Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of LYPLAL1 mRNA] | CTD | PMID:31150632 | (1->4)-beta-D-glucan | multiple interactions | ISO | Lyplal1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of LYPLAL1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | decreases expression | ISO | Lyplal1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of LYPLAL1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | Lyplal1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LYPLAL1 mRNA | CTD | PMID:17942748 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:31826744 | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Lyplal1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LYPLAL1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LYPLAL1 mRNA | CTD | PMID:33387578 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of LYPLAL1 mRNA | CTD | PMID:21346803 | 2-methylcholine | affects expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of LYPLAL1 mRNA | CTD | PMID:21179406 | 3,3',5,5'-tetrabromobisphenol A | increases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | tetrabromobisphenol A results in increased expression of LYPLAL1 protein | CTD | PMID:31675489 | 5-aza-2'-deoxycytidine | affects expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Decitabine affects the expression of LYPLAL1 mRNA | CTD | PMID:23300844 | aflatoxin B1 | decreases methylation | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of LYPLAL1 gene | CTD | PMID:27153756 | benzo[a]pyrene | increases expression | ISO | Lyplal1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of LYPLAL1 mRNA | CTD | PMID:22228805 | bisphenol A | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of LYPLAL1 mRNA and bisphenol A results in decreased expression of LYPLAL1 protein | CTD | PMID:22576693 and PMID:31675489 | bisphenol A | decreases expression | ISO | Lyplal1 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of LYPLAL1 mRNA | CTD | PMID:33221593 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LYPLAL1 mRNA | CTD | PMID:34947998 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of LYPLAL1 gene | CTD | PMID:28505145 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LYPLAL1 mRNA | CTD | PMID:25181051 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of LYPLAL1 mRNA | CTD | PMID:26496021 | bisphenol A | increases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of LYPLAL1 mRNA and bisphenol A results in increased expression of LYPLAL1 protein | CTD | PMID:25047013 and PMID:37567409 | bisphenol A | increases methylation | ISO | LYPLAL1 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of LYPLAL1 gene | CTD | PMID:22576693 and PMID:31601247 | Bisphenol B | increases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of LYPLAL1 protein | CTD | PMID:34186270 | CGP 52608 | multiple interactions | ISO | LYPLAL1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LYPLAL1 gene] | CTD | PMID:28238834 | choline | multiple interactions | ISO | Lyplal1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of LYPLAL1 gene | CTD | PMID:20938992 | cisplatin | affects expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Cisplatin affects the expression of LYPLAL1 mRNA | CTD | PMID:23300844 | cisplatin | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of LYPLAL1 mRNA | CTD | PMID:27392435 | cobalt dichloride | increases expression | ISO | Lyplal1 (Mus musculus) | 6480464 | cobaltous chloride results in increased expression of LYPLAL1 mRNA | CTD | PMID:21139344 | cobalt dichloride | decreases expression | EXP | | 6480464 | cobaltous chloride results in decreased expression of LYPLAL1 mRNA | CTD | PMID:24386269 | copper(II) sulfate | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of LYPLAL1 mRNA | CTD | PMID:19549813 | cyclosporin A | increases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of LYPLAL1 mRNA | CTD | PMID:20106945 | dibutyl phthalate | decreases expression | ISO | Lyplal1 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of LYPLAL1 mRNA | CTD | PMID:21266533 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of LYPLAL1 mRNA | CTD | PMID:21266533 | dicrotophos | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of LYPLAL1 mRNA | CTD | PMID:28302478 | epoxiconazole | increases expression | ISO | Lyplal1 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of LYPLAL1 mRNA | CTD | PMID:35436446 | ethanol | affects expression | ISO | Lyplal1 (Mus musculus) | 6480464 | Ethanol affects the expression of LYPLAL1 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | Lyplal1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of LYPLAL1 gene | CTD | PMID:20938992 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of LYPLAL1 mRNA | CTD | PMID:33387578 | glafenine | decreases expression | EXP | | 6480464 | Glafenine results in decreased expression of LYPLAL1 mRNA | CTD | PMID:24136188 | glycidyl methacrylate | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | glycidyl methacrylate results in decreased expression of LYPLAL1 protein | CTD | PMID:36641056 | hydrogen peroxide | multiple interactions | ISO | LYPLAL1 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LYPLAL1 protein | CTD | PMID:18951874 | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LYPLAL1 mRNA | CTD | PMID:22129741 | inulin | multiple interactions | ISO | Lyplal1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of LYPLAL1 mRNA | CTD | PMID:36331819 | L-methionine | multiple interactions | ISO | Lyplal1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased methylation of LYPLAL1 gene | CTD | PMID:20938992 | methylmercury chloride | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of LYPLAL1 mRNA | CTD | PMID:28001369 | N-acetyl-L-cysteine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LYPLAL1 mRNA | CTD | PMID:22129741 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LYPLAL1 mRNA | CTD | PMID:22129741 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of LYPLAL1 mRNA | CTD | PMID:24136188 | nickel atom | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of LYPLAL1 mRNA | CTD | PMID:24768652 and PMID:25583101 | p-toluidine | increases expression | EXP | | 6480464 | 4-toluidine results in increased expression of LYPLAL1 mRNA | CTD | PMID:27638505 | paracetamol | affects expression | ISO | Lyplal1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of LYPLAL1 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of LYPLAL1 mRNA | CTD | PMID:33387578 | paracetamol | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of LYPLAL1 mRNA | CTD | PMID:21420995 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Lyplal1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of LYPLAL1 mRNA more ... | CTD | PMID:36331819 | quercetin | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of LYPLAL1 mRNA | CTD | PMID:21632981 | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of LYPLAL1 mRNA | CTD | PMID:28374803 | testosterone | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Testosterone] results in increased expression of LYPLAL1 mRNA | CTD | PMID:26496021 | testosterone | decreases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of LYPLAL1 mRNA | CTD | PMID:33359661 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of LYPLAL1 mRNA] | CTD | PMID:31150632 | tetrachloromethane | decreases expression | ISO | Lyplal1 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of LYPLAL1 mRNA | CTD | PMID:31919559 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of LYPLAL1 mRNA | CTD | PMID:31150632 | thapsigargin | increases expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of LYPLAL1 mRNA | CTD | PMID:22378314 | theophylline | multiple interactions | ISO | LYPLAL1 (Homo sapiens) | 6480464 | [Hydrogen Peroxide co-treated with Theophylline] results in increased expression of LYPLAL1 protein | CTD | PMID:18951874 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of LYPLAL1 mRNA | CTD | PMID:34492290 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of LYPLAL1 gene | CTD | PMID:27618143 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of LYPLAL1 mRNA | CTD | PMID:33387578 | triptonide | increases expression | ISO | Lyplal1 (Mus musculus) | 6480464 | triptonide results in increased expression of LYPLAL1 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | ISO | Lyplal1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of LYPLAL1 mRNA | CTD | PMID:17292431 | valproic acid | affects expression | ISO | LYPLAL1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of LYPLAL1 mRNA | CTD | PMID:25979313 | vancomycin | increases expression | ISO | Lyplal1 (Mus musculus) | 6480464 | Vancomycin results in increased expression of LYPLAL1 mRNA | CTD | PMID:18930951 | |