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Gene: PKNOX1 (PBX/knotted 1 homeobox 1) Homo sapiens
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Symbol: PKNOX1
Name: PBX/knotted 1 homeobox 1
Description: Exhibits sequence-specific double-stranded DNA binding activity. Predicted to be involved in angiogenesis; hemopoiesis; and regulation of transcription by RNA polymerase II. Predicted to localize to nuclear chromatin; INTERACTS WITH aflatoxin B1; arsenous acid; beta-naphthoflavone.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: homeobox protein PKNOX1; homeobox protein PREP-1; human homeobox-containing protein; Pbx regulating protein-1; PBX/knotted homeobox 1; pkonx1c; PREP1
Orthologs:
Mus musculus (house mouse) : Pknox1 (Pbx/knotted 1 homeobox)  MGI  Alliance
Rattus norvegicus (Norway rat) : Pknox1 (PBX/knotted 1 homeobox 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pknox1 (PBX/knotted 1 homeobox 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PKNOX1 (PBX/knotted 1 homeobox 1)
Canis lupus familiaris (dog) : PKNOX1 (PBX/knotted 1 homeobox 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pknox1 (PBX/knotted 1 homeobox 1)
Sus scrofa (pig) : PKNOX1 (PBX/knotted 1 homeobox 1)
Chlorocebus sabaeus (African green monkey) : PKNOX1 (PBX/knotted 1 homeobox 1)
Heterocephalus glaber (naked mole-rat) : Pknox1 (PBX/knotted 1 homeobox 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2142,974,510 - 43,033,931 (+)EnsemblGRCh38hg38GRCh38
GRCh382142,974,510 - 43,033,931 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh372144,394,643 - 44,453,688 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362143,267,712 - 43,326,757 (+)NCBINCBI36hg18NCBI36
Build 342143,267,711 - 43,326,757NCBI
Celera2129,545,263 - 29,606,363 (+)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2129,842,641 - 29,872,199 (+)NCBIHuRef
CHM1_12143,955,547 - 44,014,948 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on PKNOX1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312771
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.