Ccnq (cyclin Q) - Rat Genome Database
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Gene: Ccnq (cyclin Q) Mus musculus
Analyze
Symbol: Ccnq
Name: cyclin Q
RGD ID: 1313805
MGI Page MGI
Description: Is expressed in central nervous system; embryo; retina; retina inner nuclear layer; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in syndactyly-telecanthus-anogenital and renal malformations syndrome. Orthologous to several human genes including CCNQ (cyclin Q); INTERACTS WITH 1,2-dimethylhydrazine; 3,4-methylenedioxymethamphetamine; ethanol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810009O10Rik; CDK10-activating cyclin; cyclin M; cyclin-M; cyclin-Q; cyclin-related protein FAM58A; cyclin-related protein FAM58B; Fam58; Fam58a; Fam58b; family with sequence similarity 58, member B; RP23-404C20.1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm16530   Gm8342   Gm9730   Gm9731  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,641,332 - 78,642,555 (-)NCBIGRCm39mm39
GRCm39 Ensembl1178,641,332 - 78,642,555 (-)Ensembl
GRCm381178,750,506 - 78,751,729 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,750,506 - 78,751,729 (-)EnsemblGRCm38mm10GRCm38
MGSCv371178,564,008 - 78,565,231 (-)NCBIGRCm37mm9NCBIm37
MGSCv361178,566,701 - 78,567,924 (-)NCBImm8
Celera1188,383,125 - 88,384,342 (-)NCBICelera
Cytogenetic Map11B5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleus  (IBA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:12819135   PMID:15226823   PMID:15782199   PMID:16141072   PMID:16141073   PMID:21873635   PMID:24218572  


Genomics

Comparative Map Data
Ccnq
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391178,641,332 - 78,642,555 (-)NCBIGRCm39mm39
GRCm39 Ensembl1178,641,332 - 78,642,555 (-)Ensembl
GRCm381178,750,506 - 78,751,729 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1178,750,506 - 78,751,729 (-)EnsemblGRCm38mm10GRCm38
MGSCv371178,564,008 - 78,565,231 (-)NCBIGRCm37mm9NCBIm37
MGSCv361178,566,701 - 78,567,924 (-)NCBImm8
Celera1188,383,125 - 88,384,342 (-)NCBICelera
Cytogenetic Map11B5NCBI
CCNQ
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblX153,587,925 - 153,600,045 (-)EnsemblGRCh38hg38GRCh38
GRCh38X153,587,925 - 153,599,165 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X152,853,383 - 152,864,595 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X152,506,577 - 152,517,775 (-)NCBINCBI36hg18NCBI36
CeleraX153,087,076 - 153,098,328 (-)NCBI
Cytogenetic MapXq28NCBI
HuRefX141,511,974 - 141,519,982 (-)NCBIHuRef
CHM1_1X152,727,894 - 152,739,153 (-)NCBICHM1_1
Ccnq
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21063,646,532 - 63,647,695 (-)NCBI
Rnor_6.0 Ensembl1066,019,520 - 66,020,682 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01066,019,519 - 66,020,682 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01065,623,147 - 65,624,310 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41064,864,942 - 64,866,105 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11064,878,565 - 64,879,728 (-)NCBI
Celera1062,622,471 - 62,623,635 (-)NCBICelera
Cytogenetic Map10q25NCBI
Ccnq
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955580336,681 - 349,435 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955580336,681 - 349,435 (-)NCBIChiLan1.0ChiLan1.0
CCNQ
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1X153,024,766 - 153,039,312 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v0X143,138,574 - 143,149,824 (-)NCBIMhudiblu_PPA_v0panPan3
CCNQ
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 EnsemblX121,409,625 - 121,418,395 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1X121,409,169 - 121,418,666 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ccnq
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936809471,619 - 482,296 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCNQ
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX124,361,002 - 124,369,868 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X124,361,003 - 124,370,072 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X141,924,436 - 141,933,327 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CCNQ
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X128,018,651 - 128,030,122 (-)NCBI
ChlSab1.1 EnsemblX128,019,090 - 128,030,083 (-)Ensembl
Ccnq
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624946311,291 - 322,546 (-)NCBI

Position Markers
RH142728  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37828,407,293 - 28,407,525UniSTSGRCm37
MGSCv371178,564,155 - 78,564,395UniSTSGRCm37
Celera1188,383,272 - 88,383,512UniSTS
Celera839,737,212 - 39,737,443UniSTS
Celera828,787,161 - 28,787,393UniSTS
Celera839,747,767 - 39,747,999UniSTS
Celera839,726,657 - 39,726,889UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13208559Wght10_mweight 10 (mouse)11400000089000000Mouse
13208558Lgth12_mbody length 12 (mouse)11400000095000000Mouse
1300905Scc6_mcolon tumor susceptibility 6 (mouse)Not determined11693027789128908Mouse
1357859Lvrq7_mliver weight QTL 7 (mouse)Not determined1112318637118131898Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112318637118131898Mouse
4141894Nidd6k_mNidd6 on KK-A (mouse)Not determined1917420497007000Mouse
10412246Dfs2_mdental fluorosis suseptibility 2 (mouse)Not determined112185736495990405Mouse
13208569Bmiq10_mbody mass index QTL 10 (mouse)113600000085000000Mouse
1301328Mol4_mmodifier of LPS-response 4 (mouse)Not determined113639175083590530Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44739211113167183Mouse
4141000Nidd3_mnon-insulin-dependent diabetes mellitus 3 (mouse)Not determined4515120179151308Mouse
1302021Nidd1n_mnon-insulin-dependent diabetes mellitus 1 in NSY (mouse)Not determined114527504680087498Mouse
1357878Mastr_mmodifier of astrocytoma (mouse)Not determined114581775489927907Mouse
1300765Bbaa4_mB.burgdorferi-associated arthritis 4 (mouse)Not determined114629434180294436Mouse
1301988Bmd11_mbone mineral density 11 (mouse)Not determined114642858180428696Mouse
1301830Ssta4_msusceptibility to Salmonella typhimurium antigens 4 (mouse)Not determined115018736584187585Mouse
13524840Ppiq9a_mprepulse inhibition QTL 9a (mouse)115260355986603559Mouse
1300774Pgia7_mproteoglycan induced arthritis 7 (mouse)Not determined115349976287499911Mouse
4141830Pregq1_mpregnancy QTL 1 (mouse)Not determined115423592683842826Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156973201114267131Mouse
1300664Etohcta9_methanol conditioned taste aversion 9 (mouse)Not determined115786383491863932Mouse
1300924Ity2_mimmunity to S. typhimurium 2 (mouse)Not determined15861720487804412Mouse
4141982Skts-fp2_mskin tumor susceptibility in FVB and PWK 2 (mouse)Not determined5882844085175703Mouse
1301987Pid3_mprior incubation determinant 3 (mouse)Not determined116179599488808902Mouse
1301319Dautb4_mdopamine uptake transporter binding 4 (mouse)Not determined116226517996265327Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162700000109500000Mouse
1301999Lmr15_mleishmaniasis resistance 15 (mouse)Not determined116342858181939647Mouse
10044004Stzid3_mstreptozotocin induced diabetes susceptibility 3 (mouse)Not determined116342858194173092Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116493951098939647Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116493951098939647Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116493951098939647Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166842594100842826Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166842594100842826Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66842594100842826Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166842594100842826Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166842594100842826Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166842594100842826Mouse
4142316Ity2b_mimmunity to S. typhimurium 2b (mouse)Not determined116718736579923086Mouse
27226783Tibl5_mtibia length 5, 5 week (mouse)1168300000102000000Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170800372104800540Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170800372104800540Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170800372104800540Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170800372104800540Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172128823106128908Mouse
1301078Alcp2_malcohol preference locus 2 (mouse)Not determined117231897084840636Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172835299106835463Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172927789106927907Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172927789106927907Mouse
12903994Opfaq3_mopen field activity QTL 3 (mouse)117384671582178599Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177172953111173092Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177546357111546496Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177546357111546496Mouse
4141365Ltxs3_mlethal factor toxin susceptibility 3 (mouse)Not determined117768304780855532Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117768304799486994Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177880152111880273Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:159
Count of miRNA genes:139
Interacting mature miRNAs:149
Transcripts:ENSMUST00000059468
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000059468   ⟹   ENSMUSP00000050658
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1178,750,506 - 78,751,729 (-)Ensembl
RefSeq Acc Id: NM_197989   ⟹   NP_932106
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391178,641,332 - 78,642,555 (-)NCBI
GRCm381178,750,506 - 78,751,729 (-)ENTREZGENE
MGSCv371178,564,008 - 78,565,231 (-)RGD
Celera1188,383,125 - 88,384,342 (-)RGD
cM Map11 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_932106 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH27022 (Get FASTA)   NCBI Sequence Viewer  
  AAS20613 (Get FASTA)   NCBI Sequence Viewer  
  EDL15593 (Get FASTA)   NCBI Sequence Viewer  
  Q8QZR8 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_932106   ⟸   NM_197989
- UniProtKB: Q8QZR8 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000050658   ⟸   ENSMUST00000059468

Promoters
RGD ID:6820860
Promoter ID:MM_KWN:8734
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_197989
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361178,564,964 - 78,565,464 (-)MPROMDB
RGD ID:8675746
Promoter ID:EPDNEW_M15904
Type:multiple initiation site
Name:Fam58b_1
Description:Mus musculus family with sequence similarity 58, member B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381178,751,682 - 78,751,742EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1916359 AgrOrtholog
Ensembl Genes ENSMUSG00000049489 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000050658 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000059468 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Cyclin-like UniProtKB/Swiss-Prot
  Cyclin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin-Q UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin/Ssn8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Cyclin_N UniProtKB/Swiss-Prot
KEGG Report mmu:69109 UniProtKB/Swiss-Prot
MGD MGI:1916359 ENTREZGENE
NCBI Gene 69109 ENTREZGENE
PANTHER PTHR10026 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10026:SF70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Cyclin_N UniProtKB/Swiss-Prot
PhenoGen Ccnq PhenoGen
SMART CYCLIN UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47954 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CCNQ_MOUSE UniProtKB/Swiss-Prot
  Q330K0_MOUSE UniProtKB/TrEMBL
  Q8QZR8 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-08-01 Ccnq  cyclin Q  Fam58b  family with sequence similarity 58, member B  Symbol and/or name change 5135510 APPROVED