Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ZFP143 mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZNF143 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of ZFP143 mRNA | CTD | PMID:25975270 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ZFP143 mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 6-propyl-2-thiouracil | decreases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of ZFP143 mRNA | CTD | PMID:30047161 | acrylamide | increases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of ZNF143 mRNA | CTD | PMID:32763439 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of ZFP143 mRNA | CTD | PMID:19770486 | aflatoxin B1 | increases methylation | ISO | ZNF143 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of ZNF143 gene | CTD | PMID:27153756 | Aflatoxin B2 alpha | increases methylation | ISO | ZNF143 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of ZNF143 intron | CTD | PMID:30157460 | all-trans-retinoic acid | increases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ZNF143 mRNA | CTD | PMID:33167477 | amitrole | decreases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of ZFP143 mRNA | CTD | PMID:30047161 | arsane | affects methylation | ISO | ZNF143 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZNF143 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | ZNF143 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ZNF143 gene | CTD | PMID:25304211 | atrazine | decreases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Atrazine results in decreased expression of ZNF143 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ZFP143 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | ZNF143 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ZNF143 3' UTR and Benzo(a)pyrene affects the methylation of ZNF143 intron | CTD | PMID:27901495 and PMID:30157460 | benzo[e]pyrene | increases methylation | ISO | ZNF143 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of ZNF143 intron | CTD | PMID:30157460 | bisphenol A | increases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of ZNF143 mRNA | CTD | PMID:25181051 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ZFP143 mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ZNF143 mRNA | CTD | PMID:34947998 | bisphenol A | decreases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of ZNF143 mRNA | CTD | PMID:29275510 | bisphenol A | increases methylation | ISO | Zfp143 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of ZFP143 gene | CTD | PMID:28505145 | butanal | increases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of ZNF143 mRNA | CTD | PMID:26079696 | cisplatin | multiple interactions | ISO | ZNF143 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of ZNF143 mRNA | CTD | PMID:27392435 | copper atom | multiple interactions | ISO | ZNF143 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of ZNF143 mRNA | CTD | PMID:24690739 | copper(0) | multiple interactions | ISO | ZNF143 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of ZNF143 mRNA | CTD | PMID:24690739 | copper(II) sulfate | increases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ZNF143 mRNA | CTD | PMID:19549813 | crocidolite asbestos | increases expression | EXP | | 6480464 | Asbestos and Crocidolite results in increased expression of ZFP143 mRNA | CTD | PMID:19446018 | CU-O LINKAGE | increases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | cupric oxide results in increased expression of ZNF143 mRNA | CTD | PMID:22077320 | cyclosporin A | increases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of ZNF143 mRNA | CTD | PMID:20106945 and PMID:25562108 | dibenziodolium | multiple interactions | ISO | ZNF143 (Homo sapiens) | 6480464 | diphenyleneiodonium inhibits the reaction [IGF1 protein results in increased expression of ZNF143 protein] | CTD | PMID:20733350 | dicrotophos | decreases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of ZNF143 mRNA | CTD | PMID:28302478 | disulfiram | multiple interactions | ISO | ZNF143 (Homo sapiens) | 6480464 | [Disulfiram binds to Copper] which results in decreased expression of ZNF143 mRNA | CTD | PMID:24690739 | doxorubicin | decreases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of ZNF143 mRNA | CTD | PMID:29803840 | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of ZFP143 mRNA | CTD | PMID:35436446 | gentamycin | increases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of ZFP143 mRNA | CTD | PMID:33387578 | methapyrilene | increases methylation | ISO | ZNF143 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of ZNF143 intron | CTD | PMID:30157460 | methimazole | decreases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of ZFP143 mRNA | CTD | PMID:30047161 | monodansylcadaverine | multiple interactions | ISO | ZNF143 (Homo sapiens) | 6480464 | monodansylcadaverine inhibits the reaction [[IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein] | CTD | PMID:20733350 | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of ZFP143 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | Acetaminophen results in decreased expression of ZFP143 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ZNF143 mRNA | CTD | PMID:29067470 | pregnenolone 16alpha-carbonitrile | decreases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in decreased expression of ZFP143 mRNA | CTD | PMID:30047161 | reactive oxygen species | multiple interactions | ISO | ZNF143 (Homo sapiens) | 6480464 | [IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein and monodansylcadaverine inhibits the reaction [[IGF1 protein results in increased abundance of Reactive Oxygen Species] which results in increased expression of ZNF143 protein] | CTD | PMID:20733350 | resveratrol | multiple interactions | ISO | ZNF143 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of ZNF143 mRNA | CTD | PMID:23557933 | rotenone | increases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | Rotenone results in increased expression of ZFP143 mRNA | CTD | PMID:28374803 | silicon dioxide | increases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of ZNF143 mRNA and Silicon Dioxide results in increased expression of ZNF143 mRNA | CTD | PMID:23806026 and PMID:25351596 | thioacetamide | increases expression | ISO | Zfp143 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of ZFP143 mRNA | CTD | PMID:34492290 | titanium dioxide | increases expression | EXP | | 6480464 | titanium dioxide results in increased expression of ZFP143 mRNA | CTD | PMID:23409001 | Triptolide | increases expression | EXP | | 6480464 | triptolide results in increased expression of ZFP143 mRNA | CTD | PMID:32835833 | troglitazone | decreases expression | EXP | | 6480464 | troglitazone results in decreased expression of ZNF143 mRNA | CTD | PMID:28973697 | urethane | increases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Urethane results in increased expression of ZNF143 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | ZNF143 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ZNF143 mRNA | CTD | PMID:23179753 | vinclozolin | increases methylation | ISO | Zfp143 (Rattus norvegicus) | 6480464 | vinclozolin results in increased methylation of ZFP143 gene | CTD | PMID:31682807 | wortmannin | multiple interactions | ISO | ZNF143 (Homo sapiens) | 6480464 | wortmannin inhibits the reaction [IGF1 protein results in increased expression of ZNF143 protein] | CTD | PMID:20733350 | |