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Gene: Dux4 (double homeobox 4) Rattus norvegicus
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Symbol: Dux4
Name: double homeobox 4
Description: Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Predicted to be involved in several processes, including negative regulation of G0 to G1 transition; negative regulation of cell population proliferation; and positive regulation of transcription by RNA polymerase II. Predicted to localize to the Golgi apparatus; cytosol; and nucleus. Orthologous to several human genes including DUX4L2 (double homeobox 4 like 2 (pseudogene)); DUX4L4 (double homeobox 4 like 4 (pseudogene)); and DUX4L9 (double homeobox 4 like 9 (pseudogene)); INTERACTS WITH (RS)-amphetamine; butanal (ortholog); tebuconazole (ortholog).
Type: protein-coding
RefSeq Status: MODEL
Also known as: double homeobox B-like; double homeobox B-like 1; double homeobox protein 4C-like; Duxbl; Duxbl1; LOC306226; RGD1311053; similar to double homeobox protein
Orthologs:
Homo sapiens (human) : DUX4 (double homeobox 4)  HGNC  Alliance
Mus musculus (house mouse) : Dux (double homeobox)  MGI
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0163,754,968 - 3,766,532 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl163,754,968 - 3,765,917 (-)Ensembl
Rnor_5.0163,720,950 - 3,732,462 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4161,600,636 - 1,606,916 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1161,597,461 - 1,606,066 (+)NCBI
Celera161,534,238 - 1,545,775 (+)NCBICelera
Cytogenetic Map16p16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants (Rnor 6.0)
Damaging Variants

Additional Information

External Database Links
Nomenclature History
 
More on Dux4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1311053
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-08-20
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.