Dnai7 (dynein axonemal intermediate chain 7) - Rat Genome Database
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Gene: Dnai7 (dynein axonemal intermediate chain 7) Rattus norvegicus
Analyze
Symbol: Dnai7
Name: dynein axonemal intermediate chain 7
RGD ID: 1311213
Description: Predicted to have beta-tubulin binding activity and microtubule binding activity. Predicted to colocalize with cytoplasmic microtubule. Orthologous to human CFAP94 (cilia and flagella associated protein 94); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cancer susceptibility 1; cancer susceptibility candidate 1; Casc1; Cfap94; cilia and flagella associated protein 94; dynein intermediate chain CFAP94, axonemal; Las1; LOC297720; lung adenoma susceptibility 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24178,143,499 - 178,179,871 (-)NCBI
Rnor_6.0 Ensembl4179,440,953 - 179,477,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04179,440,984 - 179,476,965 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04243,622,214 - 243,658,236 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44182,823,026 - 182,859,566 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14183,068,145 - 183,104,849 (-)NCBI
Celera4166,662,914 - 166,699,171 (-)NCBICelera
Cytogenetic Map4q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

Additional References at PubMed
PMID:8889548   PMID:12477932   PMID:14583591   PMID:17974961  


Genomics

Comparative Map Data
Dnai7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.24178,143,499 - 178,179,871 (-)NCBI
Rnor_6.0 Ensembl4179,440,953 - 179,477,070 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.04179,440,984 - 179,476,965 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04243,622,214 - 243,658,236 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44182,823,026 - 182,859,566 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14183,068,145 - 183,104,849 (-)NCBI
Celera4166,662,914 - 166,699,171 (-)NCBICelera
Cytogenetic Map4q44NCBI
DNAI7
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1225,108,289 - 25,195,162 (-)EnsemblGRCh38hg38GRCh38
GRCh381225,107,057 - 25,195,160 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371225,261,223 - 25,348,094 (-)NCBIGRCh37GRCh37hg19GRCh37
GRCh371225,261,223 - 25,348,096 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361225,152,490 - 25,239,361 (-)NCBINCBI36hg18NCBI36
Build 341225,152,489 - 25,239,361NCBI
Celera1230,408,204 - 30,495,049 (-)NCBI
Cytogenetic Map12p12.1NCBI
HuRef1225,031,916 - 25,118,815 (-)NCBIHuRef
CHM1_11225,226,353 - 25,313,241 (-)NCBICHM1_1
Casc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396145,120,556 - 145,156,866 (-)NCBIGRCm39mm39
GRCm386145,174,833 - 145,211,017 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6145,174,834 - 145,211,005 (-)EnsemblGRCm38mm10GRCm38
MGSCv376145,123,392 - 145,159,490 (-)NCBIGRCm37mm9NCBIm37
MGSCv366145,132,084 - 145,168,060 (-)NCBImm8
Celera6148,249,078 - 148,285,257 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map677.37NCBI
Dnai7
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541320,227,903 - 20,287,131 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541320,227,807 - 20,287,211 (-)NCBIChiLan1.0ChiLan1.0
DNAI7
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11263,733,801 - 63,819,991 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1263,733,785 - 63,819,991 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01261,117,886 - 61,204,888 (+)NCBIMhudiblu_PPA_v0panPan3
DNAI7
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2722,303,849 - 22,369,051 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12722,309,705 - 22,369,052 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dnai7
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365482,123,248 - 2,197,245 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAI7
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl548,555,669 - 48,677,416 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1548,555,637 - 48,651,370 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
DNAI7
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11124,871,767 - 24,953,586 (-)NCBI
ChlSab1.1 Ensembl1124,875,416 - 24,953,375 (-)Ensembl
Dnai7
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475213,855,328 - 13,932,210 (+)NCBI

Position Markers
RH132020  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.04179,441,018 - 179,441,209NCBIRnor6.0
Rnor_5.04243,622,248 - 243,622,439UniSTSRnor5.0
RGSC_v3.44182,823,060 - 182,823,251UniSTSRGSC3.4
Celera4166,662,948 - 166,663,139UniSTS
RH 3.4 Map41066.7UniSTS
Cytogenetic Map4q44UniSTS
RH133694  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.04179,462,571 - 179,462,761NCBIRnor6.0
Rnor_5.04243,643,875 - 243,644,065UniSTSRnor5.0
RGSC_v3.44182,845,204 - 182,845,394UniSTSRGSC3.4
Celera4166,684,953 - 166,685,143UniSTS
RH 3.4 Map41066.9UniSTS
Cytogenetic Map4q44UniSTS
AA943468  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.04179,477,326 - 179,477,447NCBIRnor6.0
Rnor_5.04243,658,630 - 243,658,751UniSTSRnor5.0
RGSC_v3.44182,859,960 - 182,860,081UniSTSRGSC3.4
Celera4166,699,565 - 166,699,686UniSTS
RH 3.4 Map41077.3UniSTS
Cytogenetic Map4q44UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4136351734180689124Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4136908430182878540Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)4137171018182171018Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157423126184226339Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)47850904182171018Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (VE) (CMO:0000132)4134917642179917642Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4145547014184226339Rat
6478720Alc23Alcohol consumption QTL 230.00509drinking behavior trait (VT:0001422)ethanol drink intake rate to body weight ratio (CMO:0001616)4155386197184226339Rat
6478728Anxrr36Anxiety related response QTL 360.01061locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478733Anxrr37Anxiety related response QTL 370.00095locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478737Anxrr38Anxiety related response QTL 380.00159locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4145547014184226339Rat
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4145547014184226339Rat
6478757Anxrr44Anxiety related response QTL 440.01087locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478782Anxrr52Anxiety related response QTL 520.02091locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478785Anxrr53Anxiety related response QTL 530.01397locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4155386197184226339Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4145547014184226339Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4145547014184226339Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4156855449184226339Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4146497452184226339Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:128
Count of miRNA genes:106
Interacting mature miRNAs:108
Transcripts:ENSRNOT00000030680
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 2 5 16 17 11
Low 1 43 49 35 14 35 8 11 58 35 24 8
Below cutoff 6 6 6

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001106627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107467 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107468 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107469 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107473 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107479 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC160907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF546873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BF562765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM388768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB695629 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CO386521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV108923 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV722478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000030680   ⟹   ENSRNOP00000035058
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4179,440,953 - 179,477,070 (-)Ensembl
RefSeq Acc Id: NM_001106627   ⟹   NP_001100097
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,179,792 (-)NCBI
Rnor_6.04179,440,984 - 179,476,932 (-)NCBI
Rnor_5.04243,622,214 - 243,658,236 (-)NCBI
RGSC_v3.44182,823,026 - 182,859,566 (-)RGD
Celera4166,662,914 - 166,699,171 (-)RGD
Sequence:
RefSeq Acc Id: XM_017592598   ⟹   XP_017448087
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04179,440,984 - 179,476,965 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017592599   ⟹   XP_017448088
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04179,442,400 - 179,476,962 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039107466   ⟹   XP_038963394
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107467   ⟹   XP_038963395
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107468   ⟹   XP_038963396
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,168,849 (-)NCBI
RefSeq Acc Id: XM_039107469   ⟹   XP_038963397
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,177,269 (-)NCBI
RefSeq Acc Id: XM_039107470   ⟹   XP_038963398
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,179,871 (-)NCBI
RefSeq Acc Id: XM_039107472   ⟹   XP_038963400
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,177,268 (-)NCBI
RefSeq Acc Id: XM_039107473   ⟹   XP_038963401
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107474   ⟹   XP_038963402
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107475   ⟹   XP_038963403
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,150,479 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107476   ⟹   XP_038963404
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,150,479 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107477   ⟹   XP_038963405
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,149,567 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107478   ⟹   XP_038963406
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,160,198 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107479   ⟹   XP_038963407
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,153,688 - 178,179,865 (-)NCBI
RefSeq Acc Id: XM_039107480   ⟹   XP_038963408
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.24178,143,499 - 178,155,489 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_001100097   ⟸   NM_001106627
- UniProtKB: B1H288 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448087   ⟸   XM_017592598
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017448088   ⟸   XM_017592599
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSRNOP00000035058   ⟸   ENSRNOT00000030680
RefSeq Acc Id: XP_038963398   ⟸   XM_039107470
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038963402   ⟸   XM_039107474
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038963401   ⟸   XM_039107473
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038963395   ⟸   XM_039107467
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038963394   ⟸   XM_039107466
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038963397   ⟸   XM_039107469
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038963400   ⟸   XM_039107472
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038963396   ⟸   XM_039107468
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038963408   ⟸   XM_039107480
- Peptide Label: isoform X12
RefSeq Acc Id: XP_038963405   ⟸   XM_039107477
- Peptide Label: isoform X9
RefSeq Acc Id: XP_038963404   ⟸   XM_039107476
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038963403   ⟸   XM_039107475
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038963407   ⟸   XM_039107479
- Peptide Label: isoform X11
RefSeq Acc Id: XP_038963406   ⟸   XM_039107478
- Peptide Label: isoform X10
Protein Domains
Casc1_N

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
Visual CSV TAB Printer
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
Visual CSV TAB Printer
Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
Visual CSV TAB Printer
Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311213 AgrOrtholog
Ensembl Genes ENSRNOG00000027630 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000035058 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030680 ENTREZGENE, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7455489 IMAGE-MGC_LOAD
InterPro Casc1 UniProtKB/TrEMBL
  Casc1_N UniProtKB/TrEMBL
KEGG Report rno:297720 UniProtKB/TrEMBL
MGC_CLONE MGC:188640 IMAGE-MGC_LOAD
NCBI Gene 297720 ENTREZGENE
PANTHER PTHR20929 UniProtKB/TrEMBL
Pfam Casc1_N UniProtKB/TrEMBL
PhenoGen Dnai7 PhenoGen
PRINTS CANCERSCCP1 UniProtKB/TrEMBL
UniProt B1H288 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-02-18 Dnai7  dynein axonemal intermediate chain 7  Cfap94  cilia and flagella associated protein 94  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2020-05-22 Cfap94  cilia and flagella associated protein 94  Casc1  cancer susceptibility 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2017-02-01 Casc1  cancer susceptibility 1  Casc1  cancer susceptibility candidate 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Casc1  cancer susceptibility candidate 1   Casc1_predicted  cancer susceptibility candidate 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Casc1_predicted  cancer susceptibility candidate 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED