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Gene: CDC27 (cell division cycle 27) Homo sapiens
Symbol: CDC27
Name: cell division cycle 27
Description: Exhibits protein phosphatase binding activity. Involved in metaphase/anaphase transition of mitotic cell cycle and protein K11-linked ubiquitination. Localizes to the centrosome; cytoplasm; and nucleus. Colocalizes with the spindle microtubule.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ANAPC3; anaphase promoting complex subunit 3; anaphase-promoting complex subunit 3; anaphase-promoting complex, protein 3; APC3; CDC27 homolog; CDC27Hs; cell division cycle 27 homolog; cell division cycle protein 27 homolog; D0S1430E; D0S1430E, D17S978E; D17S978E; H-NUC; HNUC; NUC2; nuc2 homolog
Mus musculus (house mouse) : Cdc27 (cell division cycle 27)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cdc27 (cell division cycle 27)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cdc27 (cell division cycle 27)
Pan paniscus (bonobo/pygmy chimpanzee) : CDC27 (cell division cycle 27)
Canis lupus familiaris (dog) : CDC27 (cell division cycle 27)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cdc27 (cell division cycle 27)
Sus scrofa (pig) : CDC27 (cell division cycle 27)
more info ...
Related Pseudogenes: CDC27P1   CDC27P2  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381747,117,703 - 47,189,295 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371745,195,310 - 45,266,665 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361742,552,625 - 42,621,664 (-)NCBINCBI36hg18NCBI36
Build 341742,552,624 - 42,621,664NCBI
Celera1741,645,340 - 41,716,724 (-)NCBI
Cytogenetic Map17q21.32NCBI
HuRef1740,572,496 - 40,644,750 (-)NCBIHuRef
CHM1_11745,260,007 - 45,331,620 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CDC27
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312639
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.