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Gene: ANO6 (anoctamin 6) Homo sapiens
Symbol: ANO6
Name: anoctamin 6
Description: Exhibits calcium activated cation channel activity; intracellular calcium activated chloride channel activity; and voltage-gated chloride channel activity. Involved in several processes, including bleb assembly; inorganic ion transmembrane transport; and positive regulation of blood coagulation. Localizes to the chloride channel complex; cytosol; and plasma membrane. Implicated in Scott syndrome; ankylosing spondylitis; and inflammatory bowel disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: anoctamin-6; BDPLT7; MGC104751; SCAN channel; SCTS; small-conductance calcium-activated nonselective cation channel; TMEM16F; transmembrane protein 16F
Mus musculus (house mouse) : Ano6 (anoctamin 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ano6 (anoctamin 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ano6 (anoctamin 6)
Pan paniscus (bonobo/pygmy chimpanzee) : ANO6 (anoctamin 6)
Canis lupus familiaris (dog) : ANO6 (anoctamin 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ano6 (anoctamin 6)
Sus scrofa (pig) : ANO6 (anoctamin 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl1245,215,987 - 45,440,404 (+)Ensembl
GRCh381245,216,033 - 45,440,404 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371245,609,770 - 45,834,187 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361243,896,170 - 44,112,399 (+)NCBINCBI36hg18NCBI36
Celera1244,413,462 - 44,637,876 (+)NCBI
Cytogenetic Map12q12NCBI
HuRef1242,638,190 - 42,862,629 (+)NCBIHuRef
CHM1_11245,574,740 - 45,799,189 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ANO6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312398
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-12-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.