PFDN1 (prefoldin subunit 1) - Rat Genome Database

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Gene: PFDN1 (prefoldin subunit 1) Homo sapiens
Analyze
Symbol: PFDN1
Name: prefoldin subunit 1
RGD ID: 1313729
HGNC Page HGNC:8866
Description: Enables amyloid-beta binding activity; protein folding chaperone; and unfolded protein binding activity. Involved in negative regulation of amyloid fibril formation and protein folding. Part of prefoldin complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: PDF; PFD1; prefoldin 1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: PFDN1P1   PFDN1P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,245,035 - 140,303,101 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,245,035 - 140,303,113 (-)EnsemblGRCh38hg38GRCh38
GRCh375139,624,620 - 139,682,686 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365139,604,819 - 139,662,873 (-)NCBINCBI36Build 36hg18NCBI36
Build 345139,604,835 - 139,662,847NCBI
Celera5135,701,310 - 135,759,316 (-)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5134,769,914 - 134,827,849 (-)NCBIHuRef
CHM1_15139,057,759 - 139,115,827 (-)NCBICHM1_1
T2T-CHM13v2.05140,770,478 - 140,828,531 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA)
prefoldin complex  (IDA,IEA,NAS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8125298   PMID:8744932   PMID:9630229   PMID:10191080   PMID:10209023   PMID:10542082   PMID:11521196   PMID:11535601   PMID:11884745   PMID:12456645   PMID:12477932   PMID:12748950  
PMID:14615539   PMID:14634002   PMID:14702039   PMID:15489334   PMID:16169070   PMID:16415341   PMID:16876117   PMID:17353931   PMID:18029348   PMID:19615732   PMID:20360068   PMID:21873635  
PMID:21900206   PMID:22844532   PMID:22863883   PMID:22939629   PMID:23349634   PMID:23602568   PMID:23614719   PMID:23658844   PMID:23741361   PMID:24981860   PMID:25900982   PMID:26344197  
PMID:26496610   PMID:26553318   PMID:26638075   PMID:26972000   PMID:27432908   PMID:27684187   PMID:27694898   PMID:28183528   PMID:28514442   PMID:28718761   PMID:29395067   PMID:29531219  
PMID:29568061   PMID:30955883   PMID:31182584   PMID:31900314   PMID:31980649   PMID:32203420   PMID:32296183   PMID:32513696   PMID:32694731   PMID:32699605   PMID:32707033   PMID:32877691  
PMID:33111431   PMID:33137104   PMID:33306668   PMID:33417871   PMID:33961781   PMID:34373451   PMID:34709727   PMID:35140242   PMID:35217267   PMID:35253629   PMID:35271311   PMID:35384245  
PMID:35446349   PMID:35944360   PMID:37536630   PMID:37689310  


Genomics

Comparative Map Data
PFDN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385140,245,035 - 140,303,101 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5140,245,035 - 140,303,113 (-)EnsemblGRCh38hg38GRCh38
GRCh375139,624,620 - 139,682,686 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365139,604,819 - 139,662,873 (-)NCBINCBI36Build 36hg18NCBI36
Build 345139,604,835 - 139,662,847NCBI
Celera5135,701,310 - 135,759,316 (-)NCBICelera
Cytogenetic Map5q31.3NCBI
HuRef5134,769,914 - 134,827,849 (-)NCBIHuRef
CHM1_15139,057,759 - 139,115,827 (-)NCBICHM1_1
T2T-CHM13v2.05140,770,478 - 140,828,531 (-)NCBIT2T-CHM13v2.0
Pfdn1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391836,536,732 - 36,587,548 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1836,536,729 - 36,587,577 (-)EnsemblGRCm39 Ensembl
GRCm381836,403,679 - 36,454,495 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1836,403,676 - 36,454,524 (-)EnsemblGRCm38mm10GRCm38
MGSCv371836,563,333 - 36,614,149 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361836,529,653 - 36,580,469 (-)NCBIMGSCv36mm8
Celera1836,859,471 - 36,910,850 (-)NCBICelera
Cytogenetic Map18B2NCBI
cM Map1819.46NCBI
Pfdn1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81828,288,210 - 28,341,198 (-)NCBIGRCr8
mRatBN7.21828,014,145 - 28,067,148 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1828,014,145 - 28,067,064 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1828,141,323 - 28,194,236 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01828,903,409 - 28,956,326 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01828,238,656 - 28,291,565 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01829,233,987 - 29,290,447 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1829,233,987 - 29,290,447 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01828,940,034 - 28,997,334 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41829,043,386 - 29,096,475 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11829,070,391 - 29,138,459 (-)NCBI
Celera1827,742,853 - 27,795,443 (-)NCBICelera
Cytogenetic Map18p11NCBI
Pfdn1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_004955418351,078 - 414,292 (+)NCBIChiLan1.0ChiLan1.0
PFDN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24135,504,946 - 135,564,989 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15133,644,503 - 133,702,578 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05135,611,791 - 135,669,895 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15141,729,128 - 141,786,822 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5141,729,128 - 141,786,822 (-)Ensemblpanpan1.1panPan2
PFDN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1235,454,139 - 35,519,818 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl235,454,404 - 35,519,725 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha232,557,224 - 32,588,680 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0235,909,878 - 35,975,476 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl235,907,816 - 35,975,361 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1232,961,926 - 33,027,195 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0233,829,331 - 33,894,632 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0234,582,250 - 34,647,518 (-)NCBIUU_Cfam_GSD_1.0
Pfdn1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213152,296,230 - 152,359,310 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365319,252,216 - 9,311,581 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365319,252,195 - 9,311,531 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PFDN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2142,011,063 - 142,077,925 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.12142,011,568 - 142,078,000 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22147,954,676 - 148,021,374 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PFDN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12342,892,818 - 42,953,540 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2342,892,401 - 42,953,491 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603434,931,427 - 34,992,605 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pfdn1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474333,012,922 - 33,083,654 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474333,012,920 - 33,083,776 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in PFDN1
6 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 5q23.3-33.2(chr5:130860928-155321811)x3 copy number gain See cases [RCV000051193] Chr5:130860928..155321811 [GRCh38]
Chr5:130196621..154701371 [GRCh37]
Chr5:130224520..154681564 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh38/hg38 5q31.2-32(chr5:138871137-145812309)x1 copy number loss See cases [RCV000052142] Chr5:138871137..145812309 [GRCh38]
Chr5:138206826..145191872 [GRCh37]
Chr5:138234725..145172065 [NCBI36]
Chr5:5q31.2-32
pathogenic
GRCh38/hg38 5q21.3-33.2(chr5:106619588-156124387)x1 copy number loss See cases [RCV000053524] Chr5:106619588..156124387 [GRCh38]
Chr5:105955289..155551397 [GRCh37]
Chr5:105983188..155483975 [NCBI36]
Chr5:5q21.3-33.2
pathogenic
GRCh38/hg38 5q31.2-31.3(chr5:137836682-140696361)x3 copy number gain See cases [RCV000134725] Chr5:137836682..140696361 [GRCh38]
Chr5:137172371..140075946 [GRCh37]
Chr5:137200270..140056130 [NCBI36]
Chr5:5q31.2-31.3
pathogenic
GRCh38/hg38 5q23.3-33.2(chr5:129847794-153353546)x3 copy number gain See cases [RCV000138808] Chr5:129847794..153353546 [GRCh38]
Chr5:129183487..152733106 [GRCh37]
Chr5:129211386..152713299 [NCBI36]
Chr5:5q23.3-33.2
pathogenic
GRCh38/hg38 5q31.2-31.3(chr5:138942857-144605017)x3 copy number gain See cases [RCV000142806] Chr5:138942857..144605017 [GRCh38]
Chr5:138278546..143984580 [GRCh37]
Chr5:138306445..143964773 [NCBI36]
Chr5:5q31.2-31.3
uncertain significance
GRCh37/hg19 5q15-35.3(chr5:94844077-178830410)x3 copy number gain not provided [RCV000487658] Chr5:94844077..178830410 [GRCh37]
Chr5:5q15-35.3
likely benign
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910)x3 copy number gain See cases [RCV000449349] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789) copy number gain See cases [RCV000510723] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5q21.3-35.3(chr5:106716357-180687338)x3 copy number gain See cases [RCV000448245] Chr5:106716357..180687338 [GRCh37]
Chr5:5q21.3-35.3
pathogenic
GRCh37/hg19 5p15.1-q35.2(chr5:17628741-176575720)x1 copy number loss See cases [RCV000511978] Chr5:17628741..176575720 [GRCh37]
Chr5:5p15.1-q35.2
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:113577-180719789)x3 copy number gain See cases [RCV000512039] Chr5:113577..180719789 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
NM_002622.5(PFDN1):c.244G>C (p.Glu82Gln) single nucleotide variant Inborn genetic diseases [RCV003293209] Chr5:140281490 [GRCh38]
Chr5:139661075 [GRCh37]
Chr5:5q31.3
uncertain significance
NC_000005.9:g.(?_86400000)_(154000000_?)del deletion Familial adenomatous polyposis 1 [RCV002231249]|Hereditary cancer-predisposing syndrome [RCV000554476] Chr5:86400000..154000000 [GRCh37]
Chr5:5q14.3-33.2
pathogenic
GRCh37/hg19 5q31.2-31.3(chr5:139147238-141540491)x1 copy number loss not provided [RCV000682600] Chr5:139147238..141540491 [GRCh37]
Chr5:5q31.2-31.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:25328-180693344)x3 copy number gain not provided [RCV000744323] Chr5:25328..180693344 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
GRCh37/hg19 5p15.33-q35.3(chr5:13648-180905029)x3 copy number gain not provided [RCV000744317] Chr5:13648..180905029 [GRCh37]
Chr5:5p15.33-q35.3
pathogenic
Single allele deletion Neurodevelopmental disorder [RCV000787436] Chr5:14685137..149511942 [GRCh37]
Chr5:5p15.2-q32
uncertain significance
GRCh37/hg19 5q31.2-31.3(chr5:139447779-140047037)x3 copy number gain not provided [RCV000846756] Chr5:139447779..140047037 [GRCh37]
Chr5:5q31.2-31.3
uncertain significance
NC_000005.9:g.(?_136633338)_(140998481_?)dup duplication PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome [RCV001339088] Chr5:136633338..140998481 [GRCh37]
Chr5:5q31.2-31.3
uncertain significance
GRCh37/hg19 5q31.2-31.3(chr5:139493717-140517454)x1 copy number loss PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome [RCV001801202] Chr5:139493717..140517454 [GRCh37]
Chr5:5q31.2-31.3
pathogenic
GRCh37/hg19 5q23.3-33.3(chr5:130125085-157574910) copy number gain not specified [RCV002053526] Chr5:130125085..157574910 [GRCh37]
Chr5:5q23.3-33.3
pathogenic
NC_000005.9:g.(?_136957787)_(140078137_?)dup duplication PURA-related severe neonatal hypotonia-seizures-encephalopathy syndrome [RCV003116437] Chr5:136957787..140078137 [GRCh37]
Chr5:5q31.2-31.3
uncertain significance
NM_002622.5(PFDN1):c.110T>G (p.Leu37Arg) single nucleotide variant Inborn genetic diseases [RCV002839774] Chr5:140300506 [GRCh38]
Chr5:139680091 [GRCh37]
Chr5:5q31.3
uncertain significance
NM_002622.5(PFDN1):c.222A>C (p.Glu74Asp) single nucleotide variant Inborn genetic diseases [RCV002946052] Chr5:140281512 [GRCh38]
Chr5:139661097 [GRCh37]
Chr5:5q31.3
uncertain significance
NM_002622.5(PFDN1):c.94A>G (p.Ile32Val) single nucleotide variant Inborn genetic diseases [RCV002714035] Chr5:140300522 [GRCh38]
Chr5:139680107 [GRCh37]
Chr5:5q31.3
uncertain significance
NM_002622.5(PFDN1):c.308G>A (p.Arg103Gln) single nucleotide variant Inborn genetic diseases [RCV003358698] Chr5:140246035 [GRCh38]
Chr5:139625620 [GRCh37]
Chr5:5q31.3
uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2060
Count of miRNA genes:745
Interacting mature miRNAs:865
Transcripts:ENST00000261813, ENST00000507185, ENST00000510217, ENST00000512707, ENST00000512925, ENST00000514611, ENST00000524074
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-81793  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375139,647,752 - 139,647,961UniSTSGRCh37
Build 365139,627,936 - 139,628,145RGDNCBI36
Celera5135,724,400 - 135,724,609RGD
Cytogenetic Map5q31UniSTS
HuRef5134,792,930 - 134,793,139UniSTS
TNG Radiation Hybrid Map564589.0UniSTS
SHGC-81794  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375139,647,752 - 139,647,961UniSTSGRCh37
Build 365139,627,936 - 139,628,145RGDNCBI36
Celera5135,724,400 - 135,724,609RGD
Cytogenetic Map5q31UniSTS
HuRef5134,792,930 - 134,793,139UniSTS
TNG Radiation Hybrid Map564581.0UniSTS
GDB:451806  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375139,624,846 - 139,624,938UniSTSGRCh37
GRCh37312,370,387 - 12,370,479UniSTSGRCh37
Build 36312,345,387 - 12,345,479RGDNCBI36
Celera5135,701,521 - 135,701,613UniSTS
Celera312,307,781 - 12,307,873RGD
Cytogenetic Map5q31UniSTS
Cytogenetic Map3p25UniSTS
HuRef5134,770,125 - 134,770,217UniSTS
HuRef312,303,740 - 12,303,832UniSTS
RH10742  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375139,624,713 - 139,624,911UniSTSGRCh37
GRCh37312,370,414 - 12,370,612UniSTSGRCh37
Build 36312,345,414 - 12,345,612RGDNCBI36
Celera5135,701,388 - 135,701,586UniSTS
Celera312,307,808 - 12,308,006RGD
Cytogenetic Map5q31UniSTS
Cytogenetic Map3p25UniSTS
HuRef5134,769,992 - 134,770,190UniSTS
HuRef312,303,767 - 12,303,965UniSTS
WI-20399  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh375139,624,837 - 139,625,101UniSTSGRCh37
GRCh37312,370,223 - 12,370,488UniSTSGRCh37
Build 36312,345,223 - 12,345,488RGDNCBI36
Celera312,307,617 - 12,307,882RGD
Celera5135,701,512 - 135,701,776UniSTS
Cytogenetic Map3p25UniSTS
Cytogenetic Map5q31UniSTS
HuRef312,303,576 - 12,303,841UniSTS
HuRef5134,770,116 - 134,770,380UniSTS
GeneMap99-GB4 RH Map5531.42UniSTS
Whitehead-RH Map5441.7UniSTS
NCBI RH Map5889.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2439 2788 1676 574 1794 415 4356 2149 3726 418 1460 1613 175 1 1204 2787 6 2
Low 203 50 50 157 50 1 48 8 1 1
Below cutoff

Sequence


RefSeq Acc Id: ENST00000261813   ⟹   ENSP00000261813
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5140,245,035 - 140,303,101 (-)Ensembl
RefSeq Acc Id: ENST00000507185
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5140,280,960 - 140,303,086 (-)Ensembl
RefSeq Acc Id: ENST00000510217   ⟹   ENSP00000426383
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5140,245,125 - 140,303,113 (-)Ensembl
RefSeq Acc Id: ENST00000512707
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5140,245,347 - 140,281,535 (-)Ensembl
RefSeq Acc Id: ENST00000512925
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5140,245,552 - 140,293,207 (-)Ensembl
RefSeq Acc Id: ENST00000514611
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5140,245,087 - 140,300,583 (-)Ensembl
RefSeq Acc Id: ENST00000524074   ⟹   ENSP00000428707
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl5140,245,448 - 140,303,083 (-)Ensembl
RefSeq Acc Id: NM_002622   ⟹   NP_002613
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385140,245,035 - 140,303,101 (-)NCBI
GRCh375139,624,635 - 139,682,689 (-)ENTREZGENE
Build 365139,604,819 - 139,662,873 (-)NCBI Archive
HuRef5134,769,914 - 134,827,849 (-)ENTREZGENE
CHM1_15139,057,759 - 139,115,827 (-)NCBI
T2T-CHM13v2.05140,770,478 - 140,828,531 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005268465   ⟹   XP_005268522
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh385140,269,670 - 140,303,101 (-)NCBI
GRCh375139,624,635 - 139,682,689 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054352822   ⟹   XP_054208797
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.05140,795,103 - 140,828,531 (-)NCBI
RefSeq Acc Id: NP_002613   ⟸   NM_002622
- UniProtKB: Q53F95 (UniProtKB/Swiss-Prot),   B2RD02 (UniProtKB/Swiss-Prot),   Q96EX6 (UniProtKB/Swiss-Prot),   O60925 (UniProtKB/Swiss-Prot),   E5RGS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005268522   ⟸   XM_005268465
- Peptide Label: isoform X1
- UniProtKB: E5RGS4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000426383   ⟸   ENST00000510217
RefSeq Acc Id: ENSP00000428707   ⟸   ENST00000524074
RefSeq Acc Id: ENSP00000261813   ⟸   ENST00000261813
RefSeq Acc Id: XP_054208797   ⟸   XM_054352822
- Peptide Label: isoform X1
- UniProtKB: E5RGS4 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O60925-F1-model_v2 AlphaFold O60925 1-122 view protein structure

Promoters
RGD ID:6803457
Promoter ID:HG_KWN:51259
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000251354,   UC003LFG.1
Position:
Human AssemblyChrPosition (strand)Source
Build 365139,662,711 - 139,663,211 (-)MPROMDB
RGD ID:6870788
Promoter ID:EPDNEW_H8559
Type:initiation region
Name:PFDN1_1
Description:prefoldin subunit 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh385140,303,090 - 140,303,150EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:8866 AgrOrtholog
COSMIC PFDN1 COSMIC
Ensembl Genes ENSG00000113068 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000261813 ENTREZGENE
  ENST00000261813.9 UniProtKB/Swiss-Prot
  ENST00000510217.1 UniProtKB/TrEMBL
  ENST00000524074.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.370 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000113068 GTEx
HGNC ID HGNC:8866 ENTREZGENE
Human Proteome Map PFDN1 Human Proteome Map
InterPro PFD_beta-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prefoldin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5201 UniProtKB/Swiss-Prot
NCBI Gene 5201 ENTREZGENE
OMIM 604897 OMIM
PANTHER PREFOLDIN SUBUNIT 1 UniProtKB/Swiss-Prot
  PREFOLDIN SUBUNIT 1 UniProtKB/TrEMBL
  PREFOLDIN SUBUNIT 1-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Prefoldin_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA33207 PharmGKB
Superfamily-SCOP Prefoldin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B2RD02 ENTREZGENE
  D6RGG5_HUMAN UniProtKB/TrEMBL
  E5RGS4 ENTREZGENE, UniProtKB/TrEMBL
  O60925 ENTREZGENE, UniProtKB/Swiss-Prot
  Q53F95 ENTREZGENE
  Q96EX6 ENTREZGENE
UniProt Secondary B2RD02 UniProtKB/Swiss-Prot
  Q53F95 UniProtKB/Swiss-Prot
  Q96EX6 UniProtKB/Swiss-Prot