Sec22b (SEC22 homolog B, vesicle trafficking protein) - Rat Genome Database

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Gene: Sec22b (SEC22 homolog B, vesicle trafficking protein) Rattus norvegicus
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Symbol: Sec22b
Name: SEC22 homolog B, vesicle trafficking protein
RGD ID: 1309988
Description: Enables syntaxin binding activity. Predicted to be involved in Golgi vesicle transport; negative regulation of autophagosome assembly; and positive regulation of protein catabolic process. Predicted to act upstream of or within vesicle-mediated transport. Located in COPI-coated vesicle. Part of SNARE complex. Is active in synaptic vesicle. Orthologous to human SEC22B (SEC22 homolog B, vesicle trafficking protein); PARTICIPATES IN phagocytosis pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 3,4-methylenedioxymethamphetamine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ER-Golgi SNARE of 24 kDa; ERS-24; ERS24; LOC310710; MGC112717; SEC22 vesicle trafficking protein homolog B; SEC22 vesicle trafficking protein homolog B (S. cerevisiae); SEC22 vesicle trafficking protein-like 1 (S. cerevisiae); SEC22 vesicle-trafficking protein homolog B; SEC22 vesicle-trafficking protein-like 1; Sec22l1; vesicle-trafficking protein SEC22b
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82188,188,783 - 188,209,565 (+)NCBIGRCr8
mRatBN7.22185,500,029 - 185,520,811 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2185,500,004 - 185,522,026 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2193,147,655 - 193,169,369 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02190,956,128 - 190,977,833 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02185,780,242 - 185,801,956 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02200,076,079 - 200,096,861 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2200,076,054 - 200,098,076 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02219,551,836 - 219,572,618 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42192,743,195 - 192,763,977 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12192,705,948 - 192,726,731 (+)NCBI
Celera2177,991,104 - 178,011,886 (+)NCBICelera
Cytogenetic Map2q34NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics. Steegmaier M, etal., Mol Biol Cell. 2000 Aug;11(8):2719-31.
8. Molecular anatomy of a trafficking organelle. Takamori S, etal., Cell. 2006 Nov 17;127(4):831-46.
9. Members of a mammalian SNARE complex interact in the endoplasmic reticulum in vivo and are found in COPI vesicles. Verrier SE, etal., Eur J Cell Biol. 2008 Nov;87(11):863-78. doi: 10.1016/j.ejcb.2008.07.003. Epub 2008 Oct 1.
Additional References at PubMed
PMID:9094723   PMID:11035026   PMID:11042173   PMID:12477932   PMID:14742712   PMID:15308636   PMID:15489334   PMID:17499046   PMID:18504258   PMID:21242315   PMID:21700703   PMID:24625528  
PMID:33186631   PMID:33450132  


Genomics

Comparative Map Data
Sec22b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82188,188,783 - 188,209,565 (+)NCBIGRCr8
mRatBN7.22185,500,029 - 185,520,811 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2185,500,004 - 185,522,026 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2193,147,655 - 193,169,369 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02190,956,128 - 190,977,833 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02185,780,242 - 185,801,956 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02200,076,079 - 200,096,861 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2200,076,054 - 200,098,076 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02219,551,836 - 219,572,618 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42192,743,195 - 192,763,977 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12192,705,948 - 192,726,731 (+)NCBI
Celera2177,991,104 - 178,011,886 (+)NCBICelera
Cytogenetic Map2q34NCBI
SEC22B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381120,150,898 - 120,176,520 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1120,150,898 - 120,176,520 (-)EnsemblGRCh38hg38GRCh38
GRCh371120,693,460 - 120,697,156 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361143,807,764 - 143,828,279 (+)NCBINCBI36Build 36hg18NCBI36
Build 341142,585,471 - 142,606,033NCBI
Cytogenetic Map1p12NCBI
CHM1_11120,814,032 - 120,834,611 (-)NCBICHM1_1
T2T-CHM13v2.01120,164,165 - 120,189,787 (-)NCBIT2T-CHM13v2.0
Sec22b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39397,808,543 - 97,829,634 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl397,808,506 - 97,830,592 (+)EnsemblGRCm39 Ensembl
GRCm38397,901,227 - 97,922,318 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl397,901,190 - 97,923,276 (+)EnsemblGRCm38mm10GRCm38
MGSCv37397,705,150 - 97,726,241 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36397,986,632 - 98,007,723 (+)NCBIMGSCv36mm8
Celera399,300,229 - 99,321,320 (+)NCBICelera
Cytogenetic Map3F2.2NCBI
cM Map342.35NCBI
Sec22b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555681,559,452 - 1,587,782 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555681,559,519 - 1,587,782 (+)NCBIChiLan1.0ChiLan1.0
SEC22B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21112,798,509 - 112,819,801 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11112,400,981 - 112,422,292 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0182,383,313 - 82,404,612 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
SEC22B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11757,094,038 - 57,115,891 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1757,053,218 - 57,115,886 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1756,732,928 - 56,754,271 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01757,974,306 - 57,996,180 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11756,998,099 - 57,020,005 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01757,034,820 - 57,056,678 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01757,682,634 - 57,704,489 (-)NCBIUU_Cfam_GSD_1.0
Sec22b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244050582,791,486 - 2,844,458 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936872294,066 - 313,293 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936872294,116 - 313,893 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SEC22B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4100,880,937 - 100,905,993 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14100,880,843 - 100,900,942 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24110,848,659 - 110,868,687 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SEC22B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12013,602,852 - 13,624,483 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2013,602,870 - 13,622,650 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603816,237,498 - 16,259,142 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sec22b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477215,803,369 - 15,833,968 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477215,800,793 - 15,833,453 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sec22b
82 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:222
Count of miRNA genes:139
Interacting mature miRNAs:178
Transcripts:ENSRNOT00000025327
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2161699179222436696Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2114837527211674221Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2168358098223265385Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2136445150202447032Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2122609194206936711Rat
70162Bp63Blood pressure QTL 635.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2114837675212549332Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2143657411190602963Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2157142209202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
61469Bp16Blood pressure QTL 165.64arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)2169745596214745596Rat
70175BpQTLCluster3Blood pressure QTL cluster 34.128arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)2135552573202446871Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2157142078211086598Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2184114274202447032Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2114837527185876470Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2136916935189599348Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2157142078192625452Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150540301202447032Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2136916935213594495Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
2300189Bmd48Bone mineral density QTL 485.80.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)2179335906224335906Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2157142078226277316Rat
631501Bp101Blood pressure QTL 1012.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150341684202446871Rat
2307174Activ3Activity QTL 34.830.000058locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)2168594495213594495Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2141194931223265385Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2141596551202447032Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2141194931223265385Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150341585189039377Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2112456140212696837Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2143157029210020885Rat
7488929Bp366Blood pressure QTL 3660.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2184974550193094998Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2133914684202447032Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2144599348189599348Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2112456140212696837Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561221167075Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2150540301202447032Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2147798556192798556Rat
61417Cia10Collagen induced arthritis QTL 103.4joint integrity trait (VT:0010548)experimental arthritis severity measurement (CMO:0001459)2179946951224946951Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2162765032207765032Rat
1598838Bp290Blood pressure QTL 2901.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166539266211539266Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2160564068205564068Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
2293084Iddm26Insulin dependent diabetes mellitus QTL 262.9blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2174930955213594495Rat

Markers in Region
RH127609  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22185,520,490 - 185,520,677 (+)MAPPERmRatBN7.2
Rnor_6.02200,096,541 - 200,096,727NCBIRnor6.0
Rnor_5.02219,572,298 - 219,572,484UniSTSRnor5.0
RGSC_v3.42192,763,657 - 192,763,843UniSTSRGSC3.4
Celera2178,011,566 - 178,011,752UniSTS
RH 3.4 Map21251.8UniSTS
Cytogenetic Map2q34UniSTS
RH129053  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22185,521,828 - 185,522,014 (+)MAPPERmRatBN7.2
Rnor_6.02200,097,879 - 200,098,064NCBIRnor6.0
Rnor_5.02219,573,636 - 219,573,821UniSTSRnor5.0
RGSC_v3.42192,764,995 - 192,765,180UniSTSRGSC3.4
Celera2178,012,904 - 178,013,089UniSTS
RH 3.4 Map21253.3UniSTS
Cytogenetic Map2q34UniSTS
RH142986  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22185,501,419 - 185,501,537 (+)MAPPERmRatBN7.2
Rnor_6.02200,077,470 - 200,077,587NCBIRnor6.0
Rnor_5.02219,553,227 - 219,553,344UniSTSRnor5.0
RGSC_v3.42192,744,586 - 192,744,703UniSTSRGSC3.4
Celera2177,992,495 - 177,992,612UniSTS
RH 3.4 Map21255.3UniSTS
Cytogenetic Map2q34UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000025327   ⟹   ENSRNOP00000025327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2185,500,004 - 185,522,026 (+)Ensembl
Rnor_6.0 Ensembl2200,076,054 - 200,098,076 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093465
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl2200,082,201 - 200,090,038 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099730   ⟹   ENSRNOP00000087902
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2185,500,050 - 185,520,807 (+)Ensembl
RefSeq Acc Id: NM_001025686   ⟹   NP_001020857
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82188,188,783 - 188,209,565 (+)NCBI
mRatBN7.22185,500,029 - 185,520,811 (+)NCBI
Rnor_6.02200,076,079 - 200,096,861 (+)NCBI
Rnor_5.02219,551,836 - 219,572,618 (+)NCBI
RGSC_v3.42192,743,195 - 192,763,977 (+)RGD
Celera2177,991,104 - 178,011,886 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001020857 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH98725 (Get FASTA)   NCBI Sequence Viewer  
  EDL85575 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025327.4
  ENSRNOP00000087902.1
  ENSRNOP00055046673
  ENSRNOP00060018048
  ENSRNOP00065042649
GenBank Protein Q4KM74 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001020857   ⟸   NM_001025686
- UniProtKB: Q4KM74 (UniProtKB/Swiss-Prot),   A6K3C5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025327   ⟸   ENSRNOT00000025327
Ensembl Acc Id: ENSRNOP00000087902   ⟸   ENSRNOT00000099730
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q4KM74-F1-model_v2 AlphaFold Q4KM74 1-215 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691599
Promoter ID:EPDNEW_R2124
Type:initiation region
Name:Sec22b_1
Description:SEC22 homolog B, vesicle trafficking protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02200,076,066 - 200,076,126EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309988 AgrOrtholog
BioCyc Gene G2FUF-51926 BioCyc
Ensembl Genes ENSRNOG00000018673 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055032718 UniProtKB/Swiss-Prot
  ENSRNOG00060013383 UniProtKB/Swiss-Prot
  ENSRNOG00065029991 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000025327.9 UniProtKB/Swiss-Prot
  ENSRNOT00000099730.1 UniProtKB/TrEMBL
  ENSRNOT00055056567 UniProtKB/Swiss-Prot
  ENSRNOT00060022805 UniProtKB/Swiss-Prot
  ENSRNOT00065051816 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Longin domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7378284 IMAGE-MGC_LOAD
InterPro Longin-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Longin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sec22 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synaptobrevin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V_SNARE_CC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:310710 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:112717 IMAGE-MGC_LOAD
NCBI Gene 310710 ENTREZGENE
PANTHER PTHR45837 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  VESICLE-TRAFFICKING PROTEIN SEC22B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Longin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Synaptobrevin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sec22b PhenoGen
PRINTS SYNAPTOBREVN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LONGIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  V_SNARE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018673 RatGTEx
  ENSRNOG00055032718 RatGTEx
  ENSRNOG00060013383 RatGTEx
  ENSRNOG00065029991 RatGTEx
SMART Longin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SNARE fusion complex UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF64356 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I6A6S7_RAT UniProtKB/TrEMBL
  A6K3C5 ENTREZGENE, UniProtKB/TrEMBL
  Q4KM74 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-20 Sec22b  SEC22 homolog B, vesicle trafficking protein  Sec22b  SEC22 vesicle trafficking protein homolog B (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Sec22b  SEC22 vesicle trafficking protein homolog B (S. cerevisiae)  Sec22l1  SEC22 vesicle trafficking protein-like 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Sec22l1  SEC22 vesicle trafficking protein-like 1 (S. cerevisiae)  Sec22l1_predicted  SEC22 vesicle trafficking protein-like 1 (S. cerevisiae) (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Sec22l1_predicted  SEC22 vesicle trafficking protein-like 1 (S. cerevisiae) (predicted)      Symbol and Name status set to approved 70820 APPROVED