Ccdc174 (coiled-coil domain containing 174) - Rat Genome Database
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Gene: Ccdc174 (coiled-coil domain containing 174) Mus musculus
Analyze
Symbol: Ccdc174
Name: coiled-coil domain containing 174
RGD ID: 1313126
MGI Page MGI
Description: Orthologous to human CCDC174 (coiled-coil domain containing 174); INTERACTS WITH 1,2-dimethylhydrazine; 4-hydroxyphenyl retinamide; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C130022K22Rik; coiled-coil domain-containing protein 174; hypothetical protein LOC232236; uncharacterized protein C3orf19 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39691,819,983 - 91,876,830 (+)NCBIGRCm39mm39
GRCm39 Ensembl691,855,034 - 91,876,824 (+)Ensembl
GRCm38691,843,154 - 91,899,849 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl691,878,053 - 91,899,843 (+)EnsemblGRCm38mm10GRCm38
MGSCv37691,828,047 - 91,849,842 (+)NCBIGRCm37mm9NCBIm37
MGSCv36691,843,576 - 91,865,352 (+)NCBImm8
Celera693,772,237 - 93,794,129 (+)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleoplasm  (ISO)
nucleus  (ISO)

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12520002   PMID:14610273   PMID:15489334   PMID:16141072   PMID:16141073  
PMID:21267068  


Genomics

Comparative Map Data
Ccdc174
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39691,819,983 - 91,876,830 (+)NCBIGRCm39mm39
GRCm39 Ensembl691,855,034 - 91,876,824 (+)Ensembl
GRCm38691,843,154 - 91,899,849 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl691,878,053 - 91,899,843 (+)EnsemblGRCm38mm10GRCm38
MGSCv37691,828,047 - 91,849,842 (+)NCBIGRCm37mm9NCBIm37
MGSCv36691,843,576 - 91,865,352 (+)NCBImm8
Celera693,772,237 - 93,794,129 (+)NCBICelera
Cytogenetic Map6D1NCBI
CCDC174
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl314,651,746 - 14,672,659 (+)EnsemblGRCh38hg38GRCh38
GRCh38314,651,762 - 14,672,659 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37314,693,269 - 14,714,162 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36314,668,257 - 14,689,170 (+)NCBINCBI36hg18NCBI36
Build 34314,668,272 - 14,689,164NCBI
Celera314,631,500 - 14,652,414 (+)NCBI
Cytogenetic Map3p25.1NCBI
HuRef314,629,033 - 14,649,937 (+)NCBIHuRef
CHM1_1314,644,329 - 14,665,233 (+)NCBICHM1_1
Ccdc174
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24124,392,183 - 124,419,035 (+)NCBI
Rnor_6.0 Ensembl4123,760,743 - 123,787,528 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04123,760,708 - 123,787,529 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04189,474,030 - 189,501,580 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44126,074,136 - 126,100,614 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14126,318,976 - 126,345,455 (+)NCBI
Celera4113,310,952 - 113,336,955 (+)NCBICelera
Cytogenetic Map4q34NCBI
Ccdc174
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542917,201,027 - 17,218,726 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542917,201,563 - 17,218,726 (+)NCBIChiLan1.0ChiLan1.0
CCDC174
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1314,913,345 - 14,934,261 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl314,913,328 - 14,934,261 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0314,574,082 - 14,595,025 (+)NCBIMhudiblu_PPA_v0panPan3
CCDC174
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl204,753,542 - 4,776,032 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1204,753,433 - 4,778,446 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Ccdc174
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_004936602360,048 - 374,960 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CCDC174
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1369,895,324 - 69,915,655 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11369,898,803 - 69,918,896 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CCDC174
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12250,595,136 - 50,616,165 (+)NCBI
ChlSab1.1 Ensembl2250,595,175 - 50,614,691 (+)Ensembl
Ccdc174
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248721,176,317 - 1,193,344 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
1301687Mnic2_mmacronutrient intake (mouse)Not determined686806805113544602Mouse
1301744Hdlq11_mHDL QTL 11 (mouse)Not determined687503360121503555Mouse
1301262Gasa3_mgastritis type A susceptibility locus 3 (mouse)Not determined689005405123005603Mouse
1301244Ichs_mimmediate cutaneous hypersensitivity QTL (mouse)Not determined690795610124795846Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:641
Count of miRNA genes:415
Interacting mature miRNAs:468
Transcripts:ENSMUST00000037783, ENSMUST00000136090, ENSMUST00000138868, ENSMUST00000139240, ENSMUST00000147188, ENSMUST00000149546, ENSMUST00000151378
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_172730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030255348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036166056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC168852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK039818 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK051852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK081505 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK155581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK156259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC016607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC038871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY624970 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000037783   ⟹   ENSMUSP00000049280
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl691,878,053 - 91,899,843 (+)Ensembl
RefSeq Acc Id: ENSMUST00000136090   ⟹   ENSMUSP00000146317
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl691,878,053 - 91,899,843 (+)Ensembl
RefSeq Acc Id: ENSMUST00000138868
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl691,878,053 - 91,884,987 (+)Ensembl
RefSeq Acc Id: ENSMUST00000139240
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl691,878,075 - 91,888,317 (+)Ensembl
RefSeq Acc Id: ENSMUST00000147188
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl691,892,347 - 91,895,293 (+)Ensembl
RefSeq Acc Id: ENSMUST00000149546
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl691,878,072 - 91,880,511 (+)Ensembl
RefSeq Acc Id: ENSMUST00000151378
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl691,892,804 - 91,895,339 (+)Ensembl
RefSeq Acc Id: NM_172730   ⟹   NP_766318
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,855,034 - 91,876,829 (+)NCBI
GRCm38691,878,053 - 91,899,848 (+)NCBI
MGSCv37691,828,047 - 91,849,842 (+)RGD
Celera693,772,237 - 93,794,129 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030255347   ⟹   XP_030111207
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,819,983 - 91,876,830 (+)NCBI
GRCm38691,843,154 - 91,899,849 (+)NCBI
Sequence:
RefSeq Acc Id: XM_030255348   ⟹   XP_030111208
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,854,891 - 91,876,830 (+)NCBI
GRCm38691,877,902 - 91,899,849 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036166055   ⟹   XP_036021948
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,820,827 - 91,876,830 (+)NCBI
RefSeq Acc Id: XM_036166056   ⟹   XP_036021949
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39691,834,991 - 91,876,830 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_766318   ⟸   NM_172730
- UniProtKB: Q3U155 (UniProtKB/Swiss-Prot),   A0A0R4J0L8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030111207   ⟸   XM_030255347
- Peptide Label: isoform X1
RefSeq Acc Id: XP_030111208   ⟸   XM_030255348
- Peptide Label: isoform X3
RefSeq Acc Id: ENSMUSP00000049280   ⟸   ENSMUST00000037783
RefSeq Acc Id: ENSMUSP00000146317   ⟸   ENSMUST00000136090
RefSeq Acc Id: XP_036021948   ⟸   XM_036166055
- Peptide Label: isoform X1
RefSeq Acc Id: XP_036021949   ⟸   XM_036166056
- Peptide Label: isoform X2

Promoters
RGD ID:6839017
Promoter ID:MM_KWN:46932
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_172730,   OTTMUST00000058029,   OTTMUST00000058031,   OTTMUST00000058032,   UC009CYJ.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36691,827,774 - 91,828,274 (+)MPROMDB
RGD ID:6890462
Promoter ID:EPDNEW_M8682
Type:initiation region
Name:Ccdc174_1
Description:Mus musculus coiled-coil domain containing 174 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38691,878,073 - 91,878,133EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2444652 AgrOrtholog
Ensembl Genes ENSMUSG00000034083 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000049280 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000146317 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000037783 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000136090 UniProtKB/TrEMBL
InterPro DUF4078 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:232236 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:2444652 ENTREZGENE
NCBI Gene 232236 ENTREZGENE
Pfam DUF4078 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Ccdc174 PhenoGen
UniProt A0A0R4J0L8 ENTREZGENE, UniProtKB/TrEMBL
  A0A0U1RQA8_MOUSE UniProtKB/TrEMBL
  A0PJ68_MOUSE UniProtKB/TrEMBL
  CC174_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8C4Q1_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q80XC8 UniProtKB/Swiss-Prot
  Q8CA20 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-10-09 Ccdc174  coiled-coil domain containing 174  C130022K22Rik  RIKEN cDNA C130022K22 gene  Symbol and/or name change 5135510 APPROVED