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Gene: SENP6 (SUMO specific peptidase 6) Homo sapiens
Symbol: SENP6
Name: SUMO specific peptidase 6
Description: Exhibits SUMO-specific endopeptidase activity. Involved in protein desumoylation; regulation of kinetochore assembly; and regulation of spindle assembly. Localizes to cytosol and nucleoplasm.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2810017C20Rik; FLJ11355; FLJ11887; KIAA0389; KIAA0797; sentrin-specific protease 6; sentrin/SUMO-specific protease SENP6; SSP1; SUMO-1-specific protease 1; SUMO1/sentrin specific peptidase 6; SUMO1/sentrin specific protease 6; SUSP1
Mus musculus (house mouse) : Senp6 (SUMO/sentrin specific peptidase 6)  MGI  Alliance
Rattus norvegicus (Norway rat) : Senp6 (SUMO specific peptidase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Senp6 (SUMO specific peptidase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : SENP6 (SUMO specific peptidase 6)
Canis lupus familiaris (dog) : SENP6 (SUMO specific peptidase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Senp6 (SUMO specific peptidase 6)
Sus scrofa (pig) : SENP6 (SUMO specific peptidase 6)
Chlorocebus sabaeus (African green monkey) : SENP6 (SUMO specific peptidase 6)
Heterocephalus glaber (naked mole-rat) : Senp6 (SUMO specific peptidase 6)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl675,601,509 - 75,718,281 (+)EnsemblGRCh38hg38GRCh38
GRCh38675,601,509 - 75,718,281 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37676,311,596 - 76,427,997 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36676,368,342 - 76,484,714 (+)NCBINCBI36hg18NCBI36
Build 34676,368,960 - 76,482,901NCBI
Celera676,704,946 - 76,821,304 (+)NCBI
Cytogenetic Map6q14.1NCBI
HuRef673,510,247 - 73,626,304 (+)NCBIHuRef
CHM1_1676,477,481 - 76,594,220 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on SENP6
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1312076
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.