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Gene: CARD10 (caspase recruitment domain family member 10) Homo sapiens
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Symbol: CARD10
Name: caspase recruitment domain family member 10
Description: Predicted to have CARD domain binding activity. Involved in activation of NF-kappaB-inducing kinase activity; negative regulation of cell migration involved in sprouting angiogenesis; and positive regulation of protein localization to nucleus. Predicted to localize to cytoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: Bcl10 binding protein and activator of NFKB; BIMP1; CARD-containing MAGUK 3 protein; CARD-containing MAGUK protein 3; carma 3; CARMA3; caspase recruitment domain family, member 10; caspase recruitment domain-containing protein 10; MGC142219
Orthologs:
Mus musculus (house mouse) : Card10 (caspase recruitment domain family, member 10)  MGI  Alliance
Rattus norvegicus (Norway rat) : Card10 (caspase recruitment domain family, member 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Card10 (caspase recruitment domain family member 10)
Pan paniscus (bonobo/pygmy chimpanzee) : CARD10 (caspase recruitment domain family member 10)
Canis lupus familiaris (dog) : CARD10 (caspase recruitment domain family member 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Card10 (caspase recruitment domain family member 10)
Sus scrofa (pig) : CARD10 (caspase recruitment domain family member 10)
Chlorocebus sabaeus (African green monkey) : CARD10 (caspase recruitment domain family member 10)
Heterocephalus glaber (naked mole-rat) : Card10 (caspase recruitment domain family member 10)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2237,490,362 - 37,519,542 (-)EnsemblGRCh38hg38GRCh38
GRCh382237,490,362 - 37,519,415 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372237,886,400 - 37,915,543 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362236,216,346 - 36,245,156 (-)NCBINCBI36hg18NCBI36
Build 342236,210,900 - 36,239,710NCBI
Celera2221,687,204 - 21,715,894 (-)NCBI
Cytogenetic Map22q13.1NCBI
HuRef2220,852,627 - 20,881,868 (-)NCBIHuRef
CHM1_12237,845,198 - 37,873,529 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CARD10
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312685
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.