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Gene: Tsen2 (tRNA splicing endonuclease subunit 2) Rattus norvegicus
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Symbol: Tsen2
Name: tRNA splicing endonuclease subunit 2
Description: Predicted to have tRNA-intron endonuclease activity. Predicted to be involved in tRNA-type intron splice site recognition and cleavage. Predicted to localize to the centrosome; cytosol; and nucleus. Human ortholog(s) of this gene implicated in pontocerebellar hypoplasia type 2B. Orthologous to human TSEN2 (tRNA splicing endonuclease subunit 2); PARTICIPATES IN tRNA maturation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 4-amino-2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC312649; RGD1309946; similar to hypothetical protein MGC2776; tRNA splicing endonuclease 2 homolog (S. cerevisiae); tRNA splicing endonuclease 2 homolog (SEN2, S. cerevisiae); tRNA-intron endonuclease Sen2; tRNA-intron nuclease 2; tRNA-splicing endonuclease subunit Sen2; TSEN2 tRNA splicing endonuclease subunit
Orthologs:
Homo sapiens (human) : TSEN2 (tRNA splicing endonuclease subunit 2)  HGNC  Alliance
Mus musculus (house mouse) : Tsen2 (tRNA splicing endonuclease subunit 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tsen2 (tRNA splicing endonuclease subunit 2)
Pan paniscus (bonobo/pygmy chimpanzee) : TSEN2 (tRNA splicing endonuclease subunit 2)
Canis lupus familiaris (dog) : TSEN2 (tRNA splicing endonuclease subunit 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tsen2 (tRNA splicing endonuclease subunit 2)
Sus scrofa (pig) : TSEN2 (tRNA splicing endonuclease subunit 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04147,455,506 - 147,490,869 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.04210,742,791 - 210,778,839 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44151,672,953 - 151,708,835 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14151,917,793 - 151,953,680 (+)NCBI
Celera4137,494,385 - 137,528,921 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Tsen2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309946
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-23
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.