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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nudt18 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | RGD:1553634 | 6480464 | 1,2-Dimethylhydrazine results in increased expression of NUDT18 mRNA | CTD | PMID:22206623 | Nudt18 | Rat | 17beta-estradiol | increases expression | ISO | RGD:1553634 | 6480464 | Estradiol results in increased expression of NUDT18 mRNA | CTD | PMID:39298647 | Nudt18 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1605623 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NUDT18 mRNA | CTD | PMID:20106945 | Nudt18 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of NUDT18 mRNA | CTD | PMID:21215274|PMID:33387578 | Nudt18 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | RGD:1553634 | 6480464 | bisphenol S results in increased expression of NUDT18 mRNA | CTD | PMID:39298647 | Nudt18 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | RGD:1605623 | 6480464 | Decitabine affects the expression of NUDT18 mRNA | CTD | PMID:23300844 | Nudt18 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of NUDT18 mRNA | CTD | PMID:24780913 | Nudt18 | Rat | alpha-Zearalanol | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of NUDT18 mRNA | CTD | PMID:35163327 | Nudt18 | Rat | aristolochic acid A | decreases expression | ISO | RGD:1605623 | 6480464 | aristolochic acid I results in decreased expression of NUDT18 mRNA | CTD | PMID:33212167 | Nudt18 | Rat | arsane | multiple interactions | ISO | RGD:1605623 | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of NUDT18 more ... | CTD | PMID:32525701 | Nudt18 | Rat | arsenic atom | multiple interactions | ISO | RGD:1605623 | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of NUDT18 more ... | CTD | PMID:32525701 | Nudt18 | Rat | arsenous acid | increases expression | ISO | RGD:1605623 | 6480464 | Arsenic Trioxide results in increased expression of NUDT18 mRNA | CTD | PMID:15761015 | Nudt18 | Rat | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of NUDT18 mRNA | CTD | PMID:36841081 | Nudt18 | Rat | benzo[a]pyrene | multiple interactions | ISO | RGD:1553634 | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to NUDT18 promoter] | CTD | PMID:19654925 | Nudt18 | Rat | benzo[a]pyrene | increases expression | ISO | RGD:1553634 | 6480464 | Benzo(a)pyrene results in increased expression of NUDT18 mRNA | CTD | PMID:22228805 | Nudt18 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of NUDT18 mRNA | CTD | PMID:30816183|PMID:32528016 | Nudt18 | Rat | cadmium dichloride | increases expression | ISO | RGD:1605623 | 6480464 | Cadmium Chloride results in increased expression of NUDT18 mRNA | CTD | PMID:21457566 | Nudt18 | Rat | calcitriol | increases expression | ISO | RGD:1605623 | 6480464 | Calcitriol results in increased expression of NUDT18 mRNA | CTD | PMID:21592394 | Nudt18 | Rat | calcitriol | multiple interactions | ISO | RGD:1605623 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of NUDT18 mRNA | CTD | PMID:21592394 | Nudt18 | Rat | choline | multiple interactions | ISO | RGD:1553634 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Nudt18 | Rat | chromium(6+) | multiple interactions | ISO | RGD:1605623 | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression more ... | CTD | PMID:38479592 | Nudt18 | Rat | cisplatin | affects expression | ISO | RGD:1605623 | 6480464 | Cisplatin affects the expression of NUDT18 mRNA | CTD | PMID:23300844 | Nudt18 | Rat | cisplatin | multiple interactions | ISO | RGD:1605623 | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of NUDT18 mRNA | CTD | PMID:27392435 | Nudt18 | Rat | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of NUDT18 mRNA | CTD | PMID:24386269 | Nudt18 | Rat | cypermethrin | decreases expression | ISO | RGD:1553634 | 6480464 | cypermethrin results in decreased expression of NUDT18 mRNA | CTD | PMID:29020013 | Nudt18 | Rat | diarsenic trioxide | increases expression | ISO | RGD:1605623 | 6480464 | Arsenic Trioxide results in increased expression of NUDT18 mRNA | CTD | PMID:15761015 | Nudt18 | Rat | Dibutyl phosphate | affects expression | ISO | RGD:1605623 | 6480464 | di-n-butylphosphoric acid affects the expression of NUDT18 mRNA | CTD | PMID:37042841 | Nudt18 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of NUDT18 mRNA | CTD | PMID:24136188 | Nudt18 | Rat | folic acid | multiple interactions | ISO | RGD:1553634 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Nudt18 | Rat | GSK-J4 | decreases expression | ISO | RGD:1605623 | 6480464 | GSK-J4 results in decreased expression of NUDT18 mRNA | CTD | PMID:29301935 | Nudt18 | Rat | L-methionine | multiple interactions | ISO | RGD:1553634 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... | CTD | PMID:20938992 | Nudt18 | Rat | niclosamide | increases expression | ISO | RGD:1605623 | 6480464 | Niclosamide results in increased expression of NUDT18 mRNA | CTD | PMID:36318118 | Nudt18 | Rat | okadaic acid | decreases expression | ISO | RGD:1605623 | 6480464 | Okadaic Acid results in decreased expression of NUDT18 mRNA | CTD | PMID:38832940 | Nudt18 | Rat | paracetamol | affects expression | ISO | RGD:1553634 | 6480464 | Acetaminophen affects the expression of NUDT18 mRNA | CTD | PMID:17562736 | Nudt18 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of NUDT18 mRNA | CTD | PMID:33387578 | Nudt18 | Rat | perfluorooctanoic acid | multiple interactions | EXP | | 6480464 | [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of NUDT18 mRNA | CTD | PMID:35163327 | Nudt18 | Rat | phenobarbital | increases expression | ISO | RGD:1553634 | 6480464 | Phenobarbital results in increased expression of NUDT18 mRNA | CTD | PMID:19482888 | Nudt18 | Rat | phenobarbital | multiple interactions | ISO | RGD:1553634 | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of NUDT18 mRNA] | CTD | PMID:19482888 | Nudt18 | Rat | pirinixic acid | multiple interactions | ISO | RGD:1605623 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in more ... | CTD | PMID:19710929 | Nudt18 | Rat | pirinixic acid | increases expression | ISO | RGD:1553634 | 6480464 | pirinixic acid results in increased expression of NUDT18 mRNA | CTD | PMID:18301758|PMID:23811191 | Nudt18 | Rat | rotenone | decreases expression | ISO | RGD:1605623 | 6480464 | Rotenone results in decreased expression of NUDT18 mRNA | CTD | PMID:29955902 | Nudt18 | Rat | silicon dioxide | decreases expression | ISO | RGD:1605623 | 6480464 | Silicon Dioxide results in decreased expression of NUDT18 mRNA | CTD | PMID:25351596 | Nudt18 | Rat | sodium arsenate | multiple interactions | ISO | RGD:1605623 | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of NUDT18 more ... | CTD | PMID:32525701 | Nudt18 | Rat | sunitinib | increases expression | ISO | RGD:1605623 | 6480464 | Sunitinib results in increased expression of NUDT18 mRNA | CTD | PMID:31533062 | Nudt18 | Rat | testosterone | increases expression | ISO | RGD:1605623 | 6480464 | Testosterone results in increased expression of NUDT18 mRNA | CTD | PMID:21592394 | Nudt18 | Rat | testosterone | affects expression | ISO | RGD:1553634 | 6480464 | Testosterone affects the expression of NUDT18 mRNA | CTD | PMID:20403060 | Nudt18 | Rat | testosterone | multiple interactions | ISO | RGD:1605623 | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of NUDT18 mRNA | CTD | PMID:21592394 | Nudt18 | Rat | tetrachloromethane | affects expression | ISO | RGD:1553634 | 6480464 | Carbon Tetrachloride affects the expression of NUDT18 mRNA | CTD | PMID:17484886 | Nudt18 | Rat | tetrachloromethane | increases expression | ISO | RGD:1553634 | 6480464 | Carbon Tetrachloride results in increased expression of NUDT18 mRNA | CTD | PMID:31919559 | Nudt18 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of NUDT18 mRNA | CTD | PMID:34492290 | Nudt18 | Rat | titanium dioxide | decreases methylation | ISO | RGD:1553634 | 6480464 | titanium dioxide results in decreased methylation of NUDT18 promoter | CTD | PMID:35295148 | Nudt18 | Rat | titanium dioxide | decreases expression | ISO | RGD:1553634 | 6480464 | titanium dioxide results in decreased expression of NUDT18 mRNA | CTD | PMID:35295148 | Nudt18 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of NUDT18 mRNA | CTD | PMID:33387578 | Nudt18 | Rat | triclosan | increases expression | ISO | RGD:1605623 | 6480464 | Triclosan results in increased expression of NUDT18 mRNA | CTD | PMID:30510588 | Nudt18 | Rat | urethane | decreases expression | ISO | RGD:1605623 | 6480464 | Urethane results in decreased expression of NUDT18 mRNA | CTD | PMID:28818685 | Nudt18 | Rat | valproic acid | increases expression | ISO | RGD:1553634 | 6480464 | Valproic Acid results in increased expression of NUDT18 mRNA | CTD | PMID:19136453|PMID:21427059 | Nudt18 | Rat | valproic acid | increases methylation | ISO | RGD:1605623 | 6480464 | Valproic Acid results in increased methylation of NUDT18 gene | CTD | PMID:29154799 | Nudt18 | Rat | vitamin E | increases expression | ISO | RGD:1605623 | 6480464 | Vitamin E results in increased expression of NUDT18 mRNA | CTD | PMID:19244175 | |