Irak4 (interleukin-1 receptor-associated kinase 4) - Rat Genome Database

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Gene: Irak4 (interleukin-1 receptor-associated kinase 4) Mus musculus
Analyze
Symbol: Irak4
Name: interleukin-1 receptor-associated kinase 4
RGD ID: 1313253
MGI Page MGI
Description: Enables interleukin-1 receptor binding activity. Acts upstream of or within cytokine-mediated signaling pathway. Predicted to be located in extracellular space. Predicted to be active in several cellular components, including cell surface; nucleus; and plasma membrane. Is expressed in aorta-gonad-mesonephros; central nervous system; liver; retina; and ureteric trunk. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human IRAK4 (interleukin 1 receptor associated kinase 4).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 8430405M07Rik; 9330209D03Rik; IRA; IRAK-4; NY-REN; NY-REN-64
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391594,441,495 - 94,466,198 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1594,441,524 - 94,479,696 (+)EnsemblGRCm39 Ensembl
GRCm381594,543,613 - 94,568,317 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1594,543,643 - 94,581,815 (+)EnsemblGRCm38mm10GRCm38
MGSCv371594,374,091 - 94,398,748 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361594,371,900 - 94,396,212 (+)NCBIMGSCv36mm8
Celera1596,687,848 - 96,713,099 (+)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1548.55NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Protective effect of diallyl trisulfide on liver in rats with sepsis and the mechanism. Chen H, etal., J Huazhong Univ Sci Technolog Med Sci. 2012 Oct;32(5):657-62. doi: 10.1007/s11596-012-1013-7.
2. Caspase-1-processed interleukins in hyperoxia-induced cell death in the developing brain. Felderhoff-Mueser U, etal., Ann Neurol. 2005 Jan;57(1):50-9.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Pathogen recognition by the innate immune system. Kumar H, etal., Int Rev Immunol. 2011 Feb;30(1):16-34.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. MGD IEA MGD IEA
7. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
8. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
9. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Picard C, etal., Science. 2003 Mar 28;299(5615):2076-9. Epub 2003 Mar 13.
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Comparative analysis of apoptosis and inflammation genes of mice and humans. Reed JC, etal., Genome Res 2003 Jun;13(6B):1376-88.
13. Mouse MP Annotation Import Pipeline RGD automated import pipeline
14. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
15. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
16. TLR-4, IL-1R and TNF-R signaling to NF-kappaB: variations on a common theme. Verstrepen L, etal., Cell Mol Life Sci. 2008 Oct;65(19):2964-78.
17. Interleukin-1 (IL-1) pathway. Weber A, etal., Sci Signal. 2010 Jan 19;3(105):cm1. doi: 10.1126/scisignal.3105cm1.
18. Interleukin-1 receptor associated kinases-1/4 inhibition protects against acute hypoxia/ischemia-induced neuronal injury in vivo and in vitro. Yang YF, etal., Neuroscience. 2011 Nov 24;196:25-34. doi: 10.1016/j.neuroscience.2011.08.059. Epub 2011 Sep 10.
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11544199   PMID:11923871   PMID:11960013   PMID:12477932   PMID:12538665   PMID:12682231   PMID:12935356   PMID:14634120   PMID:15292196  
PMID:15489334   PMID:16040976   PMID:16141072   PMID:16141073   PMID:16177054   PMID:16179420   PMID:16306937   PMID:16574867   PMID:16602821   PMID:17178921   PMID:17337443   PMID:17360955  
PMID:17470642   PMID:17485511   PMID:17507369   PMID:17548806   PMID:17974599   PMID:18190779   PMID:18266302   PMID:18286567   PMID:18287559   PMID:18378686   PMID:18510099   PMID:18772134  
PMID:18794297   PMID:18805969   PMID:18806225   PMID:18992325   PMID:19019092   PMID:19167362   PMID:19378012   PMID:19434478   PMID:19454718   PMID:19479877   PMID:19542468   PMID:19570822  
PMID:19770394   PMID:19864601   PMID:21045126   PMID:21160042   PMID:21267068   PMID:21278342   PMID:21844234   PMID:21873635   PMID:21934070   PMID:22011580   PMID:22550345   PMID:23027530  
PMID:23100432   PMID:23209321   PMID:23255009   PMID:23264652   PMID:23376919   PMID:23695305   PMID:24030499   PMID:24043892   PMID:24379360   PMID:24529375   PMID:24588661   PMID:24642374  
PMID:24717937   PMID:25404736   PMID:25918710   PMID:26011644   PMID:26732763   PMID:26831104   PMID:27113764   PMID:27439514   PMID:27807192   PMID:27840174   PMID:27869651   PMID:28137874  
PMID:28295231   PMID:28658630   PMID:29749650   PMID:30076215   PMID:30108181   PMID:30391544   PMID:31527315   PMID:32487715   PMID:33956941   PMID:34298177   PMID:35022428   PMID:35271824  
PMID:35339728  


Genomics

Comparative Map Data
Irak4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391594,441,495 - 94,466,198 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1594,441,524 - 94,479,696 (+)EnsemblGRCm39 Ensembl
GRCm381594,543,613 - 94,568,317 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1594,543,643 - 94,581,815 (+)EnsemblGRCm38mm10GRCm38
MGSCv371594,374,091 - 94,398,748 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361594,371,900 - 94,396,212 (+)NCBIMGSCv36mm8
Celera1596,687,848 - 96,713,099 (+)NCBICelera
Cytogenetic Map15E3NCBI
cM Map1548.55NCBI
IRAK4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381243,758,951 - 43,789,541 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1243,758,944 - 43,798,307 (+)EnsemblGRCh38hg38GRCh38
GRCh371244,152,754 - 44,183,344 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361242,439,047 - 42,468,166 (+)NCBINCBI36Build 36hg18NCBI36
Build 341242,439,046 - 42,468,164NCBI
Celera1242,955,135 - 42,985,734 (+)NCBICelera
Cytogenetic Map12q12NCBI
HuRef1241,181,921 - 41,210,557 (+)NCBIHuRef
CHM1_11244,117,733 - 44,148,328 (+)NCBICHM1_1
T2T-CHM13v2.01243,717,649 - 43,748,266 (+)NCBIT2T-CHM13v2.0
Irak4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr87127,561,777 - 127,588,762 (+)NCBIGRCr8
mRatBN7.27125,682,502 - 125,708,294 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7125,682,488 - 125,717,837 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx7127,467,774 - 127,493,636 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.07129,693,680 - 129,719,540 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.07129,594,914 - 129,620,776 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.07135,803,723 - 135,831,006 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl7135,803,698 - 135,832,652 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.07135,461,296 - 135,487,468 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.47133,055,185 - 133,081,614 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.17133,131,009 - 133,157,870 (+)NCBI
Celera7122,072,276 - 122,098,055 (+)NCBICelera
Cytogenetic Map7q35NCBI
Irak4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555003,010,505 - 3,051,986 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555003,010,505 - 3,039,090 (+)NCBIChiLan1.0ChiLan1.0
IRAK4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21050,383,896 - 50,414,571 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11250,380,653 - 50,411,344 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01244,941,862 - 44,972,520 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11245,810,917 - 45,841,492 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1245,810,917 - 45,841,492 (-)Ensemblpanpan1.1panPan2
IRAK4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12710,313,782 - 10,340,652 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2710,314,187 - 10,340,682 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2735,967,589 - 35,995,188 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02710,502,276 - 10,529,893 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2710,502,248 - 10,529,935 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12710,313,739 - 10,341,482 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02710,348,090 - 10,375,692 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02736,209,066 - 36,236,651 (+)NCBIUU_Cfam_GSD_1.0
Irak4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494570,892,828 - 70,916,756 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365122,248,146 - 2,272,002 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365122,248,116 - 2,272,002 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
IRAK4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl574,834,600 - 74,859,344 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1574,842,184 - 74,858,125 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2577,646,762 - 77,672,328 (+)NCBISscrofa10.2Sscrofa10.2susScr3
IRAK4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11139,967,738 - 39,999,969 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1139,977,636 - 39,999,847 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037206,510,824 - 206,545,598 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Irak4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248168,778,299 - 8,802,883 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248168,783,075 - 8,808,734 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Irak4
1000 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1100
Count of miRNA genes:640
Interacting mature miRNAs:791
Transcripts:ENSMUST00000074936, ENSMUST00000109248, ENSMUST00000138306
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884442Sklq6_mskull length QTL 6, 5 week (mouse)156129481100797881Mouse
1357526Hyplip2_mhyperlipidemia 2 (mouse)Not determined1512402203102896555Mouse
26884425Cvht2_mcranial vault height 2, 5 week (mouse)1528800146102008435Mouse
1558985Eae32_mexperimental allergic encephalomyelitis susceptibility 32 (mouse)Not determined1532578416103425899Mouse
26884402Cvht9_mcranial vault height 9, 16 week (mouse)154216339695497881Mouse
26884397Humsd5_mhumerus midshaft diameter 5, 10 week (mouse)154836339698397881Mouse
26884399Humsd1_mhumerus midshaft diameter 1, 5 week (mouse)1548363396101708435Mouse
1302074Bmd4_mbone mineral density 4 (mouse)Not determined1556186708103425899Mouse
12880420V25Dq8_mvitamin D inactive form serum level QTL 8 (mouse)156158420095584200Mouse
1301601Faq9_mfluctuating asymmetry QTL 9 (mouse)Not determined156316390397163995Mouse
1302197Bhr2_mbronchial hyperresponsiveness 2 (mouse)Not determined1564306334103425899Mouse
4141135Cia35_mcollagen induced arthritis 35 (mouse)Not determined156481182698811946Mouse
1301119Drb7_mdopamine receptor binding 7 (mouse)Not determined156533657899341028Mouse
1301171Brm2_mbrachyury modifier 2 (mouse)Not determined156552537699525499Mouse
4141921Pstc3_mperiosteal circumference 3 (mouse)Not determined1567270698101270847Mouse
1300627Sluc26_msusceptibility to lung cancer 26 (mouse)Not determined1570345653104073951Mouse
1300648Dbsty4_mdiabesity 4 (mouse)Not determined1570349271104073951Mouse
1300726Pitm4_mprion incubation time 4 (mouse)Not determined1570349271104073951Mouse
14747011Mancz13_mmandible centroid size 13 (mouse)1572382669104073951Mouse
12791003Aath8_maortic arch atherosclerosis 8 (mouse)1573430144104073951Mouse
1300851Heal4_mwound healing/regeneration 4 (mouse)Not determined1577527592104073951Mouse
4142060W3q6_mweight 3 weeks QTL 6 (mouse)Not determined78601103102901704Mouse
1357894Epfpq3_mepididymal fat percentage QTL 3 (mouse)Not determined1578601103102901704Mouse
14928306Manh79_mmandible shape 79 (mouse)1578847557104073951Mouse
12880411V125Dq11_mvitamin D active form serum level QTL 11 (mouse)1578897881104073951Mouse
10402490Dipa5_mdrug induced psychomotor activation 5 (mouse)Not determined1579163411104073951Mouse
4141897Imrfq2_mimmune response to Factor IX QTL 2 (mouse)Not determined79908940104073951Mouse
1301284Cosz3_mcocaine seizure 3 (mouse)Not determined1580313634104073951Mouse
4141902Cia37_mcollagen induced arthritis 37 (mouse)Not determined1580884933104073951Mouse
1300974Pgia9_mproteoglycan induced arthritis 9 (mouse)Not determined1580884933104073951Mouse
4141511Gdcr1_mglycerolphosphate dehydrogenase regulator 1 (mouse)Not determined82615474104073951Mouse
11530037Sluc34a_msusceptibility to lung cancer 34a (mouse)1585896437104073951Mouse
11530038Sluc34b_msusceptibility to lung cancer 34b (mouse)1585896437104073951Mouse
1357614Bmca_mbile mucin accumulation (mouse)Not determined1585896437104073951Mouse
1301918Skull22_mskull morphology 22 (mouse)Not determined1585901546104073951Mouse
4141581Dshv1_mdorsal hippocampal volume 1 (mouse)Not determined92788640103425899Mouse

Markers in Region
Irak4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map15F1UniSTS
cM Map15 UniSTS


Expression


Sequence


RefSeq Acc Id: ENSMUST00000074936   ⟹   ENSMUSP00000074471
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1594,441,524 - 94,466,187 (+)Ensembl
GRCm38.p6 Ensembl1594,543,643 - 94,568,306 (+)Ensembl
RefSeq Acc Id: ENSMUST00000109248   ⟹   ENSMUSP00000104871
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1594,441,553 - 94,479,696 (+)Ensembl
GRCm38.p6 Ensembl1594,543,672 - 94,581,815 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138306
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1594,441,534 - 94,454,834 (+)Ensembl
GRCm38.p6 Ensembl1594,543,653 - 94,556,953 (+)Ensembl
RefSeq Acc Id: NM_029926   ⟹   NP_084202
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391594,441,541 - 94,466,198 (+)NCBI
GRCm381594,543,660 - 94,568,317 (+)NCBI
MGSCv371594,374,091 - 94,398,748 (+)RGD
Celera1596,687,848 - 96,713,099 (+)RGD
cM Map15 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_011245645   ⟹   XP_011243947
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391594,441,495 - 94,454,469 (+)NCBI
GRCm381594,543,613 - 94,556,589 (+)NCBI
Sequence:
RefSeq Acc Id: NP_084202   ⟸   NM_029926
- UniProtKB: Q80WW1 (UniProtKB/Swiss-Prot),   Q8R4K2 (UniProtKB/Swiss-Prot),   Q3USX5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011243947   ⟸   XM_011245645
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000104871   ⟸   ENSMUST00000109248
RefSeq Acc Id: ENSMUSP00000074471   ⟸   ENSMUST00000074936
Protein Domains
Death   Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R4K2-F1-model_v2 AlphaFold Q8R4K2 1-459 view protein structure

Promoters
RGD ID:6826114
Promoter ID:MM_KWN:19516
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000109247,   ENSMUST00000109248,   NM_029926_IRAK4,   NM_172437_PUS7L,   OTTMUST00000040437,   OTTMUST00000040439,   OTTMUST00000057018,   OTTMUST00000057019,   OTTMUST00000057020
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361594,373,616 - 94,374,222 (+)MPROMDB
RGD ID:8684820
Promoter ID:EPDNEW_M20440
Type:initiation region
Name:Irak4_1
Description:Mus musculus interleukin-1 receptor-associated kinase 4 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381594,543,629 - 94,543,689EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2182474 AgrOrtholog
Ensembl Genes ENSMUSG00000059883 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000074936 ENTREZGENE
  ENSMUST00000074936.10 UniProtKB/Swiss-Prot
  ENSMUST00000109248.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.533.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro DEATH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Death_domain UniProtKB/TrEMBL
  IRAK4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IRAK4_Death UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:266632 UniProtKB/Swiss-Prot
MGD MGI:2182474 ENTREZGENE
NCBI Gene 266632 ENTREZGENE
PANTHER INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE UniProtKB/TrEMBL
  INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE 4 UniProtKB/TrEMBL
  OS01G0253100 PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROLINE-RICH RECEPTOR-LIKE PROTEIN KINASE PERK8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Death UniProtKB/TrEMBL
  Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Irak4 PhenoGen
PIRSF IRAK4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47986 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt IRAK4_MOUSE UniProtKB/Swiss-Prot
  Q3USX5 ENTREZGENE, UniProtKB/TrEMBL
  Q80WW1 ENTREZGENE
  Q8R4K2 ENTREZGENE
  Q9D250_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q80WW1 UniProtKB/Swiss-Prot