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Gene: Atp6v0a4 (ATPase, H+ transporting, lysosomal V0 subunit A4) Mus musculus
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Symbol: Atp6v0a4
Name: ATPase, H+ transporting, lysosomal V0 subunit A4
Description: Predicted to have ATPase binding activity; proton-exporting ATPase activity, phosphorylative mechanism; and proton-transporting ATPase activity, rotational mechanism. Involved in proton transmembrane transport. Localizes to several cellular components, including the apical plasma membrane; brush border; and vacuolar proton-transporting V-type ATPase complex. Used to study renal tubular acidosis. Human ortholog(s) of this gene implicated in renal tubular acidosis. Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; respiratory system; and sensory organ. Orthologous to human ATP6V0A4 (ATPase H+ transporting V0 subunit a4); PARTICIPATES IN oxidative phosphorylation pathway; rheumatoid arthritis pathway; tuberculosis pathway; INTERACTS WITH (S)-nicotine; 1,1-dichloroethene; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: a4; Atp6n1b; ATPase, H+ transporting, lysosomal (vacuolar proton pump) noncatalytic accessory protein 1B; V-ATPase 116 kDa; V-ATPase alpha 4; V-type proton ATPase 116 kDa subunit a; V-type proton ATPase 116 kDa subunit a isoform 4; vacuolar proton translocating ATPase 100 kDa a4 subunit; vacuolar proton translocating ATPase 116 kDa subunit a kidney isoform
Orthologs:
Homo sapiens (human) : ATP6V0A4 (ATPase H+ transporting V0 subunit a4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Atp6v0a4 (ATPase H+ transporting V0 subunit a4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp6v0a4 (ATPase H+ transporting V0 subunit a4)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP6V0A4 (ATPase H+ transporting V0 subunit a4)
Canis lupus familiaris (dog) : ATP6V0A4 (ATPase H+ transporting V0 subunit a4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp6v0a4 (ATPase H+ transporting V0 subunit a4)
Sus scrofa (pig) : ATP6V0A4 (ATPase H+ transporting V0 subunit a4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38638,048,483 - 38,124,586 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37637,998,483 - 38,074,586 (-)NCBIGRCm37mm9NCBIm37
MGSCv36637,978,091 - 38,054,182 (-)NCBImm8
Celera638,029,008 - 38,104,935 (-)NCBICelera
Cytogenetic Map6 B1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Atp6v0a4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312857
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.