Selenon (selenoprotein N) - Rat Genome Database

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Gene: Selenon (selenoprotein N) Mus musculus
Analyze
Symbol: Selenon
Name: selenoprotein N
RGD ID: 1312091
MGI Page MGI
Description: Predicted to enable calcium ion binding activity and oxidoreductase activity. Involved in skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration. Acts upstream of or within several processes, including cellular response to caffeine; response to muscle activity involved in regulation of muscle adaptation; and skeletal muscle tissue development. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including diaphragm; embryo mesenchyme; limb; liver; and nervous system. Used to study rigid spine muscular dystrophy 1. Human ortholog(s) of this gene implicated in congenital fiber-type disproportion and rigid spine muscular dystrophy 1. Orthologous to human SELENON (selenoprotein N).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1110019I12Rik; AI414492; Se; selenoprotein N, 1; SelN; Sepn1
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394134,265,203 - 134,279,477 (-)NCBIGRCm39mm39
GRCm39 Ensembl4134,265,203 - 134,279,477 (-)Ensembl
GRCm384134,537,892 - 134,552,166 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,537,892 - 134,552,166 (-)EnsemblGRCm38mm10GRCm38
MGSCv374134,093,807 - 134,108,081 (-)NCBIGRCm37mm9NCBIm37
MGSCv364133,809,971 - 133,814,432 (-)NCBImm8
Celera4132,720,626 - 132,734,950 (-)NCBICelera
Cytogenetic Map4D3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15791204   PMID:16141072   PMID:16141073   PMID:16602821   PMID:19698141  
PMID:21131290   PMID:21267068   PMID:21677750   PMID:21858002   PMID:21873635   PMID:23325319   PMID:25452428   PMID:27645994   PMID:28106121   PMID:28378742   PMID:28836095   PMID:30391828  
PMID:30550785   PMID:32325033  


Genomics

Comparative Map Data
Selenon
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394134,265,203 - 134,279,477 (-)NCBIGRCm39mm39
GRCm39 Ensembl4134,265,203 - 134,279,477 (-)Ensembl
GRCm384134,537,892 - 134,552,166 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4134,537,892 - 134,552,166 (-)EnsemblGRCm38mm10GRCm38
MGSCv374134,093,807 - 134,108,081 (-)NCBIGRCm37mm9NCBIm37
MGSCv364133,809,971 - 133,814,432 (-)NCBImm8
Celera4132,720,626 - 132,734,950 (-)NCBICelera
Cytogenetic Map4D3NCBI
SELENON
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl125,800,193 - 25,818,221 (+)EnsemblGRCh38hg38GRCh38
GRCh38125,800,193 - 25,818,221 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37126,126,684 - 26,144,712 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36125,999,254 - 26,017,300 (+)NCBINCBI36hg18NCBI36
Celera124,522,754 - 24,540,804 (+)NCBI
Cytogenetic Map1p36.11NCBI
HuRef124,383,830 - 24,400,647 (+)NCBIHuRef
CHM1_1126,240,110 - 26,257,988 (+)NCBICHM1_1
Selenon
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25146,748,638 - 146,764,656 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl5152,750,284 - 152,762,165 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.05152,748,497 - 152,765,489 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.05156,534,095 - 156,553,701 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45153,295,598 - 153,308,305 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15153,305,727 - 153,317,685 (-)NCBI
Celera5145,163,547 - 145,177,184 (-)NCBICelera
Cytogenetic Map5q36NCBI
Selenon
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554525,296,035 - 5,309,102 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554525,295,716 - 5,311,113 (+)NCBIChiLan1.0ChiLan1.0
SELENON
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1126,126,602 - 26,144,249 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl126,127,125 - 26,141,745 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0125,058,907 - 25,076,817 (+)NCBIMhudiblu_PPA_v0panPan3
SELENON
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1274,134,448 - 74,149,585 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha270,709,452 - 70,725,728 (-)NCBI
ROS_Cfam_1.0274,696,398 - 74,712,673 (-)NCBI
UMICH_Zoey_3.1271,519,985 - 71,536,194 (-)NCBI
UNSW_CanFamBas_1.0272,526,878 - 72,542,967 (-)NCBI
UU_Cfam_GSD_1.0273,530,771 - 73,547,043 (-)NCBI
Selenon
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505844,556,838 - 44,571,856 (+)NCBI
SpeTri2.0NW_00493647410,381,646 - 10,396,638 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SELENON
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl683,246,934 - 83,262,746 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1683,246,934 - 83,262,748 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2676,814,410 - 76,821,459 (+)NCBISscrofa10.2Sscrofa10.2susScr3
SELENON
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120106,953,286 - 106,971,249 (-)NCBI
Vero_WHO_p1.0NW_0236660339,444,168 - 9,464,510 (+)NCBI
Selenon
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247649,892,161 - 9,905,984 (+)NCBI

Position Markers
AI414492  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm384134,538,098 - 134,538,195UniSTSGRCm38
MGSCv374134,094,013 - 134,094,110UniSTSGRCm37
Celera4132,720,832 - 132,720,929UniSTS
Cytogenetic Map4D3UniSTS
Whitehead/MRC_RH41776.04UniSTS
Sepn1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D3UniSTS
cM Map466.85UniSTS
Sepn1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D3UniSTS
Sepn1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4D3UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142082Psds2_mpsoriasis-like skin disease severity 2 (mouse)Not determined4133427367137890684Mouse
14746982Manh56_mmandible shape 56 (mouse)4118088606152088606Mouse
15039382Ltgq7_mliver triglyceride QTL 7 (mouse)4105812001139812001Mouse
15039377Bw45_mbody weight QTL 45 (mouse)4105812001139812001Mouse
10043985Stheal12_msoft tissue heal 12 (mouse)Not determined4121615338155615442Mouse
1301823Bmd7_mbone mineral density 7 (mouse)Not determined489063832151570093Mouse
12910808Pwbwq9_mpost-weaning body weight QTL 9 (mouse)4105978113141706527Mouse
10047132Albq19_malbuminuria QTL 19 (mouse)Not determined4112930596146930596Mouse
4142077Ignpq2_mIgA nephropathy QTL 2 (mouse)Not determined4133592276156508116Mouse
4142493Femwf13_mfemur work to failure 13 (mouse)Not determined116427367150427471Mouse
13208562Wght7_mweight 7 (mouse)491000000148000000Mouse
15039378Adip30_madiposity 30 (mouse)4105812001139812001Mouse
1300839Dyscalc2_mdystrophic cardiac calcinosis 2 (mouse)Not determined4111115258145115487Mouse
4142061Chlq16_mcirculating hormone level QTL 16 (mouse)Not determined4121615338155615442Mouse
4141001Tgq17_mtriglyceride QTL 17 (mouse)Not determined112629696146629696Mouse
4142139Adip12_madiposity 12 (mouse)Not determined4124893970156508116Mouse
4141093W3q17_mweight 3 weeks QTL 17 (mouse)Not determined89063832140740892Mouse
1301584Lrdg2_mlight induced retinal degeneration 2 (mouse)Not determined4129572018151570093Mouse
26884437Sklq13_mskull length QTL 13, 16 week (mouse)457700000155600000Mouse
1300803Sluc6_msusceptibility to lung cancer 6 (mouse)Not determined4120946694154946840Mouse
10412210Cypr6_mcytokine production 6 (mouse)Not determined4120890537154890684Mouse
15039385Mvlq3_mmacrovesicular liver lesion QTL 3 (mouse)4112288593146288593Mouse
26884445Sklq7_mskull length QTL 7, 10 week (mouse)468100000150800000Mouse
1301267Bcmd2_mB cell maturation defect 2 (mouse)Not determined4133427367150704994Mouse
1300743Skull6_mskull morphology 6 (mouse)Not determined4111115258145115487Mouse
10755531Lymph3_mlymphocyte differential 3 (mouse)4124826172156508116Mouse
10755522Hgb1_mhemoglobin 1 (mouse)4108583899142583899Mouse
1301793Tlsr3_mthymic lymphoma suppressor region 3 (mouse)Not determined4129572018137137225Mouse
1357800Tgq3_mtriglyceride QTL 3 (mouse)Not determined4107161300141161387Mouse
11533916Mts1_mmammary tumor susceptibility 1 (mouse)4125562755156508116Mouse
10755520Rbc1_mred blood cell count 1 (mouse)4108583899142583899Mouse
4141549W10q10_mweight 10 weeks QTL 10 (mouse)Not determined89063832140740892Mouse
4142481Gct1_mgranulosa cell tumorigenesis 1 (mouse)Not determined4128057656156508116Mouse
1300933Cdcs9_mcytokine deficiency colitis susceptibility 9 (mouse)Not determined4125504302156508116Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138615442Mouse
4141180Ssic1_msusceptibility to small intestinal cancer 1 (mouse)Not determined120946694154946840Mouse
10045620Heal22_mwound healing/regeneration 22 (mouse)Not determined4125504302156508116Mouse
1301982Pltiq1_mphospholipid transfer protein inducibility QTL 1 (mouse)Not determined4124893970156508116Mouse
1300621Tpnr1_mthermal pain response 1 (mouse)Not determined4125504302156508116Mouse
4141154Nba1_mNew Zealand Black autoimmunity 1 (mouse)Not determined131923413141151964Mouse
1357529Lvrq8_mliver weight QTL 8 (mouse)Not determined489063832140740892Mouse
1300874Gasa2_mgastritis type A susceptibility locus 2 (mouse)Not determined4132926037156508116Mouse
13503348Bntq18_mbone traits QTL 18 (mouse)4120890537154890684Mouse
25314312Syncl2_msynaptonemal complex length 2 (mouse)465800000146500000Mouse
4141623W6q13_mweight 6 weeks QTL 13 (mouse)Not determined89063832140740892Mouse
1301815Sles2_msystemic lupus erythmatosus suppressor 2 (mouse)Not determined495069342150592401Mouse
1300781Lith8_mlithogenic gene 8 (mouse)Not determined4107371164141371360Mouse
1302149Tlsr2_mthymic lymphoma suppressor region 2 (mouse)Not determined4124371164142504390Mouse
1300858Tafat_mtally ho associated mesenteric fat pad weight (mouse)Not determined4124893970156508116Mouse
12910813Pwbwq4_mpre-weaning body weight QTL 4 (mouse)4105978113141706527Mouse
1301382Arvm2_mautoimmune renal vasculitis 2 (mouse)Not determined4107897771141897963Mouse
1300663Start2_mstartle response 2 (mouse)Not determined4107371164141371360Mouse
1302102Bis1_mbeta-carboline-induced seizures 1 (mouse)Not determined4120137122154137225Mouse
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
12910797Pwgrq4_mpre-weaning growth rate QTL 4 (mouse)4105978113141706527Mouse
1301525Lmb1_mlupus in MRL and B6 F2 cross (mouse)Not determined4124371164150592401Mouse
10755521Hct1_mhematocrit 1 (mouse)4108583899142583899Mouse
1300809Ccrs2_mcorpus callosum hemisphere surface size 2 (mouse)Not determined4107371164141371360Mouse
1302078Sluc21_msusceptibility to lung cancer 21 (mouse)Not determined4117673830151673964Mouse
27226757Femd1_mfemur midshaft diameter 1, 5 week (mouse)4124100000144600000Mouse
12880433Fgf23lq1_mFGF23 serum level QTL 1 (mouse)4101300000135300000Mouse
1301964Bw8q2_mbody weight at 8 weeks QTL 2 (mouse)Not determined4120137122154137225Mouse
39128212Lwq21_mliver weight QTL 21 (mouse)489063832140740892Mouse
12910794Pwbwq8_mpost-weaning body weight QTL 8 (mouse)4105978113141706527Mouse
1301452Elsgp1_melevated serum gp70 1 (mouse)Not determined4121615338155615442Mouse
1300917Gasa1_mgastritis type A susceptibility locus 1 (mouse)Not determined4124161300142711450Mouse
4141065Shali2_msurvival time to hyperoxic acute lung injury 2 (mouse)Not determined124161300141845481Mouse
10043996Gct5_mgranulosa cell tumorigenesis 5 (mouse)Not determined4128057656156508116Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:927
Count of miRNA genes:502
Interacting mature miRNAs:603
Transcripts:ENSMUST00000060435, ENSMUST00000127585
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000060435   ⟹   ENSMUSP00000060026
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl4134,537,892 - 134,552,166 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127585
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl4134,539,579 - 134,541,022 (-)Ensembl
RefSeq Acc Id: NM_029100   ⟹   NP_083376
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm394134,265,203 - 134,279,477 (-)NCBI
GRCm384134,537,892 - 134,552,166 (-)ENTREZGENE
MGSCv374134,093,807 - 134,108,081 (-)RGD
Celera4132,720,626 - 132,734,950 (-)RGD
cM Map4 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_083376 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH22585 (Get FASTA)   NCBI Sequence Viewer  
  AAH43665 (Get FASTA)   NCBI Sequence Viewer  
  D3Z2R5 (Get FASTA)   NCBI Sequence Viewer  
  EDL30003 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_083376   ⟸   NM_029100
- Peptide Label: precursor
- UniProtKB: D3Z2R5 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000060026   ⟸   ENSMUST00000060435
Protein Domains
EF-hand

Promoters
RGD ID:6836367
Promoter ID:MM_KWN:40110
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain
Transcripts:OTTMUST00000026310
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364134,096,571 - 134,097,071 (-)MPROMDB
RGD ID:6836365
Promoter ID:MM_KWN:40111
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour
Transcripts:ENSMUST00000084231,   ENSMUST00000105865,   NM_029100
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv364134,107,679 - 134,108,179 (-)MPROMDB
RGD ID:6885034
Promoter ID:EPDNEW_M5968
Type:initiation region
Name:Selenon_1
Description:Mus musculus selenoprotein N , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm384134,552,166 - 134,552,226EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2151208 AgrOrtholog
Ensembl Genes ENSMUSG00000050989 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000060026 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000060435 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro EF_hand_dom UniProtKB/Swiss-Prot
KEGG Report mmu:74777 UniProtKB/Swiss-Prot
MGD MGI:2151208 ENTREZGENE
NCBI Gene 74777 ENTREZGENE
PhenoGen Selenon PhenoGen
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot
UniProt D3Z2R5 ENTREZGENE
  Q80UX9_MOUSE UniProtKB/TrEMBL
  Q8R246_MOUSE UniProtKB/TrEMBL
  SELN_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary D3Z5N3 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-10-25 Selenon  selenoprotein N  Sepn1  selenoprotein N, 1  Symbol and/or name change 5135510 APPROVED
2011-08-17 Sepn1  selenoprotein N, 1  Sepn1  selenoprotein N, 1  Symbol and/or name change 5135510 APPROVED