IL1F10 (interleukin 1 family member 10) - Rat Genome Database

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Gene: IL1F10 (interleukin 1 family member 10) Homo sapiens
Analyze
Symbol: IL1F10
Name: interleukin 1 family member 10
RGD ID: 1313781
HGNC Page HGNC:15552
Description: Predicted to enable cytokine activity. Predicted to be involved in several processes, including cellular response to lipopolysaccharide; cytokine-mediated signaling pathway; and inflammatory response to antigenic stimulus. Predicted to be located in extracellular region. Predicted to be active in extracellular space.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: family of interleukin 1-theta; FIL1 theta; FIL1-theta; FKSG75; IL-1 theta; IL-1F10 (canonical form IL-1F10a); IL-1HY2; IL-38; IL1-theta; IL1HY2; interleukin 1 family member 10 (theta); interleukin 1 family, member 10 (theta); interleukin-1 family member 10; interleukin-1 HY2; interleukin-1 receptor antagonist FKSG75; interleukin-1 receptor antagonist-like FIL1 theta; interleukin-1 theta; interleukin-38; MGC119831; MGC119832; MGC119833
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382113,067,970 - 113,075,843 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2113,067,970 - 113,075,843 (+)EnsemblGRCh38hg38GRCh38
GRCh372113,825,547 - 113,833,420 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,542,018 - 113,549,898 (+)NCBINCBI36Build 36hg18NCBI36
Build 342113,541,777 - 113,549,656NCBI
Celera2107,210,716 - 107,218,594 (+)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2106,280,459 - 106,288,339 (+)NCBIHuRef
CHM1_12113,829,698 - 113,837,578 (+)NCBICHM1_1
T2T-CHM13v2.02113,494,498 - 113,502,373 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
Endometriosis  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8188271   PMID:9169134   PMID:10512743   PMID:10625660   PMID:10744718   PMID:10860666   PMID:11093146   PMID:11145836   PMID:11278614   PMID:11466363   PMID:11574262   PMID:11747621  
PMID:11991722   PMID:11991723   PMID:12477932   PMID:12975309   PMID:15489334   PMID:15815621   PMID:16361275   PMID:17975119   PMID:18063673   PMID:18361937   PMID:18464913   PMID:18484691  
PMID:19023099   PMID:19913121   PMID:20141484   PMID:20237496   PMID:20628086   PMID:20800603   PMID:20959797   PMID:20975573   PMID:21300955   PMID:21873635   PMID:22312160   PMID:22315422  
PMID:22939635   PMID:23969696   PMID:24182552   PMID:24969107   PMID:26314375   PMID:26819499   PMID:27182162   PMID:27438823   PMID:27723569   PMID:28288964   PMID:28514442   PMID:28942884  
PMID:29056011   PMID:30022755   PMID:30268016   PMID:30377293   PMID:30643810   PMID:30901679   PMID:30917443   PMID:31387327   PMID:31756565   PMID:31786620   PMID:31846791   PMID:31927461  
PMID:31957702   PMID:32259663   PMID:32296183   PMID:32502922   PMID:32601180   PMID:32653939   PMID:32736334   PMID:32950755   PMID:33079487   PMID:33125159   PMID:33383445   PMID:33414457  
PMID:33620105   PMID:33693700   PMID:33725637   PMID:33774357   PMID:33961781   PMID:34157522   PMID:34612721   PMID:34783147   PMID:34830435   PMID:35049442   PMID:35583912   PMID:35693797  
PMID:35833307   PMID:35902929   PMID:35948957   PMID:35961432   PMID:36016926   PMID:36301025   PMID:36375233   PMID:36376594   PMID:36397279   PMID:36519654   PMID:36894821   PMID:37702180  
PMID:37906644   PMID:38154209   PMID:38334236   PMID:38372219  


Genomics

Comparative Map Data
IL1F10
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382113,067,970 - 113,075,843 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2113,067,970 - 113,075,843 (+)EnsemblGRCh38hg38GRCh38
GRCh372113,825,547 - 113,833,420 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362113,542,018 - 113,549,898 (+)NCBINCBI36Build 36hg18NCBI36
Build 342113,541,777 - 113,549,656NCBI
Celera2107,210,716 - 107,218,594 (+)NCBICelera
Cytogenetic Map2q14.1NCBI
HuRef2106,280,459 - 106,288,339 (+)NCBIHuRef
CHM1_12113,829,698 - 113,837,578 (+)NCBICHM1_1
T2T-CHM13v2.02113,494,498 - 113,502,373 (+)NCBIT2T-CHM13v2.0
Il1f10
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39224,177,095 - 24,184,236 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl224,181,208 - 24,183,832 (+)EnsemblGRCm39 Ensembl
GRCm38224,291,196 - 24,294,165 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl224,291,196 - 24,293,820 (+)EnsemblGRCm38mm10GRCm38
MGSCv37224,146,716 - 24,149,340 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36224,113,205 - 24,115,829 (+)NCBIMGSCv36mm8
Celera224,010,634 - 24,013,238 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map216.32NCBI
Il1f10
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8327,470,798 - 27,473,726 (+)NCBIGRCr8
mRatBN7.237,072,511 - 7,075,439 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl37,072,511 - 7,075,439 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx310,177,836 - 10,180,763 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0318,764,063 - 18,766,990 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0316,953,873 - 16,956,800 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.031,408,560 - 1,416,601 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl31,413,671 - 1,416,599 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.031,406,826 - 1,409,754 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.432,558,491 - 2,561,419 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.132,560,014 - 2,561,353 (+)NCBI
Celera31,909,410 - 1,912,338 (+)NCBICelera
Cytogenetic Map3p13NCBI
Il1f10
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554701,198,134 - 1,206,199 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554701,198,185 - 1,206,032 (-)NCBIChiLan1.0ChiLan1.0
IL1F10
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21215,113,584 - 15,121,456 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A15,116,349 - 15,124,221 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A89,048,426 - 89,056,299 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A114,013,096 - 114,020,966 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A114,017,436 - 114,020,966 (+)Ensemblpanpan1.1panPan2
IL1F10
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11737,192,357 - 37,202,519 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1737,192,175 - 37,202,044 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1736,954,585 - 36,972,434 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01737,961,452 - 37,979,301 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11737,096,852 - 37,114,701 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01737,153,357 - 37,171,206 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01737,367,137 - 37,384,988 (+)NCBIUU_Cfam_GSD_1.0
Il1f10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629282,514,925 - 82,522,617 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367831,414,359 - 1,416,715 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367831,414,359 - 1,416,715 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IL1F10
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11416,087,676 - 16,097,214 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1416,093,289 - 16,095,927 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660803,584,494 - 3,592,485 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Il1f10
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474913,150,989 - 13,153,497 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474913,150,717 - 13,153,907 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in IL1F10
12 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 2q14.1(chr2:112924872-113105404)x1 copy number loss See cases [RCV000053808] Chr2:112924872..113105404 [GRCh38]
Chr2:113682449..113862981 [GRCh37]
Chr2:113398920..113579452 [NCBI36]
Chr2:2q14.1		 uncertain significance
GRCh37/hg19 2q12.2-14.1(chr2:106423310-115054828)x1 copy number loss See cases [RCV000240053] Chr2:106423310..115054828 [GRCh37]
Chr2:2q12.2-14.1		 pathogenic
GRCh37/hg19 2q12.3-14.3(chr2:109798247-125658380)x1 copy number loss See cases [RCV000240485] Chr2:109798247..125658380 [GRCh37]
Chr2:2q12.3-14.3		 pathogenic
GRCh37/hg19 2q12.3-14.1(chr2:109556627-117570152)x1 copy number loss See cases [RCV000240490] Chr2:109556627..117570152 [GRCh37]
Chr2:2q12.3-14.1		 pathogenic
GRCh37/hg19 2q13(chr2:113735617-113891118)x1 copy number loss See cases [RCV000448884] Chr2:113735617..113891118 [GRCh37]
Chr2:2q13		 benign
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q12.1-24.3(chr2:104172062-168223828)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626436] Chr2:104172062..168223828 [GRCh37]
Chr2:2q12.1-24.3		 drug response
Single allele deletion not provided [RCV000714264] Chr2:40608411..146900718 [GRCh37]
Chr2:2p22.1-q22.3		 likely pathogenic
GRCh37/hg19 2q13(chr2:113698135-114064263)x1 copy number loss not provided [RCV000682066] Chr2:113698135..114064263 [GRCh37]
Chr2:2q13		 uncertain significance
GRCh37/hg19 2q11.1-13(chr2:96353030-114045463)x3 copy number gain not provided [RCV000682168] Chr2:96353030..114045463 [GRCh37]
Chr2:2q11.1-13		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NM_173161.3(IL1F10):c.183C>T (p.Ile61=) single nucleotide variant not provided [RCV000900734] Chr2:113074787 [GRCh38]
Chr2:113832364 [GRCh37]
Chr2:2q14.1		 likely benign
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2q13(chr2:113717386-113892774)x1 copy number loss not provided [RCV000847007] Chr2:113717386..113892774 [GRCh37]
Chr2:2q13		 pathogenic
NC_000002.12:g.(?_113060832)_(113116890_?)del deletion Generalized pustular psoriasis [RCV001032679] Chr2:113818409..113874467 [GRCh37]
Chr2:2q13		 likely pathogenic
GRCh37/hg19 2q13-14.1(chr2:113609489-115817535)x3 copy number gain not provided [RCV001833062] Chr2:113609489..115817535 [GRCh37]
Chr2:2q13-14.1		 uncertain significance
GRCh37/hg19 2q13(chr2:113295194-114085649)x3 copy number gain not provided [RCV001834499] Chr2:113295194..114085649 [GRCh37]
Chr2:2q13		 uncertain significance
NC_000002.12:g.(?_112924872)_(113105404_?)del deletion Endometriosis [RCV001824107] Chr2:112924872..113105404 [GRCh38]
Chr2:2q14.1		 uncertain significance
GRCh37/hg19 2q13-14.3(chr2:113188197-128144700) copy number loss not specified [RCV002053220] Chr2:113188197..128144700 [GRCh37]
Chr2:2q13-14.3		 pathogenic
GRCh37/hg19 2q13-22.3(chr2:111484468-146333604)x3 copy number gain not provided [RCV001832896] Chr2:111484468..146333604 [GRCh37]
Chr2:2q13-22.3		 pathogenic
NC_000002.11:g.(?_113817016)_(113890448_?)del deletion Generalized pustular psoriasis [RCV003120785]|Sterile multifocal osteomyelitis with periostitis and pustulosis [RCV001963059] Chr2:113817016..113890448 [GRCh37]
Chr2:2q13		 pathogenic
GRCh37/hg19 2q13-22.3(chr2:112475655-145691999)x3 copy number gain 2q13q22.3 microduplication syndrome [RCV002226436] Chr2:112475655..145691999 [GRCh37]
Chr2:2q13-22.3		 pathogenic
NM_173161.3(IL1F10):c.133C>T (p.Leu45Phe) single nucleotide variant Inborn genetic diseases [RCV002752583] Chr2:113074737 [GRCh38]
Chr2:113832314 [GRCh37]
Chr2:2q14.1		 uncertain significance
NM_173161.3(IL1F10):c.196C>T (p.Arg66Cys) single nucleotide variant Inborn genetic diseases [RCV002859086] Chr2:113074800 [GRCh38]
Chr2:113832377 [GRCh37]
Chr2:2q14.1		 likely benign
NM_173161.3(IL1F10):c.154C>T (p.Arg52Cys) single nucleotide variant Inborn genetic diseases [RCV002987065] Chr2:113074758 [GRCh38]
Chr2:113832335 [GRCh37]
Chr2:2q14.1		 uncertain significance
NM_173161.3(IL1F10):c.293G>A (p.Arg98His) single nucleotide variant Inborn genetic diseases [RCV002960654] Chr2:113075198 [GRCh38]
Chr2:113832775 [GRCh37]
Chr2:2q14.1		 uncertain significance
NM_173161.3(IL1F10):c.91G>A (p.Asp31Asn) single nucleotide variant Inborn genetic diseases [RCV002678156] Chr2:113074387 [GRCh38]
Chr2:113831964 [GRCh37]
Chr2:2q14.1		 uncertain significance
NM_173161.3(IL1F10):c.290C>G (p.Thr97Arg) single nucleotide variant Inborn genetic diseases [RCV003189312] Chr2:113075195 [GRCh38]
Chr2:113832772 [GRCh37]
Chr2:2q14.1		 uncertain significance
NM_173161.3(IL1F10):c.163G>A (p.Val55Ile) single nucleotide variant Inborn genetic diseases [RCV003341416] Chr2:113074767 [GRCh38]
Chr2:113832344 [GRCh37]
Chr2:2q14.1		 uncertain significance
NM_173161.3(IL1F10):c.158C>A (p.Thr53Asn) single nucleotide variant Inborn genetic diseases [RCV003343274] Chr2:113074762 [GRCh38]
Chr2:113832339 [GRCh37]
Chr2:2q14.1		 uncertain significance
GRCh37/hg19 2q12.2-21.2(chr2:106755586-134302739)x1 copy number loss not specified [RCV003986380] Chr2:106755586..134302739 [GRCh37]
Chr2:2q12.2-21.2		 pathogenic
GRCh37/hg19 2q13(chr2:113717386-113892480)x1 copy number loss not specified [RCV003986332] Chr2:113717386..113892480 [GRCh37]
Chr2:2q13		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:841
Count of miRNA genes:248
Interacting mature miRNAs:264
Transcripts:ENST00000337569, ENST00000341010, ENST00000393197, ENST00000496265
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-106894  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372113,826,148 - 113,826,489UniSTSGRCh37
Build 362113,542,619 - 113,542,960RGDNCBI36
Celera2107,211,316 - 107,211,657RGD
Cytogenetic Map2q13UniSTS
HuRef2106,281,060 - 106,281,401UniSTS
TNG Radiation Hybrid Map264588.0UniSTS
IL1F10_3319  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh372113,832,736 - 113,833,526UniSTSGRCh37
Build 362113,549,207 - 113,549,997RGDNCBI36
Celera2107,217,903 - 107,218,693RGD
HuRef2106,287,648 - 106,288,438UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 646 1 433
Low 1 1 22 6 3 641 2 22 3 27 9 8 6 262 2
Below cutoff 291 305 317 73 124 33 359 224 389 26 385 322 47 150 238

Sequence


Reference Sequences
RefSeq Acc Id: ENST00000341010   ⟹   ENSP00000341794
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,067,970 - 113,075,843 (+)Ensembl
RefSeq Acc Id: ENST00000393197   ⟹   ENSP00000376893
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,072,318 - 113,075,843 (+)Ensembl
RefSeq Acc Id: ENST00000496265
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl2113,074,539 - 113,075,739 (+)Ensembl
RefSeq Acc Id: NM_032556   ⟹   NP_115945
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382113,072,318 - 113,075,843 (+)NCBI
GRCh372113,825,547 - 113,833,427 (+)ENTREZGENE
Build 362113,546,366 - 113,549,898 (+)NCBI Archive
HuRef2106,280,459 - 106,288,339 (+)ENTREZGENE
CHM1_12113,834,046 - 113,837,578 (+)NCBI
T2T-CHM13v2.02113,498,844 - 113,502,373 (+)NCBI
Sequence:
RefSeq Acc Id: NM_173161   ⟹   NP_775184
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh382113,067,970 - 113,075,843 (+)NCBI
GRCh372113,825,547 - 113,833,427 (+)ENTREZGENE
Build 362113,542,018 - 113,549,898 (+)NCBI Archive
HuRef2106,280,459 - 106,288,339 (+)ENTREZGENE
CHM1_12113,829,698 - 113,837,578 (+)NCBI
T2T-CHM13v2.02113,494,498 - 113,502,373 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_775184   ⟸   NM_173161
- UniProtKB: Q969H5 (UniProtKB/Swiss-Prot),   Q7RTZ5 (UniProtKB/Swiss-Prot),   Q56AT8 (UniProtKB/Swiss-Prot),   Q53SR9 (UniProtKB/Swiss-Prot),   Q9BYX1 (UniProtKB/Swiss-Prot),   Q8WWZ1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_115945   ⟸   NM_032556
- UniProtKB: Q969H5 (UniProtKB/Swiss-Prot),   Q7RTZ5 (UniProtKB/Swiss-Prot),   Q56AT8 (UniProtKB/Swiss-Prot),   Q53SR9 (UniProtKB/Swiss-Prot),   Q9BYX1 (UniProtKB/Swiss-Prot),   Q8WWZ1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000376893   ⟸   ENST00000393197
RefSeq Acc Id: ENSP00000341794   ⟸   ENST00000341010

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8WWZ1-F1-model_v2 AlphaFold Q8WWZ1 1-152 view protein structure

Promoters
RGD ID:6861384
Promoter ID:EPDNEW_H3857
Type:single initiation site
Name:IL1F10_2
Description:interleukin 1 family member 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H3858  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382113,067,970 - 113,068,030EPDNEW
RGD ID:6861386
Promoter ID:EPDNEW_H3858
Type:multiple initiation site
Name:IL1F10_1
Description:interleukin 1 family member 10
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H3857  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh382113,072,410 - 113,072,470EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:15552 AgrOrtholog
COSMIC IL1F10 COSMIC
Ensembl Genes ENSG00000136697 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000341010 ENTREZGENE
  ENST00000341010.6 UniProtKB/Swiss-Prot
  ENST00000393197 ENTREZGENE
  ENST00000393197.3 UniProtKB/Swiss-Prot
Gene3D-CATH 2.80.10.50 UniProtKB/Swiss-Prot
GTEx ENSG00000136697 GTEx
HGNC ID HGNC:15552 ENTREZGENE
Human Proteome Map IL1F10 Human Proteome Map
InterPro IL-1_fam UniProtKB/Swiss-Prot
  IL-1RA/IL-36 UniProtKB/Swiss-Prot
  IL1/FGF UniProtKB/Swiss-Prot
KEGG Report hsa:84639 UniProtKB/Swiss-Prot
NCBI Gene 84639 ENTREZGENE
OMIM 615296 OMIM
PANTHER PTHR10078 UniProtKB/Swiss-Prot
  PTHR10078:SF29 UniProtKB/Swiss-Prot
Pfam IL1 UniProtKB/Swiss-Prot
PharmGKB PA38387 PharmGKB
PRINTS INTERLEUKIN1 UniProtKB/Swiss-Prot
  INTRLEUKIN1X UniProtKB/Swiss-Prot
SMART IL1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50353 UniProtKB/Swiss-Prot
UniProt IL1FA_HUMAN UniProtKB/Swiss-Prot
  Q53SR9 ENTREZGENE
  Q56AT8 ENTREZGENE
  Q7RTZ5 ENTREZGENE
  Q8WWZ1 ENTREZGENE
  Q969H5 ENTREZGENE
  Q9BYX1 ENTREZGENE
UniProt Secondary Q53SR9 UniProtKB/Swiss-Prot
  Q56AT8 UniProtKB/Swiss-Prot
  Q7RTZ5 UniProtKB/Swiss-Prot
  Q969H5 UniProtKB/Swiss-Prot
  Q9BYX1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-08-15 IL1F10  interleukin 1 family member 10  IL1F10  interleukin 1 family member 10 (theta)  Symbol and/or name change 5135510 APPROVED
2015-11-24 IL1F10  interleukin 1 family member 10 (theta)  IL1F10  interleukin 1 family, member 10 (theta)  Symbol and/or name change 5135510 APPROVED