Gask1a (golgi associated kinase 1A) - Rat Genome Database
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Gene: Gask1a (golgi associated kinase 1A) Mus musculus
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Symbol: Gask1a
Name: golgi associated kinase 1A
RGD ID: 1313021
MGI Page MGI
Description: Localizes to Golgi apparatus; endoplasmic reticulum; and extracellular region. Is expressed in naris; orbito-sphenoid; otic capsule; temporal bone petrous part; and turbinate bone primordium. Orthologous to human GASK1A (golgi associated kinase 1A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; carbon nanotube.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: C730027P07Rik; Fam19; Fam198a; family with sequence similarity 198, member A; Golgi-associated kinase 1A; hypothetical protein LOC245050; MGC130602
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,780,054 - 121,817,379 (+)NCBIGRCm39mm39
GRCm389121,950,988 - 121,988,313 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,950,988 - 121,980,209 (+)EnsemblGRCm38mm10GRCm38
MGSCv379121,861,852 - 121,887,803 (+)NCBIGRCm37mm9NCBIm37
MGSCv369121,801,432 - 121,827,385 (+)NCBImm8
Celera9122,428,461 - 122,453,585 (+)NCBICelera
Cytogenetic Map9F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:16141072   PMID:16141073   PMID:21267068   PMID:30188967  


Genomics

Comparative Map Data
Gask1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399121,780,054 - 121,817,379 (+)NCBIGRCm39mm39
GRCm389121,950,988 - 121,988,313 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9121,950,988 - 121,980,209 (+)EnsemblGRCm38mm10GRCm38
MGSCv379121,861,852 - 121,887,803 (+)NCBIGRCm37mm9NCBIm37
MGSCv369121,801,432 - 121,827,385 (+)NCBImm8
Celera9122,428,461 - 122,453,585 (+)NCBICelera
Cytogenetic Map9F4NCBI
GASK1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl342,979,267 - 43,060,211 (+)EnsemblGRCh38hg38GRCh38
GRCh38342,979,311 - 43,057,715 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37343,020,759 - 43,099,207 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36342,995,763 - 43,074,211 (+)NCBINCBI36hg18NCBI36
Celera342,958,596 - 43,036,717 (+)NCBI
Cytogenetic Map3p22.1NCBI
HuRef343,063,911 - 43,142,036 (+)NCBIHuRef
CHM1_1342,970,704 - 43,048,832 (+)NCBICHM1_1
Gask1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.08130,581,072 - 130,614,118 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8130,581,062 - 130,612,510 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08129,756,079 - 129,789,361 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48126,953,763 - 126,991,033 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.18126,977,122 - 127,007,592 (-)NCBI
Celera8120,735,518 - 120,768,086 (+)NCBICelera
Cytogenetic Map8q32NCBI
Gask1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542027,901,885 - 27,952,998 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542027,900,342 - 27,931,079 (-)NCBIChiLan1.0ChiLan1.0
GASK1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1343,945,071 - 44,029,286 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl343,945,071 - 44,022,902 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0342,845,169 - 42,967,507 (+)NCBIMhudiblu_PPA_v0panPan3
GASK1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2312,034,221 - 12,085,293 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12312,019,079 - 12,085,993 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Gask1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366952,150,547 - 2,206,931 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GASK1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1326,415,710 - 26,473,645 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11326,415,637 - 26,473,649 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21329,168,962 - 29,181,652 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GASK1A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1224,425,802 - 4,506,027 (+)NCBI
ChlSab1.1 Ensembl224,426,912 - 4,506,776 (+)Ensembl
Gask1a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473076,833,237 - 76,875,323 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10412242Alpq8_malcohol preference QTL 8 (mouse)Not determined989284925123284925Mouse
1301649Psl1_mpromotion susceptibility QTL 1 (mouse)Not determined989412277123412396Mouse
18182932Metl3_mmetabolite locus 3, N-acetylglutamate (mouse)989563342123563342Mouse
12910770Splic1_mspleen iron content 1 (mouse)991413879124595110Mouse
12910772Lvic6_mliver iron content 6 (mouse)991413879124595110Mouse
12910773Splic3_mspleen iron content 3 (mouse)991413879124595110Mouse
1558767Skmw11_mskeletal muscle weight 11 (mouse)Not determined991641084124595110Mouse
13463474Hbbcq5_mhemoglobin concentration QTL 5 (mouse)991641084124595110Mouse
13463475Hctq7_mhematocrit QTL 7 (mouse)991641084124595110Mouse
13463477Rbc9_mred blood cell count 9 (mouse)991641084124595110Mouse
13463478Mchq18_mmean corpuscular hemoglobin QTL 18 (mouse)991641084124595110Mouse
13463480Mchcq2_mmean corpuscular hemoglobin concentration QTL 2 (mouse)991641084124595110Mouse
12904937Edlmmq9_mextensor digitorum longus muscle mass QTL 9 (mouse)991683173124595110Mouse
12904947Tammq7_mtibialis anterior muscle mass QTL 7 (mouse)991683173124595110Mouse
12904961Gmmq7_mgastrocnemius muscle mass QTL 7 (mouse)991683173124595110Mouse
1302001Bdln5_mbody length 5 (mouse)Not determined993762590124595110Mouse
1301484Bwq6_mbody weight (mouse)Not determined993762590124595110Mouse
14746992Manh67_mmandible shape 67 (mouse)994036768124595110Mouse
11537364Cnes5_mC. neoformans susceptibility locus 5 (mouse)996917590124595110Mouse
1301297Lcho1_mliver cholesterol 1 (mouse)Not determined9101060861124595110Mouse
1357627Tgq2_mtriglyceride QTL 2 (mouse)Not determined9102000187124595110Mouse
1357648Obq18_mobesity QTL 18 (mouse)Not determined9102000187124595110Mouse
1301789Pbwg4_mpostnatal body weight growth 4 (mouse)Not determined9103289445124595110Mouse
10412290Pvacm1l_mplasma vascular cell adhesion molecule 1 levels (mouse)Not determined9103289445124595110Mouse
12879896Berr3_mberghei resistance locus 3 (mouse)9103289445124595110Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:625
Count of miRNA genes:418
Interacting mature miRNAs:479
Transcripts:ENSMUST00000043011
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000043011   ⟹   ENSMUSP00000040221
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9121,950,988 - 121,980,209 (+)Ensembl
RefSeq Acc Id: ENSMUST00000213773   ⟹   ENSMUSP00000151175
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9121,952,734 - 121,978,687 (+)Ensembl
RefSeq Acc Id: ENSMUST00000214536   ⟹   ENSMUSP00000150724
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9121,951,020 - 121,980,206 (+)Ensembl
RefSeq Acc Id: ENSMUST00000215990   ⟹   ENSMUSP00000149755
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl9121,951,035 - 121,978,681 (+)Ensembl
RefSeq Acc Id: NM_001199927   ⟹   NP_001186856
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399121,780,086 - 121,809,274 (+)NCBI
GRCm389121,951,020 - 121,980,208 (+)NCBI
Celera9122,426,715 - 122,455,108 (+)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_177743   ⟹   NP_808411
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399121,780,054 - 121,809,274 (+)NCBI
GRCm389121,950,988 - 121,980,208 (+)NCBI
MGSCv379121,861,852 - 121,887,803 (+)RGD
Celera9122,426,715 - 122,455,108 (+)ENTREZGENE
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006512130   ⟹   XP_006512193
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399121,780,057 - 121,809,518 (+)NCBI
GRCm389121,950,991 - 121,980,452 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512131   ⟹   XP_006512194
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399121,780,057 - 121,809,518 (+)NCBI
GRCm389121,950,991 - 121,980,452 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006512132   ⟹   XP_006512195
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm399121,780,057 - 121,817,379 (+)NCBI
GRCm389121,950,991 - 121,988,313 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_808411   ⟸   NM_177743
- Peptide Label: isoform 1 precursor
- UniProtKB: Q3UY90 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001186856   ⟸   NM_001199927
- Peptide Label: isoform 2 precursor
- UniProtKB: Q3UY90 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006512195   ⟸   XM_006512132
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006512194   ⟸   XM_006512131
- Peptide Label: isoform X3
- UniProtKB: Q3UY90 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006512193   ⟸   XM_006512130
- Peptide Label: isoform X2
- UniProtKB: Q3UY90 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000151175   ⟸   ENSMUST00000213773
RefSeq Acc Id: ENSMUSP00000149755   ⟸   ENSMUST00000215990
RefSeq Acc Id: ENSMUSP00000150724   ⟸   ENSMUST00000214536
RefSeq Acc Id: ENSMUSP00000040221   ⟸   ENSMUST00000043011

Promoters
RGD ID:6844282
Promoter ID:MM_KWN:59222
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver,   Lung
Transcripts:ENSMUST00000043011,   UC009SEI.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv369121,860,001 - 121,860,501 (+)MPROMDB
RGD ID:8671288
Promoter ID:EPDNEW_M13674
Type:initiation region
Name:Fam198a_1
Description:Mus musculus family with sequence similarity 198, member A ,transcript variant 1, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm389121,951,057 - 121,951,117EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3041196 AgrOrtholog
Ensembl Genes ENSMUSG00000038233 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000040221 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000149755 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000150724 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000151175 UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000043011 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000213773 UniProtKB/Swiss-Prot
  ENSMUST00000214536 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000215990 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro FAM198 UniProtKB/Swiss-Prot
KEGG Report mmu:245050 UniProtKB/Swiss-Prot
MGD MGI:3041196 ENTREZGENE
NCBI Gene 245050 ENTREZGENE
PANTHER PTHR15905 UniProtKB/Swiss-Prot
Pfam FAM198 UniProtKB/Swiss-Prot
PhenoGen Gask1a PhenoGen
UniGene Mm.71062 ENTREZGENE
UniProt GAK1A_MOUSE UniProtKB/Swiss-Prot
  Q3UUE5_MOUSE UniProtKB/TrEMBL
  Q3UY90 ENTREZGENE
UniProt Secondary Q3TYS0 UniProtKB/Swiss-Prot
  Q3UTV8 UniProtKB/Swiss-Prot
  Q8C7H6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-02-19 Gask1a  golgi associated kinase 1A  Fam198a  family with sequence similarity 198, member A  Symbol and/or name change 5135510 APPROVED