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Gene: RPS6KB2 (ribosomal protein S6 kinase B2) Homo sapiens
Symbol: RPS6KB2
Name: ribosomal protein S6 kinase B2
RGD ID: 1313003
Description: Predicted to have protein serine/threonine kinase activity. Involved in TOR signaling and positive regulation of translational initiation. Predicted to localize to cytoplasm and nucleus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 70 kDa ribosomal protein S6 kinase 2; KLS; p70 ribosomal S6 kinase beta; p70 S6 kinase beta; p70 S6K-beta; p70 S6KB; p70(S6K)-beta; P70-beta; P70-beta-1; P70-beta-2; p70-S6K 2; P70S6K2; p70S6Kb; ribosomal protein S6 kinase beta-2; ribosomal protein S6 kinase, 70kDa, polypeptide 2; S6 kinase-related kinase; S6K-beta; S6K-beta-2; S6K-beta2; S6K2; S6KB; S6Kbeta; S6KI(2); serine/threonine-protein kinase 14 beta; serine/threonine-protein kinase 14B; SRK; STK14B
Mus musculus (house mouse) : Rps6kb2 (ribosomal protein S6 kinase, polypeptide 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Rps6kb2 (ribosomal protein S6 kinase B2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rps6kb2 (ribosomal protein S6 kinase B2)
Pan paniscus (bonobo/pygmy chimpanzee) : RPS6KB2 (ribosomal protein S6 kinase B2)
Canis lupus familiaris (dog) : RPS6KB2 (ribosomal protein S6 kinase B2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rps6kb2 (ribosomal protein S6 kinase B2)
Sus scrofa (pig) : RPS6KB2 (ribosomal protein S6 kinase B2)
Chlorocebus sabaeus (African green monkey) : RPS6KB2 (ribosomal protein S6 kinase B2)
Heterocephalus glaber (naked mole-rat) : Rps6kb2 (ribosomal protein S6 kinase B2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1167,428,460 - 67,435,401 (+)EnsemblGRCh38hg38GRCh38
GRCh381167,428,475 - 67,435,408 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371167,195,935 - 67,202,879 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361166,952,511 - 66,959,455 (+)NCBINCBI36hg18NCBI36
Build 341166,952,510 - 66,959,454NCBI
Celera1164,529,049 - 64,535,993 (+)NCBI
Cytogenetic Map11q13.2NCBI
HuRef1163,523,985 - 63,530,929 (+)NCBIHuRef
CHM1_11167,079,005 - 67,085,949 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on RPS6KB2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1313003
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.