Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of KLHL29 mRNA | CTD | PMID:28960355 | 17alpha-ethynylestradiol | multiple interactions | ISO | Klhl29 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KLHL29 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of KLHL29 mRNA | CTD | PMID:17942748 | 17beta-estradiol | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of KLHL29 mRNA | CTD | PMID:20660070 | 17beta-estradiol | increases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Estradiol results in increased expression of KLHL29 mRNA | CTD | PMID:31614463 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of KLHL29 mRNA | CTD | PMID:29581250 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Klhl29 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of KLHL29 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KLHL29 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KLHL29 mRNA | CTD | PMID:19933214 | 2-palmitoylglycerol | increases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | 2-palmitoylglycerol results in increased expression of KLHL29 mRNA | CTD | PMID:37199045 | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Klhl29 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of KLHL29 mRNA | CTD | PMID:20188158 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KLHL29 mRNA | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Klhl29 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of KLHL29 exon | CTD | PMID:33297965 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of KLHL29 gene | CTD | PMID:31601247 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of KLHL29 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of KLHL29 mRNA | CTD | PMID:24780913 | 7,12-dimethyltetraphene | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | 9 more ... | CTD | PMID:32553695 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of KLHL29 mRNA | CTD | PMID:31881176 | aconitine | increases expression | EXP | | 6480464 | Aconitine results in increased expression of KLHL29 protein | CTD | PMID:33236894 | aflatoxin B1 | increases methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of KLHL29 exon | CTD | PMID:30157460 | aflatoxin B1 | affects methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the methylation of KLHL29 intron | CTD | PMID:30157460 | Aflatoxin B2 alpha | increases methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of KLHL29 exon more ... | CTD | PMID:30157460 | aristolochic acid A | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of KLHL29 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | Arsenic affects the methylation of KLHL29 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | Arsenic affects the methylation of KLHL29 gene | CTD | PMID:25304211 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of KLHL29 gene | CTD | PMID:28931070 | benzo[a]pyrene | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of KLHL29 mRNA | CTD | PMID:20106945 | benzo[a]pyrene | affects methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of KLHL29 3' UTR more ... | CTD | PMID:27901495 and PMID:30157460 | benzo[a]pyrene | affects methylation | ISO | Klhl29 (Mus musculus) | 6480464 | Benzo(a)pyrene affects the methylation of KLHL29 intron | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of KLHL29 mRNA | CTD | PMID:21569818 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | benzo[e]pyrene | increases methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of KLHL29 exon and benzo(e)pyrene results in increased methylation of KLHL29 intron | CTD | PMID:30157460 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of KLHL29 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | decreases methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of KLHL29 gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of KLHL29 mRNA | CTD | PMID:34947998 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of KLHL29 gene | CTD | PMID:28505145 | bisphenol A | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KLHL29 mRNA | CTD | PMID:28628672 | carbon nanotube | affects expression | ISO | Klhl29 (Mus musculus) | 6480464 | Nanotubes and Carbon affects the expression of KLHL29 mRNA | CTD | PMID:25554681 | carbon nanotube | increases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of KLHL29 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to KLHL29 gene] | CTD | PMID:28238834 | chloroprene | increases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Chloroprene results in increased expression of KLHL29 mRNA | CTD | PMID:23125180 | chlorpyrifos | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of KLHL29 mRNA | CTD | PMID:37019170 | chrysene | increases expression | ISO | Klhl29 (Mus musculus) | 6480464 | chrysene results in increased expression of KLHL29 mRNA | CTD | PMID:26377693 | cisplatin | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of KLHL29 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of KLHL29 mRNA | CTD | PMID:27392435 | cyclosporin A | increases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of KLHL29 mRNA | CTD | PMID:20106945 | dexamethasone | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KLHL29 mRNA | CTD | PMID:28628672 | dorsomorphin | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of KLHL29 mRNA and Doxorubicin results in decreased expression of KLHL29 protein | CTD | PMID:28962528 | doxorubicin | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of KLHL29 mRNA | CTD | PMID:29803840 | doxorubicin | affects methylation | EXP | | 6480464 | Doxorubicin affects the methylation of KLHL29 gene | CTD | PMID:28962528 | ethanol | multiple interactions | ISO | Klhl29 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of KLHL29 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of KLHL29 mRNA | CTD | PMID:23649840 | folic acid | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of KLHL29 mRNA | CTD | PMID:25629700 | formaldehyde | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of KLHL29 mRNA | CTD | PMID:23649840 | furan | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | furan results in decreased expression of KLHL29 mRNA | CTD | PMID:24183702 | genistein | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Genistein results in decreased expression of KLHL29 mRNA | CTD | PMID:22553218 | glyphosate | increases methylation | EXP | | 6480464 | Glyphosate results in increased methylation of KLHL29 gene | CTD | PMID:31011160 | indometacin | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of KLHL29 mRNA | CTD | PMID:28628672 | methapyrilene | increases methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of KLHL29 exon and Methapyrilene results in increased methylation of KLHL29 intron | CTD | PMID:30157460 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of KLHL29 gene | CTD | PMID:35440735 | methyl methanesulfonate | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of KLHL29 mRNA | CTD | PMID:23649840 | p-chloromercuribenzoic acid | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in decreased expression of KLHL29 mRNA | CTD | PMID:26272509 | p-chloromercuribenzoic acid | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of KLHL29 mRNA | CTD | PMID:27188386 | paracetamol | increases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of KLHL29 mRNA | CTD | PMID:29067470 | perfluorooctanoic acid | increases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of KLHL29 mRNA | CTD | PMID:36326898 | phenobarbital | affects expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Phenobarbital affects the expression of KLHL29 mRNA | CTD | PMID:19159669 | potassium dichromate | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of KLHL29 mRNA | CTD | PMID:23608068 | progesterone | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [Estradiol co-treated with Progesterone] results in increased expression of KLHL29 mRNA | CTD | PMID:20660070 | SB 431542 | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | silver atom | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Silver results in decreased expression of KLHL29 mRNA | CTD | PMID:27131904 | silver(0) | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | Silver results in decreased expression of KLHL29 mRNA | CTD | PMID:27131904 | sodium arsenite | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of KLHL29 mRNA | CTD | PMID:34032870 | sulforaphane | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | sulforaphane results in decreased expression of KLHL29 mRNA | CTD | PMID:30529165 | sulforaphane | decreases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of KLHL29 mRNA | CTD | PMID:31838189 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of KLHL29 mRNA | CTD | PMID:34492290 | trichostatin A | increases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of KLHL29 mRNA | CTD | PMID:24935251 | triclosan | increases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Triclosan results in increased expression of KLHL29 mRNA | CTD | PMID:30510588 | trimellitic anhydride | decreases expression | ISO | Klhl29 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of KLHL29 mRNA | CTD | PMID:19042947 | tris(2-butoxyethyl) phosphate | affects expression | ISO | KLHL29 (Homo sapiens) | 6480464 | tris(2-butoxyethyl) phosphate affects the expression of KLHL29 mRNA | CTD | PMID:29024780 | valproic acid | affects expression | ISO | Klhl29 (Mus musculus) | 6480464 | Valproic Acid affects the expression of KLHL29 mRNA | CTD | PMID:17963808 | valproic acid | increases expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of KLHL29 mRNA | CTD | PMID:19101580 more ... | valproic acid | multiple interactions | ISO | KLHL29 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of KLHL29 mRNA | CTD | PMID:27188386 | valproic acid | increases methylation | ISO | KLHL29 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of KLHL29 gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | KLHL29 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of KLHL29 mRNA | CTD | PMID:25979313 | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of KLHL29 mRNA | CTD | PMID:23034163 | |