Foxb1 (forkhead box B1) - Rat Genome Database

Name: Foxb1
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Foxb1 (forkhead box B1) Mus musculus

Analyze

Symbol:

Foxb1

Name:

forkhead box B1

RGD ID:

1313113

MGI Page

MGI

Description:

Enables sequence-specific DNA binding activity. Involved in several processes, including mammary gland development; nervous system development; and visual learning. Acts upstream of or within spinal cord development; thalamus development; and urogenital system development. Located in nucleus. Is expressed in several structures, including central nervous system; embryo ectoderm; limb; paraxial mesenchyme; and tail bud. Orthologous to human FOXB1 (forkhead box B1).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

C43; Fkh5; forkhead box B1a; forkhead box B1b; forkhead box protein B1; Foxb; Foxb1a; Foxb1b; Hfh-e5.1; mesoderm/mesenchyme forkhead 3; Mf3; MGC130499; transcription factor FKH-5; Twh

RGD Orthologs

Human

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	FOXB1 (forkhead box B1)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Foxb1 (forkhead box B1)	HGNC	Treefam, NCBI, OrthoDB
Chinchilla lanigera (long-tailed chinchilla):	Foxb1 (forkhead box B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	FOXB1 (forkhead box B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	FOXB1 (forkhead box B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Foxb1 (forkhead box B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	FOXB1 (forkhead box B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	FOXB1 (forkhead box B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Foxb1 (forkhead box B1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	FOXB2 (forkhead box B2)	HGNC	OrthoDB
Alliance orthologs ³
Homo sapiens (human):	FOXB1 (forkhead box B1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	foxb1b (forkhead box B1b)	Alliance	DIOPT (Ensembl Compara\|OrthoInspector\|PANTHER\|PhylomeDB\|ZFIN)
Danio rerio (zebrafish):	foxb1a (forkhead box B1a)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	fd96Ca	Alliance	DIOPT (Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	fd96Cb	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OrthoFinder\|OrthoInspector\|PhylomeDB)
Caenorhabditis elegans (roundworm):	lin-31	Alliance	DIOPT (Hieranoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	69,664,992 - 69,668,222 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	9	69,664,992 - 69,668,222 (-)	Ensembl
GRCm38	9	69,757,710 - 69,760,940 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	69,757,710 - 69,760,940 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	69,605,517 - 69,608,747 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	69,556,916 - 69,559,991 (-)	NCBI			mm8
Celera	9	66,973,932 - 66,977,157 (-)	NCBI		Celera
Cytogenetic Map	9	D	NCBI
cM Map	9	38.76	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

colorectal cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

4,4'-sulfonyldiphenol (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-chloroethyl) sulfide (EXP)

bisphenol A (EXP,ISO)

C60 fullerene (ISO)

choline (EXP)

flusilazole (EXP)

folic acid (EXP)

fonofos (ISO)

genistein (ISO)

hexaconazole (EXP)

L-methionine (EXP)

nickel atom (ISO)

paracetamol (EXP)

parathion (ISO)

sodium arsenite (ISO)

terbufos (ISO)

triadimefon (EXP)

trichostatin A (ISO)

triclosan (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

anatomical structure morphogenesis (IBA)

axon target recognition (IMP)

cell differentiation (IBA)

cell migration in diencephalon (IMP)

epithelial cell differentiation involved in mammary gland alveolus development (IMP)

floor plate development (IMP)

hypothalamus cell migration (IMP)

inferior colliculus development (IMP)

lactation (IMP)

mammary gland lobule development (IMP)

mammillary body development (IEP,IMP)

mammillothalamic axonal tract development (IMP)

midbrain development (IMP)

negative regulation of neuron apoptotic process (IMP)

regulation of transcription by RNA polymerase II (IBA)

regulation of transcription, DNA-templated (IEA)

somitogenesis (IMP)

spinal cord development (IEP)

telencephalon cell migration (IMP)

thalamus development (IEP)

urogenital system development (IEP)

visual learning (IMP)

Cellular Component

nucleus (IDA)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

protein binding (ISO)

RNA polymerase II cis-regulatory region sequence-specific DNA binding (IBA)

sequence-specific DNA binding (IDA)

sequence-specific double-stranded DNA binding (ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal brain morphology (IAGP)

abnormal cerebellum anterior vermis morphology (IAGP)

abnormal cerebellum morphology (IAGP)

abnormal gait (IAGP)

abnormal hypothalamus morphology (IAGP)

abnormal locomotor behavior (IAGP)

abnormal mammary gland alveolus morphology (IAGP)

abnormal mammary gland epithelium morphology (IAGP)

abnormal mammary gland lobule morphology (IAGP)

abnormal mammary gland morphology (IAGP)

abnormal mammillary body morphology (IAGP)

abnormal maternal nurturing (IAGP)

abnormal midbrain morphology (IAGP)

abnormal nursing (IAGP)

abnormal sexual interaction (IAGP)

abnormal spatial learning (IAGP)

abnormal spatial working memory (IAGP)

caudal body truncation (IAGP)

decreased body size (IAGP)

decreased body weight (IAGP)

decreased embryo size (IAGP)

decreased grip strength (IAGP)

decreased inferior colliculus size (IAGP)

decreased locomotor activity (IAGP)

decreased survivor rate (IAGP)

galactostasis (IAGP)

lethality throughout fetal growth and development, incomplete penetrance (IAGP)

limb grasping (IAGP)

maternal effect (IAGP)

neonatal lethality, incomplete penetrance (IAGP)

open neural tube (IAGP)

postnatal growth retardation (IAGP)

postnatal lethality, incomplete penetrance (IAGP)

preweaning lethality, incomplete penetrance (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse brain organization revealed through direct genome-scale TF expression analysis.	Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	MGD IEA	MGD IEA
4.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7689224	PMID:8306889	PMID:8325367	PMID:8375339	PMID:8661058	PMID:8861101	PMID:9118797	PMID:9136764	PMID:9409663	PMID:9441664	PMID:9767163	PMID:9878737
PMID:10662642	PMID:11170346	PMID:11298452	PMID:11486040	PMID:12477932	PMID:12663500	PMID:14594209	PMID:14681479	PMID:15654859	PMID:16291793	PMID:16376864	PMID:16547111
PMID:17151600	PMID:18064677	PMID:18206388	PMID:18287559	PMID:18662545	PMID:18697938	PMID:18973680	PMID:19046377	PMID:19244520	PMID:19474326	PMID:19640321	PMID:20059953
PMID:20211142	PMID:20436479	PMID:20932939	PMID:21122108	PMID:21267068	PMID:21625468	PMID:21873635	PMID:22371696	PMID:22639370	PMID:24146773	PMID:24576653	PMID:24952961
PMID:25002511	PMID:25804738	PMID:28560839	PMID:29214672	PMID:30063881	PMID:30642949	PMID:32868762	PMID:33567285	PMID:34095148

Genomics

Comparative Map Data

Foxb1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	69,664,992 - 69,668,222 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	9	69,664,992 - 69,668,222 (-)	Ensembl
GRCm38	9	69,757,710 - 69,760,940 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	69,757,710 - 69,760,940 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	69,605,517 - 69,608,747 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	9	69,556,916 - 69,559,991 (-)	NCBI			mm8
Celera	9	66,973,932 - 66,977,157 (-)	NCBI		Celera
Cytogenetic Map	9	D	NCBI
cM Map	9	38.76	NCBI

FOXB1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	60,004,311 - 60,007,444 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	15	60,004,234 - 60,061,730 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	60,296,510 - 60,299,643 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	58,083,713 - 58,085,434 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	15	58,084,426 - 58,085,434	NCBI
Celera	15	37,184,381 - 37,186,102 (+)	NCBI
Cytogenetic Map	15	q22.2	NCBI
HuRef	15	37,118,460 - 37,120,181 (+)	NCBI		HuRef
CHM1_1	15	60,414,763 - 60,416,484 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	57,805,997 - 57,809,133 (+)	NCBI

Foxb1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	8	70,407,221 - 70,409,841 (-)	NCBI	mRatBN7.2
mRatBN7.2 Ensembl	8	70,408,186 - 70,409,781 (-)	Ensembl
Rnor_6.0	8	75,992,751 - 75,995,371 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	75,992,755 - 75,995,371 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	80,317,629 - 80,320,249 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	74,200,271 - 74,202,891 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	8	74,219,330 - 74,221,945 (-)	NCBI
Celera	8	71,314,793 - 71,317,413 (+)	NCBI		Celera
Cytogenetic Map	8	q24	NCBI

Foxb1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955450	14,867,941 - 14,902,990 (-)	NCBI	ChiLan1.0	ChiLan1.0

FOXB1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	15	57,283,337 - 57,286,487 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	57,284,077 - 57,285,054 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	15	38,979,727 - 38,983,040 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

FOXB1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	24,822,137 - 24,825,833 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	24,823,815 - 24,824,792 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	24,797,514 - 24,798,713 (+)	NCBI
ROS_Cfam_1.0	30	24,992,213 - 24,994,850 (+)	NCBI
ROS_Cfam_1.0 Ensembl	30	24,992,421 - 24,993,398 (+)	Ensembl
UMICH_Zoey_3.1	30	24,917,815 - 24,920,448 (+)	NCBI
UNSW_CanFamBas_1.0	30	25,000,424 - 25,003,058 (+)	NCBI
UU_Cfam_GSD_1.0	30	25,187,647 - 25,190,278 (+)	NCBI

Foxb1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	103,085,950 - 103,088,987 (+)	NCBI
SpeTri2.0	NW_004936471	20,934,524 - 20,935,584 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

FOXB1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	111,997,640 - 112,000,550 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	111,997,638 - 112,000,550 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	123,861,407 - 123,864,342 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

FOXB1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	23,502,048 - 23,505,390 (-)	NCBI	ChlSab1.1		chlSab2
ChlSab1.1 Ensembl	26	23,503,545 - 23,504,522 (-)	Ensembl	ChlSab1.1		chlSab2
Vero_WHO_p1.0	NW_023666048	117,818,793 - 117,822,194 (+)	NCBI	Vero_WHO_p1.0

Foxb1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624781	12,183,444 - 12,185,185 (-)	Ensembl	HetGla_female_1.0		hetGla2
HetGla 1.0	NW_004624781	12,182,728 - 12,185,228 (-)	NCBI	HetGla_female_1.0		hetGla2

Position Markers

X92592

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	69,758,757 - 69,758,961	UniSTS	GRCm38
MGSCv37	9	69,606,564 - 69,606,768	UniSTS	GRCm37
Celera	9	66,974,979 - 66,975,178	UniSTS
Cytogenetic Map	9	D	UniSTS
cM Map	9	41.0	UniSTS
Whitehead_YAC	9		UniSTS

AU047864

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	69,762,322 - 69,762,534	UniSTS	GRCm38
MGSCv37	9	69,610,129 - 69,610,341	UniSTS	GRCm37
Celera	9	66,978,535 - 66,978,739	UniSTS
Cytogenetic Map	9	D	UniSTS
cM Map	9	41.0	UniSTS

Foxb1

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	69,758,143 - 69,759,253	UniSTS	GRCm38
MGSCv37	9	69,605,950 - 69,607,060	UniSTS	GRCm37
Celera	9	66,974,365 - 66,975,470	UniSTS
Cytogenetic Map	9	D	UniSTS
cM Map	9	41.0	UniSTS

UniSTS:489236

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	9	69,759,020 - 69,760,652	UniSTS	GRCm38
MGSCv37	9	69,606,827 - 69,608,459	UniSTS	GRCm37
Celera	9	66,975,237 - 66,976,869	UniSTS
Cytogenetic Map	9	D	UniSTS
cM Map	9	41.0	UniSTS

Foxb1

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
Cytogenetic Map	9	D	UniSTS

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1558872	Ibdq1_m	inflammatory bowel disease QTL 1 (mouse)			Not determined		9	33978840	73439255	Mouse
4142042	Alpq3_m	alcohol preference QTL 3 (mouse)			Not determined		9	37306197	98701707	Mouse
10043971	Obq32_m	obesity QTL 32 (mouse)			Not determined		9	37819528	71819528	Mouse
12790986	Pcho9_m	plasma cholesterol 9 (mouse)					9	38099575	72099575	Mouse
12790992	Arlsq1_m	aortic root lesion size QTL 1 (mouse)					9	38099575	72099575	Mouse
12791002	Arlsq2_m	aortic root lesion size QTL 2 (mouse)					9	38099575	72099575	Mouse
12738449	Spcq2_m	sperm count QTL 2 (mouse)					9	39399885	73399885	Mouse
4141071	Ath29_m	atherosclerosis 29 (mouse)			Not determined		9	40419594	74607925	Mouse
1301702	Brm1_m	brachyury modifier 1 (mouse)			Not determined		9	40805047	74805204	Mouse
1301558	Stheal8_m	soft tissue heal 8 (mouse)			Not determined		9	43480714	77480860	Mouse
10045639	Heal28_m	wound healing/regeneration 28 (mouse)			Not determined		9	43480714	77480860	Mouse
1301435	Trigq1_m	triglyceride QTL 1 (mouse)			Not determined		9	44428174	78428262	Mouse
1300563	Pgia5_m	proteoglycan induced arthritis 5 (mouse)			Not determined		9	48831056	82831177	Mouse
1300716	Cd4ts4_m	CD4 T cell subset 4 (mouse)			Not determined		9	48831056	82831177	Mouse
4141224	Dxmod_m	doxorubicin nephropathy modifier (mouse)			Not determined			49452421	101406120	Mouse
14746993	Manh66_m	mandible shape 66 (mouse)					9	49814048	83814048	Mouse
1301184	Bdln4_m	body length 4 (mouse)			Not determined		9	50151320	84151448	Mouse
1301241	Renf1_m	renal failure 1 (mouse)			Not determined		9	52034478	99792481	Mouse
12790990	Tgl7_m	triglyceride 7 (mouse)					9	54559960	88559960	Mouse
10043877	Adip21_m	adiposity 21 (mouse)			Not determined		9	56439108	90439255	Mouse
1301549	Bbaa9_m	B.burgdorferi-associated arthritis 9 (mouse)			Not determined		9	57805047	71481754	Mouse
4141676	Neogq1_m	neonatal growth QTL 1 (mouse)			Not determined		9	57805047	86121973	Mouse
1301803	Stheal9_m	soft tissue heal 9 (mouse)			Not determined		9	59024387	93024534	Mouse
1301172	Fembrs6_m	femur breaking strength 6 (mouse)			Not determined		9	59024387	93024534	Mouse
1301456	Adip5_m	adiposity 5 (mouse)			Not determined		9	59369946	93370128	Mouse
1300848	Skull13_m	skull morphology 13 (mouse)			Not determined		9	59369946	93370128	Mouse
5491195	Mobq8_m	multigenic obesity QTL 8 (mouse)			Not determined		9	59369946	93370128	Mouse
13207569	Tcq13_m	total cholesterol QTL 13 (mouse)					9	59897283	109089068	Mouse
1301611	Lrnx3_m	learning contextual 3 (mouse)			Not determined		9	62149767	96149881	Mouse
4141833	W10q13_m	weight 10 weeks QTL 13 (mouse)			Not determined			63239711	120191934	Mouse
4141545	Tailaq2_m	tail length adjusted QTL 2 (mouse)			Not determined			63239711	120191934	Mouse
1357635	Splq4_m	spleen weight QTL 4 (mouse)			Not determined		9	63239711	120191934	Mouse
11081165	Psl6_m	promotion susceptibility QTL 6 (mouse)					9	65041191	95522808	Mouse
1301290	Smgd1_m	submucosal gland distribution 1 (mouse)			Not determined		9	65831056	86577967	Mouse
1301636	Lith5_m	lithogenic gene 5 (mouse)			Not determined		9	66089077	100089175	Mouse
10045638	Heal29_m	wound healing/regeneration 29 (mouse)			Not determined		9	67006220	101006220	Mouse
1357610	Vtbt8_m	vertebral trabecular bone trait 8 (mouse)			Not determined		9	68779563	102779705	Mouse
1301924	Bmd10_m	bone mineral density 10 (mouse)			Not determined		9	68779563	102779705	Mouse
1301302	Pas4_m	pulmonary adenoma susceptibility 4 (mouse)			Not determined		9	69121898	103121973	Mouse
10412174	Habiir4_m	hyperoxic acute lung injury imprinted region 4 (mouse)			Not determined		9	69267747	98701707	Mouse
1301621	Hpic1_m	haloperidol-induced catalepsy 1 (mouse)			Not determined		9	69428566	103428698	Mouse
14700779	Syncq8_m	synovial calcification QTL 8 (mouse)					9	69514282	70692282	Mouse

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	423
Count of miRNA genes:	323
Interacting mature miRNAs:	345
Transcripts:	ENSMUST00000071281
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022378	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC158992	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC111908	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466522	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U04198	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U90538	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X71943	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	X92592	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSMUST00000071281 ⟹ ENSMUSP00000096197

RefSeq Status:

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	9	69,664,992 - 69,668,222 (-)	Ensembl
GRCm38.p6 Ensembl	9	69,757,710 - 69,760,940 (-)	Ensembl

RefSeq Acc Id:

NM_022378 ⟹ NP_071773

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	9	69,664,992 - 69,668,222 (-)	NCBI
GRCm38	9	69,757,710 - 69,760,940 (-)	ENTREZGENE
MGSCv37	9	69,605,517 - 69,608,747 (-)	RGD
Celera	9	66,973,932 - 66,977,157 (-)	RGD
cM Map	9		ENTREZGENE

Sequence:

show sequence

AAGAAGTGGCACATTAATGAAGCGCCGCTACAGGGGTCTTTTCTGCTCCTGTCACCGCTTAAAA
CTATCAGATGGTTCGAGGGTGGACATGGAGGCAGCCACCTAGCTCAGCGGAACCACGAACACCA
CAGCAGCGTCCTCTGGATCCCTGAGGCGGCGTCTGCCACTGTCCTCACGGGCACTCCGCAGCCG
AGTTCGGTCTCCCAGCAGGGCGCACGACCCACGAGCGCGCTGCGCAGCCCGCGGAGAGGAGCTC
TACCGGGCTGAGTCCAAGCCTAGCTGGCAGCGAGTCTCACTGCTCCCCGACGCTGCGCTCCGGT
CGCGCGCAGGGAGGGACTCGGCCACCAGCCACGCCATCCCGGATGCGGACCGGCAACTTGGAAC
AACTTTAAGATTCGACCAGTCCTCCGGGCCGCGCGGACCCTGAGCAAGTGGCCAAGCAAGAAGA
TGCCTCGGCCGGGCCGCAACACGTACAGCGACCAGAAGCCGCCCTACTCATACATCTCGCTGAC
CGCCATGGCCATCCAGAGCTCTCCGGAGAAGATGCTGCCGCTCAGCGAGATCTACAAGTTCATC
ATGGACCGCTTCCCCTACTACCGGGAGAACACGCAGCGCTGGCAGAACAGCCTGCGCCACAATC
TCTCCTTCAACGATTGCTTCATCAAGATCCCGAGGCGGCCAGACCAGCCGGGCAAGGGCAGCTT
CTGGGCGCTGCATCCCAGCTGCGGGGACATGTTCGAGAACGGGAGCTTCCTGCGGCGTCGCAAG
CGCTTCAAGGTGCTCAAGTCAGACCACCTGGCGCCCAGCAAGCCGGCGGACGCCGCGCAGTACC
TCCAGCAGCAGGCTAAGCTGCGGCTCAGCGCGCTGGCCGCCTCGGGCACGCATCTGCCGCAGAT
GCCGGCCGCTGCGTACAACCTGGGCGGTGTGGCGCAGCCTTCCGGCTTCAAGCATCCCTTTGCT
ATCGAGAACATCATCGCTAGGGAGTACAAGATGCCTGGGGGGCTGGCCTTCTCTGCCATGCAGC
CGGTTCCGGCTGCCTATCCTCTCCCTAACCAGTTAACTACCATGGGCAGCTCTCTGGGCACTGG
ATGGCCACATGTGTACGGTTCCGCGGGTATGATCGACTCAGCCACCCCCATCTCCATGACTAGT
GGCGACTACAGCGCCTATGGAGTGCCGCTGAAGCCGCTGTGCCACGCCGCGGGCCAGACGTTGC
CCGCCATCCCAGTGCCCATCAAGCCCACGCCGGCCGCAGTGCCCGCGCTGCCAGCTCTGCCCGC
ACCCATCCCCACCCTGCTCTCGAACTCGCCGCCTTCGCTCAGCCCCACCTCCTCGCAGACAGCC
ACCAGCCAAAGCAGCCCCGCCACCCCTAGCGAGACACTCACCAGCCCGGCCTCCGCCTTGCACT
CGGTGGCCGTGCACTGACCCAAGGAAGCTGGGGCTCCGTCTTGGTCCACACCACCCCTCTCAAC
ACTTCCCTGCTCCGGGTCCAGCCCTCCGCGACCTAAAACCGCCACCCCGACTTGCCCATTCTAC
CTTCTTCAGTCCTCGCTCTTAGAAGAACTTTTGGTTTTGGAACCAGAAGACAAACCACAAACTT
GCCGGAAGGCGTGTGAAAGTTGTCTTCGGTCCCTCTAGGGCACCAGAGAAAACAGGGGCTAATC
CAAGCCAAGCGGTCCCTCCTGGGACCCTGAAATGCACTCCCATCCAACAGGCAGAACACCCTGA
CTCCCTCCTGCTCGGAGAAAACAGAAACAAAACAAAACAAAACAAAACAAAACAAAACAAAACA
AAACAAAACAAAACAACAAAACTACTCGTCTTCTGAGCTTGGAGAGGCATAGCTCTGGACTCTG
CGCAATTTCAAGACCAGAGACACTGCCCGGGAGCAGAAGCCCGCCGAGGCTGCAGCCGCACTAA
GAGGGCCGGATCTTCTTAGGTCCTGAAAATCTGTGGCCACAAGACCAACTCACTGATCCTCCAA
AGGGATCGCCTCCGCCCATCAGGCCGGGATGGGCGGACCGCTACTTTCCCCGGCTGCGGCTCTG
CCTCCCGGGCTTCTAAAGATTTTTTTCCCCTTCTGGGTTTTGTTTCCGGCCAGAAGCTCCCTTA
GCTGGGAGTGAGGAGGGAGGCTGCTAAAACTCCGGAGGATGCTTGTCCTACACACAAGCAAAAC
ACAGCTAAAAGTCACCGTTATTGTTTACAAAGCGCGCGGTTTAAAAAAAAATGTAAACAGTGAA
CTTGAAAATCTGCCAGGCTAGGGGCGAGGGGGTAGAGTCCTCTTTACAATTACCTGTTGTCATG
TGAATGTTTGCTCTTCTGGCCAGCTTTGGGGGTGGGAAGGAGGTAGGGGGAGAATGGGGGAAGT
TAATTGGGATGTTAACTTTCTTACTATTTAGAGACCTTTTTAGCTATTTATTTTGATGAAAGAG
AAAAGAAAGGAAAAGGAAAAAGAAAAGAAAAAAGAAAGAAAGGAACGTAAACTAAGCCCGAGGG
AGAAATCCTAGGGCGAGTGGGGAAGTGTGTAGATGAGCCGACTGGGAAGGGGAAGGGGGTGTCA
GCAGAGATGTCCTCTGGACAGATCTTTCTGTTAAAAGAACTTTTCCGTGAAGCTAAAGGGCTGC
AAAGAGTTGTAAATAGGAATGATTTACACTGTGTAAAATGCACTTTGGTTTGGTATGTTCCTTT
TAGCATTCTAGGTAATTGACAGAAAACAAACAAACAAACAAACAAACAAAGAACAACCCAATAG
TTGTTCCATTGTGACCTGCTTAATTTAAAAAAGAAATTGTAGTGTTGTTCAAGCTGTGAAAAAA
AAATCCCTTTTATTTTTCTTCCTCTCTGCACAGAATTCGCATGGCATTTTAAATATTGATGTCC
TTGTTCTCAGCATGCCCATTTTAAGACAGAGTTTTAAAAGGTGTCTACATTAAATTATGACCTA
GTCTAAATAATATTTTCTCATTAAAATATGTAAATTCGAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_071773	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB57686	(Get FASTA)	NCBI Sequence Viewer
	AAD12223	(Get FASTA)	NCBI Sequence Viewer
	AAI11909	(Get FASTA)	NCBI Sequence Viewer
	CAA50745	(Get FASTA)	NCBI Sequence Viewer
	CAA63336	(Get FASTA)	NCBI Sequence Viewer
	EDL26174	(Get FASTA)	NCBI Sequence Viewer
	Q64732	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_071773 ⟸ NM_022378

- UniProtKB:

Q64732 (UniProtKB/Swiss-Prot)

- Sequence:

show sequence

MPRPGRNTYSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHN
LSFNDCFIKIPRRPDQPGKGSFWALHPSCGDMFENGSFLRRRKRFKVLKSDHLAPSKPADAAQY
LQQQAKLRLSALAASGTHLPQMPAAAYNLGGVAQPSGFKHPFAIENIIAREYKMPGGLAFSAMQ
PVPAAYPLPNQLTTMGSSLGTGWPHVYGSAGMIDSATPISMTSGDYSAYGVPLKPLCHAAGQTL
PAIPVPIKPTPAAVPALPALPAPIPTLLSNSPPSLSPTSSQTATSQSSPATPSETLTSPASALH
SVAVH

hide sequence

RefSeq Acc Id:

ENSMUSP00000096197 ⟸ ENSMUST00000071281

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q64732-F1-model_v2	AlphaFold	Q64732	1-325	view protein structure

Promoters

RGD ID:

8670074

Promoter ID:

EPDNEW_M13068

Type:

multiple initiation site

Name:

Foxb1_1

Description:

Mus musculus forkhead box B1 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	9	69,760,874 - 69,760,934	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1927549	AgrOrtholog
Ensembl Genes	ENSMUSG00000059246	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSMUSP00000096197	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000071281	ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH	1.10.10.10	UniProtKB/Swiss-Prot
InterPro	Fork_head_dom	UniProtKB/Swiss-Prot
	TF_fork_head_CS_1	UniProtKB/Swiss-Prot
	TF_fork_head_CS_2	UniProtKB/Swiss-Prot
	WH-like_DNA-bd_sf	UniProtKB/Swiss-Prot
	WH_DNA-bd_sf	UniProtKB/Swiss-Prot
KEGG Report	mmu:64290	UniProtKB/Swiss-Prot
MGD	MGI:1927549	ENTREZGENE
NCBI Gene	64290	ENTREZGENE
Pfam	Forkhead	UniProtKB/Swiss-Prot
PhenoGen	Foxb1	PhenoGen
PRINTS	FORKHEAD	UniProtKB/Swiss-Prot
PROSITE	FORK_HEAD_1	UniProtKB/Swiss-Prot
	FORK_HEAD_2	UniProtKB/Swiss-Prot
	FORK_HEAD_3	UniProtKB/Swiss-Prot
SMART	SM00339	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF46785	UniProtKB/Swiss-Prot
UniProt	FOXB1_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary	O08753	UniProtKB/Swiss-Prot
	Q2M2M4	UniProtKB/Swiss-Prot

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar