature miRNAs:785
Transcripts:ENST00000375234, ENST00000411939, ENST00000446045, ENST00000464512
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1449 1446 740 55 572 48 2494 1133 737 172 677 1471 22 1 1175 1615 4 1
Low 990 1500 986 569 1320 417 1863 1064 2997 245 783 142 152 29 1173 2 1
Below cutoff 45 52 2

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000375234   ⟹   ENSP00000364382
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl996,639,577 - 96,655,317 (-)Ensembl
RefSeq Acc Id: ENST00000411939   ⟹   ENSP00000412378
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl996,639,577 - 96,654,748 (-)Ensembl
RefSeq Acc Id: ENST00000446045   ⟹   ENSP00000398933
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl996,639,577 - 96,655,303 (-)Ensembl
RefSeq Acc Id: ENST00000464512
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl996,645,990 - 96,654,972 (-)Ensembl
RefSeq Acc Id: NM_153698   ⟹   NP_714542
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38996,639,577 - 96,655,317 (-)NCBI
GRCh37999,403,109 - 99,417,603 (-)NCBI
Build 36998,443,354 - 98,457,420 (-)NCBI Archive
Celera969,845,106 - 69,859,172 (-)RGD
HuRef969,014,734 - 69,028,253 (-)ENTREZGENE
CHM1_1999,550,355 - 99,564,421 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005251783   ⟹   XP_005251840
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38996,641,251 - 96,655,312 (-)NCBI
GRCh37999,403,109 - 99,417,603 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005251784   ⟹   XP_005251841
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38996,641,251 - 96,655,331 (-)NCBI
GRCh37999,403,109 - 99,417,603 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_714542   ⟸   NM_153698
- UniProtKB: Q7RTV5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_005251840   ⟸   XM_005251783
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_005251841   ⟸   XM_005251784
- Peptide Label: isoform X2
- UniProtKB: B7ZKK1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000412378   ⟸   ENST00000411939
RefSeq Acc Id: ENSP00000364382   ⟸   ENST00000375234
RefSeq Acc Id: ENSP00000398933   ⟸   ENST00000446045

Promoters
RGD ID:7215583
Promoter ID:EPDNEW_H13538
Type:initiation region
Name:AAED1_1
Description:AhpC/TSA antioxidant enzyme domain containing 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38996,655,317 - 96,655,377EPDNEW
RGD ID:6807587
Promoter ID:HG_KWN:64203
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000375233,   OTTHUMT00000053272,   OTTHUMT00000053273,   OTTHUMT00000053274,   OTTHUMT00000053275
Position:
Human AssemblyChrPosition (strand)Source
Build 36998,456,816 - 98,457,667 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain See cases [RCV000050348] Chr9:193412..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9q22.31-22.33(chr9:91596533-97018746)x1 copy number loss See cases [RCV000052916] Chr9:91596533..97018746 [GRCh38]
Chr9:94358815..99781028 [GRCh37]
Chr9:93398636..98820849 [NCBI36]
Chr9:9q22.31-22.33
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124532)x3 copy number gain See cases [RCV000053745] Chr9:193412..138124532 [GRCh38]
Chr9:204193..141018984 [GRCh37]
Chr9:194193..140138805 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138114463)x3 copy number gain See cases [RCV000053746] Chr9:193412..138114463 [GRCh38]
Chr9:214367..141008915 [GRCh37]
Chr9:204367..140128736 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000053748]|See cases [RCV000053748] Chr9:193412..138179445 [GRCh38]
Chr9:266045..141073897 [GRCh37]
Chr9:256045..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9q22.31-22.33(chr9:92561720-98122580)x3 copy number gain See cases [RCV000053773] Chr9:92561720..98122580 [GRCh38]
Chr9:95324002..100884862 [GRCh37]
Chr9:94363823..99924683 [NCBI36]
Chr9:9q22.31-22.33
pathogenic
GRCh38/hg38 9q22.1-32(chr9:88522292-113687796)x3 copy number gain See cases [RCV000053752] Chr9:88522292..113687796 [GRCh38]
Chr9:91137207..116450076 [GRCh37]
Chr9:90327027..115489897 [NCBI36]
Chr9:9q22.1-32
pathogenic
GRCh38/hg38 9q22.32-31.2(chr9:94184266-106730550)x3 copy number gain See cases [RCV000053774] Chr9:94184266..106730550 [GRCh38]
Chr9:96946548..109492831 [GRCh37]
Chr9:95986369..108532652 [NCBI36]
Chr9:9q22.32-31.2
pathogenic
Single allele deletion Intellectual disability [RCV001293373] Chr9:97834573..107199088 [GRCh37]
Chr9:9q22.32-31.1
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:204193-138179445) copy number gain See cases [RCV000133791] Chr9:204193..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9q22.32-31.3(chr9:95061030-108695569)x1 copy number loss See cases [RCV000134375] Chr9:95061030..108695569 [GRCh38]
Chr9:97823312..111457849 [GRCh37]
Chr9:96863133..110497670 [NCBI36]
Chr9:9q22.32-31.3
pathogenic
GRCh38/hg38 9q22.32-22.33(chr9:94713892-98121186)x1 copy number loss See cases [RCV000135303] Chr9:94713892..98121186 [GRCh38]
Chr9:97476174..100883468 [GRCh37]
Chr9:96515995..99923289 [NCBI36]
Chr9:9q22.32-22.33
pathogenic
GRCh38/hg38 9q21.11-31.2(chr9:68420430-106579493)x3 copy number gain See cases [RCV000136788] Chr9:68420430..106579493 [GRCh38]
Chr9:71130848..109341774 [GRCh37]
Chr9:70225166..108381595 [NCBI36]
Chr9:9q21.11-31.2
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138124524)x3 copy number gain See cases [RCV000138783] Chr9:193412..138124524 [GRCh38]
Chr9:204090..141018976 [GRCh37]
Chr9:194090..140138797 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p11.2-q34.3(chr9:193412-138159073)x3 copy number gain See cases [RCV000139207] Chr9:193412..138159073 [GRCh38]
Chr9:68420641..141053525 [GRCh37]
Chr9:67910461..140173346 [NCBI36]
Chr9:9p11.2-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138159073)x3 copy number gain See cases [RCV000138962] Chr9:193412..138159073 [GRCh38]
Chr9:204104..141053525 [GRCh37]
Chr9:194104..140173346 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic|conflicting data from submitters
GRCh38/hg38 9q21.12-31.3(chr9:69627642-111454304)x3 copy number gain See cases [RCV000139789] Chr9:69627642..111454304 [GRCh38]
Chr9:72242558..114216584 [GRCh37]
Chr9:71432378..113256405 [NCBI36]
Chr9:9q21.12-31.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:203861-138125937)x3 copy number gain See cases [RCV000141876] Chr9:203861..138125937 [GRCh38]
Chr9:203861..141020389 [GRCh37]
Chr9:193861..140140210 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:203862-138125937)x3 copy number gain See cases [RCV000143476] Chr9:203862..138125937 [GRCh38]
Chr9:203862..141020389 [GRCh37]
Chr9:193862..140140210 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh38/hg38 9p24.3-q34.3(chr9:193412-138179445)x3 copy number gain See cases [RCV000148113] Chr9:193412..138179445 [GRCh38]
Chr9:204193..141073897 [GRCh37]
Chr9:194193..140193718 [NCBI36]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:163131-141122114)x3 copy number gain See cases [RCV000240081] Chr9:163131..141122114 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9q22.33(chr9:99302837-99576623)x1 copy number loss See cases [RCV000511320] Chr9:99302837..99576623 [GRCh37]
Chr9:9q22.33
likely benign
GRCh37/hg19 9p24.3-q34.3(chr9:62525-141006407) copy number gain See cases [RCV000449375] Chr9:62525..141006407 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203861-141020389)x3 copy number gain See cases [RCV000447207] Chr9:203861..141020389 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9q22.32-22.33(chr9:97355862-99805480)x1 copy number loss See cases [RCV000445766] Chr9:97355862..99805480 [GRCh37]
Chr9:9q22.32-22.33
pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203864-141020389)x3 copy number gain See cases [RCV000448978] Chr9:203864..141020389 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9q22.32-31.1(chr9:97553176-102919383)x3 copy number gain See cases [RCV000510672] Chr9:97553176..102919383 [GRCh37]
Chr9:9q22.32-31.1
likely pathogenic
GRCh37/hg19 9q22.32-22.33(chr9:96732332-100175689)x1 copy number loss See cases [RCV000510346] Chr9:96732332..100175689 [GRCh37]
Chr9:9q22.32-22.33
pathogenic
GRCh37/hg19 9q21.11-34.3(chr9:71069743-140999928) copy number gain Global developmental delay [RCV000626548] Chr9:71069743..140999928 [GRCh37]
Chr9:9q21.11-34.3
likely pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203862-141020389) copy number gain See cases [RCV000512392] Chr9:203862..141020389 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141122247)x3 copy number gain not provided [RCV000748055] Chr9:10590..141122247 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141107672)x3 copy number gain not provided [RCV000748053] Chr9:10590..141107672 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:46587-141066491)x3 copy number gain not provided [RCV000748063] Chr9:46587..141066491 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:10590-141114095)x2 copy number gain not provided [RCV000748054] Chr9:10590..141114095 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9p24.3-q34.3(chr9:203861-141020388)x3 copy number gain not provided [RCV000845900] Chr9:203861..141020388 [GRCh37]
Chr9:9p24.3-q34.3
pathogenic
GRCh37/hg19 9q22.32-22.33(chr9:98849008-99405481)x1 copy number loss not provided [RCV000849563] Chr9:98849008..99405481 [GRCh37]
Chr9:9q22.32-22.33
uncertain significance
GRCh37/hg19 9q21.11-34.3(chr9:71416475-141020389)x3 copy number gain not provided [RCV000847808] Chr9:71416475..141020389 [GRCh37]
Chr9:9q21.11-34.3
pathogenic
GRCh37/hg19 9q22.31-31.2(chr9:96126075-108535272)x1 copy number loss See cases [RCV001194520] Chr9:96126075..108535272 [GRCh37]
Chr9:9q22.31-31.2
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:16881 AgrOrtholog
COSMIC PRXL2C COSMIC
Ensembl Genes ENSG00000158122 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000364382 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000398933 ENTREZGENE, UniProtKB/TrEMBL
  ENSP00000412378 UniProtKB/TrEMBL
Ensembl Transcript ENST00000375234 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000411939 UniProtKB/TrEMBL
  ENST00000446045 ENTREZGENE, UniProtKB/TrEMBL
GTEx ENSG00000158122 GTEx
HGNC ID HGNC:16881 ENTREZGENE
Human Proteome Map PRXL2C Human Proteome Map
InterPro PXL2A/B/C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Thioredoxin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:195827 UniProtKB/Swiss-Prot
NCBI Gene 195827 ENTREZGENE
PANTHER PTHR28630 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam AhpC-TSA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA38190 PharmGKB
Superfamily-SCOP SSF52833 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B7ZKK1 ENTREZGENE, UniProtKB/TrEMBL
  H0Y5J5_HUMAN UniProtKB/TrEMBL
  H0Y7F1_HUMAN UniProtKB/TrEMBL
  PXL2C_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary B2RMW4 UniProtKB/Swiss-Prot
  Q5JU02 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-07-24 PRXL2C  peroxiredoxin like 2C  AAED1  AhpC/TSA antioxidant enzyme domain containing 1  Symbol and/or name change 5135510 APPROVED
2012-03-13 AAED1  AhpC/TSA antioxidant enzyme domain containing 1  C9orf21  chromosome 9 open reading frame 21  Symbol and/or name change 5135510 APPROVED