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Gene: Atoh7 (atonal bHLH transcription factor 7) Mus musculus

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Symbol:

Atoh7

Name:

atonal bHLH transcription factor 7

RGD ID:

1312699

MGI Page

MGI

Description:

Enables transcription cis-regulatory region binding activity. Involved in several processes, including entrainment of circadian clock by photoperiod; positive regulation of retinal ganglion cell axon guidance; and response to auditory stimulus. Acts upstream of or within circadian rhythm; entrainment of circadian clock; and neural retina development. Located in axon; nucleus; and perikaryon. Is expressed in several structures, including central nervous system; dorsal root ganglion; genitourinary system; liver; and retina. Human ortholog(s) of this gene implicated in persistent hyperplastic primary vitreous. Orthologous to human ATOH7 (atonal bHLH transcription factor 7).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

atonal homolog 7; bHLHa; bHLHa13; helix-loop-helix protein mATH-5; Math; Math5; protein atonal homolog 7; transcription factor Atoh7

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ATOH7 (atonal bHLH transcription factor 7)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Atoh7 (atonal bHLH transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Atoh7 (atonal bHLH transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ATOH7 (atonal bHLH transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ATOH7 (atonal bHLH transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Atoh7 (atonal bHLH transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ATOH7 (atonal bHLH transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ATOH7 (atonal bHLH transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Atoh7 (atonal bHLH transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Rattus rattus (black rat):	Atoh7 (atonal bHLH transcription factor 7)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Atoh7 (atonal bHLH transcription factor 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ATOH7 (atonal bHLH transcription factor 7)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	atoh7 (atonal bHLH transcription factor 7)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid\|ZFIN)
Drosophila melanogaster (fruit fly):	amos	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	amos	Alliance	DIOPT (Ensembl Compara\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	lin-32	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Drosophila melanogaster (fruit fly):	ato	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	atoh7	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	62,935,564 - 62,937,059 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	62,935,430 - 62,937,058 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	63,099,785 - 63,101,280 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	63,099,651 - 63,101,279 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	62,562,904 - 62,563,353 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	62,495,513 - 62,495,962 (+)	NCBI		MGSCv36	mm8
Celera	10	64,200,808 - 64,201,424 (+)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	32.54	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Foveal Hypoplasia (ISO)

Persistent Hyperplastic Primary Vitreous, Autosomal Recessive (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

3,4-methylenedioxymethamphetamine (EXP)

4,4'-diaminodiphenylmethane (EXP)

6-propyl-2-thiouracil (ISO)

aflatoxin B1 (ISO)

benzo[a]pyrene (EXP,ISO)

bis(2-chloroethyl) sulfide (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (ISO)

CGP 52608 (ISO)

chlorpyrifos (EXP)

dorsomorphin (ISO)

folic acid (EXP)

genistein (EXP)

glycidol (ISO)

methimazole (ISO)

pyridaben (EXP)

SB 431542 (ISO)

Soman (ISO)

trichloroethene (ISO)

trichostatin A (ISO)

triclosan (ISO)

triptonide (EXP)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon development (IBA)

cell differentiation (IEA)

circadian rhythm (IMP)

entrainment of circadian clock (IMP)

entrainment of circadian clock by photoperiod (IMP)

nervous system development (IEA)

neural retina development (IEA,IMP,ISO)

neuron fate commitment (IBA)

optic nerve development (IEA,ISO)

positive regulation of retinal ganglion cell axon guidance (IMP)

positive regulation of transcription by RNA polymerase II (IBA,IEA,ISO)

regulation of DNA-templated transcription (IEA)

regulation of transcription by RNA polymerase II (IMP)

response to auditory stimulus (IMP)

sensory organ development (IBA)

system development (IEA)

Cellular Component

axon (IDA,IEA)

centriole (IEA,ISO)

cytosol (IEA,ISO)

nucleoplasm (IEA,ISO)

nucleus (IBA,IEA,IMP,ISO)

perikaryon (IDA,IEA)

sperm midpiece (IEA,ISO)

Molecular Function

DNA binding (IEA)

DNA-binding transcription factor activity, RNA polymerase II-specific (IBA)

E-box binding (IBA)

protein binding (ISO)

protein dimerization activity (IEA)

sequence-specific double-stranded DNA binding (IEA,ISO)

transcription cis-regulatory region binding (IDA,IEA,ISO)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal amacrine cell morphology (IAGP)

abnormal blood vessel morphology (IAGP)

abnormal cell cycle (IAGP)

abnormal circardian behavior entrainment (IAGP)

abnormal eye development (IAGP)

abnormal eye electrophysiology (IAGP)

abnormal Muller cell morphology (IAGP)

abnormal optic nerve innervation (IAGP)

abnormal optic nerve morphology (IAGP)

abnormal optic vesicle formation (IAGP)

abnormal retina bipolar cell morphology (IAGP)

abnormal retina cone bipolar cell morphology (IAGP)

abnormal retina cone cell morphology (IAGP)

abnormal retina development (IAGP)

abnormal retina ganglion cell morphology (IAGP)

abnormal retina ganglion layer morphology (IAGP)

abnormal retina morphology (IAGP)

abnormal retina nerve fiber layer morphology (IAGP)

abnormal retina neuronal layer morphology (IAGP)

abnormal retina progenitor cell morphology (IAGP)

abnormal retina rod bipolar cell morphology (IAGP)

abnormal retina vasculature morphology (IAGP)

abnormal rod electrophysiology (IAGP)

abnormal sensory neuron innervation pattern (IAGP)

absent optic nerve (IAGP)

absent optic tract (IAGP)

absent retina ganglion cell (IAGP)

absent retina ganglion layer (IAGP)

decreased amacrine cell number (IAGP)

decreased optic chiasm size (IAGP)

decreased retina ganglion cell number (IAGP)

decreased retina rod cell number (IAGP)

decreased total retina thickness (IAGP)

increased amacrine cell number (IAGP)

increased retina apoptosis (IAGP)

increased retina cone cell number (IAGP)

increased retina photoreceptor cell number (IAGP)

no abnormal phenotype detected (IAGP)

optic nerve hypoplasia (IAGP)

retina hypoplasia (IAGP)

thin retina ganglion layer (IAGP)

thin retina inner nuclear layer (IAGP)

thin retina inner plexiform layer (IAGP)

thin retina outer nuclear layer (IAGP)

thin retina outer plexiform layer (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Mouse brain organization revealed through direct genome-scale TF expression analysis.	Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2.	Functional annotation of a full-length mouse cDNA collection.	Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3.	MGDs mouse GO annotations	MGD data from the GO Consortium
4.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
6.	Mouse MP Annotation Import Pipeline	RGD automated import pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:9806930	PMID:10349636	PMID:11042159	PMID:11076861	PMID:11156601	PMID:11456441	PMID:11493566	PMID:11748141	PMID:11861467	PMID:11889557	PMID:12451142
PMID:12477932	PMID:12654290	PMID:12950631	PMID:14623245	PMID:14681479	PMID:15363391	PMID:15459106	PMID:15576400	PMID:15677728	PMID:15733660	PMID:15797020	PMID:15882586
PMID:15905411	PMID:15976303	PMID:15980246	PMID:16038893	PMID:16141072	PMID:16141073	PMID:16651659	PMID:16690048	PMID:16854970	PMID:16959241	PMID:17075007	PMID:17092954
PMID:17107998	PMID:17559664	PMID:17623775	PMID:17653051	PMID:17900924	PMID:17977745	PMID:18287559	PMID:18321480	PMID:18367606	PMID:18557763	PMID:18787067	PMID:18940586
PMID:19004853	PMID:19191219	PMID:19208436	PMID:19339595	PMID:19389377	PMID:19459208	PMID:19474320	PMID:19804762	PMID:19828801	PMID:19855019	PMID:20002887	PMID:20144606
PMID:20237281	PMID:20394734	PMID:20395239	PMID:20412781	PMID:20808762	PMID:20875817	PMID:20969844	PMID:21087508	PMID:21273545	PMID:21441919	PMID:21451052	PMID:21771810
PMID:21830221	PMID:21873635	PMID:21875655	PMID:21903076	PMID:22019371	PMID:22065784	PMID:22200487	PMID:22323600	PMID:22445509	PMID:22609278	PMID:22645276	PMID:22660169
PMID:22973003	PMID:23147794	PMID:23152916	PMID:23170059	PMID:23293286	PMID:23395376	PMID:23408898	PMID:23426374	PMID:23481413	PMID:23515312	PMID:23649630	PMID:23720040
PMID:23761904	PMID:23884928	PMID:24148613	PMID:24183669	PMID:24319330	PMID:24392091	PMID:24453340	PMID:24523460	PMID:24753163	PMID:24799426	PMID:24952961	PMID:25011644
PMID:25100656	PMID:25367067	PMID:25401462	PMID:25556712	PMID:25775587	PMID:25794677	PMID:26174426	PMID:26392540	PMID:26439398	PMID:26449264	PMID:26949938	PMID:27098685
PMID:27677711	PMID:27679853	PMID:27957530	PMID:28356311	PMID:28402857	PMID:28411269	PMID:28419135	PMID:28675662	PMID:28722174	PMID:29225067	PMID:29408885	PMID:29424692
PMID:29770538	PMID:29977079	PMID:30048641	PMID:30051910	PMID:30326149	PMID:30485816	PMID:30541618	PMID:30764861	PMID:30842249	PMID:30850344	PMID:30995485	PMID:31155355
PMID:31197108	PMID:31285269	PMID:31949107	PMID:31964831	PMID:32741043	PMID:32817515	PMID:32850831	PMID:32986815	PMID:33428890	PMID:33674582	PMID:33712461	PMID:34757798
PMID:35790402	PMID:36066425	PMID:36342840	PMID:36459481	PMID:36715342	PMID:37252932	PMID:37526008	PMID:37590135	PMID:37751417	PMID:37916792	PMID:38823017	PMID:38890758
PMID:38917789	PMID:38937103	PMID:39133615	PMID:39160068	PMID:39946314

Genomics

Comparative Map Data

Atoh7
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	10	62,935,564 - 62,937,059 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	10	62,935,430 - 62,937,058 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	10	63,099,785 - 63,101,280 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	10	63,099,651 - 63,101,279 (+)	Ensembl			mm10	GRCm38
MGSCv37	10	62,562,904 - 62,563,353 (+)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	10	62,495,513 - 62,495,962 (+)	NCBI		MGSCv36	mm8
Celera	10	64,200,808 - 64,201,424 (+)	NCBI		Celera
Cytogenetic Map	10	B4	NCBI
cM Map	10	32.54	NCBI

ATOH7
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	10	68,230,595 - 68,232,113 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	10	68,230,595 - 68,232,113 (-)	Ensembl			hg38	GRCh38
GRCh37	10	69,990,352 - 69,991,870 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	10	69,660,387 - 69,661,861 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	10	69,660,389 - 69,661,861	NCBI
Celera	10	63,264,910 - 63,266,384 (-)	NCBI		Celera
Cytogenetic Map	10	q21.3	NCBI
HuRef	10	63,990,057 - 63,991,575 (-)	NCBI		HuRef
CHM1_1	10	70,272,108 - 70,273,626 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	10	69,099,395 - 69,100,913 (-)	NCBI		T2T-CHM13v2.0

Atoh7
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	20	25,529,528 - 25,529,977 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	20	25,528,906 - 25,530,368 (-)	Ensembl				GRCr8
mRatBN7.2	20	25,530,826 - 25,531,275 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	20	25,530,826 - 25,531,275 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	20	26,223,655 - 26,224,104 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	20	25,576,679 - 25,577,128 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	20	26,163,308 - 26,163,757 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	20	27,082,961 - 27,083,410 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	20	27,082,961 - 27,083,410 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	20	28,923,499 - 28,923,948 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	20	25,448,296 - 25,448,745 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	20	26,826,801 - 26,827,250 (-)	NCBI		Celera
RGSC_v3.1	20	25,462,095 - 25,462,545 (+)	NCBI
Cytogenetic Map	20	p11	NCBI

Atoh7
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955425	20,559,466 - 20,560,275 (-)	NCBI	ChiLan1.0	ChiLan1.0

ATOH7
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	8	80,393,599 - 80,395,396 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	10	80,398,922 - 80,400,717 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	10	64,714,546 - 64,716,341 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	10	67,025,107 - 67,026,148 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2

ATOH7
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	4	19,466,476 - 19,479,279 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	4	19,478,694 - 19,479,152 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	4	19,597,398 - 19,611,478 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	4	19,734,560 - 19,748,678 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	4	19,748,220 - 19,748,678 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	4	19,617,322 - 19,631,402 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	4	19,839,420 - 19,853,518 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	4	20,182,700 - 20,196,804 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Atoh7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	61,545,616 - 61,546,620 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936521	10,038,765 - 10,039,223 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936521	10,038,345 - 10,039,345 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATOH7
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	71,400,980 - 71,401,447 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	14	71,398,939 - 71,402,479 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	77,410,544 - 77,412,605 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATOH7
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	9	63,155,182 - 63,158,935 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	9	63,157,638 - 63,158,096 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666048	23,925,365 - 23,927,147 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atoh7
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624754	2,605,173 - 2,650,354 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624754	2,606,689 - 2,610,231 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Atoh7
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	18	23,588,500 - 23,589,460 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Atoh7
32 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	138
Count of miRNA genes:	125
Interacting mature miRNAs:	131
Transcripts:	ENSMUST00000044059
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300882	Ath17_m	atherosclerosis 17 (mouse)			Not determined		10	51091490	85091639	Mouse
39128215	Lwq17_m	liver weight QTL 17 (mouse)					10	12704051	84079784	Mouse
4141943	W6q6_m	weight 6 weeks QTL 6 (mouse)			Not determined			12704051	84079784	Mouse
1301787	Bsc1_m	brain size control 1 (mouse)			Not determined		10	58516969	92517096	Mouse
27226772	Tibl13_m	tibia length 13, 10 week (mouse)					10	18875748	129635869	Mouse
1357656	Hrtq3_m	heart weight QTL 3 (mouse)			Not determined		10	12704051	84079784	Mouse
14746991	Manh68_m	mandible shape 68 (mouse)					10	52280497	86280497	Mouse
26884426	Cvht1_m	cranial vault height 1, 5 week (mouse)					10	24675898	121035905	Mouse
10045641	Jckm3_m	juvenile cystic kidney modifier 3 (mouse)			Not determined		10	49848187	83848412	Mouse
4142380	W3q11_m	weight 3 weeks QTL 11 (mouse)			Not determined			12704051	84079784	Mouse
27226764	Tibl19_m	tibia length 19, 16 week (mouse)					10	39175996	129635869	Mouse
1357825	Kidpq2_m	kidney weight percentage QTL 2 (mouse)			Not determined		10	12704051	84079784	Mouse
1302150	Bbaa18_m	B.burgdorferi-associated arthritis 18 (mouse)			Not determined		10	49338012	83338157	Mouse
4142313	Angvq1_m	angiogenesis by VEGF QTL 1 (mouse)			Not determined			46720403	82491121	Mouse
1301380	Cia8_m	collagen induced arthritis QTL 8 (mouse)			Not determined		10	51493400	82491121	Mouse
1301003	Lmblgq4_m	limb length QTL 4 (mouse)			Not determined		10	21591192	68091639	Mouse
4141159	Phl2_m	progressive hearing loss 2 (mouse)			Not determined		10	47974499	70112651	Mouse
1301386	Sysbp1_m	systolic blood pressure 1 (mouse)			Not determined		10	10108265	87401095	Mouse
10045632	Heal16_m	wound healing/regeneration 16 (mouse)			Not determined		10	30974499	64974630	Mouse
1301966	Lifespan2_m	life span 2 (mouse)			Not determined		10	49848222	83848397	Mouse
26884421	Cvht5_m	cranial vault height 5, 10 week (mouse)					10	45576096	69135830	Mouse
1302067	Scc9_m	colon tumor susceptibility 9 (mouse)			Not determined		10	18259333	125575232	Mouse
26884411	Bzwq8_m	bi-zygomatic width QTL 8, 10 week (mouse)					10	44876096	115935905	Mouse
1357558	Bmch4_m	bone mechanical trait 4 (mouse)			Not determined		10	31577136	65577284	Mouse
1300597	Skull14_m	skull morphology 14 (mouse)			Not determined		10	49848187	83848412	Mouse
4142169	Pbwg16_m	postnatal body weight growth 16 (mouse)			Not determined		10	49848187	83848412	Mouse
26884403	Cvht8_m	cranial vault height 8, 16 week (mouse)					10	22875899	91035862	Mouse
26884400	Huml5_m	humerus length 5, 16 week (mouse)					10	46276096	69235830	Mouse
27095920	Pglq9_m	pelvic girdle length QTL 9, 10 week (mouse)					10	33775996	70835830	Mouse
26884407	Bzwq14_m	bi-zygomatic width QTL 14, 16 wee (mouse)					10	45476096	120635905	Mouse
1301502	Eae17_m	susceptibility to experimental allergic encephalomyelitis 17 (mouse)			Not determined		10	51091490	85091639	Mouse
1300898	Cfid_m	cystic fibrosis intestinal distress (mouse)			Not determined		10	29720403	63720483	Mouse
4141070	Ltgq1_m	liver triglyceride QTL 1 (mouse)			Not determined			41237326	75237326	Mouse
1558757	Eae34_m	experimental allergic encephalomyelitis susceptibility 34 (mouse)			Not determined		10	21408154	114217230	Mouse
38455999	Lick3_m	lick rate 3 (mouse)					10	61873031	69373082	Mouse
1357740	Obsty3_m	obesity 3 (mouse)			Not determined		10	8235478	116190980	Mouse
26884450	Sklq15_m	skull length QTL 15, 16 week (mouse)					10	59335822	122335905	Mouse
13208560	Wght9_m	weight 9 (mouse)					10	59835822	120835905	Mouse
27095911	Pglq15_m	pelvic girdle length QTL 15, 16 week (mouse)					10	39175996	129635869	Mouse
4141956	Egq7_m	early growth QTL 7 (mouse)			Not determined			12704051	84079784	Mouse
1357864	Scfpq1_m	subcutaneous fat pad percentage QTL 1 (mouse)			Not determined		10	12704051	84079784	Mouse
1357737	Hpcr2_m	hepatocarcinogen resistance 2 (mouse)			Not determined		10	49848222	83848397	Mouse
4142272	W10q5_m	weight 10 weeks QTL 5 (mouse)			Not determined			12704051	84079784	Mouse

Markers in Region

UniSTS:489204

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	10	63,100,156 - 63,100,605	UniSTS	GRCm38
MGSCv37	10	62,562,904 - 62,563,353	UniSTS	GRCm37
Celera	10	64,200,808 - 64,201,424	UniSTS
Cytogenetic Map	10	B4	UniSTS
cM Map	10	30.0	UniSTS

Atoh7

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
MGSCv37	10	62,564,128 - 62,564,758	UniSTS	GRCm37
Celera	10	64,202,199 - 64,202,829	UniSTS
Cytogenetic Map	10	B4	UniSTS
cM Map	10	30.0	UniSTS
cM Map	10	30.0	UniSTS

UniSTS:494177

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	10	63,100,061 - 63,100,633	UniSTS	GRCm38
MGSCv37	10	62,562,809 - 62,563,381	UniSTS	GRCm37
Celera	10	64,200,713 - 64,201,452	UniSTS
Cytogenetic Map	10	B4	UniSTS
cM Map	10	30.0	UniSTS

Atoh7

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	10	63,101,380 - 63,102,010	UniSTS	GRCm38
MGSCv37	10	62,564,128 - 62,564,758	UniSTS	GRCm37
Celera	10	64,202,199 - 64,202,829	UniSTS
Cytogenetic Map	10	B4	UniSTS
cM Map	10	30.0	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001364648	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_016864	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC155909	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF071223	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF418923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK005214	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC092234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BE860734	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000044059 ⟹ ENSMUSP00000039801

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	10	62,935,430 - 62,937,058 (+)	Ensembl
GRCm38.p6 Ensembl	10	63,099,651 - 63,101,279 (+)	Ensembl

Ensembl Acc Id:

ENSMUST00000219964

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	10	62,936,143 - 62,936,757 (+)	Ensembl
GRCm38.p6 Ensembl	10	63,100,364 - 63,100,978 (+)	Ensembl

RefSeq Acc Id:

NM_001364648 ⟹ NP_001351577

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	10	62,935,564 - 62,937,059 (+)	NCBI
GRCm38	10	63,099,785 - 63,101,280 (+)	NCBI

Sequence:

show sequence

GACATCTACTGCAAGCTGTCCAAACGCTCCTGACCTAGCAGAGCTTCTGGGAAGATTTCGTCAC
CCCGAAAAGCAGTCTCAGGCTTTCCCAGAGAACTGGAAAGGCTTTCTATCCCCGACCCCCAAGA
ACGATCCGCAGCAAACTGCAAGAAAGTTTCCTCCTCGTTCAACTTTACGTGTTTGGGGTGGAGT
GGGGAGGAATGACTTTTTCCTGAGCATCACTTCCACTGCATCTGGGCAAGGGAAGGGACTTCCC
AGCAGGACCCAAGCTAGGGTCCCACACAGTGTCCTCTGGCCACTGACTGACTGCACGTGAGTCG
CTCCGTCTGTGTCTTATTCACTCTTGGGAGTCCTGCAGAGCGGCAGCGTGGATGAAGTCGGCCT
GCAAACCCCACGGCCCTCCGGCGGGAGCTCGCGGCGCGCCCCCGTGCGCGGGCGCAGCCGAGCG
CGCGGTCTCGTGCGCGGGGCCCGGGCGGCTGGAGAGCGCGGCGCGCAGGCGTCTGGCGGCCAAC
GCGCGCGAGCGGCGCCGCATGCAGGGGCTGAACACGGCGTTCGACCGGCTGCGCAGGGTGGTGC
CGCAGTGGGGCCAGGACAAGAAGCTGTCCAAGTACGAGACACTGCAGATGGCGCTCAGCTACAT
CATCGCGCTCACCCGCATCCTAGCCGAAGCCGAGCGGGACTGGGTCGGGCTGCGCTGCGAGCAG
CGGGGCCGCGATCACCCCTACCTCCCTTTCCCGGGTGCTAGGCTCCAGGTTTCATGAGTGGACA
TCGCGAATGACTTTGGACTGCTGTGAAAATAATGCTCTGTTCCTTTTAGCCTAAGACAACGGGG
CTGGGGTCTAGCCGAGTTTGTAGAGGACTTGTCTTGCATGTATAAAAGTGGGGTTGAGCCCCAG
CTGCCGCTTAGGCAGAGCACGGTGATGCACGGCCTGTAATCCTAGCGTCATTCAGGAGGTGGAG
AAACATATATATTTAAATATTTAAGACCCCATGTCAAAAAAAAAAAAAAGATTGAATAAGACTG
GTACTAAACCATCAGACAGTTAGTTACCTTCTTAAACTGTGCAAGTTTGTCCCTATTGGGCGAA
GTTGTATTATGTGACTTGTTTATGTTCTGAGCAGCTACCTTGTGGTGTAAATGCATTTATGCTC
CGTATATTGTGTGTGCATGCATCAGATAGAGTAAGACTTTTTTTTCCCCCCTGGGGTCGAGGGT
TGGGGAGCTGGTAGAGTACTTGGGTATGAGCGCTCTGTATTTTTTTAACTGTACACATTAAAAT
ATAGATTTTGTAAAATA

hide sequence

RefSeq Acc Id:

NM_016864 ⟹ NP_058560

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	10	62,935,564 - 62,937,059 (+)	NCBI
GRCm38	10	63,099,785 - 63,101,280 (+)	NCBI
MGSCv37	10	62,562,904 - 62,563,353 (+)	RGD
Celera	10	64,200,808 - 64,201,424 (+)	RGD
cM Map	10		ENTREZGENE

Sequence:

show sequence

GACATCTACTGCAAGCTGTCCAAACGCTCCTGACCTAGCAGAGCTTCTGGGAAGATTTCGTCAC
CCCGAAAAGCAGTCTCAGGCTTTCCCAGAGAACTGGAAAGGCTTTCTATCCCCGACCCCCAAGA
ACGATCCGCAGCAAACTGCAAGAAAGTTTCCTCCTCGTTCAACTTTACGTGTTTGGGGTGGAGT
GGGGAGGAATGACTTTTTCCTGAGCATCACTTCCACTGCATCTGGGCAAGGGAAGGGACTTCCC
AGCAGGACCCAAGCTAGGGTCCCACACAGTGTCCTCTGGCCACTGACTGACTGCACGTGAGTCG
CTCCGTCTGTGTCTTATTCACTCTTGGGAGTCCTGCAGAGCGGCAGCGTGGATGAAGTCGGCCT
GCAAACCCCACGGCCCTCCGGCGGGAGCTCGCGGCGCGCCCCCGTGCGCGGGCGCAGCCGAGCG
CGCGGTCTCGTGCGCGGGGCCCGGGCGGCTGGAGAGCGCGGCGCGCAGGCGTCTGGCGGCCAAC
GCGCGCGAGCGGCGCCGCATGCAGGGGCTGAACACGGCGTTCGACCGGCTGCGCAGGGTGGTGC
CGCAGTGGGGCCAGGACAAGAAGCTGTCCAAGTACGAGACACTGCAGATGGCGCTCAGCTACAT
CATCGCGCTCACCCGCATCCTAGCCGAAGCCGAGCGGGACTGGGTCGGGCTGCGCTGCGAGCAG
CGGGGCCGCGATCACCCCTACCTCCCTTTCCCGGGTGCTAGGCTCCAGGTAGACCCTGAGCCCT
ATGGGCAGAGGCTCTTCGGCTTCCAGCCGGAGCCCTTCCCCATGGCCAGCTAAGCCTCGGGGCC
ATTTGGGTCTTAGGGGAGAAAACTCAATCACCTTTTCTGCTTAATTTCCTTCCCGTTTCAAACA
GGTAGATGAAATGAGTTCATTGCCTCCCTATCTCCACTTCTCTTGTGTTTTGTAGGTTTCATGA
GTGGACATCGCGAATGACTTTGGACTGCTGTGAAAATAATGCTCTGTTCCTTTTAGCCTAAGAC
AACGGGGCTGGGGTCTAGCCGAGTTTGTAGAGGACTTGTCTTGCATGTATAAAAGTGGGGTTGA
GCCCCAGCTGCCGCTTAGGCAGAGCACGGTGATGCACGGCCTGTAATCCTAGCGTCATTCAGGA
GGTGGAGAAACATATATATTTAAATATTTAAGACCCCATGTCAAAAAAAAAAAAAAGATTGAAT
AAGACTGGTACTAAACCATCAGACAGTTAGTTACCTTCTTAAACTGTGCAAGTTTGTCCCTATT
GGGCGAAGTTGTATTATGTGACTTGTTTATGTTCTGAGCAGCTACCTTGTGGTGTAAATGCATT
TATGCTCCGTATATTGTGTGTGCATGCATCAGATAGAGTAAGACTTTTTTTTCCCCCCTGGGGT
CGAGGGTTGGGGAGCTGGTAGAGTACTTGGGTATGAGCGCTCTGTATTTTTTTAACTGTACACA
TTAAAATATAGATTTTGTAAAATA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001351577	(Get FASTA)	NCBI Sequence Viewer
	NP_058560	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC68868	(Get FASTA)	NCBI Sequence Viewer
	AAH92234	(Get FASTA)	NCBI Sequence Viewer
	AAL11912	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000039801
	ENSMUSP00000039801.4
GenBank Protein	Q9Z2E5	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_058560 ⟸ NM_016864
- Peptide Label:	isoform 1
- UniProtKB:	Q9Z2E5 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MKSACKPHGPPAGARGAPPCAGAAERAVSCAGPGRLESAARRRLAANARERRRMQGLNTAFDRL RRVVPQWGQDKKLSKYETLQMALSYIIALTRILAEAERDWVGLRCEQRGRDHPYLPFPGARLQV DPEPYGQRLFGFQPEPFPMAS hide sequence

RefSeq Acc Id:	NP_001351577 ⟸ NM_001364648
- Peptide Label:	isoform 2

Ensembl Acc Id:

ENSMUSP00000039801 ⟸ ENSMUST00000044059

Protein Domains

bHLH

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9Z2E5-F1-model_v2	AlphaFold	Q9Z2E5	1-149	view protein structure

Promoters

RGD ID:

6818926

Promoter ID:

MM_KWN:4363

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Brain

Transcripts:

NM_016864, UC007FJW.1

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	10	62,562,741 - 62,563,241 (+)	MPROMDB

RGD ID:

8672168

Promoter ID:

EPDNEW_M14114

Type:

multiple initiation site

Name:

Atoh7_1

Description:

Mus musculus atonal bHLH transcription factor 7 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	10	63,100,184 - 63,100,244	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1355553	AgrOrtholog
Ensembl Genes	ENSMUSG00000036816	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSMUST00000044059	ENTREZGENE
	ENSMUST00000044059.5	UniProtKB/Swiss-Prot
Gene3D-CATH	4.10.280.10	UniProtKB/Swiss-Prot
InterPro	Atoh7	UniProtKB/Swiss-Prot
	bHLH_dom	UniProtKB/Swiss-Prot
	bHLH_transcription_factors	UniProtKB/Swiss-Prot
	HLH_DNA-bd_sf	UniProtKB/Swiss-Prot
KEGG Report	mmu:53404	UniProtKB/Swiss-Prot
MGD	MGI:1355553	ENTREZGENE
NCBI Gene	53404	ENTREZGENE
PANTHER	BASIC HELIX-LOOP-HELIX PROTEIN NEUROGENIN-RELATED	UniProtKB/Swiss-Prot
	PTHR19290:SF99	UniProtKB/Swiss-Prot
Pfam	HLH	UniProtKB/Swiss-Prot
PhenoGen	Atoh7	PhenoGen
PROSITE	BHLH	UniProtKB/Swiss-Prot
SMART	HLH	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF47459	UniProtKB/Swiss-Prot
UniProt	ATOH7_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-12-22	Atoh7	atonal bHLH transcription factor 7		atonal homolog 7 (Drosophila)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Mammalian Phenotype