Trappc14 (trafficking protein particle complex 14) - Rat Genome Database

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Gene: Trappc14 (trafficking protein particle complex 14) Mus musculus
Analyze
Symbol: Trappc14
Name: trafficking protein particle complex 14
RGD ID: 1313493
MGI Page MGI
Description: Predicted to enable alpha-tubulin binding activity. Predicted to be involved in cilium assembly and regulation of cell population proliferation. Predicted to act upstream of or within cell projection organization. Predicted to be located in several cellular components, including microtubule cytoskeleton; midbody; and plasma membrane. Predicted to be part of TRAPPII protein complex. Is expressed in liver; nervous system; neural retina; and thymus primordium. Human ortholog(s) of this gene implicated in primary autosomal recessive microcephaly. Orthologous to human TRAPPC14 (trafficking protein particle complex subunit 14).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: BC037034; cDNA sequence BC037034; hypothetical protein LOC231807; Map11; MAP11 short transcript; MGC47434; microtubule associated protein 11; microtubule-associated protein 11; trafficking protein particle complex subunit 14; uncharacterized protein C7orf43 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm8093  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,257,920 - 138,262,323 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,257,918 - 138,262,295 (-)EnsemblGRCm39 Ensembl
GRCm385138,259,658 - 138,264,061 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,259,656 - 138,264,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv375138,700,886 - 138,705,280 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,489,446 - 138,492,973 (-)NCBIMGSCv36mm8
Celera5135,242,510 - 135,246,904 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map577.0NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17114649   PMID:21267068  
PMID:21873635  


Genomics

Comparative Map Data
Trappc14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395138,257,920 - 138,262,323 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5138,257,918 - 138,262,295 (-)EnsemblGRCm39 Ensembl
GRCm385138,259,658 - 138,264,061 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5138,259,656 - 138,264,033 (-)EnsemblGRCm38mm10GRCm38
MGSCv375138,700,886 - 138,705,280 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365138,489,446 - 138,492,973 (-)NCBIMGSCv36mm8
Celera5135,242,510 - 135,246,904 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map577.0NCBI
TRAPPC14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,154,423 - 100,158,723 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,154,420 - 100,158,723 (-)EnsemblGRCh38hg38GRCh38
GRCh37799,752,046 - 99,756,346 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36799,589,979 - 99,594,238 (-)NCBINCBI36Build 36hg18NCBI36
Celera794,487,394 - 94,491,646 (-)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,387,014 - 94,391,191 (-)NCBIHuRef
CHM1_1799,682,170 - 99,686,429 (-)NCBICHM1_1
T2T-CHM13v2.07101,394,216 - 101,398,516 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,112,129 - 99,116,387 (-)NCBI
Trappc14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81222,376,361 - 22,380,706 (-)NCBIGRCr8
mRatBN7.21217,262,748 - 17,267,093 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1217,262,750 - 17,267,084 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1218,230,277 - 18,234,567 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,854,000 - 18,858,290 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01217,907,412 - 17,911,702 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01219,577,895 - 19,582,185 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1219,573,893 - 19,582,208 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01221,634,744 - 21,639,034 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41217,843,341 - 17,847,631 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11217,833,446 - 17,838,394 (-)NCBI
Celera1219,187,407 - 19,191,698 (-)NCBICelera
Cytogenetic Map12q11NCBI
Trappc14
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573645,587 - 649,363 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955573644,907 - 649,363 (+)NCBIChiLan1.0ChiLan1.0
TRAPPC14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,073,355 - 118,077,663 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,337,987 - 166,342,295 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,189,179 - 92,193,483 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17105,621,902 - 105,626,216 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7105,622,497 - 105,625,978 (-)Ensemblpanpan1.1panPan2
TRAPPC14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,368,006 - 9,372,493 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,368,029 - 9,373,043 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha611,071,992 - 11,076,486 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.069,301,680 - 9,306,164 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.169,154,164 - 9,158,662 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.069,133,226 - 9,137,704 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,314,289 - 9,318,777 (+)NCBIUU_Cfam_GSD_1.0
Trappc14
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,620,088 - 133,624,561 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543412,524 - 416,445 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543411,972 - 416,442 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRAPPC14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,158,070 - 8,162,425 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,158,062 - 8,162,738 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,359,744 - 7,364,018 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TRAPPC14
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,911,287 - 12,915,935 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,911,531 - 12,915,321 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,364,326 - 3,368,969 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Trappc14
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,748,281 - 16,756,542 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,748,276 - 16,752,580 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Trappc14
77 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2788
Count of miRNA genes:664
Interacting mature miRNAs:849
Transcripts:ENSMUST00000048421, ENSMUST00000159123, ENSMUST00000159146, ENSMUST00000159534, ENSMUST00000159649, ENSMUST00000159872, ENSMUST00000161604, ENSMUST00000162632
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
27226719Tibw6_mtibia width 6, proximal, 16 week (mouse)572857343139985755Mouse
1301362Prnr1_mprion resistance 1 (mouse)Not determined589418876146787935Mouse
10412202Bbaa26_mB.burgdorferi-associated arthritis 26 (mouse)Not determined5104583688138555455Mouse
10412239Alpq7_malcohol preference QTL 7 (mouse)Not determined5104705939138705939Mouse
10043890Trigq4_mtriglyceride QTL 4 (mouse)Not determined5107906299141906412Mouse
4142473Chlq11_mcirculating hormone level QTL 11 (mouse)Not determined5107906299141906412Mouse
13464243Ahl20_mage related hearing loss, early onset 20 (mouse)5107906299141906412Mouse
10412197Bbaa25_mB.burgdorferi-associated arthritis 25 (mouse)Not determined5109167240143167381Mouse
13464251Ahl21_mage related hearing loss, early onset 21 (mouse)5109167240143167381Mouse
1301543Hypch_mhypercholesterolemia (mouse)Not determined5109238624139118905Mouse
1300913Bwefm_mbody weight females and males day 10 (mouse)Not determined5109439348143439459Mouse
1301102Cia14_mcollagen induced arthritis 14 (mouse)Not determined5113320385138555455Mouse
1301226Bbaa2_mB.burgdorferi-associated arthritis 2 (mouse)Not determined5115156883149157015Mouse
1300827Cora1_mcorrelation in cytokine production 1 (mouse)Not determined5115156883149157015Mouse
1301857Bglq14_mbody growth late QTL 14 (mouse)Not determined5118948964151758149Mouse
10412191Bbaa24_mB.burgdorferi-associated arthritis 24 (mouse)Not determined5119945037141700466Mouse
4141081Nidd7k_mNidd7 on KK-A (mouse)Not determined119945037149347326Mouse
11528552Scram1_mspinal cord resistance to astrocytoma modifier 1 (mouse)5121455402151758149Mouse
1301986Bpq4_mblood pressure QTL 4 (mouse)Not determined5121555236151758149Mouse
1302079Lbw3_mlupus NZB x NZW 3 (mouse)Not determined5124700335151758149Mouse
1301363Pbwg13_mpostnatal body weight growth 13 (mouse)Not determined5125133457151758149Mouse
1301715Elmaz2_melevated maze behavior 2 (mouse)Not determined5125178229141700466Mouse
4141218Ath24_matherosclerosis 24 (mouse)Not determined129520084151758149Mouse
12880406Jcdq2_mjoint cartilage degeneration QTL 2 (mouse)5129787831151758149Mouse
13464143Bbaa2b_mB.burgdorferi-associated arthritis 2b (mouse)5133052969140709801Mouse
11049557Lmr26_mleishmaniasis resistance 26 (mouse)5133925558151758149Mouse

Markers in Region
AV006840  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm385138,259,251 - 138,259,345UniSTSGRCm38
MGSCv375138,700,479 - 138,700,573UniSTSGRCm37
Celera5135,242,103 - 135,242,197UniSTS
Cytogenetic Map5G2UniSTS
Whitehead/MRC_RH51670.77UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000048421   ⟹   ENSMUSP00000046898
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5138,257,918 - 138,262,256 (-)Ensembl
GRCm38.p6 Ensembl5138,259,656 - 138,263,994 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159123   ⟹   ENSMUSP00000137679
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5138,257,921 - 138,262,252 (-)Ensembl
GRCm38.p6 Ensembl5138,259,659 - 138,263,990 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159146   ⟹   ENSMUSP00000123724
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5138,258,367 - 138,259,207 (-)Ensembl
GRCm38.p6 Ensembl5138,260,105 - 138,260,945 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159534
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5138,257,922 - 138,262,295 (-)Ensembl
GRCm38.p6 Ensembl5138,259,660 - 138,264,033 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159649   ⟹   ENSMUSP00000125208
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5138,257,920 - 138,261,602 (-)Ensembl
GRCm38.p6 Ensembl5138,259,658 - 138,263,340 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159872
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5138,260,515 - 138,261,400 (-)Ensembl
GRCm38.p6 Ensembl5138,262,253 - 138,263,138 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162632
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl5138,259,832 - 138,260,456 (-)Ensembl
GRCm38.p6 Ensembl5138,261,570 - 138,262,194 (-)Ensembl
RefSeq Acc Id: NM_153161   ⟹   NP_694801
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395138,257,920 - 138,262,314 (-)NCBI
GRCm385138,259,658 - 138,264,052 (-)ENTREZGENE
MGSCv375138,700,886 - 138,705,280 (-)RGD
Celera5135,242,510 - 135,246,904 (-)RGD
cM Map5 ENTREZGENE
Sequence:
RefSeq Acc Id: XR_001784686
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395138,257,920 - 138,262,323 (-)NCBI
GRCm385138,259,658 - 138,264,061 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003955636
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm395138,257,920 - 138,262,323 (-)NCBI
GRCm385138,259,658 - 138,264,061 (-)NCBI
Sequence:
RefSeq Acc Id: NP_694801   ⟸   NM_153161
- UniProtKB: Q8JZV2 (UniProtKB/Swiss-Prot),   Q3UTZ3 (UniProtKB/Swiss-Prot),   E9Q2V5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000137679   ⟸   ENSMUST00000159123
RefSeq Acc Id: ENSMUSP00000123724   ⟸   ENSMUST00000159146
RefSeq Acc Id: ENSMUSP00000125208   ⟸   ENSMUST00000159649
RefSeq Acc Id: ENSMUSP00000046898   ⟸   ENSMUST00000048421

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q3UTZ3-F1-model_v2 AlphaFold Q3UTZ3 1-580 view protein structure

Promoters
RGD ID:6888514
Promoter ID:EPDNEW_M7708
Type:initiation region
Name:BC037034_1
Description:Mus musculus cDNA sequence BC037034 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm385138,264,037 - 138,264,097EPDNEW
RGD ID:6836966
Promoter ID:MM_KWN:44553
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000110924,   OTTMUST00000054611,   OTTMUST00000054612,   OTTMUST00000054613,   OTTMUST00000054614,   OTTMUST00000054615,   OTTMUST00000054616,   OTTMUST00000054617
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv365138,703,696 - 138,705,267 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2385896 AgrOrtholog
Ensembl Genes ENSMUSG00000036948 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000048421 ENTREZGENE
  ENSMUST00000048421.14 UniProtKB/Swiss-Prot
  ENSMUST00000159123 ENTREZGENE
  ENSMUST00000159123.8 UniProtKB/TrEMBL
  ENSMUST00000159146.2 UniProtKB/TrEMBL
  ENSMUST00000159649.8 UniProtKB/TrEMBL
InterPro DUF4707 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:231807 UniProtKB/Swiss-Prot
MGD MGI:2385896 ENTREZGENE
NCBI Gene 231807 ENTREZGENE
PANTHER PTHR16096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRAFFICKING PROTEIN PARTICLE COMPLEX SUBUNIT 14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF4707 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Trappc14 PhenoGen
UniProt A0A0G2JDC3_MOUSE UniProtKB/TrEMBL
  E9Q2V5 ENTREZGENE
  E9Q6X8_MOUSE UniProtKB/TrEMBL
  F6VAB1_MOUSE UniProtKB/TrEMBL
  MA11_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8JZV2 ENTREZGENE
UniProt Secondary E9Q2V5 UniProtKB/Swiss-Prot
  Q8JZV2 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-12-28 Trappc14  trafficking protein particle complex 14  Map11  microtubule associated protein 11  Symbol and/or name updated 27372883 PROVISIONAL
2019-02-26 Map11  microtubule associated protein 11  BC037034  cDNA sequence BC037034  Symbol and/or name change 5135510 APPROVED