Rbm11 (RNA binding motif protein 11) - Rat Genome Database

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Gene: Rbm11 (RNA binding motif protein 11) Mus musculus
Analyze
Symbol: Rbm11
Name: RNA binding motif protein 11
RGD ID: 1313080
MGI Page MGI
Description: Enables poly(U) RNA binding activity. Predicted to be involved in regulation of alternative mRNA splicing, via spliceosome. Predicted to act upstream of or within cellular response to oxidative stress. Predicted to be located in nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; sensory organ; and skeleton. Orthologous to human RBM11 (RNA binding motif protein 11).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: A330018F01; putative RNA-binding protein 11; RNA-binding motif protein 11; splicing regulator RBM11
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391675,389,796 - 75,399,706 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1675,389,732 - 75,399,717 (+)EnsemblGRCm39 Ensembl
GRCm381675,592,844 - 75,602,825 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1675,592,844 - 75,602,829 (+)EnsemblGRCm38mm10GRCm38
MGSCv371675,593,136 - 75,603,070 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361675,475,524 - 75,484,382 (+)NCBIMGSCv36mm8
Celera1675,829,936 - 75,839,869 (+)NCBICelera
Cytogenetic Map16C3.1NCBI
cM Map1643.22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
nuclear speck  (ISO)
nucleoplasm  (ISO)
nucleus  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. A gene expression map of human chromosome 21 orthologues in the mouse. Gitton Y, etal., Nature 2002 Dec 5;420(6915):586-90.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Human chromosome 21 gene expression atlas in the mouse. Reymond A, etal., Nature 2002 Dec 5;420(6915):582-6.
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14681479   PMID:16033648   PMID:16141072   PMID:16141073   PMID:21677750  
PMID:21873635   PMID:21984414  


Genomics

Comparative Map Data
Rbm11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391675,389,796 - 75,399,706 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1675,389,732 - 75,399,717 (+)EnsemblGRCm39 Ensembl
GRCm381675,592,844 - 75,602,825 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1675,592,844 - 75,602,829 (+)EnsemblGRCm38mm10GRCm38
MGSCv371675,593,136 - 75,603,070 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361675,475,524 - 75,484,382 (+)NCBIMGSCv36mm8
Celera1675,829,936 - 75,839,869 (+)NCBICelera
Cytogenetic Map16C3.1NCBI
cM Map1643.22NCBI
RBM11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382114,216,157 - 14,228,372 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2114,216,130 - 14,228,372 (+)EnsemblGRCh38hg38GRCh38
GRCh372115,588,478 - 15,600,693 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362114,510,350 - 14,522,552 (+)NCBINCBI36Build 36hg18NCBI36
Build 342114,510,349 - 14,522,552NCBI
Celera21745,717 - 757,944 (+)NCBICelera
Cytogenetic Map21q11.2NCBI
HuRef21958,833 - 971,058 (+)NCBIHuRef
CHM1_12115,148,999 - 15,161,227 (+)NCBICHM1_1
T2T-CHM13v2.02112,558,865 - 12,571,078 (+)NCBIT2T-CHM13v2.0
Rbm11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81127,721,870 - 27,731,125 (+)NCBIGRCr8
mRatBN7.21114,234,851 - 14,244,092 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1114,234,890 - 14,244,090 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1122,859,949 - 22,869,159 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01115,586,333 - 15,595,543 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01114,754,201 - 14,763,411 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01114,005,704 - 14,015,723 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1114,005,732 - 14,014,962 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01117,664,383 - 17,674,391 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41114,381,923 - 14,391,904 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11114,379,374 - 14,390,086 (+)NCBI
Celera1114,248,500 - 14,258,481 (+)NCBICelera
Cytogenetic Map11p11NCBI
Rbm11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540716,071,208 - 16,081,949 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540716,071,186 - 16,082,332 (+)NCBIChiLan1.0ChiLan1.0
RBM11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22210,693,134 - 10,705,375 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1215,526,875 - 5,538,726 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v021942,533 - 954,775 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12114,309,922 - 14,322,142 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2114,309,883 - 14,322,142 (+)Ensemblpanpan1.1panPan2
RBM11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13111,204,273 - 11,217,526 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3111,203,207 - 11,217,509 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3111,215,073 - 11,228,492 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03111,228,501 - 11,241,994 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3111,228,404 - 11,241,994 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13111,201,584 - 11,215,096 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03111,239,110 - 11,252,365 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03111,635,470 - 11,648,982 (+)NCBIUU_Cfam_GSD_1.0
Rbm11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497112,327,134 - 12,337,002 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365057,246,844 - 7,256,790 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365057,246,854 - 7,256,763 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBM11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13179,180,467 - 179,191,924 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113179,180,611 - 179,191,934 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213189,369,722 - 189,381,248 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RBM11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1278,390,304 - 78,395,739 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605075,603,734 - 75,618,143 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rbm11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247452,685,372 - 2,697,518 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247452,685,445 - 2,696,791 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rbm11
467 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1080
Count of miRNA genes:348
Interacting mature miRNAs:390
Transcripts:ENSMUST00000046378, ENSMUST00000114249, ENSMUST00000114253
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
1302096Aod1a_mautoimmune ovarian dysgenesis 1a (mouse)Not determined163544664392573008Mouse
26884416Bzwq5_mbi-zygomatic width QTL 5, 5 week (mouse)163732036284696888Mouse
11522747Eae41_mexperimental allergic encephalomyelitis susceptibility 41 (mouse)164039913478015472Mouse
1357778Diobq_mdiet-induced obesity QTL (mouse)Not determined164219781782331174Mouse
4141212Imraq3_mimmune response to AAV2 QTL 3 (mouse)Not determined164438335078383506Mouse
1301719Remslp3_mrapid eye movement sleep 3 (mouse)Not determined164438335078383506Mouse
14928310Manh80_mmandible shape 80 (mouse)164821984182219841Mouse
1301394Eae11_msusceptibility to experimental allergic encephalomyelitis 11 (mouse)Not determined165356189187562035Mouse
1301364Lith14_mlithogenic gene 14 (mouse)Not determined165566184689661961Mouse
1301125Sluc27_msusceptibility to lung cancer 27 (mouse)Not determined166160864495608764Mouse
4141113Tgq28_mtriglyceride QTL 28 (mouse)Not determined6298664696986646Mouse
1300928Etia_methanol induced activation (mouse)Not determined166331390797314016Mouse
1558740Bpq9_mblood pressure QTL 9 (mouse)Not determined166332733697327472Mouse
1302194Pgia10_mproteoglycan induced arthritis 10 (mouse)Not determined166860072298008968Mouse
1301032Tauph_mtau phosphorylation (mouse)Not determined166907613298008968Mouse
11049573Lmr18b_mleishmaniasis resistance 18b (mouse)166912761198008968Mouse
11049574Lmr18a_mleishmaniasis resistance 18a (mouse)166912761198008968Mouse
4142262Lmr18_mleishmaniasis resistance 18 (mouse)Not determined166912761198008968Mouse
11522753Cocia19_mcocaine-induced activity, QTL 19 (mouse)166925448298008968Mouse
1301598Renf2_mrenal failure 2 (mouse)Not determined167038025298008968Mouse
10412076Pod_mplasticity of ocular dominance (mouse)Not determined167354484584350326Mouse
12880403Sefq1_mstress effect QTL 1 (mouse)167469664378896643Mouse

Markers in Region
Rbm11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C3.1UniSTS
cM MapUN UniSTS
Rbm11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C3.1UniSTS
cM Map16 UniSTS
Rbm11  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16C3.1UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000046378   ⟹   ENSMUSP00000038956
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1675,389,732 - 75,398,583 (+)Ensembl
GRCm38.p6 Ensembl1675,592,844 - 75,601,695 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114249   ⟹   ENSMUSP00000109887
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1675,389,732 - 75,399,717 (+)Ensembl
GRCm38.p6 Ensembl1675,592,844 - 75,602,829 (+)Ensembl
RefSeq Acc Id: ENSMUST00000114253   ⟹   ENSMUSP00000109891
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1675,389,779 - 75,399,713 (+)Ensembl
GRCm38.p6 Ensembl1675,592,891 - 75,602,825 (+)Ensembl
RefSeq Acc Id: NM_001417063   ⟹   NP_001403992
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391675,389,796 - 75,399,706 (+)NCBI
RefSeq Acc Id: NM_001417067   ⟹   NP_001403996
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391675,389,796 - 75,399,706 (+)NCBI
RefSeq Acc Id: NM_001417069   ⟹   NP_001403998
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391675,389,796 - 75,399,706 (+)NCBI
RefSeq Acc Id: NM_198302   ⟹   NP_938044
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391675,389,796 - 75,399,706 (+)NCBI
GRCm381675,592,891 - 75,602,825 (+)NCBI
MGSCv371675,593,136 - 75,603,070 (+)RGD
Celera1675,829,936 - 75,839,869 (+)RGD
cM Map16 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_938044   ⟸   NM_198302
- Peptide Label: isoform 1
- UniProtKB: D3Z0X9 (UniProtKB/Swiss-Prot),   Q8BYK1 (UniProtKB/Swiss-Prot),   Q80YT9 (UniProtKB/Swiss-Prot),   H9KUZ7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000038956   ⟸   ENSMUST00000046378
RefSeq Acc Id: ENSMUSP00000109887   ⟸   ENSMUST00000114249
RefSeq Acc Id: ENSMUSP00000109891   ⟸   ENSMUST00000114253
RefSeq Acc Id: NP_001403998   ⟸   NM_001417069
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001403996   ⟸   NM_001417067
- Peptide Label: isoform 3
RefSeq Acc Id: NP_001403992   ⟸   NM_001417063
- Peptide Label: isoform 2
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q80YT9-F1-model_v2 AlphaFold Q80YT9 1-238 view protein structure

Promoters
RGD ID:13674240
Promoter ID:EPDNEW_M21269
Type:initiation region
Name:Rbm11_1
Description:Mus musculus RNA binding motif protein 11 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381675,592,908 - 75,592,968EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2447622 AgrOrtholog
Ensembl Genes ENSMUSG00000032940 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000046378.14 UniProtKB/Swiss-Prot
  ENSMUST00000114249.8 UniProtKB/TrEMBL
  ENSMUST00000114253 ENTREZGENE
  ENSMUST00000114253.2 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.330 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RBM11_RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RRM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:224344 UniProtKB/Swiss-Prot
MGD MGI:2447622 ENTREZGENE
NCBI Gene 224344 ENTREZGENE
PANTHER RNA BINDING MOTIF RBM PROTEIN -RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SPLICING REGULATOR RBM11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rbm11 PhenoGen
PROSITE RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART RRM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt D3Z0X9 ENTREZGENE
  H9KUZ7 ENTREZGENE, UniProtKB/TrEMBL
  Q80YT9 ENTREZGENE
  Q8BYK1 ENTREZGENE
  RBM11_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary D3Z0X9 UniProtKB/Swiss-Prot
  Q8BYK1 UniProtKB/Swiss-Prot