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Gene: Trp53rkb (transformation related protein 53 regulating kinase B) Mus musculus
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Symbol: Trp53rkb
Name: transformation related protein 53 regulating kinase B
Description: Predicted to have p53 binding activity and protein serine/threonine kinase activity. Predicted to be involved in protein phosphorylation and tRNA threonylcarbamoyladenosine metabolic process. Predicted to localize to the EKC/KEOPS complex; cytoplasm; and nucleus. Human ortholog(s) of this gene implicated in Galloway-Mowat syndrome 4. Is expressed in central nervous system; forelimb bud; genitourinary system; liver; and retina. Orthologous to human TP53RK (TP53 regulating kinase); INTERACTS WITH bisphenol A; cadmium dichloride; Diisodecyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810408M09Rik; 4933401B08Rik; 5630401H01Rik; atypical serine/threonine protein kinase Tp53rk; EKC/KEOPS complex subunit Tp53rk; MGC2882; mNori-2p; Nori-2; p53-related protein kinase; PRPK; TP53 regulating kinase; TP53-regulating kinase; Tp53rk; Trp53 regulating kinase; Trp53rk; Trp53tk
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm382166,792,459 - 166,799,492 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv372166,619,267 - 166,624,992 (+)NCBIGRCm37mm9NCBIm37
MGSCv362166,484,972 - 166,490,697 (+)NCBImm8
Celera2172,733,223 - 172,738,948 (+)NCBICelera
Cytogenetic Map2 H3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Trp53rkb
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312622
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.