Fam136a (family with sequence similarity 136, member A) - Rat Genome Database
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Gene: Fam136a (family with sequence similarity 136, member A) Mus musculus
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Symbol: Fam136a
Name: family with sequence similarity 136, member A
RGD ID: 1312491
MGI Page MGI
Description: Is expressed in several structures, including adrenal gland; alimentary system; orbito-sphenoid; renal cortex; and respiratory system. Orthologous to human FAM136A (family with sequence similarity 136 member A); INTERACTS WITH 1,2-dimethylhydrazine; dibenzo[a,l]pyrene; dibutyl phthalate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2010309E21Rik; AW124904; Hyccin; hypothetical protein LOC66488; MGC117903
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Fam136b-ps  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,342,453 - 86,347,040 (+)NCBIGRCm39mm39
GRCm39 Ensembl686,342,628 - 86,347,040 (+)Ensembl
GRCm38686,365,471 - 86,370,058 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl686,365,646 - 86,370,058 (+)EnsemblGRCm38mm10GRCm38
MGSCv37686,315,677 - 86,320,052 (+)NCBIGRCm37mm9NCBIm37
MGSCv36686,331,317 - 86,335,692 (+)NCBImm8
Celera688,303,323 - 88,307,699 (+)NCBICelera
Cytogenetic Map6D1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
mitochondrion  (HDA)

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14610273   PMID:16141072   PMID:16141073   PMID:18614015   PMID:19515974   PMID:21267068   PMID:21677750  
PMID:21873635   PMID:32325033  


Genomics

Comparative Map Data
Fam136a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,342,453 - 86,347,040 (+)NCBIGRCm39mm39
GRCm39 Ensembl686,342,628 - 86,347,040 (+)Ensembl
GRCm38686,365,471 - 86,370,058 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl686,365,646 - 86,370,058 (+)EnsemblGRCm38mm10GRCm38
MGSCv37686,315,677 - 86,320,052 (+)NCBIGRCm37mm9NCBIm37
MGSCv36686,331,317 - 86,335,692 (+)NCBImm8
Celera688,303,323 - 88,307,699 (+)NCBICelera
Cytogenetic Map6D1NCBI
FAM136A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl270,295,975 - 70,302,090 (-)EnsemblGRCh38hg38GRCh38
GRCh38270,295,976 - 70,302,067 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37270,523,108 - 70,529,199 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36270,376,613 - 70,382,705 (-)NCBINCBI36hg18NCBI36
Celera270,373,798 - 70,379,911 (-)NCBI
Cytogenetic Map2p13.3NCBI
HuRef270,259,949 - 70,266,062 (-)NCBIHuRef
CHM1_1270,452,722 - 70,458,834 (-)NCBICHM1_1
Fam136a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24118,805,129 - 118,811,046 (+)NCBI
Rnor_6.0 Ensembl4118,160,147 - 118,166,062 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04118,160,147 - 118,166,062 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04182,731,397 - 182,737,312 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44120,541,766 - 120,547,681 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14120,786,271 - 120,791,059 (+)NCBI
Celera4107,776,849 - 107,782,763 (+)NCBICelera
Cytogenetic Map4q34NCBI
Fam136a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542414,837,264 - 14,841,354 (+)NCBIChiLan1.0ChiLan1.0
FAM136A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.12A71,466,116 - 71,472,067 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A71,467,428 - 71,471,987 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v02A70,350,196 - 70,356,316 (-)NCBIMhudiblu_PPA_v0panPan3
FAM136A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11068,837,611 - 68,841,750 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Fam136a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_00493649114,451,858 - 14,456,710 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FAM136A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl372,190,972 - 72,197,360 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1372,190,918 - 72,196,789 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2375,462,137 - 75,467,935 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FAM136A
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11436,815,744 - 36,822,026 (+)NCBI
ChlSab1.1 Ensembl1436,815,711 - 36,822,023 (+)Ensembl
Fam136a
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247623,150,893 - 3,156,086 (+)NCBI

Position Markers
AW124904  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6D1UniSTS
Whitehead/MRC_RH15315.89UniSTS
UniSTS:493064  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm3884,652,008 - 4,652,607UniSTSGRCm38
MGSCv3784,652,008 - 4,652,607UniSTSGRCm37
Celera1515,011,301 - 15,011,892UniSTS
Celera84,846,208 - 4,846,807UniSTS
Cytogenetic Map6D1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301876Bits2_mbitterness sensitivity 2 (mouse)Not determined670425898104426034Mouse
10412195Efw_mepididymal fat weight (mouse)Not determined67554435694225955Mouse
10043864T2dm4sa_mtype 2 diabetes mellitus 4 in SMXA RI mice (mouse)Not determined683713869147052561Mouse
1301813Skl3_mskeletal size (tail length) 3 (mouse)Not determined670425898104426034Mouse
1300954Fcsa1_mfemoral cross-sectional area 1 (mouse)Not determined671981024105981170Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63866962592607450Mouse
13824985Alh1_mamplitude of lateral head displacement 1 (mouse)67800000097000000Mouse
1301571Arrd1_mage-related retinal degeneration 1 (mouse)Not determined67554435692607450Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)61117500000Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65854043392540433Mouse
10412208Cypr4_mcytokine production 4 (mouse)Not determined675716503109716697Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648720000125360000Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396656149Mouse
13506930Recrq9_mrecombination rate in male meiosis QTL 9 (mouse)673500000134700000Mouse
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396656149Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66348473897484905Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64531405987426034Mouse
1300650Bw18_mbody weight QTL 18 (mouse)Not determined666713869100714031Mouse
14697704Stsl4_mSalmonella typhimurium susceptibility locus 4 (mouse)67710000090000000Mouse
1302020Bbaa20_mB.burgdorferi-associated arthritis 20 (mouse)Not determined67132262193464093Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66005768094057799Mouse
15039373Adip28_madiposity 28 (mouse)65630821190308211Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65630821190308211Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652161713116155267Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46935985136423692Mouse
1301320Ots1_movarian teratoma susceptibility 1 (mouse)Not determined675447583104503555Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5437342788379171Mouse
1301034Egrm2_mearly growth rate (mouse)Not determined670425898104426034Mouse
1300869Stheal5_msoft tissue heal 5 (mouse)Not determined671575060105575178Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396656149Mouse
1300674Nidd3n_mnon-insulin-dependent diabetes mellitus 3 in NSY (mouse)Not determined67554435694225955Mouse
4141376Dbm1_mdiabetes modifier 1 (mouse)Not determined678629504121115387Mouse
14696731Pairq1_mP. aeruginosa infection resistance QTL 1 (mouse)681500000102200000Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139100000Mouse
10043901Pfat5_mpredicted fat percentage 5 (mouse)Not determined675607306109607450Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487426034Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65844758392447710Mouse
11251720Ewc4_methanol withdrawal and consumption 4 (mouse)684122513118122513Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396656149Mouse
1301521Pas1c_mpulmonary adenoma susceptibility 1c (mouse)Not determined671981024105981170Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648720000148450000Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645314059128835032Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648726556125356785Mouse
1357875Pfat2_mpredicted fat percentage 2 (mouse)Not determined676463949110464093Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:354
Count of miRNA genes:261
Interacting mature miRNAs:309
Transcripts:ENSMUST00000071492
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000071492   ⟹   ENSMUSP00000071426
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl686,365,646 - 86,370,058 (+)Ensembl
RefSeq Acc Id: ENSMUST00000203237
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl686,365,714 - 86,367,019 (+)Ensembl
RefSeq Acc Id: ENSMUST00000204893   ⟹   ENSMUSP00000145530
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl686,365,724 - 86,368,798 (+)Ensembl
RefSeq Acc Id: NM_001368363   ⟹   NP_001355292
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,342,453 - 86,347,040 (+)NCBI
GRCm38686,365,471 - 86,370,058 (+)NCBI
Sequence:
RefSeq Acc Id: NM_025591   ⟹   NP_079867
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39686,342,628 - 86,347,040 (+)NCBI
GRCm38686,365,646 - 86,370,058 (+)NCBI
MGSCv37686,315,677 - 86,320,052 (+)RGD
Celera688,303,323 - 88,307,699 (+)RGD
cM Map6 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_079867   ⟸   NM_025591
- Peptide Label: isoform 1
- UniProtKB: Q9CR98 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001355292   ⟸   NM_001368363
- Peptide Label: isoform 2
RefSeq Acc Id: ENSMUSP00000071426   ⟸   ENSMUST00000071492
RefSeq Acc Id: ENSMUSP00000145530   ⟸   ENSMUST00000204893

Promoters
RGD ID:6839281
Promoter ID:MM_KWN:46727
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_025591
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36686,315,251 - 86,315,872 (+)MPROMDB
RGD ID:6890272
Promoter ID:EPDNEW_M8587
Type:initiation region
Name:Fam136a_1
Description:Mus musculus family with sequence similarity 136, member A ,mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38686,365,724 - 86,365,784EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1913738 AgrOrtholog
Ensembl Genes ENSMUSG00000057497 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000071426 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000145530 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000071492 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000204893 UniProtKB/TrEMBL
InterPro DUF842_euk UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:66488 UniProtKB/Swiss-Prot
MGD MGI:1913738 ENTREZGENE
NCBI Gene 66488 ENTREZGENE
PANTHER PTHR21096 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF842 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fam136a PhenoGen
UniProt A0A0N4SWI4_MOUSE UniProtKB/TrEMBL
  F136A_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q91YY1 UniProtKB/Swiss-Prot