CDC27 (cell division cycle 27) - Rat Genome Database

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Gene: CDC27 (cell division cycle 27) Homo sapiens
Analyze
Symbol: CDC27
Name: cell division cycle 27
RGD ID: 1312639
HGNC Page HGNC:1728
Description: Enables protein phosphatase binding activity. Involved in protein K11-linked ubiquitination. Acts upstream of or within metaphase/anaphase transition of mitotic cell cycle. Located in cytoplasm; microtubule cytoskeleton; and nucleoplasm. Part of anaphase-promoting complex.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ANAPC3; anaphase promoting complex subunit 3; anaphase-promoting complex subunit 3; anaphase-promoting complex, protein 3; APC3; CDC27 homolog; CDC27Hs; cell division cycle 27 homolog; cell division cycle protein 27 homolog; D0S1430E; D0S1430E, D17S978E; D17S978E; H-NUC; HNUC; NUC2; nuc2 homolog
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: CDC27P1   CDC27P2   LOC100286895  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381747,117,703 - 47,189,295 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1747,117,703 - 47,189,422 (-)EnsemblGRCh38hg38GRCh38
GRCh371745,195,069 - 45,266,661 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361742,552,625 - 42,621,664 (-)NCBINCBI36Build 36hg18NCBI36
Build 341742,552,624 - 42,621,664NCBI
Celera1741,645,340 - 41,716,724 (-)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1740,572,496 - 40,644,750 (-)NCBIHuRef
CHM1_11745,260,254 - 45,331,607 (-)NCBICHM1_1
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (EXP)
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (EXP)
all-trans-retinoic acid  (EXP)
ammonium chloride  (ISO)
aristolochic acid A  (EXP)
arsenous acid  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[e]pyrene  (EXP)
bisphenol A  (ISO)
cadmium dichloride  (EXP)
caffeine  (EXP)
CGP 52608  (EXP)
chlorpyrifos  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
coumarin  (EXP)
coumestrol  (EXP)
cyclosporin A  (EXP)
diarsenic trioxide  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP)
Enterolactone  (EXP)
folic acid  (ISO)
formaldehyde  (EXP)
FR900359  (EXP)
geldanamycin  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (EXP)
lead(0)  (EXP)
methapyrilene  (EXP)
methyl methanesulfonate  (EXP)
motexafin gadolinium  (EXP)
N-methyl-4-phenylpyridinium  (EXP)
nickel dichloride  (ISO)
paclitaxel  (EXP)
paracetamol  (EXP,ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP)
pirinixic acid  (ISO)
potassium chromate  (EXP)
potassium dichromate  (EXP)
pravastatin  (ISO)
quercetin  (EXP)
resveratrol  (EXP,ISO)
SB 431542  (EXP)
sodium arsenite  (EXP)
sodium fluoride  (ISO)
tert-butyl hydroperoxide  (EXP)
testosterone  (ISO)
thimerosal  (EXP)
thioacetamide  (ISO)
trichostatin A  (EXP)
tunicamycin  (ISO)
valproic acid  (EXP,ISO)
vitamin E  (EXP)
vorinostat  (EXP)
zaragozic acid A  (ISO)
zinc acetate  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
anaphase-promoting complex  (IBA,IDA,IEA,IPI,NAS)
centrosome  (IDA)
cytoplasm  (IBA,IDA,IEA)
cytoskeleton  (IEA)
cytosol  (TAS)
membrane  (IEA)
mitotic spindle  (IDA)
nucleoplasm  (IDA,TAS)
nucleus  (IDA,IEA)
spindle  (IDA,IEA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7736578   PMID:7756179   PMID:8234252   PMID:8619132   PMID:9356466   PMID:9405394   PMID:9469815   PMID:9499405   PMID:9618490   PMID:9628895   PMID:9637688   PMID:9734353  
PMID:9736712   PMID:9811605   PMID:10037602   PMID:10318877   PMID:10477750   PMID:10498862   PMID:10500174   PMID:10548110   PMID:10793135   PMID:10922056   PMID:10939594   PMID:11076961  
PMID:11256614   PMID:11285280   PMID:11340163   PMID:11524682   PMID:11535616   PMID:11691834   PMID:11707408   PMID:11742988   PMID:12070128   PMID:12097298   PMID:12196507   PMID:12429948  
PMID:12477932   PMID:12686615   PMID:12797865   PMID:12853486   PMID:12956947   PMID:14561775   PMID:14593737   PMID:14657031   PMID:15029244   PMID:15082755   PMID:15252450   PMID:15280373  
PMID:15342556   PMID:15489334   PMID:15678131   PMID:15916961   PMID:15923616   PMID:16344560   PMID:16364912   PMID:16479161   PMID:16510875   PMID:16565220   PMID:16648845   PMID:16921029  
PMID:17187060   PMID:17360335   PMID:17403670   PMID:17443180   PMID:17443186   PMID:17474147   PMID:17609108   PMID:17679094   PMID:17719540   PMID:17827148   PMID:17895985   PMID:17942546  
PMID:18029348   PMID:18059335   PMID:18372912   PMID:18445686   PMID:18471975   PMID:18485873   PMID:18573889   PMID:18662541   PMID:18722180   PMID:18794143   PMID:18997788   PMID:19098431  
PMID:19483727   PMID:19490893   PMID:19531213   PMID:19615732   PMID:19822757   PMID:19826003   PMID:20054826   PMID:20081372   PMID:20212161   PMID:20360068   PMID:20395298   PMID:20439707  
PMID:20467437   PMID:20508983   PMID:20663873   PMID:20686030   PMID:20729194   PMID:20733051   PMID:20733055   PMID:20802534   PMID:20937767   PMID:20951947   PMID:21043528   PMID:21186364  
PMID:21209074   PMID:21241890   PMID:21300909   PMID:21335556   PMID:21336306   PMID:21454540   PMID:21454660   PMID:21525009   PMID:21549307   PMID:21596315   PMID:21700221   PMID:21743465  
PMID:21768287   PMID:21772247   PMID:21873635   PMID:21926987   PMID:21986944   PMID:21988832   PMID:22014574   PMID:22045814   PMID:22100920   PMID:22139841   PMID:22193957   PMID:22280307  
PMID:22539978   PMID:22792066   PMID:22939629   PMID:22942284   PMID:22990118   PMID:23007648   PMID:23007861   PMID:23022380   PMID:23029392   PMID:23078409   PMID:23160376   PMID:23239745  
PMID:23265383   PMID:23287467   PMID:23383273   PMID:23443559   PMID:23508102   PMID:23583778   PMID:23643811   PMID:23670162   PMID:23708001   PMID:23754430   PMID:23755904   PMID:23776205  
PMID:23874428   PMID:23923534   PMID:23972993   PMID:23979597   PMID:24073851   PMID:24100295   PMID:24163370   PMID:24169447   PMID:24239288   PMID:24302728   PMID:24324762   PMID:24464857  
PMID:24576404   PMID:24699064   PMID:24781523   PMID:24811168   PMID:25012665   PMID:25043029   PMID:25156254   PMID:25161877   PMID:25246557   PMID:25306918   PMID:25306923   PMID:25368385  
PMID:25375378   PMID:25383541   PMID:25416956   PMID:25490258   PMID:25544563   PMID:25609649   PMID:25659891   PMID:25673878   PMID:25680405   PMID:25723520   PMID:25750436   PMID:25852190  
PMID:25921289   PMID:25943633   PMID:26083744   PMID:26186194   PMID:26299517   PMID:26344197   PMID:26496610   PMID:26673895   PMID:26811472   PMID:26882976   PMID:26960431   PMID:26963853  
PMID:26972000   PMID:26986935   PMID:27097363   PMID:27107014   PMID:27114510   PMID:27120157   PMID:27173435   PMID:27312068   PMID:27974673   PMID:28004426   PMID:28257844   PMID:28404789  
PMID:28514442   PMID:28813667   PMID:29229926   PMID:29432156   PMID:29467282   PMID:29509190   PMID:29549242   PMID:29568061   PMID:29700288   PMID:29863498   PMID:30021884   PMID:30033366  
PMID:30308498   PMID:30341343   PMID:30463901   PMID:30498084   PMID:30554943   PMID:30804502   PMID:31006538   PMID:31024071   PMID:31091453   PMID:31239290   PMID:31527615   PMID:31753913  
PMID:32076268   PMID:32129710   PMID:32152539   PMID:32345958   PMID:32687490   PMID:32707033   PMID:32710728   PMID:32934012   PMID:33259899   PMID:33306668   PMID:33545068   PMID:33705438  
PMID:33711283   PMID:33742100   PMID:33961781   PMID:34011540   PMID:34079125   PMID:34091597   PMID:34162889   PMID:34244565   PMID:34373451   PMID:34591612   PMID:34775484   PMID:34831298  
PMID:34942119   PMID:35013429   PMID:35032548   PMID:35182466   PMID:35241646   PMID:35256949   PMID:35271311   PMID:35418986   PMID:35440621   PMID:35509820   PMID:35561648   PMID:35831314  
PMID:35944360   PMID:35952650   PMID:36089195   PMID:36114006   PMID:36215168   PMID:36232890   PMID:36517590   PMID:36520528   PMID:36736316   PMID:37827155  


Genomics

Comparative Map Data
CDC27
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381747,117,703 - 47,189,295 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1747,117,703 - 47,189,422 (-)EnsemblGRCh38hg38GRCh38
GRCh371745,195,069 - 45,266,661 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361742,552,625 - 42,621,664 (-)NCBINCBI36Build 36hg18NCBI36
Build 341742,552,624 - 42,621,664NCBI
Celera1741,645,340 - 41,716,724 (-)NCBICelera
Cytogenetic Map17q21.32NCBI
HuRef1740,572,496 - 40,644,750 (-)NCBIHuRef
CHM1_11745,260,254 - 45,331,607 (-)NCBICHM1_1
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBIT2T-CHM13v2.0
Cdc27
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3911104,393,350 - 104,441,371 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl11104,393,571 - 104,441,446 (-)EnsemblGRCm39 Ensembl
GRCm3811104,502,524 - 104,550,620 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl11104,502,745 - 104,550,620 (-)EnsemblGRCm38mm10GRCm38
MGSCv3711104,363,838 - 104,411,934 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3611104,318,606 - 104,376,937 (-)NCBIMGSCv36mm8
Celera11116,230,588 - 116,278,484 (-)NCBICelera
Cytogenetic Map11E1NCBI
cM Map1167.79NCBI
Cdc27
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81089,900,676 - 89,949,770 (-)NCBIGRCr8
mRatBN7.21089,400,720 - 89,449,816 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1089,400,940 - 89,449,736 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1094,440,366 - 94,485,331 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01093,903,884 - 93,948,519 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01089,306,665 - 89,353,815 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01092,551,754 - 92,602,214 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1092,554,081 - 92,602,082 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01092,314,321 - 92,364,553 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41093,678,790 - 93,725,987 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11093,693,161 - 93,740,357 (-)NCBI
Celera1088,097,228 - 88,143,638 (-)NCBICelera
Cytogenetic Map10q32.1NCBI
Cdc27
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554789,927,871 - 10,002,020 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554789,927,871 - 10,002,020 (+)NCBIChiLan1.0ChiLan1.0
CDC27
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21917,825,006 - 17,896,577 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11719,790,590 - 19,860,083 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01710,259,194 - 10,331,011 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11710,473,516 - 10,545,549 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1710,473,646 - 10,545,549 (+)Ensemblpanpan1.1panPan2
CDC27
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.199,281,152 - 9,351,629 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl99,281,196 - 9,348,678 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha910,946,699 - 11,017,232 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0910,870,030 - 10,940,621 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl910,870,065 - 10,940,617 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.199,884,169 - 9,954,826 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0917,569,886 - 17,640,242 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0917,516,367 - 17,586,916 (-)NCBIUU_Cfam_GSD_1.0
Cdc27
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560216,432,450 - 16,493,366 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365412,700,997 - 2,762,147 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365412,700,997 - 2,762,180 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CDC27
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1216,810,910 - 16,882,269 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11216,810,868 - 16,882,271 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21216,834,050 - 16,905,448 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CDC27
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11659,497,731 - 59,564,298 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1659,497,713 - 59,564,480 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607730,209,741 - 30,276,471 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cdc27
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248492,026,425 - 2,092,857 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248492,026,433 - 2,105,626 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in CDC27
13 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 17q21.33-24.2(chr17:36449220-68170214)x3 copy number gain See cases [RCV000050957] Chr17:36449220..68170214 [GRCh38]
Chr17:48563237..65936105 [GRCh37]
Chr17:45918236..63677950 [NCBI36]
Chr17:17q21.33-24.2
pathogenic
GRCh38/hg38 17q23.2-25.3(chr17:36449220-83086677)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052483]|See cases [RCV000052483] Chr17:36449220..83086677 [GRCh38]
Chr17:58617905..81044553 [GRCh37]
Chr17:55972687..78637842 [NCBI36]
Chr17:17q23.2-25.3
pathogenic
GRCh38/hg38 17q21.31-21.33(chr17:44955325-49381173)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052480]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052480]|See cases [RCV000052480] Chr17:44955325..49381173 [GRCh38]
Chr17:43032693..47458535 [GRCh37]
Chr17:40388219..44813534 [NCBI36]
Chr17:17q21.31-21.33
pathogenic
NM_001114091.2(CDC27):c.718A>C (p.Ile240Leu) single nucleotide variant Malignant melanoma [RCV000071527] Chr17:47157037 [GRCh38]
Chr17:45234403 [GRCh37]
Chr17:42589402 [NCBI36]
Chr17:17q21.32
not provided
NM_001114091.2(CDC27):c.717A>C (p.Val239=) single nucleotide variant Malignant melanoma [RCV000071528] Chr17:47157038 [GRCh38]
Chr17:45234404 [GRCh37]
Chr17:42589403 [NCBI36]
Chr17:17q21.32
not provided
NM_001114091.2(CDC27):c.689C>A (p.Ser230Tyr) single nucleotide variant Malignant melanoma [RCV000071529] Chr17:47157066 [GRCh38]
Chr17:45234432 [GRCh37]
Chr17:42589431 [NCBI36]
Chr17:17q21.32
not provided
NM_001114091.2(CDC27):c.516T>G (p.Ser172=) single nucleotide variant Malignant melanoma [RCV000071530] Chr17:47157344 [GRCh38]
Chr17:45234710 [GRCh37]
Chr17:42589709 [NCBI36]
Chr17:17q21.32
not provided
GRCh38/hg38 17q23.1-25.1(chr17:36449220-75053130)x3 copy number gain See cases [RCV000137437] Chr17:36449220..75053130 [GRCh38]
Chr17:57595736..73049225 [GRCh37]
Chr17:54950518..70560820 [NCBI36]
Chr17:17q23.1-25.1
pathogenic
chr17:45008570..45994044 complex variant complex Ductal breast carcinoma [RCV000207217] Chr17:45008570..45994044 [GRCh37]
Chr17:17q21.32
uncertain significance
GRCh37/hg19 17q21.31-25.3(chr17:42580684-81085615)x3 copy number gain See cases [RCV000447823] Chr17:42580684..81085615 [GRCh37]
Chr17:17q21.31-25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938) copy number gain See cases [RCV000511439] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:526-81041938)x3 copy number gain See cases [RCV000512441] Chr17:526..81041938 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:8547-81060040)x3 copy number gain not provided [RCV000739324] Chr17:8547..81060040 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:7214-81058310)x3 copy number gain not provided [RCV000739320] Chr17:7214..81058310 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
GRCh37/hg19 17p13.3-q25.3(chr17:12344-81057996)x3 copy number gain not provided [RCV000739325] Chr17:12344..81057996 [GRCh37]
Chr17:17p13.3-q25.3
pathogenic
NM_001256.6(CDC27):c.858A>G (p.Pro286=) single nucleotide variant not provided [RCV000963956] Chr17:47154771 [GRCh38]
Chr17:45232137 [GRCh37]
Chr17:17q21.32
benign|likely benign
GRCh37/hg19 17q21.32(chr17:45133476-45201091)x3 copy number gain not provided [RCV000752133] Chr17:45133476..45201091 [GRCh37]
Chr17:17q21.32
benign
GRCh37/hg19 17q21.32(chr17:45214536-45249360)x3 copy number gain not provided [RCV000752134] Chr17:45214536..45249360 [GRCh37]
Chr17:17q21.32
benign
GRCh37/hg19 17q21.32(chr17:45214536-45261955)x3 copy number gain not provided [RCV000752135] Chr17:45214536..45261955 [GRCh37]
Chr17:17q21.32
benign
GRCh37/hg19 17q21.32(chr17:45214536-45281257)x3 copy number gain not provided [RCV000752136] Chr17:45214536..45281257 [GRCh37]
Chr17:17q21.32
benign
GRCh37/hg19 17q21.32(chr17:45248189-45265693)x3 copy number gain not provided [RCV000752137] Chr17:45248189..45265693 [GRCh37]
Chr17:17q21.32
benign
NM_001256.6(CDC27):c.4A>G (p.Thr2Ala) single nucleotide variant Esophageal atresia [RCV000984724] Chr17:47189169 [GRCh38]
Chr17:45266535 [GRCh37]
Chr17:17q21.32
uncertain significance
GRCh37/hg19 17q21.32(chr17:44949883-46507482) copy number gain PNPO-related disorders [RCV003236737] Chr17:44949883..46507482 [GRCh37]
Chr17:17q21.32
likely pathogenic
GRCh37/hg19 17q21.32(chr17:45080707-45281405)x3 copy number gain not provided [RCV001834253] Chr17:45080707..45281405 [GRCh37]
Chr17:17q21.32
likely benign
NM_001256.6(CDC27):c.710C>A (p.Ser237Ter) single nucleotide variant Lung cancer [RCV002465297] Chr17:47157045 [GRCh38]
Chr17:45234411 [GRCh37]
Chr17:17q21.32
pathogenic
NM_001256.6(CDC27):c.1827T>A (p.His609Gln) single nucleotide variant Hepatocellular carcinoma [RCV002302685]|Lung cancer [RCV002464576]|Small cell lung carcinoma [RCV002464575] Chr17:47137238 [GRCh38]
Chr17:45214604 [GRCh37]
Chr17:17q21.32
pathogenic
NM_001256.6(CDC27):c.714del (p.Ala238_Val239insTer) deletion Hepatocellular carcinoma [RCV002302686]|Lung cancer [RCV002464578]|Small cell lung carcinoma [RCV002464577] Chr17:47157041 [GRCh38]
Chr17:45234407 [GRCh37]
Chr17:17q21.32
pathogenic
NM_001256.6(CDC27):c.1912T>C (p.Trp638Arg) single nucleotide variant Hepatocellular carcinoma [RCV002302731]|Lung cancer [RCV002464593]|Small cell lung carcinoma [RCV002464592] Chr17:47137153 [GRCh38]
Chr17:45214519 [GRCh37]
Chr17:17q21.32
pathogenic
NM_001256.6(CDC27):c.1777G>A (p.Ala593Thr) single nucleotide variant Pulmonary artery atresia [RCV002512185] Chr17:47137288 [GRCh38]
Chr17:45214654 [GRCh37]
Chr17:17q21.32
pathogenic
NM_001256.6(CDC27):c.1758A>G (p.Ala586=) single nucleotide variant not provided [RCV003419763] Chr17:47137307 [GRCh38]
Chr17:45214673 [GRCh37]
Chr17:17q21.32
likely benign
NM_001256.6(CDC27):c.501A>T (p.Thr167=) single nucleotide variant not provided [RCV003419764] Chr17:47157359 [GRCh38]
Chr17:45234725 [GRCh37]
Chr17:17q21.32
likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:4019
Count of miRNA genes:1221
Interacting mature miRNAs:1513
Transcripts:ENST00000066544, ENST00000446365, ENST00000525495, ENST00000526866, ENST00000527547, ENST00000528147, ENST00000528748, ENST00000531206, ENST00000532575, ENST00000532893, ENST00000533415, ENST00000570740, ENST00000570818, ENST00000571643, ENST00000573502, ENST00000573550, ENST00000574304, ENST00000575483, ENST00000575830, ENST00000576484
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
STS-H82965  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,221,099 - 45,221,295UniSTSGRCh37
Build 361742,576,098 - 42,576,294RGDNCBI36
Celera1741,671,157 - 41,671,353RGD
Cytogenetic Map17q21.32UniSTS
HuRef1740,599,132 - 40,599,328UniSTS
GeneMap99-GB4 RH Map17333.0UniSTS
NCBI RH Map17598.6UniSTS
RH102849  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,195,242 - 45,195,387UniSTSGRCh37
Build 361742,550,241 - 42,550,386RGDNCBI36
Celera1741,645,272 - 41,645,417RGD
Cytogenetic Map17q21.32UniSTS
HuRef1740,572,428 - 40,572,573UniSTS
GeneMap99-GB4 RH Map17333.2UniSTS
D14S145  
Human AssemblyChrPosition (strand)SourceJBrowse
Build 362132,735,535 - 132,736,067RGDNCBI36
Celera2125,351,841 - 125,352,373RGD
Cytogenetic Map17q21.32UniSTS
Cytogenetic Map2q21.2UniSTS
AI452358  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,195,469 - 45,195,648UniSTSGRCh37
Build 361742,550,468 - 42,550,647RGDNCBI36
Celera1741,645,499 - 41,645,678RGD
HuRef1740,572,655 - 40,572,834UniSTS
RH46196  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,255,468 - 45,255,624UniSTSGRCh37
Build 361742,610,467 - 42,610,623RGDNCBI36
Celera1741,705,526 - 41,705,682RGD
Cytogenetic Map17q21.32UniSTS
HuRef1740,633,548 - 40,633,704UniSTS
GeneMap99-GB4 RH Map17337.7UniSTS
CDC27_1878  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,197,430 - 45,198,299UniSTSGRCh37
Build 361742,552,429 - 42,553,298RGDNCBI36
Celera1741,647,460 - 41,648,329RGD
HuRef1740,574,616 - 40,575,485UniSTS
WI-13636  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,195,345 - 45,195,470UniSTSGRCh37
Build 361742,550,344 - 42,550,469RGDNCBI36
Celera1741,645,375 - 41,645,500RGD
Cytogenetic Map17q21.32UniSTS
HuRef1740,572,531 - 40,572,656UniSTS
GeneMap99-GB4 RH Map17330.8UniSTS
Whitehead-RH Map17361.0UniSTS
NCBI RH Map17593.6UniSTS
T03706  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,196,924 - 45,197,107UniSTSGRCh37
Build 361742,551,923 - 42,552,106RGDNCBI36
Celera1741,646,954 - 41,647,137RGD
Cytogenetic Map17q21.32UniSTS
HuRef1740,574,110 - 40,574,293UniSTS
Whitehead-YAC Contig Map17 UniSTS
RH65445  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,262,200 - 45,262,336UniSTSGRCh37
Build 361742,617,199 - 42,617,335RGDNCBI36
Celera1741,712,258 - 41,712,394RGD
Cytogenetic Map17q21.32UniSTS
HuRef1740,640,284 - 40,640,420UniSTS
GeneMap99-GB4 RH Map17333.2UniSTS
NCBI RH Map17586.4UniSTS
L18241  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,197,126 - 45,197,273UniSTSGRCh37
Build 361742,552,125 - 42,552,272RGDNCBI36
Celera1741,647,156 - 41,647,303RGD
Cytogenetic Map17q21.32UniSTS
HuRef1740,574,312 - 40,574,459UniSTS
A007J33  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,195,378 - 45,195,535UniSTSGRCh37
Build 361742,550,377 - 42,550,534RGDNCBI36
Celera1741,645,408 - 41,645,565RGD
Cytogenetic Map17q21.32UniSTS
HuRef1740,572,564 - 40,572,721UniSTS
GeneMap99-GB4 RH Map17333.2UniSTS
NCBI RH Map17589.6UniSTS
STS-S78234  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371745,198,053 - 45,198,261UniSTSGRCh37
Build 361742,553,052 - 42,553,260RGDNCBI36
Celera1741,648,083 - 41,648,291RGD
Cytogenetic Map17q21.32UniSTS
HuRef1740,575,239 - 40,575,447UniSTS
GeneMap99-GB4 RH Map17319.05UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2021 1764 1426 335 1199 210 4022 1667 2536 303 1419 1607 141 1 1199 2545 6 2
Low 418 1226 300 289 751 255 335 530 1198 116 41 6 34 5 243
Below cutoff 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001114091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001293089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001293091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353035 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001353051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_148340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011525546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011525547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011525548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011525549 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017025481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017025484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017025485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017025486 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017025488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_024451052 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047437229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047437230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054318100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054318101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054318102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054318103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054318104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054318105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054318106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054318107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_934630 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA927469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC002558 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK296881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU135593 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY518321 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BI548077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP234964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ786193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HY023336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ411653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ411655 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ411657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S78234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U00001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000066544   ⟹   ENSP00000066544
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,117,703 - 47,189,295 (-)Ensembl
RefSeq Acc Id: ENST00000525495
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,141,844 - 47,189,261 (-)Ensembl
RefSeq Acc Id: ENST00000526866   ⟹   ENSP00000432105
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,122,552 - 47,189,264 (-)Ensembl
RefSeq Acc Id: ENST00000527547   ⟹   ENSP00000437339
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,120,880 - 47,189,224 (-)Ensembl
RefSeq Acc Id: ENST00000528147
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,181,282 - 47,189,252 (-)Ensembl
RefSeq Acc Id: ENST00000528748
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,157,060 - 47,188,936 (-)Ensembl
RefSeq Acc Id: ENST00000531206   ⟹   ENSP00000434614
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,120,255 - 47,189,176 (-)Ensembl
RefSeq Acc Id: ENST00000532575
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,157,230 - 47,189,422 (-)Ensembl
RefSeq Acc Id: ENST00000532893   ⟹   ENSP00000466424
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,157,055 - 47,189,261 (-)Ensembl
RefSeq Acc Id: ENST00000533415   ⟹   ENSP00000432211
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,120,771 - 47,189,251 (-)Ensembl
RefSeq Acc Id: ENST00000570740   ⟹   ENSP00000460830
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,120,610 - 47,123,895 (-)Ensembl
RefSeq Acc Id: ENST00000570818   ⟹   ENSP00000460061
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,154,755 - 47,172,047 (-)Ensembl
RefSeq Acc Id: ENST00000571643   ⟹   ENSP00000460279
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,120,810 - 47,137,244 (-)Ensembl
RefSeq Acc Id: ENST00000573502   ⟹   ENSP00000460132
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,137,152 - 47,142,381 (-)Ensembl
RefSeq Acc Id: ENST00000573550   ⟹   ENSP00000460424
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,154,698 - 47,181,605 (-)Ensembl
RefSeq Acc Id: ENST00000574304   ⟹   ENSP00000458904
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,142,428 - 47,169,977 (-)Ensembl
RefSeq Acc Id: ENST00000575483   ⟹   ENSP00000460454
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,156,913 - 47,189,252 (-)Ensembl
RefSeq Acc Id: ENST00000575830
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,143,883 - 47,156,715 (-)Ensembl
RefSeq Acc Id: ENST00000576484   ⟹   ENSP00000459307
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1747,151,814 - 47,157,267 (-)Ensembl
RefSeq Acc Id: NM_001114091   ⟹   NP_001107563
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
GRCh371745,195,310 - 45,266,665 (-)ENTREZGENE
HuRef1740,572,496 - 40,644,750 (-)ENTREZGENE
CHM1_11745,260,007 - 45,331,620 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001256   ⟹   NP_001247
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
GRCh371745,195,310 - 45,266,665 (-)ENTREZGENE
Build 361742,552,625 - 42,621,664 (-)NCBI Archive
HuRef1740,572,496 - 40,644,750 (-)ENTREZGENE
CHM1_11745,260,007 - 45,331,620 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001293089   ⟹   NP_001280018
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
CHM1_11745,260,007 - 45,331,620 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001293091   ⟹   NP_001280020
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
CHM1_11745,260,007 - 45,331,620 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353035   ⟹   NP_001339964
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353047   ⟹   NP_001339976
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353049   ⟹   NP_001339978
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353050   ⟹   NP_001339979
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001353051   ⟹   NP_001339980
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: NR_148340
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011525546   ⟹   XP_011523848
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011525547   ⟹   XP_011523849
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,122,445 - 47,189,295 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011525548   ⟹   XP_011523850
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011525549   ⟹   XP_011523851
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,188,882 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017025484   ⟹   XP_016880973
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017025485   ⟹   XP_016880974
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047437229   ⟹   XP_047293185
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,122,445 - 47,189,295 (-)NCBI
RefSeq Acc Id: XM_047437230   ⟹   XP_047293186
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,117,703 - 47,189,295 (-)NCBI
RefSeq Acc Id: XM_054318100   ⟹   XP_054174075
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
RefSeq Acc Id: XM_054318101   ⟹   XP_054174076
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01747,983,938 - 48,051,640 (-)NCBI
RefSeq Acc Id: XM_054318102   ⟹   XP_054174077
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01747,983,938 - 48,051,640 (-)NCBI
RefSeq Acc Id: XM_054318103   ⟹   XP_054174078
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
RefSeq Acc Id: XM_054318104   ⟹   XP_054174079
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01747,979,197 - 48,051,406 (-)NCBI
RefSeq Acc Id: XM_054318105   ⟹   XP_054174080
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
RefSeq Acc Id: XM_054318106   ⟹   XP_054174081
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
RefSeq Acc Id: XM_054318107   ⟹   XP_054174082
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01747,979,197 - 48,051,640 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001107563 (Get FASTA)   NCBI Sequence Viewer  
  NP_001247 (Get FASTA)   NCBI Sequence Viewer  
  NP_001280018 (Get FASTA)   NCBI Sequence Viewer  
  NP_001280020 (Get FASTA)   NCBI Sequence Viewer  
  NP_001339964 (Get FASTA)   NCBI Sequence Viewer  
  NP_001339976 (Get FASTA)   NCBI Sequence Viewer  
  NP_001339978 (Get FASTA)   NCBI Sequence Viewer  
  NP_001339979 (Get FASTA)   NCBI Sequence Viewer  
  NP_001339980 (Get FASTA)   NCBI Sequence Viewer  
  XP_011523848 (Get FASTA)   NCBI Sequence Viewer  
  XP_011523849 (Get FASTA)   NCBI Sequence Viewer  
  XP_011523850 (Get FASTA)   NCBI Sequence Viewer  
  XP_011523851 (Get FASTA)   NCBI Sequence Viewer  
  XP_016880973 (Get FASTA)   NCBI Sequence Viewer  
  XP_016880974 (Get FASTA)   NCBI Sequence Viewer  
  XP_047293185 (Get FASTA)   NCBI Sequence Viewer  
  XP_047293186 (Get FASTA)   NCBI Sequence Viewer  
  XP_054174075 (Get FASTA)   NCBI Sequence Viewer  
  XP_054174076 (Get FASTA)   NCBI Sequence Viewer  
  XP_054174077 (Get FASTA)   NCBI Sequence Viewer  
  XP_054174078 (Get FASTA)   NCBI Sequence Viewer  
  XP_054174079 (Get FASTA)   NCBI Sequence Viewer  
  XP_054174080 (Get FASTA)   NCBI Sequence Viewer  
  XP_054174081 (Get FASTA)   NCBI Sequence Viewer  
  XP_054174082 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA60471 (Get FASTA)   NCBI Sequence Viewer  
  AAB34378 (Get FASTA)   NCBI Sequence Viewer  
  AAH11656 (Get FASTA)   NCBI Sequence Viewer  
  AAR89911 (Get FASTA)   NCBI Sequence Viewer  
  AFI24904 (Get FASTA)   NCBI Sequence Viewer  
  AFI24906 (Get FASTA)   NCBI Sequence Viewer  
  AFI24908 (Get FASTA)   NCBI Sequence Viewer  
  BAG59442 (Get FASTA)   NCBI Sequence Viewer  
  BAG61343 (Get FASTA)   NCBI Sequence Viewer  
  EAW57686 (Get FASTA)   NCBI Sequence Viewer  
  EAW57687 (Get FASTA)   NCBI Sequence Viewer  
  EAW57688 (Get FASTA)   NCBI Sequence Viewer  
  EAW57689 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000066544
  ENSP00000066544.3
  ENSP00000432105.1
  ENSP00000432211.1
  ENSP00000434614
  ENSP00000434614.1
  ENSP00000437339
  ENSP00000437339.1
  ENSP00000458904.1
  ENSP00000459307.1
  ENSP00000460061.1
  ENSP00000460132.1
  ENSP00000460279.1
  ENSP00000460424.1
  ENSP00000460454.1
  ENSP00000460830.1
  ENSP00000466424.1
GenBank Protein P30260 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001107563   ⟸   NM_001114091
- Peptide Label: isoform 1
- UniProtKB: P30260 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001247   ⟸   NM_001256
- Peptide Label: isoform 2
- UniProtKB: Q16349 (UniProtKB/Swiss-Prot),   G3V1C4 (UniProtKB/Swiss-Prot),   Q96F35 (UniProtKB/Swiss-Prot),   P30260 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001280020   ⟸   NM_001293091
- Peptide Label: isoform 4
- UniProtKB: B4DL80 (UniProtKB/TrEMBL),   E7EN31 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001280018   ⟸   NM_001293089
- Peptide Label: isoform 3
- UniProtKB: G5EA36 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011523848   ⟸   XM_011525546
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011523849   ⟸   XM_011525547
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011523850   ⟸   XM_011525548
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011523851   ⟸   XM_011525549
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_016880974   ⟸   XM_017025485
- Peptide Label: isoform X7
- Sequence:
RefSeq Acc Id: XP_016880973   ⟸   XM_017025484
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: NP_001339979   ⟸   NM_001353050
- Peptide Label: isoform 8
- Sequence:
RefSeq Acc Id: NP_001339980   ⟸   NM_001353051
- Peptide Label: isoform 9
- Sequence:
RefSeq Acc Id: NP_001339978   ⟸   NM_001353049
- Peptide Label: isoform 7
- Sequence:
RefSeq Acc Id: NP_001339976   ⟸   NM_001353047
- Peptide Label: isoform 6
- Sequence:
RefSeq Acc Id: NP_001339964   ⟸   NM_001353035
- Peptide Label: isoform 5
- Sequence:
RefSeq Acc Id: ENSP00000460830   ⟸   ENST00000570740
RefSeq Acc Id: ENSP00000434614   ⟸   ENST00000531206
RefSeq Acc Id: ENSP00000460061   ⟸   ENST00000570818
RefSeq Acc Id: ENSP00000460279   ⟸   ENST00000571643
RefSeq Acc Id: ENSP00000466424   ⟸   ENST00000532893
RefSeq Acc Id: ENSP00000432211   ⟸   ENST00000533415
RefSeq Acc Id: ENSP00000460132   ⟸   ENST00000573502
RefSeq Acc Id: ENSP00000460424   ⟸   ENST00000573550
RefSeq Acc Id: ENSP00000458904   ⟸   ENST00000574304
RefSeq Acc Id: ENSP00000460454   ⟸   ENST00000575483
RefSeq Acc Id: ENSP00000459307   ⟸   ENST00000576484
RefSeq Acc Id: ENSP00000066544   ⟸   ENST00000066544
RefSeq Acc Id: ENSP00000432105   ⟸   ENST00000526866
RefSeq Acc Id: ENSP00000437339   ⟸   ENST00000527547
RefSeq Acc Id: XP_047293186   ⟸   XM_047437230
- Peptide Label: isoform X5
RefSeq Acc Id: XP_047293185   ⟸   XM_047437229
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054174082   ⟸   XM_054318107
- Peptide Label: isoform X7
RefSeq Acc Id: XP_054174081   ⟸   XM_054318106
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054174080   ⟸   XM_054318105
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054174078   ⟸   XM_054318103
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054174075   ⟸   XM_054318100
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054174079   ⟸   XM_054318104
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054174077   ⟸   XM_054318102
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054174076   ⟸   XM_054318101
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30260-F1-model_v2 AlphaFold P30260 1-824 view protein structure

Promoters
RGD ID:6793862
Promoter ID:HG_KWN:26442
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   CD4+TCell_2Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_001114091,   NM_001256,   UC002ILF.2
Position:
Human AssemblyChrPosition (strand)Source
Build 361742,621,321 - 42,621,967 (-)MPROMDB
RGD ID:7235387
Promoter ID:EPDNEW_H23440
Type:initiation region
Name:CDC27_1
Description:cell division cycle 27
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381747,189,271 - 47,189,331EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:1728 AgrOrtholog
COSMIC CDC27 COSMIC
Ensembl Genes ENSG00000004897 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000066544 ENTREZGENE
  ENST00000066544.8 UniProtKB/Swiss-Prot
  ENST00000526866.5 UniProtKB/TrEMBL
  ENST00000527547 ENTREZGENE
  ENST00000527547.5 UniProtKB/TrEMBL
  ENST00000531206 ENTREZGENE
  ENST00000531206.5 UniProtKB/Swiss-Prot
  ENST00000532893.5 UniProtKB/TrEMBL
  ENST00000533415.5 UniProtKB/TrEMBL
  ENST00000570740.1 UniProtKB/TrEMBL
  ENST00000570818.5 UniProtKB/TrEMBL
  ENST00000571643.5 UniProtKB/TrEMBL
  ENST00000573502.1 UniProtKB/TrEMBL
  ENST00000573550.5 UniProtKB/TrEMBL
  ENST00000574304.5 UniProtKB/TrEMBL
  ENST00000575483.5 UniProtKB/TrEMBL
  ENST00000576484.1 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000004897 GTEx
HGNC ID HGNC:1728 ENTREZGENE
Human Proteome Map CDC27 Human Proteome Map
InterPro TPR-like_helical_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:996 UniProtKB/Swiss-Prot
NCBI Gene 996 ENTREZGENE
OMIM 116946 OMIM
PANTHER CELL DIVISION CYCLE 16,23,27 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CELL DIVISION CYCLE PROTEIN 27 HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ANAPC3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA26261 PharmGKB
PROSITE TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TPR_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART TPR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48452 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt B4DL80 ENTREZGENE, UniProtKB/TrEMBL
  CDC27_HUMAN UniProtKB/Swiss-Prot
  E7EN31 ENTREZGENE
  E9PRZ6_HUMAN UniProtKB/TrEMBL
  F6QPS0_HUMAN UniProtKB/TrEMBL
  G3V1C4 ENTREZGENE
  G5EA36 ENTREZGENE, UniProtKB/TrEMBL
  I0EZ68_HUMAN UniProtKB/TrEMBL
  I0EZ72_HUMAN UniProtKB/TrEMBL
  I3L1K3_HUMAN UniProtKB/TrEMBL
  I3L225_HUMAN UniProtKB/TrEMBL
  I3L2Z8_HUMAN UniProtKB/TrEMBL
  I3L328_HUMAN UniProtKB/TrEMBL
  I3L394_HUMAN UniProtKB/TrEMBL
  I3L3G1_HUMAN UniProtKB/TrEMBL
  I3L3H6_HUMAN UniProtKB/TrEMBL
  I3L3Y5_HUMAN UniProtKB/TrEMBL
  K7EMA6_HUMAN UniProtKB/TrEMBL
  P30260 ENTREZGENE
  Q16349 ENTREZGENE
  Q96F35 ENTREZGENE
UniProt Secondary E7EN31 UniProtKB/TrEMBL
  G3V1C4 UniProtKB/Swiss-Prot
  Q16349 UniProtKB/Swiss-Prot
  Q96F35 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-29 CDC27  cell division cycle 27  CDC27  cell division cycle 27 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED