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Gene: FEM1B (fem-1 homolog B) Homo sapiens
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Symbol: FEM1B
Name: fem-1 homolog B
Description: This gene encodes an ankyrin repeat protein that belongs to the death receptor-associated family of proteins and plays a role in mediating apoptosis. The encoded protein is also thought to function in the replication stress-induced checkpoint signaling pathway via interaction with checkpoint kinase 1. [provided by RefSeq, Aug 2013]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: DKFZp451E0710; F1A-ALPHA; F1AA; fem-1 homolog b (C. elegans); FEM-1-like death receptor binding protein; fem-1-like death receptor-binding protein alpha; fem-1-like in apoptotic pathway protein alpha; FEM1-beta; FIAA; protein fem-1 homolog B
Orthologs:
Mus musculus (house mouse) : Fem1b (feminization 1 homolog b (C. elegans))  MGI  Alliance
Rattus norvegicus (Norway rat) : Fem1b (fem-1 homolog B)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fem1b (fem-1 homolog B)
Pan paniscus (bonobo/pygmy chimpanzee) : FEM1B (fem-1 homolog B)
Canis lupus familiaris (dog) : FEM1B (fem-1 homolog B)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fem1b (fem-1 homolog B)
Sus scrofa (pig) : FEM1B (fem-1 homolog B)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381568,277,803 - 68,295,865 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371568,570,141 - 68,583,640 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361566,357,195 - 66,370,694 (+)NCBINCBI36hg18NCBI36
Build 341566,357,194 - 66,370,693NCBI
Celera1545,455,064 - 45,468,563 (+)NCBI
Cytogenetic Map15q23NCBI
HuRef1545,400,895 - 45,414,396 (+)NCBIHuRef
CHM1_11568,688,084 - 68,706,153 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

Nucleotide Sequences
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Additional Information

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Nomenclature History
 
More on FEM1B
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312083
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2019-07-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.