Msh4 (mutS homolog 4) - Rat Genome Database

Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Gene: Msh4 (mutS homolog 4) Rattus norvegicus
Analyze
Symbol: Msh4
Name: mutS homolog 4
RGD ID: 1309190
Description: Predicted to enable double-stranded DNA binding activity. Predicted to be involved in reciprocal meiotic recombination. Predicted to act upstream of or within several processes, including homologous chromosome pairing at meiosis; ovarian follicle development; and spermatogenesis. Predicted to be located in recombination nodule and synaptonemal complex. Predicted to be part of MutSalpha complex. Predicted to be active in nucleus. Orthologous to human MSH4 (mutS homolog 4); INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; bisphenol A; 17beta-estradiol (ortholog).
Type: protein-coding
RefSeq Status: INFERRED
Previously known as: LOC295541; mutS homolog 4 (E. coli); mutS protein homolog 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22242,785,392 - 242,844,609 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2242,792,661 - 242,843,487 (-)Ensembl
Rnor_6.02260,057,708 - 260,108,897 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2260,057,855 - 260,108,897 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02278,716,760 - 278,773,060 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42251,801,090 - 251,851,133 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12251,815,109 - 251,866,523 (-)NCBI
Celera2234,728,057 - 234,775,779 (-)NCBICelera
Cytogenetic Map2q45NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10809667   PMID:15467367   PMID:16260499   PMID:18316482   PMID:22164254   PMID:23555294   PMID:27760146  


Genomics

Comparative Map Data
Msh4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22242,785,392 - 242,844,609 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl2242,792,661 - 242,843,487 (-)Ensembl
Rnor_6.02260,057,708 - 260,108,897 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2260,057,855 - 260,108,897 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02278,716,760 - 278,773,060 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42251,801,090 - 251,851,133 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12251,815,109 - 251,866,523 (-)NCBI
Celera2234,728,057 - 234,775,779 (-)NCBICelera
Cytogenetic Map2q45NCBI
MSH4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38175,796,882 - 75,913,242 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl175,796,882 - 75,913,242 (+)EnsemblGRCh38hg38GRCh38
GRCh37176,262,567 - 76,378,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36176,035,218 - 76,151,511 (+)NCBINCBI36hg18NCBI36
Build 34175,974,650 - 76,090,944NCBI
Celera174,502,536 - 74,619,128 (+)NCBI
Cytogenetic Map1p31.1NCBI
HuRef174,392,386 - 74,509,072 (+)NCBIHuRef
CHM1_1176,377,843 - 76,494,293 (+)NCBICHM1_1
T2T-CHM13v2.0175,633,544 - 75,751,219 (+)NCBI
Msh4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393153,562,778 - 153,611,775 (-)NCBIGRCm39mm39
GRCm39 Ensembl3153,562,786 - 153,611,775 (-)Ensembl
GRCm383153,857,141 - 153,906,138 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3153,857,149 - 153,906,138 (-)EnsemblGRCm38mm10GRCm38
MGSCv373153,520,111 - 153,569,102 (-)NCBIGRCm37mm9NCBIm37
MGSCv363153,794,533 - 153,843,524 (-)NCBImm8
Celera3160,320,812 - 160,369,813 (-)NCBICelera
Cytogenetic Map3H3NCBI
Msh4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542317,093,573 - 17,154,910 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542317,093,573 - 17,154,910 (-)NCBIChiLan1.0ChiLan1.0
MSH4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1176,983,852 - 77,099,896 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl176,983,852 - 77,099,896 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0175,011,947 - 75,130,036 (+)NCBIMhudiblu_PPA_v0panPan3
MSH4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1670,745,777 - 70,822,507 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl670,746,634 - 70,823,004 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha673,406,292 - 73,487,796 (-)NCBI
ROS_Cfam_1.0671,334,444 - 71,416,137 (-)NCBI
UMICH_Zoey_3.1670,834,791 - 70,912,065 (-)NCBI
UNSW_CanFamBas_1.0670,780,166 - 70,856,995 (-)NCBI
UU_Cfam_GSD_1.0671,269,093 - 71,350,596 (-)NCBI
Msh4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505887,311,249 - 87,388,210 (+)NCBI
SpeTri2.0NW_0049365712,827,283 - 2,898,562 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MSH4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6137,410,691 - 137,534,233 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16137,410,820 - 137,524,459 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26127,382,425 - 127,496,604 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MSH4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12057,283,723 - 57,397,871 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2057,284,575 - 57,396,797 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603360,112,696 - 60,228,261 (+)NCBIVero_WHO_p1.0
Msh4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474221,098,101 - 21,167,398 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_00462474221,098,102 - 21,167,472 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
RH127932  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22242,844,856 - 242,845,073 (+)MAPPERmRatBN7.2
Rnor_6.02260,110,408 - 260,110,624NCBIRnor6.0
Rnor_5.02278,774,475 - 278,774,691UniSTSRnor5.0
RGSC_v3.42251,852,644 - 251,852,860UniSTSRGSC3.4
Celera2234,777,290 - 234,777,506UniSTS
RH 3.4 Map21629.8UniSTS
Cytogenetic Map2q45UniSTS


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat
631563Hcuc3Hepatic copper content QTL 33.87hepatic copper amount (VT:0003065)liver copper weight to liver dry weight ratio (CMO:0001512)2229059610249053267Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:14
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000014106
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3
Low 22 20
Below cutoff 8 10 2 18 2 3 3 36 22 14 10 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000014106   ⟹   ENSRNOP00000014106
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2242,792,661 - 242,843,487 (-)Ensembl
Rnor_6.0 Ensembl2260,057,855 - 260,108,897 (-)Ensembl
RefSeq Acc Id: NM_001106477   ⟹   NP_001099947
RefSeq Status: INFERRED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22242,792,991 - 242,843,346 (-)NCBI
Rnor_6.02260,057,855 - 260,108,897 (-)NCBI
Rnor_5.02278,716,760 - 278,773,060 (-)NCBI
RGSC_v3.42251,801,090 - 251,851,133 (-)RGD
Celera2234,728,057 - 234,775,779 (-)RGD
Sequence:
RefSeq Acc Id: XM_039102112   ⟹   XP_038958040
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22242,785,392 - 242,844,609 (-)NCBI
RefSeq Acc Id: XM_039102113   ⟹   XP_038958041
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22242,792,772 - 242,826,500 (-)NCBI
RefSeq Acc Id: XM_039102114   ⟹   XP_038958042
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.22242,792,772 - 242,816,557 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001099947 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958040 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958041 (Get FASTA)   NCBI Sequence Viewer  
  XP_038958042 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL82522 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001099947   ⟸   NM_001106477
- UniProtKB: F1M9U4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014106   ⟸   ENSRNOT00000014106
RefSeq Acc Id: XP_038958040   ⟸   XM_039102112
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038958041   ⟸   XM_039102113
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038958042   ⟸   XM_039102114
- Peptide Label: isoform X3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M9U4-F1-model_v2 AlphaFold F1M9U4 1-911 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (mRatBN7.2)
ACI/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
ACI/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN-Lx/CubMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/NHsdMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BN/SsN (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BUF/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH2/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
BXH3/CubMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
DA/OlaHsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/DuCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
F344/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FHH/EurMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE16/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
FXLE18/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
GK/FarMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB10/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB2/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB20/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB31/IpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
HXB4/IpcvMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LE/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEW/Crl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF10A/StmMcwi (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF11/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1A/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF1C/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF2B/Stm (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF3/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LEXF4/Stm (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LH/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LL/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
LN/MavRrrcAek (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Kwitek
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
M520/NRrrcMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MR/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
MWF/Hsd (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
PVG/Seac (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Japan
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHR/OlalpcvMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SHRSP/A3NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SR/JrHsd (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Envigo
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
SS/JrHsdMcwi (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: MCW
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WAG/RijCrl (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WKY/NCrl (2019)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: Charles River
Description: Dr. Mindy Dwinell - Hybrid rat diversity program
WN/N (2020)
Visual CSV TAB Printer
Platform: GSPMC-Illumina-NovaSeq6000
Secondary Analysis: BWA_mem_v.0.7.17,_GATK_v.4.1.3.0
Breeder: NIH
Description: Dr. Mindy Dwinell - Hybrid rat diversity program

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309190 AgrOrtholog
BioCyc Gene G2FUF-50777 BioCyc
Ensembl Genes ENSRNOG00000010431 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000014106 ENTREZGENE
  ENSRNOP00000014106.5 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014106 ENTREZGENE
  ENSRNOT00000014106.6 UniProtKB/TrEMBL
Gene3D-CATH 3.30.420.110 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro DNA_mismatch_repair_MutS UniProtKB/TrEMBL
  DNA_mismatch_repair_MutS_C UniProtKB/TrEMBL
  DNA_mismatch_repair_MutS_clamp UniProtKB/TrEMBL
  DNA_mismatch_repair_MutS_core UniProtKB/TrEMBL
  DNA_mismatch_repair_MutS_sf UniProtKB/TrEMBL
  DNA_mmatch_repair_MutS_con_dom UniProtKB/TrEMBL
  MutS_con_dom_sf UniProtKB/TrEMBL
  MutS_family UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
KEGG Report rno:295541 UniProtKB/TrEMBL
NCBI Gene 295541 ENTREZGENE
PANTHER PTHR11361 UniProtKB/TrEMBL
Pfam MutS_II UniProtKB/TrEMBL
  MutS_III UniProtKB/TrEMBL
  MutS_IV UniProtKB/TrEMBL
  MutS_V UniProtKB/TrEMBL
PhenoGen Msh4 PhenoGen
PIRSF MSH2 UniProtKB/TrEMBL
PROSITE DNA_MISMATCH_REPAIR_2 UniProtKB/TrEMBL
SMART MUTSac UniProtKB/TrEMBL
  MUTSd UniProtKB/TrEMBL
Superfamily-SCOP DNA_mismatch_repair_MutS_connt UniProtKB/TrEMBL
  DNA_repair_MutS_domIII UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt F1M9U4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-19 Msh4  mutS homolog 4  Msh4  mutS homolog 4 (E. coli)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Msh4  mutS homolog 4 (E. coli)   Msh4_predicted  mutS homolog 4 (E. coli) (predicted)  'predicted' is removed 2292626 APPROVED
2008-01-09 Msh4_predicted  mutS homolog 4 (E. coli) (predicted)  LOC688159  similar to mutS homolog 4  Data Merged 1643240 APPROVED
2006-11-20 LOC688159  similar to mutS homolog 4      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Msh4_predicted  mutS homolog 4 (E. coli) (predicted)      Symbol and Name status set to approved 70820 APPROVED