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Gene: UBE2G2 (ubiquitin conjugating enzyme E2 G2) Homo sapiens
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Symbol: UBE2G2
Name: ubiquitin conjugating enzyme E2 G2
Description: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: E2 ubiquitin-conjugating enzyme G2; UBC7; ubiquitin carrier protein G2; ubiquitin conjugating enzyme 7; ubiquitin conjugating enzyme E2G 2; ubiquitin conjugating enzyme G2; ubiquitin-conjugating enzyme E2 G2; ubiquitin-conjugating enzyme E2G 2 (homologous to yeast UBC7); ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); ubiquitin-protein ligase G2
Orthologs:
Mus musculus (house mouse) : Ube2g2 (ubiquitin-conjugating enzyme E2G 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ube2g2 (ubiquitin-conjugating enzyme E2G 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ube2g2 (ubiquitin conjugating enzyme E2 G2)
Pan paniscus (bonobo/pygmy chimpanzee) : UBE2G2 (ubiquitin conjugating enzyme E2 G2)
Canis lupus familiaris (dog) : UBE2G2 (ubiquitin conjugating enzyme E2 G2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ube2g2 (ubiquitin conjugating enzyme E2 G2)
Sus scrofa (pig) : UBE2G2 (ubiquitin conjugating enzyme E2 G2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382144,768,580 - 44,801,820 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372146,188,495 - 46,221,751 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362145,013,383 - 45,046,166 (-)NCBINCBI36hg18NCBI36
Build 342145,013,383 - 45,046,166NCBI
Celera2131,296,281 - 31,329,066 (-)NCBI
Cytogenetic Map21q22.3NCBI
HuRef2131,562,705 - 31,595,904 (-)NCBIHuRef
CHM1_12145,749,021 - 45,782,288 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on UBE2G2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312541
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-10-08
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.