Tma16 (translation machinery associated 16) - Rat Genome Database
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Gene: Tma16 (translation machinery associated 16) Mus musculus
Analyze
Symbol: Tma16
Name: translation machinery associated 16
RGD ID: 1313122
MGI Page MGI
Description: Predicted to localize to nucleolus and nucleoplasm. Is expressed in liver lobe and urethra. Orthologous to human TMA16 (translation machinery associated 16 homolog); INTERACTS WITH 4,4'-sulfonyldiphenol; carbon nanotube; dioxygen.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1810029B16Rik; hypothetical protein LOC66282; translation machinery associated 16 homolog; translation machinery-associated protein 16; UPF0534 protein C4orf43 homolog
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm5251   Gm8550  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39866,928,995 - 66,939,182 (-)NCBIGRCm39mm39
GRCm38866,476,343 - 66,486,530 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl866,473,118 - 66,486,530 (-)EnsemblGRCm38mm10GRCm38
MGSCv37869,000,245 - 69,010,406 (-)NCBIGRCm37mm9NCBIm37
MGSCv36869,405,335 - 69,415,496 (-)NCBImm8
Celera869,032,446 - 69,042,622 (-)NCBICelera
Cytogenetic Map8B3.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nucleolus  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA)

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12904583   PMID:14610273   PMID:16141072   PMID:16141073   PMID:21267068  
PMID:21677750   PMID:21873635   PMID:32325033  


Genomics

Comparative Map Data
Tma16
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39866,928,995 - 66,939,182 (-)NCBIGRCm39mm39
GRCm38866,476,343 - 66,486,530 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl866,473,118 - 66,486,530 (-)EnsemblGRCm38mm10GRCm38
MGSCv37869,000,245 - 69,010,406 (-)NCBIGRCm37mm9NCBIm37
MGSCv36869,405,335 - 69,415,496 (-)NCBImm8
Celera869,032,446 - 69,042,622 (-)NCBICelera
Cytogenetic Map8B3.1NCBI
TMA16
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4163,494,442 - 163,520,539 (+)EnsemblGRCh38hg38GRCh38
GRCh384163,494,690 - 163,520,539 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374164,415,673 - 164,441,691 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364164,635,123 - 164,661,141 (+)NCBINCBI36hg18NCBI36
Celera4161,747,938 - 161,773,962 (+)NCBI
Cytogenetic Map4q32.2NCBI
HuRef4160,169,554 - 160,195,568 (+)NCBIHuRef
CHM1_14164,392,123 - 164,418,141 (+)NCBICHM1_1
Tma16
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01624,978,429 - 24,997,286 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1624,978,527 - 24,997,006 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01624,862,100 - 24,880,952 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41624,948,510 - 24,964,415 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11624,948,468 - 24,964,413 (+)NCBI
Celera1623,353,072 - 23,368,380 (+)NCBICelera
Cytogenetic Map16p14NCBI
Tma16
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540341,493,413 - 41,510,183 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540341,493,624 - 41,510,162 (-)NCBIChiLan1.0ChiLan1.0
TMA16
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14167,549,482 - 167,575,665 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4167,549,943 - 167,575,167 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04155,760,991 - 155,787,410 (+)NCBIMhudiblu_PPA_v0panPan3
TMA16
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1559,719,633 - 59,750,553 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11559,720,318 - 59,751,236 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Tma16
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365552,100,958 - 2,118,340 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMA16
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl852,343,233 - 52,375,044 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1852,343,207 - 52,371,367 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2855,470,791 - 55,498,960 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMA16
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl7109,944,567 - 109,970,593 (+)Ensembl
ChlSab1.17109,944,195 - 109,970,599 (+)NCBI
Tma16
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475813,326,356 - 13,345,246 (-)NCBI

Position Markers
Avpr1b  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map10D1UniSTS
Cytogenetic Map13D1UniSTS
Cytogenetic Map18D3UniSTS
Cytogenetic MapXF1UniSTS
Cytogenetic Map7CUniSTS
Cytogenetic Map13B2UniSTS
Cytogenetic Map4D1UniSTS
Cytogenetic Map10A1UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map17A1UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map7F1UniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map7F2UniSTS
Cytogenetic Map8E1UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map10B5.1UniSTS
Cytogenetic Map1E4UniSTS
Cytogenetic Map7E3UniSTS
Cytogenetic Map1A2UniSTS
Cytogenetic Map3F2.1UniSTS
Cytogenetic Map16A3UniSTS
Cytogenetic MapXA1.1UniSTS
Cytogenetic Map3F2.2UniSTS
Cytogenetic Map6E3UniSTS
Cytogenetic Map4C3UniSTS
Cytogenetic Map18B3UniSTS
cM Map1 UniSTS
px-38e3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D1UniSTS
Cytogenetic Map18B3UniSTS
Cytogenetic Map18D3UniSTS
Cytogenetic Map5B3UniSTS
Cytogenetic Map17B3UniSTS
Cytogenetic Map4C7UniSTS
Cytogenetic Map13C1UniSTS
Cytogenetic Map16B5UniSTS
Cytogenetic Map4D2.3UniSTS
Cytogenetic Map8B3.3UniSTS
Cytogenetic Map1H4UniSTS
Cytogenetic Map7F2UniSTS
Cytogenetic Map10D2UniSTS
Cytogenetic Map2G3UniSTS
Cytogenetic Map14BUniSTS
Cytogenetic Map11B5UniSTS
Cytogenetic MapYA1UniSTS
Cytogenetic Map11A3.2UniSTS
Cytogenetic Map3A1UniSTS
Cytogenetic Map13C3UniSTS
Cytogenetic Map1H6UniSTS
Cytogenetic Map5B2UniSTS
Cytogenetic Map19C3UniSTS
Cytogenetic Map10D1UniSTS
Cytogenetic Map10A1UniSTS
cM Map1060.0UniSTS
cM Map1106.6UniSTS
cM Map1936.5UniSTS
cM Map520.0UniSTS
cM Map1340.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1301936Trigq2_mtriglyceride QTL 2 (mouse)Not determined83383736267837502Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:329
Count of miRNA genes:269
Interacting mature miRNAs:297
Transcripts:ENSMUST00000026681, ENSMUST00000143972, ENSMUST00000145787
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000026681   ⟹   ENSMUSP00000026681
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl866,473,118 - 66,486,519 (-)Ensembl
RefSeq Acc Id: ENSMUST00000143972   ⟹   ENSMUSP00000148586
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl866,474,330 - 66,486,497 (-)Ensembl
RefSeq Acc Id: ENSMUST00000145787
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl866,482,395 - 66,486,530 (-)Ensembl
RefSeq Acc Id: ENSMUST00000213036
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl866,484,735 - 66,486,521 (-)Ensembl
RefSeq Acc Id: NM_001357208   ⟹   NP_001344137
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39866,928,995 - 66,939,182 (-)NCBI
GRCm38866,476,343 - 66,486,530 (-)NCBI
Sequence:
RefSeq Acc Id: NM_025465   ⟹   NP_079741
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39866,928,995 - 66,939,182 (-)NCBI
GRCm38866,476,343 - 66,486,530 (-)NCBI
MGSCv37869,000,245 - 69,010,406 (-)RGD
Celera869,032,446 - 69,042,622 (-)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_079741   ⟸   NM_025465
- Peptide Label: isoform 1
- UniProtKB: Q9CR02 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001344137   ⟸   NM_001357208
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000026681   ⟸   ENSMUST00000026681
RefSeq Acc Id: ENSMUSP00000148586   ⟸   ENSMUST00000143972

Promoters
RGD ID:8667185
Promoter ID:EPDNEW_M11624
Type:initiation region
Name:Tma16_1
Description:Mus musculus translation machinery associated 16 , transcriptvariant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38866,486,526 - 66,486,586EPDNEW
RGD ID:6842496
Promoter ID:MM_KWN:54559
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000076101,   OTTMUST00000076103,   UC009LVP.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36869,010,186 - 69,010,686 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913532 AgrOrtholog
Ensembl Genes ENSMUSG00000025591 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000026681 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000148586 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000026681 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000143972 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1440.170 UniProtKB/Swiss-Prot
InterPro Tma16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tma16_sf UniProtKB/Swiss-Prot
KEGG Report mmu:66282 UniProtKB/Swiss-Prot
MGD MGI:1913532 ENTREZGENE
NCBI Gene 66282 ENTREZGENE
PANTHER PTHR13349 UniProtKB/Swiss-Prot
Pfam Tma16 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tma16 PhenoGen
UniGene Mm.294985 ENTREZGENE
UniProt A0A1D5RM14_MOUSE UniProtKB/TrEMBL
  Q8BPZ6_MOUSE UniProtKB/TrEMBL
  Q9CR02 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q05DD8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 Tma16  translation machinery associated 16    translation machinery associated 16 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED
2012-09-19 Tma16  translation machinery associated 16 homolog (S. cerevisiae)  1810029B16Rik  RIKEN cDNA 1810029B16 gene  Symbol and/or name change 5135510 APPROVED