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Gene: Il21r (interleukin 21 receptor) Mus musculus
Symbol: Il21r
Name: interleukin 21 receptor
Description: Exhibits cytokine receptor activity. Predicted to localize to the integral component of membrane. Human ortholog(s) of this gene implicated in several diseases, including B-cell lymphoma (multiple); autoimmune hypersensitivity disease (multiple); human immunodeficiency virus infectious disease; primary immunodeficiency disease (multiple); and vasculitis (multiple). Is expressed in lung; mandible; and orbito-sphenoid. Orthologous to human IL21R (interleukin 21 receptor); PARTICIPATES IN Jak-Stat signaling pathway; INTERACTS WITH 4,4'-sulfonyldiphenol; all-trans-retinoic acid; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: IL-21 receptor; IL-21R; interleukin-21 receptor; LR-beta; lymphocyte receptor beta; NILR; novel cytokine receptor 8; novel interleukin receptor; NR8
Homo sapiens (human) : IL21R (interleukin 21 receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il21r (interleukin 21 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il21r (interleukin 21 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : IL21R (interleukin 21 receptor)
Canis lupus familiaris (dog) : IL21R (interleukin 21 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il21r (interleukin 21 receptor)
Sus scrofa (pig) : IL21R (interleukin 21 receptor)
Chlorocebus sabaeus (African green monkey) : IL21R (interleukin 21 receptor)
Heterocephalus glaber (naked mole-rat) : Il21r (interleukin 21 receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl7125,603,429 - 125,633,570 (+)Ensembl
GRCm387125,603,252 - 125,634,397 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377132,746,943 - 132,777,084 (+)NCBIGRCm37mm9NCBIm37
MGSCv367125,394,625 - 125,424,718 (+)NCBImm8
Celera7125,462,065 - 125,492,498 (+)NCBICelera
Cytogenetic Map7 F3NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Il21r
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312688
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.