MOSPD3 (motile sperm domain containing 3) - Rat Genome Database

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Gene: MOSPD3 (motile sperm domain containing 3) Homo sapiens
Analyze
Symbol: MOSPD3
Name: motile sperm domain containing 3
RGD ID: 1312722
HGNC Page HGNC:25078
Description: Predicted to act upstream of or within heart development. Predicted to be located in membrane. Predicted to be active in cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CDS3; motile sperm domain-containing protein 3; NET30
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,612,162 - 100,615,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,612,102 - 100,615,384 (+)EnsemblGRCh38hg38GRCh38
GRCh377100,209,785 - 100,213,000 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,047,661 - 100,050,936 (+)NCBINCBI36Build 36hg18NCBI36
Build 34799,854,783 - 99,857,649NCBI
Celera794,939,506 - 94,942,781 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,841,379 - 94,844,443 (+)NCBIHuRef
CHM1_17100,140,271 - 100,143,546 (+)NCBICHM1_1
T2T-CHM13v2.07101,852,243 - 101,855,458 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,569,356 - 99,572,631 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
heart development  (IEA,ISO)

Cellular Component
cytoplasm  (IBA)
membrane  (IEA)

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. A novel transmembrane MSP-containing protein that plays a role in right ventricle development. Pall GS, etal., Genomics. 2004 Dec;84(6):1051-9.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9799793   PMID:12690205   PMID:15146197   PMID:15489334   PMID:21873635   PMID:28986522   PMID:31741433   PMID:32296183   PMID:33296653   PMID:33961781  


Genomics

Comparative Map Data
MOSPD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387100,612,162 - 100,615,377 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl7100,612,102 - 100,615,384 (+)EnsemblGRCh38hg38GRCh38
GRCh377100,209,785 - 100,213,000 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367100,047,661 - 100,050,936 (+)NCBINCBI36Build 36hg18NCBI36
Build 34799,854,783 - 99,857,649NCBI
Celera794,939,506 - 94,942,781 (+)NCBICelera
Cytogenetic Map7q22.1NCBI
HuRef794,841,379 - 94,844,443 (+)NCBIHuRef
CHM1_17100,140,271 - 100,143,546 (+)NCBICHM1_1
T2T-CHM13v2.07101,852,243 - 101,855,458 (+)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2799,569,356 - 99,572,631 (+)NCBI
Mospd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395137,594,907 - 137,599,342 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5137,594,907 - 137,599,320 (-)EnsemblGRCm39 Ensembl
GRCm385137,596,645 - 137,601,079 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5137,596,645 - 137,601,058 (-)EnsemblGRCm38mm10GRCm38
MGSCv375138,037,873 - 138,042,268 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365137,826,433 - 137,830,828 (-)NCBIMGSCv36mm8
Celera5134,580,206 - 134,584,362 (-)NCBICelera
Cytogenetic Map5G2NCBI
cM Map576.59NCBI
Mospd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81224,728,012 - 24,737,078 (+)NCBIGRCr8
mRatBN7.21219,095,203 - 19,100,303 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1219,095,242 - 19,099,477 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1220,250,808 - 20,254,862 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01220,863,689 - 20,867,743 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01219,928,019 - 19,932,073 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01222,164,978 - 22,169,251 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1222,165,486 - 22,169,241 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01224,182,325 - 24,186,564 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41219,663,139 - 19,666,904 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11219,652,700 - 19,656,466 (-)NCBI
Celera1220,901,044 - 20,904,809 (+)NCBICelera
Cytogenetic Map12q12NCBI
Mospd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955573295,695 - 298,525 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955573295,746 - 298,496 (-)NCBIChiLan1.0ChiLan1.0
MOSPD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v26118,523,458 - 118,526,765 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17166,788,108 - 166,791,396 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0792,639,151 - 92,642,464 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.17106,040,375 - 106,043,666 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl7106,040,375 - 106,047,767 (+)Ensemblpanpan1.1panPan2
MOSPD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.169,079,593 - 9,082,480 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl69,079,636 - 9,081,804 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha610,784,009 - 10,786,926 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.069,013,794 - 9,016,714 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl69,013,837 - 9,016,546 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.168,866,305 - 8,869,222 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.068,843,982 - 8,846,900 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.069,026,223 - 9,029,140 (-)NCBIUU_Cfam_GSD_1.0
Mospd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344133,372,651 - 133,374,505 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936543661,730 - 663,878 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936543661,547 - 663,879 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MOSPD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl38,531,228 - 8,533,932 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.138,531,745 - 8,533,828 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.237,926,688 - 7,928,771 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MOSPD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12812,597,154 - 12,600,670 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2812,597,128 - 12,600,796 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660703,704,092 - 3,707,603 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mospd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474016,472,273 - 16,475,034 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474016,472,363 - 16,475,216 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in MOSPD3
14 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q21.3-22.1(chr7:98288474-101259804)x3 copy number gain See cases [RCV000053573] Chr7:98288474..101259804 [GRCh38]
Chr7:97917786..100903085 [GRCh37]
Chr7:97755722..100689805 [NCBI36]
Chr7:7q21.3-22.1		 pathogenic
GRCh38/hg38 7q22.1(chr7:99219420-100902269)x1 copy number loss See cases [RCV000054154] Chr7:99219420..100902269 [GRCh38]
Chr7:98817043..100499889 [GRCh37]
Chr7:98654979..100337825 [NCBI36]
Chr7:7q22.1		 pathogenic
GRCh38/hg38 7q22.1(chr7:100419914-102482826)x1 copy number loss See cases [RCV000054155] Chr7:100419914..102482826 [GRCh38]
Chr7:100017537..102123273 [GRCh37]
Chr7:99855473..101910278 [NCBI36]
Chr7:7q22.1		 pathogenic
NM_001040097.1(MOSPD3):c.457C>T (p.Arg153Cys) single nucleotide variant Malignant melanoma [RCV000067522] Chr7:100613652 [GRCh38]
Chr7:100211275 [GRCh37]
Chr7:100049211 [NCBI36]
Chr7:7q22.1		 not provided
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q22.1(chr7:99195836-102258175)x1 copy number loss See cases [RCV000135782] Chr7:99195836..102258175 [GRCh38]
Chr7:98793459..101718950 [GRCh37]
Chr7:98631395..101688175 [NCBI36]
Chr7:7q22.1		 pathogenic|uncertain significance
GRCh38/hg38 7q21.3-36.3(chr7:97419852-158923762)x3 copy number gain See cases [RCV000136717] Chr7:97419852..158923762 [GRCh38]
Chr7:97049164..158716453 [GRCh37]
Chr7:96887100..158409214 [NCBI36]
Chr7:7q21.3-36.3		 pathogenic
GRCh38/hg38 7q22.1(chr7:99932610-102473188)x3 copy number gain See cases [RCV000138109] Chr7:99932610..102473188 [GRCh38]
Chr7:99530233..102113635 [GRCh37]
Chr7:99368169..101900640 [NCBI36]
Chr7:7q22.1		 uncertain significance
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q22.1-36.3(chr7:98969247-159119707)x3 copy number gain See cases [RCV000447709] Chr7:98969247..159119707 [GRCh37]
Chr7:7q22.1-36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q22.1(chr7:98847725-102472176)x1 copy number loss not provided [RCV000682904] Chr7:98847725..102472176 [GRCh37]
Chr7:7q22.1		 pathogenic
GRCh37/hg19 7q22.1-36.3(chr7:98693388-159119707)x3 copy number gain not provided [RCV000682911] Chr7:98693388..159119707 [GRCh37]
Chr7:7q22.1-36.3		 pathogenic
NC_000007.13:g.(20954043_21001537)_(114528369_114556605)inv inversion Childhood apraxia of speech [RCV000234948] Chr7:21001537..114528369 [GRCh37]
Chr7:7p15.3-q31.1		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q22.1(chr7:100141861-100552714)x1 copy number loss not provided [RCV000746918] Chr7:100141861..100552714 [GRCh37]
Chr7:7q22.1		 likely benign
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NM_023948.5(MOSPD3):c.13G>A (p.Ala5Thr) single nucleotide variant Inborn genetic diseases [RCV003241928] Chr7:100612804 [GRCh38]
Chr7:100210427 [GRCh37]
Chr7:7q22.1		 uncertain significance
GRCh37/hg19 7q22.1(chr7:99593346-102470275)x1 copy number loss See cases [RCV001195072] Chr7:99593346..102470275 [GRCh37]
Chr7:7q22.1		 likely pathogenic
Single allele complex Ring chromosome 7 [RCV002280646] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q21.12-22.1(chr7:87477185-100333327) copy number gain Isolated Pierre-Robin syndrome [RCV001352649] Chr7:87477185..100333327 [GRCh37]
Chr7:7q21.12-22.1		 pathogenic
GRCh37/hg19 7q22.1-31.1(chr7:99417471-111586308) copy number loss not specified [RCV002053711] Chr7:99417471..111586308 [GRCh37]
Chr7:7q22.1-31.1		 pathogenic
NC_000007.13:g.(?_98983338)_(100860555_?)del deletion not provided [RCV001877526] Chr7:98983338..100860555 [GRCh37]
Chr7:7q22.1		 pathogenic|uncertain significance
NC_000007.13:g.(?_98507659)_(100860555_?)dup duplication not provided [RCV003113282] Chr7:98507659..100860555 [GRCh37]
Chr7:7q22.1		 uncertain significance
GRCh37/hg19 7p22.3-q36.3(chr7:56604613-96692931)x1 copy number loss See cases [RCV002287832] Chr7:56604613..96692931 [GRCh37]
Chr7:7p22.3-q36.3		 uncertain significance
NM_023948.5(MOSPD3):c.79C>A (p.Pro27Thr) single nucleotide variant Inborn genetic diseases [RCV002969051] Chr7:100612870 [GRCh38]
Chr7:100210493 [GRCh37]
Chr7:7q22.1		 uncertain significance
NM_023948.5(MOSPD3):c.50C>G (p.Pro17Arg) single nucleotide variant Inborn genetic diseases [RCV002822287] Chr7:100612841 [GRCh38]
Chr7:100210464 [GRCh37]
Chr7:7q22.1		 uncertain significance
NM_023948.5(MOSPD3):c.458G>A (p.Arg153His) single nucleotide variant Inborn genetic diseases [RCV002739850] Chr7:100613653 [GRCh38]
Chr7:100211276 [GRCh37]
Chr7:7q22.1		 likely benign
NM_023948.5(MOSPD3):c.173A>G (p.Tyr58Cys) single nucleotide variant Inborn genetic diseases [RCV002916485] Chr7:100612964 [GRCh38]
Chr7:100210587 [GRCh37]
Chr7:7q22.1		 uncertain significance
NM_023948.5(MOSPD3):c.331C>A (p.Arg111Ser) single nucleotide variant Inborn genetic diseases [RCV002719493] Chr7:100613526 [GRCh38]
Chr7:100211149 [GRCh37]
Chr7:7q22.1		 uncertain significance
NM_023948.5(MOSPD3):c.535A>G (p.Ser179Gly) single nucleotide variant Inborn genetic diseases [RCV002896389] Chr7:100614890 [GRCh38]
Chr7:100212513 [GRCh37]
Chr7:7q22.1		 uncertain significance
NM_023948.5(MOSPD3):c.40C>G (p.Pro14Ala) single nucleotide variant Inborn genetic diseases [RCV002855143] Chr7:100612831 [GRCh38]
Chr7:100210454 [GRCh37]
Chr7:7q22.1		 uncertain significance
NM_023948.5(MOSPD3):c.118G>A (p.Asp40Asn) single nucleotide variant Inborn genetic diseases [RCV003208789] Chr7:100612909 [GRCh38]
Chr7:100210532 [GRCh37]
Chr7:7q22.1		 uncertain significance
NM_023948.5(MOSPD3):c.233C>T (p.Thr78Met) single nucleotide variant Inborn genetic diseases [RCV003310087] Chr7:100613221 [GRCh38]
Chr7:100210844 [GRCh37]
Chr7:7q22.1		 uncertain significance
GRCh38/hg38 7q22.1(chr7:98454022-100723798)x1 copy number loss Multiple congenital anomalies/dysmorphic syndrome [RCV003327701] Chr7:98454022..100723798 [GRCh38]
Chr7:7q22.1		 pathogenic
NM_023948.5(MOSPD3):c.65G>A (p.Arg22Gln) single nucleotide variant Inborn genetic diseases [RCV003352068] Chr7:100612856 [GRCh38]
Chr7:100210479 [GRCh37]
Chr7:7q22.1		 uncertain significance
GRCh37/hg19 7q22.1(chr7:99114000-101878272)x1 copy number loss not provided [RCV003482971] Chr7:99114000..101878272 [GRCh37]
Chr7:7q22.1		 pathogenic
GRCh37/hg19 7q22.1(chr7:98396469-102108193)x1 copy number loss not specified [RCV003986701] Chr7:98396469..102108193 [GRCh37]
Chr7:7q22.1		 likely pathogenic
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2685
Count of miRNA genes:695
Interacting mature miRNAs:838
Transcripts:ENST00000223054, ENST00000379527, ENST00000393950, ENST00000424091, ENST00000462372, ENST00000490309, ENST00000493970, ENST00000497456
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH102269  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377100,212,602 - 100,212,899UniSTSGRCh37
Build 367100,050,538 - 100,050,835RGDNCBI36
Celera794,942,383 - 94,942,680RGD
Cytogenetic Map7q22UniSTS
CRA_TCAGchr7v2799,572,233 - 99,572,530UniSTS
GeneMap99-GB4 RH Map7516.34UniSTS
MARC_26575-26576:1033748265:1  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh377100,210,535 - 100,211,143UniSTSGRCh37
Build 367100,048,471 - 100,049,079RGDNCBI36
Celera794,940,316 - 94,940,924RGD
CRA_TCAGchr7v2799,570,166 - 99,570,774UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2364 2231 1660 567 1584 411 3582 1017 3358 380 1434 1582 168 1188 2017 3
Low 75 759 66 57 367 54 775 1180 376 39 25 31 6 1 16 771 2 2
Below cutoff 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001040097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001040098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001040099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001363415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001363416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_023948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054358805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX405820 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC009482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC028475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE745548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG164079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG707362 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ923161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH236956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN256396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY025137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000223054   ⟹   ENSP00000223054
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7100,612,102 - 100,615,326 (+)Ensembl
RefSeq Acc Id: ENST00000379527   ⟹   ENSP00000368842
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7100,612,430 - 100,615,373 (+)Ensembl
RefSeq Acc Id: ENST00000393950   ⟹   ENSP00000377522
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7100,612,540 - 100,615,377 (+)Ensembl
RefSeq Acc Id: ENST00000424091   ⟹   ENSP00000404626
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7100,612,556 - 100,615,384 (+)Ensembl
RefSeq Acc Id: ENST00000462372   ⟹   ENSP00000419535
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7100,612,158 - 100,615,384 (+)Ensembl
RefSeq Acc Id: ENST00000490309
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7100,612,184 - 100,613,704 (+)Ensembl
RefSeq Acc Id: ENST00000493970   ⟹   ENSP00000417276
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7100,612,372 - 100,615,032 (+)Ensembl
RefSeq Acc Id: ENST00000497456
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl7100,612,815 - 100,613,789 (+)Ensembl
RefSeq Acc Id: NM_001040097   ⟹   NP_001035186
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387100,612,162 - 100,615,377 (+)NCBI
GRCh377100,209,725 - 100,213,003 (+)NCBI
Build 367100,047,661 - 100,050,936 (+)NCBI Archive
Celera794,939,506 - 94,942,781 (+)RGD
HuRef794,841,379 - 94,844,443 (+)ENTREZGENE
CHM1_17100,140,271 - 100,143,546 (+)NCBI
T2T-CHM13v2.07101,852,243 - 101,855,458 (+)NCBI
CRA_TCAGchr7v2799,569,356 - 99,572,631 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001040098   ⟹   NP_001035187
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387100,612,430 - 100,615,377 (+)NCBI
GRCh377100,209,725 - 100,213,003 (+)NCBI
Build 367100,047,989 - 100,050,936 (+)NCBI Archive
Celera794,939,506 - 94,942,781 (+)RGD
HuRef794,841,379 - 94,844,443 (+)ENTREZGENE
CHM1_17100,140,599 - 100,143,546 (+)NCBI
T2T-CHM13v2.07101,852,511 - 101,855,458 (+)NCBI
CRA_TCAGchr7v2799,569,356 - 99,572,631 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001040099   ⟹   NP_001035188
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387100,612,540 - 100,615,377 (+)NCBI
GRCh377100,209,725 - 100,213,003 (+)NCBI
Build 367100,048,050 - 100,050,936 (+)NCBI Archive
Celera794,939,506 - 94,942,781 (+)RGD
HuRef794,841,379 - 94,844,443 (+)ENTREZGENE
CHM1_17100,140,660 - 100,143,546 (+)NCBI
T2T-CHM13v2.07101,852,621 - 101,855,458 (+)NCBI
CRA_TCAGchr7v2799,569,356 - 99,572,631 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001363415   ⟹   NP_001350344
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387100,612,540 - 100,615,377 (+)NCBI
T2T-CHM13v2.07101,852,621 - 101,855,458 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001363416   ⟹   NP_001350345
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387100,612,382 - 100,615,377 (+)NCBI
T2T-CHM13v2.07101,852,463 - 101,855,458 (+)NCBI
Sequence:
RefSeq Acc Id: NM_023948   ⟹   NP_076438
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387100,612,540 - 100,615,377 (+)NCBI
GRCh377100,209,725 - 100,213,003 (+)NCBI
Build 367100,048,050 - 100,050,936 (+)NCBI Archive
Celera794,939,506 - 94,942,781 (+)RGD
HuRef794,841,379 - 94,844,443 (+)ENTREZGENE
CHM1_17100,140,660 - 100,143,546 (+)NCBI
T2T-CHM13v2.07101,852,621 - 101,855,458 (+)NCBI
CRA_TCAGchr7v2799,569,356 - 99,572,631 (+)ENTREZGENE
Sequence:
RefSeq Acc Id: XM_047420714   ⟹   XP_047276670
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh387100,612,466 - 100,615,377 (+)NCBI
RefSeq Acc Id: XM_054358805   ⟹   XP_054214780
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.07101,852,547 - 101,855,458 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001035186   ⟸   NM_001040097
- Peptide Label: isoform a
- UniProtKB: O75423 (UniProtKB/Swiss-Prot),   D6W5W1 (UniProtKB/Swiss-Prot),   C9JE89 (UniProtKB/Swiss-Prot),   A6NG17 (UniProtKB/Swiss-Prot),   A4D2D1 (UniProtKB/Swiss-Prot),   O75424 (UniProtKB/Swiss-Prot),   O75425 (UniProtKB/Swiss-Prot),   C9J3M4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001035187   ⟸   NM_001040098
- Peptide Label: isoform a
- UniProtKB: O75423 (UniProtKB/Swiss-Prot),   D6W5W1 (UniProtKB/Swiss-Prot),   C9JE89 (UniProtKB/Swiss-Prot),   A6NG17 (UniProtKB/Swiss-Prot),   A4D2D1 (UniProtKB/Swiss-Prot),   O75424 (UniProtKB/Swiss-Prot),   O75425 (UniProtKB/Swiss-Prot),   C9J3M4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_076438   ⟸   NM_023948
- Peptide Label: isoform a
- UniProtKB: O75423 (UniProtKB/Swiss-Prot),   D6W5W1 (UniProtKB/Swiss-Prot),   C9JE89 (UniProtKB/Swiss-Prot),   A6NG17 (UniProtKB/Swiss-Prot),   A4D2D1 (UniProtKB/Swiss-Prot),   O75424 (UniProtKB/Swiss-Prot),   O75425 (UniProtKB/Swiss-Prot),   C9J3M4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001035188   ⟸   NM_001040099
- Peptide Label: isoform b
- UniProtKB: C9J3M4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001350345   ⟸   NM_001363416
- Peptide Label: isoform a
- UniProtKB: O75425 (UniProtKB/Swiss-Prot),   O75423 (UniProtKB/Swiss-Prot),   D6W5W1 (UniProtKB/Swiss-Prot),   C9JE89 (UniProtKB/Swiss-Prot),   A6NG17 (UniProtKB/Swiss-Prot),   A4D2D1 (UniProtKB/Swiss-Prot),   O75424 (UniProtKB/Swiss-Prot),   C9J3M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001350344   ⟸   NM_001363415
- Peptide Label: isoform a
- UniProtKB: O75425 (UniProtKB/Swiss-Prot),   O75423 (UniProtKB/Swiss-Prot),   D6W5W1 (UniProtKB/Swiss-Prot),   C9JE89 (UniProtKB/Swiss-Prot),   A6NG17 (UniProtKB/Swiss-Prot),   A4D2D1 (UniProtKB/Swiss-Prot),   O75424 (UniProtKB/Swiss-Prot),   C9J3M4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSP00000404626   ⟸   ENST00000424091
RefSeq Acc Id: ENSP00000417276   ⟸   ENST00000493970
RefSeq Acc Id: ENSP00000368842   ⟸   ENST00000379527
RefSeq Acc Id: ENSP00000377522   ⟸   ENST00000393950
RefSeq Acc Id: ENSP00000223054   ⟸   ENST00000223054
RefSeq Acc Id: ENSP00000419535   ⟸   ENST00000462372
RefSeq Acc Id: XP_047276670   ⟸   XM_047420714
- Peptide Label: isoform X1
- UniProtKB: O75425 (UniProtKB/Swiss-Prot),   O75423 (UniProtKB/Swiss-Prot),   D6W5W1 (UniProtKB/Swiss-Prot),   C9JE89 (UniProtKB/Swiss-Prot),   A6NG17 (UniProtKB/Swiss-Prot),   A4D2D1 (UniProtKB/Swiss-Prot),   O75424 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_054214780   ⟸   XM_054358805
- Peptide Label: isoform X1
- UniProtKB: O75425 (UniProtKB/Swiss-Prot),   O75423 (UniProtKB/Swiss-Prot),   D6W5W1 (UniProtKB/Swiss-Prot),   C9JE89 (UniProtKB/Swiss-Prot),   A6NG17 (UniProtKB/Swiss-Prot),   A4D2D1 (UniProtKB/Swiss-Prot),   O75424 (UniProtKB/Swiss-Prot)
Protein Domains
MSP

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O75425-F1-model_v2 AlphaFold O75425 1-235 view protein structure

Promoters
RGD ID:6805927
Promoter ID:HG_KWN:58955
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000393953,   NM_001040097,   NM_001040098,   NM_001040099,   NM_023948
Position:
Human AssemblyChrPosition (strand)Source
Build 367100,047,539 - 100,048,039 (+)MPROMDB
RGD ID:7211389
Promoter ID:EPDNEW_H11440
Type:initiation region
Name:MOSPD3_2
Description:motile sperm domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11441  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh387100,612,185 - 100,612,245EPDNEW
RGD ID:7211391
Promoter ID:EPDNEW_H11441
Type:initiation region
Name:MOSPD3_1
Description:motile sperm domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11440  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh387100,612,540 - 100,612,600EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:25078 AgrOrtholog
COSMIC MOSPD3 COSMIC
Ensembl Genes ENSG00000106330 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000223054 ENTREZGENE
  ENST00000223054.8 UniProtKB/Swiss-Prot
  ENST00000379527 ENTREZGENE
  ENST00000379527.6 UniProtKB/Swiss-Prot
  ENST00000393950 ENTREZGENE
  ENST00000393950.7 UniProtKB/Swiss-Prot
  ENST00000424091 ENTREZGENE
  ENST00000424091.2 UniProtKB/Swiss-Prot
  ENST00000462372.5 UniProtKB/TrEMBL
  ENST00000493970.5 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000106330 GTEx
HGNC ID HGNC:25078 ENTREZGENE
Human Proteome Map MOSPD3 Human Proteome Map
InterPro Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOSPD1/3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MSP_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PapD-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:64598 UniProtKB/Swiss-Prot
NCBI Gene 64598 ENTREZGENE
OMIM 609125 OMIM
PANTHER MOTILE SPERM DOMAIN-CONTAINING PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MOTILE SPERM DOMAIN-CONTAINING PROTEIN 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Motile_Sperm UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA134865874 PharmGKB
PROSITE MSP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF49354 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A4D2D1 ENTREZGENE
  A6NG17 ENTREZGENE
  C9J3M4 ENTREZGENE, UniProtKB/TrEMBL
  C9JE89 ENTREZGENE
  D6W5W1 ENTREZGENE
  F8WF07_HUMAN UniProtKB/TrEMBL
  MSPD3_HUMAN UniProtKB/Swiss-Prot
  O75423 ENTREZGENE
  O75424 ENTREZGENE
  O75425 ENTREZGENE
UniProt Secondary A4D2D1 UniProtKB/Swiss-Prot
  A6NG17 UniProtKB/Swiss-Prot
  C9JE89 UniProtKB/Swiss-Prot
  D6W5W1 UniProtKB/Swiss-Prot
  O75423 UniProtKB/Swiss-Prot
  O75424 UniProtKB/Swiss-Prot