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Gene: DLX2 (distal-less homeobox 2) Homo sapiens
Symbol: DLX2
Name: distal-less homeobox 2
Description: Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in regulation of neuron differentiation and regulation of transcription by RNA polymerase II. Predicted to localize to the nuclear chromatin.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: distal-less homeo box 2; homeobox protein DLX-2; TES-1; TES1
Mus musculus (house mouse) : Dlx2 (distal-less homeobox 2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dlx2 (distal-less homeobox 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dlx2 (distal-less homeobox 2)
Pan paniscus (bonobo/pygmy chimpanzee) : DLX2 (distal-less homeobox 2)
Canis lupus familiaris (dog) : DLX2 (distal-less homeobox 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dlx2 (distal-less homeobox 2)
Sus scrofa (pig) : DLX2 (distal-less homeobox 2)
Chlorocebus sabaeus (green monkey) : DLX2 (distal-less homeobox 2)
Heterocephalus glaber (naked mole-rat) : Dlx2 (distal-less homeobox 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl2172,099,438 - 172,102,900 (-)Ensembl
GRCh382172,099,438 - 172,102,900 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372172,964,166 - 172,967,478 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362172,672,412 - 172,675,724 (-)NCBINCBI36hg18NCBI36
Build 342172,789,673 - 172,792,773NCBI
Celera2166,580,267 - 166,583,579 (-)NCBI
Cytogenetic Map2q31.1NCBI
HuRef2164,844,417 - 164,847,729 (-)NCBIHuRef
CHM1_12172,971,642 - 172,974,954 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on DLX2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312529
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.