Pomt2 (protein-O-mannosyltransferase 2) - Rat Genome Database

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Gene: Pomt2 (protein-O-mannosyltransferase 2) Mus musculus
Analyze
Symbol: Pomt2
Name: protein-O-mannosyltransferase 2
RGD ID: 1313481
MGI Page MGI
Description: Predicted to have dolichyl-phosphate-mannose-protein mannosyltransferase activity. Predicted to be involved in ER-associated misfolded protein catabolic process; positive regulation of protein O-linked glycosylation; and protein O-linked mannosylation. Predicted to localize to cytosol; endoplasmic reticulum membrane; and nuclear lumen. Is expressed in several structures, including central nervous system; craniocervical region bone; gonad; heart; and limb. Human ortholog(s) of this gene implicated in lissencephaly and muscular dystrophy (multiple). Orthologous to human POMT2 (protein O-mannosyltransferase 2).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: A830009D15Rik; AW046274; dolichyl-phosphate-mannose--protein mannosyltransferase 2; protein O-mannosyl-transferase 2
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391287,153,635 - 87,194,742 (-)NCBIGRCm39mm39
GRCm39 Ensembl1287,153,635 - 87,194,742 (-)Ensembl
GRCm381287,106,861 - 87,147,968 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1287,106,861 - 87,147,968 (-)EnsemblGRCm38mm10GRCm38
MGSCv371288,447,816 - 88,488,852 (-)NCBIGRCm37mm9NCBIm37
MGSCv361287,995,969 - 88,037,005 (-)NCBImm8
Celera1288,571,489 - 88,612,407 (-)NCBICelera
Cytogenetic Map12D2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12460945   PMID:12477932   PMID:12520002   PMID:14681479   PMID:15383666   PMID:15489334   PMID:15782199  
PMID:16141072   PMID:16141073   PMID:17456771   PMID:18490429   PMID:21267068   PMID:21452199   PMID:21873635   PMID:21970971   PMID:24256719   PMID:24297939   PMID:30550785  


Genomics

Comparative Map Data
Pomt2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391287,153,635 - 87,194,742 (-)NCBIGRCm39mm39
GRCm39 Ensembl1287,153,635 - 87,194,742 (-)Ensembl
GRCm381287,106,861 - 87,147,968 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1287,106,861 - 87,147,968 (-)EnsemblGRCm38mm10GRCm38
MGSCv371288,447,816 - 88,488,852 (-)NCBIGRCm37mm9NCBIm37
MGSCv361287,995,969 - 88,037,005 (-)NCBImm8
Celera1288,571,489 - 88,612,407 (-)NCBICelera
Cytogenetic Map12D2NCBI
POMT2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1477,274,956 - 77,320,884 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1477,274,956 - 77,320,883 (-)EnsemblGRCh38hg38GRCh38
GRCh381477,274,956 - 77,320,885 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371477,741,299 - 77,787,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361476,811,052 - 76,856,970 (-)NCBINCBI36hg18NCBI36
Build 341476,811,053 - 76,856,970NCBI
Celera1457,779,861 - 57,825,801 (-)NCBI
Cytogenetic Map14q24.3NCBI
HuRef1457,907,710 - 57,953,334 (-)NCBIHuRef
CHM1_11477,680,748 - 77,726,684 (-)NCBICHM1_1
Pomt2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.26106,755,462 - 106,794,849 (-)NCBI
Rnor_6.0 Ensembl6111,135,349 - 111,176,918 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.06111,137,329 - 111,176,991 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.06120,423,138 - 120,461,156 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.46111,242,085 - 111,259,180 (-)NCBIRGSC3.4rn4RGSC3.4
Celera6104,576,761 - 104,616,136 (-)NCBICelera
Cytogenetic Map6q31NCBI
Pomt2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554381,179,064 - 1,218,860 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554381,179,064 - 1,218,860 (-)NCBIChiLan1.0ChiLan1.0
POMT2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11477,029,625 - 77,075,819 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1477,029,625 - 77,075,806 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01457,827,841 - 57,874,100 (-)NCBIMhudiblu_PPA_v0panPan3
POMT2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1850,091,861 - 50,133,388 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl850,091,865 - 50,133,442 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha849,779,581 - 49,820,925 (-)NCBI
ROS_Cfam_1.0850,325,424 - 50,366,778 (-)NCBI
UMICH_Zoey_3.1849,988,099 - 50,029,629 (-)NCBI
UNSW_CanFamBas_1.0850,011,110 - 50,052,484 (-)NCBI
UU_Cfam_GSD_1.0850,409,323 - 50,450,667 (-)NCBI
Pomt2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440864025,927,115 - 25,966,356 (+)NCBI
SpeTri2.0NW_0049364886,102,612 - 6,141,842 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
POMT2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl7100,350,460 - 100,417,173 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.17100,350,451 - 100,392,164 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.27106,564,993 - 106,604,420 (+)NCBISscrofa10.2Sscrofa10.2susScr3
POMT2
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12454,519,980 - 54,567,584 (-)NCBI
ChlSab1.1 Ensembl2454,519,754 - 54,567,584 (-)Ensembl
Pomt2
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473424,595,748 - 24,636,845 (+)NCBI

Position Markers
AW046274  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381287,107,160 - 87,107,268UniSTSGRCm38
MGSCv371288,448,110 - 88,448,218UniSTSGRCm37
Celera1288,571,783 - 88,571,891UniSTS
Cytogenetic Map12D2UniSTS
Whitehead/MRC_RH12822.74UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
13207568Tcq14_mtotal cholesterol QTL 14 (mouse)121161000097210000Mouse
4142002Tbqt3_mtibia bone quality traits 3 (mouse)Not determined1235235497109969809Mouse
1357479Splwt1_mspleen weight 1 (mouse)Not determined124164639290920752Mouse
4140993Tglq2b_mtriglyceride QTL 2b (mouse)Not determined125529146189291675Mouse
9850127Tglq6_mtriglyceride QTL6 (mouse)Not determined125529146189291675Mouse
27226728Tibl20_mtibia length 20, 16 week (mouse)125910000093900000Mouse
27226776Tibl6_mtibia length 6, 5 week (mouse)126060000092700000Mouse
10043948Pbft6_mpercent body fat 6 (mouse)Not determined126115865395158653Mouse
1301476Pbwg12_mpostnatal body weight growth 12 (mouse)Not determined126199339095993590Mouse
27226797Scvln19_msacral vertebrae length 2, 16 week (mouse)126210000099500000Mouse
10043895Bw20_mbody weight QTL 20 (mouse)Not determined126226147896261478Mouse
1301046Par3_mpulmonary adenoma resistance 3 (mouse)Not determined126390993497910109Mouse
1301337Cdcs8_mcytokine deficiency colitis susceptibility 8 (mouse)Not determined126464230998642455Mouse
1300633Cdcs7_mcytokine deficiency colitis susceptibility 7 (mouse)Not determined126464230998642455Mouse
14746976Manh73_mmandible shape 73 (mouse)126581035799810357Mouse
27226771Tibl14_mtibia length 14, 10 week (mouse)126830000098800000Mouse
27226793Feml10_mfemur length 10, 5 week (mouse)1268300000113400000Mouse
4141738Tgq23_mtriglyceride QTL 23 (mouse)Not determined72146107106146107Mouse
1301689Skull18_mskull morphology 18 (mouse)Not determined1273920648107920752Mouse
1301926Adip6_madiposity 6 (mouse)Not determined1273920648107920752Mouse
13524842Ppiq10a_mprepulse inhibition QTL 10a (mouse)1277545446111545446Mouse
4142401Egq10_mearly growth QTL 10 (mouse)Not determined80909934113419913Mouse
4141335W6q10_mweight 6 weeks QTL 10 (mouse)Not determined80909934113419913Mouse
4141610Tailaq1_mtail length adjusted QTL 1 (mouse)Not determined80909934113419913Mouse
1357701Lvrq10_mliver weight QTL 10 (mouse)Not determined1280909934113419913Mouse
39128213Lwq23_mliver weight QTL 10 (mouse)1280909934113419913Mouse
13524849Ppiq11a_mprepulse inhibition QTL 11a (mouse)1281022884115022884Mouse
25823169Hrsq8_mhost response to SARS QTL 8, log titer (mouse)1281649471108529109Mouse
13524846Ppiq11_mprepulse inhibition QTL 11 (mouse)1282700137116700137Mouse
1301879Insq10_minsulin QTL 10 (mouse)Not determined1283565816117565965Mouse
1301492Dbsty3_mdiabesity 3 (mouse)Not determined1283565816117565965Mouse
1300883Ath21_matherosclerosis 21 (mouse)Not determined1285995320119995424Mouse
10412156Nociq3_mnociceptive sensitivity inflammatory QTL 3 (mouse)Not determined1286349301114868033Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1000
Count of miRNA genes:552
Interacting mature miRNAs:661
Transcripts:ENSMUST00000037788
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_153415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011244088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_003950038 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC132609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF246235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK043713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK050915 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK076813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK089079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK211754 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY028993 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY090481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY090482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY090483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052045 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC062965 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC079589 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466590 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000037788   ⟹   ENSMUSP00000035260
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1287,106,861 - 87,147,902 (-)Ensembl
RefSeq Acc Id: ENSMUST00000221252
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1287,119,018 - 87,124,862 (-)Ensembl
RefSeq Acc Id: ENSMUST00000222147
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1287,125,113 - 87,147,968 (-)Ensembl
RefSeq Acc Id: ENSMUST00000222634   ⟹   ENSMUSP00000152370
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1287,108,804 - 87,147,474 (-)Ensembl
RefSeq Acc Id: NM_153415   ⟹   NP_700464
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391287,153,635 - 87,194,676 (-)NCBI
GRCm381287,106,861 - 87,147,902 (-)NCBI
MGSCv371288,447,816 - 88,488,852 (-)RGD
Celera1288,571,489 - 88,612,407 (-)RGD
cM Map12 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011244088   ⟹   XP_011242390
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391287,153,635 - 87,194,742 (-)NCBI
GRCm381287,106,861 - 87,147,968 (-)NCBI
Sequence:
RefSeq Acc Id: XR_003950038
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391287,153,635 - 87,194,742 (-)NCBI
GRCm381287,106,861 - 87,147,968 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_700464   ⟸   NM_153415
- UniProtKB: Q8BGQ4 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011242390   ⟸   XM_011244088
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000152370   ⟸   ENSMUST00000222634
RefSeq Acc Id: ENSMUSP00000035260   ⟸   ENSMUST00000037788
Protein Domains
MIR

Promoters
RGD ID:8678878
Promoter ID:EPDNEW_M17470
Type:initiation region
Name:Pomt2_1
Description:Mus musculus protein-O-mannosyltransferase 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381287,147,902 - 87,147,962EPDNEW
RGD ID:6823278
Promoter ID:MM_KWN:12250
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Kidney,   Liver,   MEF_B4,   MEF_B6
Transcripts:NM_153415,   UC007OIK.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361288,488,536 - 88,489,777 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444430 AgrOrtholog
Ensembl Genes ENSMUSG00000034126 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000035260 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000152370 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000037788 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000222634 UniProtKB/Swiss-Prot
InterPro GlyclTrfase_39-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_trans_39/83 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MIR_motif UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PMT_4TMC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:217734 UniProtKB/Swiss-Prot
MGD MGI:2444430 ENTREZGENE
NCBI Gene 217734 ENTREZGENE
PANTHER PTHR10050 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PMT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PMT_4TMC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pomt2 PhenoGen
PROSITE MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART MIR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF82109 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt POMT2_MOUSE UniProtKB/Swiss-Prot
  Q6P5C1_MOUSE UniProtKB/TrEMBL
  Q8BGQ4 ENTREZGENE
UniProt Secondary Q8R4Z0 UniProtKB/Swiss-Prot