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Gene: Abce1 (ATP-binding cassette, sub-family E (OABP), member 1) Mus musculus
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Symbol: Abce1
Name: ATP-binding cassette, sub-family E (OABP), member 1
Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ATP-binding cassette sub-family E member 1; ATP-binding cassette, subfamily E, member 1; C79080; Oabp; ribonuclease 4 inhibitor; ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent) inhibitor; RLI; RNase L inhibitor; Rnaseli; RNS41; RNS4I; RNS4l (Eye)
Orthologs:
Homo sapiens (human) : ABCE1 (ATP binding cassette subfamily E member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Abce1 (ATP binding cassette subfamily E member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Abce1 (ATP binding cassette subfamily E member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ABCE1 (ATP binding cassette subfamily E member 1)
Canis lupus familiaris (dog) : ABCE1 (ATP binding cassette subfamily E member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Abce1 (ATP binding cassette subfamily E member 1)
Sus scrofa (pig) : ABCE1 (ATP binding cassette subfamily E member 1)
more info ...
Related Pseudogenes: Gm19061   Gm6640  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38879,683,442 - 79,711,740 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37882,207,341 - 82,235,639 (-)NCBIGRCm37mm9NCBIm37
MGSCv36882,579,717 - 82,607,693 (-)NCBImm8
Celera883,959,260 - 83,987,564 (-)NCBICelera
Cytogenetic Map8 C1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Abce1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313250
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-02-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.