Defb114 (defensin beta 114) - Rat Genome Database

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Gene: Defb114 (defensin beta 114) Ictidomys tridecemlineatus
Analyze
Symbol: Defb114
Name: defensin beta 114
RGD ID: 13134473
Description: ENCODES a protein that exhibits lipopolysaccharide binding (ortholog); INVOLVED IN innate immune response (ortholog); negative regulation of lipopolysaccharide-mediated signaling pathway (ortholog); negative regulation of tumor necrosis factor production (ortholog); ASSOCIATED WITH genetic disease (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: beta-defensin 114
RGD Orthologs
Human
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: SpeTri2.0 - Squirrel SpeTri2.0 Assembly
Position:
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494653,302,417 - 53,309,040 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647610,651,162 - 10,657,785 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References
Additional References at PubMed
PMID:22301074  


Genomics

Comparative Map Data
Defb114
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494653,302,417 - 53,309,040 (-)NCBIHiC_Itri_2
SpeTri2.0NW_00493647610,651,162 - 10,657,785 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DEFB114
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38649,960,249 - 49,964,164 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl649,960,249 - 49,964,164 (-)EnsemblGRCh38hg38GRCh38
GRCh37649,927,962 - 49,931,877 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36650,035,964 - 50,039,777 (-)NCBINCBI36Build 36hg18NCBI36
Celera651,484,077 - 51,487,890 (-)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef649,659,499 - 49,663,312 (-)NCBIHuRef
CHM1_1649,930,757 - 49,934,570 (-)NCBICHM1_1
T2T-CHM13v2.0649,803,143 - 49,807,058 (-)NCBIT2T-CHM13v2.0
DEFB114
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2564,441,406 - 64,445,321 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1660,307,208 - 60,311,124 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0649,527,541 - 49,531,451 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1650,787,203 - 50,791,015 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl650,787,203 - 50,791,015 (-)Ensemblpanpan1.1panPan2
DEFB114
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11217,771,204 - 17,781,535 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1217,771,246 - 17,781,504 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1217,667,335 - 17,677,666 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01218,263,171 - 18,276,076 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1218,265,775 - 18,276,010 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11217,775,033 - 17,787,937 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01217,880,928 - 17,893,828 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01218,011,296 - 18,024,201 (-)NCBIUU_Cfam_GSD_1.0
DEFB114
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl743,982,233 - 43,993,156 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1743,982,219 - 43,993,156 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2750,374,500 - 50,383,719 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DEFB114
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366604449,927,693 - 49,931,924 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_021721768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAESOR010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: XM_021721768   ⟹   XP_021577443
Type: CODING
Position:
Squirrel AssemblyChrPosition (strand)Source
HiC_Itri_2NW_02440494653,302,417 - 53,309,040 (-)NCBI
SpeTri2.0NW_00493647610,651,162 - 10,657,785 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_021577443 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein KAG3289612 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: XP_021577443   ⟸   XM_021721768
- Sequence:


Additional Information

Database Acc Id Source(s)
NCBI Gene Defb114 ENTREZGENE