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Gene: Top3b (DNA topoisomerase III beta) Rattus norvegicus
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Symbol: Top3b
Name: DNA topoisomerase III beta
Description: Predicted to have DNA topoisomerase activity. Predicted to be involved in DNA topological change and chromosome segregation. Predicted to localize to the condensed chromosome and nucleus. Orthologous to human TOP3B (DNA topoisomerase III beta); PARTICIPATES IN homologous recombination pathway of double-strand break repair; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; acrylamide.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: DNA topoisomerase 3-beta-1; LOC287930; topoisomerase (DNA) III beta
Orthologs:
Homo sapiens (human) : TOP3B (DNA topoisomerase III beta)  HGNC  Alliance
Mus musculus (house mouse) : Top3b (topoisomerase (DNA) III beta)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Top3b (DNA topoisomerase III beta)
Pan paniscus (bonobo/pygmy chimpanzee) : TOP3B (DNA topoisomerase III beta)
Canis lupus familiaris (dog) : TOP3B (DNA topoisomerase III beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Top3b (DNA topoisomerase III beta)
Sus scrofa (pig) : TOP3B (DNA topoisomerase III beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01188,346,305 - 88,374,896 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01191,401,389 - 91,429,964 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41186,116,936 - 86,145,314 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11186,157,538 - 86,185,850 (-)NCBI
Celera1182,851,647 - 82,880,025 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome
Promoters

Strain Variation

Strain Sequence Variants (Rnor 5.0)

Additional Information

External Database Links
Nomenclature History
 
More on Top3b
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1309468
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2019-04-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.