Ifitm6 (interferon induced transmembrane protein 6) - Rat Genome Database

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Gene: Ifitm6 (interferon induced transmembrane protein 6) Mus musculus
Analyze
No known orthologs.
Symbol: Ifitm6
Name: interferon induced transmembrane protein 6
RGD ID: 1312326
MGI Page MGI
Description: Predicted to be involved in several processes, including defense response to other organism; negative regulation of viral process; and response to interferon-alpha. Predicted to localize to plasma membrane. Is expressed in embryo; lung; musculature; and spleen; INTERACTS WITH 1,2-dimethylhydrazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: A330075D07; Dspa2f; Fgls5; fra; fragilis 5; fragilis5; MGC129398; MGC129399
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397140,595,725 - 140,596,805 (-)NCBIGRCm39mm39
GRCm39 Ensembl7140,595,612 - 140,597,837 (-)Ensembl
GRCm387141,015,812 - 141,016,892 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7141,015,699 - 141,017,924 (-)EnsemblGRCm38mm10GRCm38
MGSCv377148,201,711 - 148,202,791 (-)NCBIGRCm37mm9NCBIm37
MGSCv367140,867,132 - 140,868,212 (-)NCBImm8
Celera7140,808,511 - 140,809,591 (-)NCBICelera
Cytogenetic Map7F5NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
1. MGD data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12659663   PMID:14610273   PMID:16141072   PMID:16141073   PMID:16602821   PMID:18505827  
PMID:20064371   PMID:21165565   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22363774   PMID:22537233  


Genomics

Position Markers
UniSTS:490529  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm387141,015,812 - 141,016,892UniSTSGRCm38
MGSCv377148,201,711 - 148,202,791UniSTSGRCm37
Celera7140,808,511 - 140,809,591UniSTS
Cytogenetic Map7F5UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753600000143600000Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773500000143600000Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7110108163144108163Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7110108163144108163Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7110108163144108163Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7111365511145365612Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7111365511145365612Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111564398145441459Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111564398145441459Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111564398145441459Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112950524145441459Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7113321003145441459Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7117032360145441459Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7119094158144844577Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119530844145441459Mouse
13207594Nigsq1_mneuroglucopenia-induced glucagon secretion QTL 1 (mouse)7127436844145441459Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127757504145441459Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127844414145441459Mouse
14746988Manh63_mmandible shape 63 (mouse)7128181700145441459Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:87
Count of miRNA genes:79
Interacting mature miRNAs:80
Transcripts:ENSMUST00000081924
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000081924   ⟹   ENSMUSP00000080594
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7141,015,706 - 141,016,908 (-)Ensembl
RefSeq Acc Id: ENSMUST00000209328   ⟹   ENSMUSP00000147357
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7141,015,699 - 141,017,924 (-)Ensembl
RefSeq Acc Id: ENSMUST00000211330   ⟹   ENSMUSP00000147821
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7141,015,701 - 141,017,558 (-)Ensembl
RefSeq Acc Id: NM_001033632   ⟹   NP_001028804
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397140,595,725 - 140,596,805 (-)NCBI
GRCm387141,015,812 - 141,016,892 (-)ENTREZGENE
MGSCv377148,201,711 - 148,202,791 (-)RGD
Celera7140,808,511 - 140,809,591 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_001028804 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI04339 (Get FASTA)   NCBI Sequence Viewer  
  AAI04340 (Get FASTA)   NCBI Sequence Viewer  
  AAP04423 (Get FASTA)   NCBI Sequence Viewer  
  EDL17978 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001028804   ⟸   NM_001033632
- UniProtKB: Q3SXF0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000147821   ⟸   ENSMUST00000211330
RefSeq Acc Id: ENSMUSP00000080594   ⟸   ENSMUST00000081924
RefSeq Acc Id: ENSMUSP00000147357   ⟸   ENSMUST00000209328

Promoters
RGD ID:8666055
Promoter ID:EPDNEW_M11059
Type:initiation region
Name:Ifitm6_1
Description:Mus musculus interferon induced transmembrane protein 6 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387141,016,908 - 141,016,968EPDNEW
RGD ID:6841319
Promoter ID:MM_KWN:53209
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:ENSMUST00000081924
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367148,202,626 - 148,203,297 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2686976 AgrOrtholog
Ensembl Genes ENSMUSG00000059108 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000080594 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000147357 UniProtKB/TrEMBL
  ENSMUSP00000147821 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000081924 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000209328 UniProtKB/TrEMBL
  ENSMUST00000211330 UniProtKB/TrEMBL
InterPro Interferon-induced_TM_protein UniProtKB/TrEMBL
KEGG Report mmu:213002 UniProtKB/TrEMBL
MGD MGI:2686976 ENTREZGENE
NCBI Gene 213002 ENTREZGENE
Pfam CD225 UniProtKB/TrEMBL
PhenoGen Ifitm6 PhenoGen
UniProt A0A1B0GS75_MOUSE UniProtKB/TrEMBL
  Q3SXF0 ENTREZGENE, UniProtKB/TrEMBL
  Q80WF2_MOUSE UniProtKB/TrEMBL