C2h4orf17 (similar to human chromosome 4 open reading frame 17) - Rat Genome Database

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Gene: C2h4orf17 (similar to human chromosome 4 open reading frame 17) Rattus norvegicus
Analyze
Symbol: C2h4orf17
Name: similar to human chromosome 4 open reading frame 17
RGD ID: 1309170
Description: Orthologous to human C4orf17 (chromosome 4 open reading frame 17); INTERACTS WITH bisphenol A; gentamycin; trichloroethene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: hypothetical protein LOC362047; LOC362047; RGD1309170; similar to hypothetical protein DKFZp434G072; uncharacterized protein C4orf17 homolog; uncharacterized protein LOC362047
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,367,215 - 229,395,674 (-)NCBIGRCr8
mRatBN7.22226,693,808 - 226,722,277 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,693,809 - 226,722,289 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2234,433,164 - 234,461,491 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,332,905 - 232,361,232 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02227,197,581 - 227,225,908 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,447,167 - 243,475,625 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,447,168 - 243,475,639 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02261,988,210 - 262,016,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,694,437 - 235,714,972 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12235,681,099 - 235,709,603 (-)NCBI
Celera2218,849,996 - 218,870,833 (-)NCBICelera
Cytogenetic Map2q43-q44NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
C2h4orf17
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,367,215 - 229,395,674 (-)NCBIGRCr8
mRatBN7.22226,693,808 - 226,722,277 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,693,809 - 226,722,289 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2234,433,164 - 234,461,491 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,332,905 - 232,361,232 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02227,197,581 - 227,225,908 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,447,167 - 243,475,625 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,447,168 - 243,475,639 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02261,988,210 - 262,016,658 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,694,437 - 235,714,972 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12235,681,099 - 235,709,603 (-)NCBI
Celera2218,849,996 - 218,870,833 (-)NCBICelera
Cytogenetic Map2q43-q44NCBI
C4orf17
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38499,511,021 - 99,542,303 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl499,511,012 - 99,542,303 (+)EnsemblGRCh38hg38GRCh38
GRCh374100,432,178 - 100,463,460 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364100,651,223 - 100,682,483 (+)NCBINCBI36Build 36hg18NCBI36
Build 344100,789,377 - 100,820,636NCBI
Celera497,729,579 - 97,760,871 (+)NCBICelera
Cytogenetic Map4q23NCBI
HuRef496,170,245 - 96,201,546 (+)NCBIHuRef
CHM1_14100,408,619 - 100,439,932 (+)NCBICHM1_1
T2T-CHM13v2.04102,825,795 - 102,857,071 (+)NCBIT2T-CHM13v2.0
4930579F01Rik
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393137,869,839 - 137,899,592 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3137,869,839 - 137,945,424 (-)EnsemblGRCm39 Ensembl
GRCm383138,164,078 - 138,193,831 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3138,164,078 - 138,239,663 (-)EnsemblGRCm38mm10GRCm38
MGSCv373137,827,099 - 137,849,677 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363138,101,466 - 138,131,212 (-)NCBIMGSCv36mm8
Celera3144,576,250 - 144,592,847 (-)NCBICelera
Cytogenetic Map3G3NCBI
cM Map364.1NCBI
CUNH4orf17
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554968,046,391 - 8,065,418 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554968,047,756 - 8,068,982 (-)NCBIChiLan1.0ChiLan1.0
C3H4orf17
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,592,897 - 97,630,624 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1497,876,607 - 97,908,201 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0491,934,411 - 91,966,190 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,595,856 - 102,627,084 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,595,784 - 102,627,084 (+)Ensemblpanpan1.1panPan2
C32H4orf17
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13221,511,695 - 21,561,074 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3221,511,737 - 21,544,222 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3220,335,319 - 20,389,684 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03221,727,897 - 21,782,271 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3221,727,938 - 21,765,382 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13221,704,737 - 21,759,010 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03221,492,379 - 21,546,709 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03218,322,585 - 18,378,122 (-)NCBIUU_Cfam_GSD_1.0
CUNH4orf17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530120,075,695 - 20,098,784 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365203,419,290 - 3,436,597 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365203,419,290 - 3,436,597 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C8H4orf17
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8120,918,344 - 120,990,184 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18120,918,456 - 121,266,698 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28130,134,152 - 130,253,039 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CUNH4orf17
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1747,643,565 - 47,685,065 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl747,649,429 - 47,683,190 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603726,113,200 - 26,150,049 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
CUNH4orf17
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248307,532,981 - 7,557,423 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C2h4orf17
201 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:11
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000045169
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301408Kidm36Kidney mass QTL 360.002kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2190613715226808892Rat
1598813Memor9Memory QTL 92.7exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2199341726234244620Rat
8693697Alc36Alcohol consumption QTL 3620.592drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2217139753236660713Rat
1298075Scl17Serum cholesterol level QTL 173.4blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)2211744537249053267Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
2298479Eau5Experimental allergic uveoretinitis QTL 50.0021uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)2202446871237938339Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1300126Bp175Blood pressure QTL 1753.46arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2214226044247136170Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)218960362228801039Rat
7207484Bss108Bone structure and strength QTL 1085.3femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)2211744537249053267Rat
2313073Bmd75Bone mineral density QTL 754.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)2215377404237938339Rat
7411555Bw132Body weight QTL 1320.001body mass (VT:0001259)body weight gain (CMO:0000420)2223389739249053267Rat
738013Alc15Alcohol consumption QTL 154.10.00022consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)2184165752229165752Rat
61398Bp50Blood pressure QTL 504.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2189599258234599258Rat
7207482Bss107Bone structure and strength QTL 1077femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)2211744537249053267Rat
2317752Glom23Glomerulus QTL 233.6urine protein amount (VT:0005160)urine protein level (CMO:0000591)2193452645245889826Rat
1549836Bss2Bone structure and strength QTL 27.5femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)2211744537249053267Rat
2317885Alcrsp28Alcohol response QTL 282.10.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2212828222249053267Rat
1581499Esta2Estrogen-induced thymic atrophy QTL 2thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2189599258226936289Rat
1331767Hrtrt12Heart rate QTL 123.373heart pumping trait (VT:2000009)heart rate (CMO:0000002)2218414747240841241Rat
9589044Scfw1Subcutaneous fat weight QTL 15.80.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)2182171407227171407Rat
8694435Bw166Body weight QTL 16614.080.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)2182171407227171407Rat
2293833Kiddil8Kidney dilation QTL 82.9kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
8694383Bw158Body weight QTL 1587.690.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)2182171407227171407Rat
1598835Anxrr18Anxiety related response QTL 182.98body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)2200990457245990457Rat
7207490Bss111Bone structure and strength QTL 1116.4femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)2211744537249053267Rat
8693622Alc26Alcohol consumption QTL 262.40.667drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)2221136523241305619Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2164073756227146641Rat
8694194Abfw1Abdominal fat weight QTL 111.70.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)2182171407227171407Rat
61366Iddm3Insulin dependent diabetes mellitus QTL 34.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2189599258234599258Rat
9587428Epfw6Epididymal fat weight QTL 67.470.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)2223389739249053267Rat
2293844Kiddil7Kidney dilation QTL 73.5kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)2219753301247136170Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2149559561249053267Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 10 10 63 40 39 12 23 12 6 94 53 45 13 47 27

Sequence


Ensembl Acc Id: ENSRNOT00000045169   ⟹   ENSRNOP00000045614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2226,693,809 - 226,714,354 (-)Ensembl
Rnor_6.0 Ensembl2243,447,168 - 243,467,703 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000089222   ⟹   ENSRNOP00000071865
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2226,693,809 - 226,722,289 (-)Ensembl
Rnor_6.0 Ensembl2243,447,183 - 243,475,639 (-)Ensembl
RefSeq Acc Id: NM_001134579   ⟹   NP_001128051
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,367,215 - 229,395,659 (-)NCBI
mRatBN7.22226,693,808 - 226,722,258 (-)NCBI
Rnor_6.02243,447,168 - 243,467,703 (-)NCBI
Rnor_5.02261,988,210 - 262,016,658 (-)NCBI
RGSC_v3.42235,694,437 - 235,714,972 (-)RGD
Celera2218,849,996 - 218,870,833 (-)RGD
Sequence:
RefSeq Acc Id: XM_063282226   ⟹   XP_063138296
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82229,367,268 - 229,395,674 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001128051 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138296 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL82310 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000045614.3
  ENSRNOP00000071865.1
RefSeq Acc Id: NP_001128051   ⟸   NM_001134579
- UniProtKB: A0A0G2K1J3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071865   ⟸   ENSRNOT00000089222
Ensembl Acc Id: ENSRNOP00000045614   ⟸   ENSRNOT00000045169
RefSeq Acc Id: XP_063138296   ⟸   XM_063282226
- Peptide Label: isoform X1
- UniProtKB: A6HW24 (UniProtKB/TrEMBL),   D4AAS0 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K1J3-F1-model_v2 AlphaFold A0A0G2K1J3 1-334 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691800
Promoter ID:EPDNEW_R2308
Type:initiation region
Name:RGD1309170_1
Description:similar to hypothetical protein DKFZp434G072
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.02243,475,610 - 243,475,670EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309170 AgrOrtholog
BioCyc Gene G2FUF-51080 BioCyc
Ensembl Genes ENSRNOG00000024623 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045169.5 UniProtKB/TrEMBL
  ENSRNOT00000089222.2 UniProtKB/TrEMBL
InterPro TBATA-like UniProtKB/TrEMBL
KEGG Report rno:362047 UniProtKB/TrEMBL
NCBI Gene 362047 ENTREZGENE
PANTHER PTHR33772 UniProtKB/TrEMBL
  RIKEN CDNA 4930579F01 GENE UniProtKB/TrEMBL
Pfam SPATIAL UniProtKB/TrEMBL
PhenoGen C2h4orf17 PhenoGen
RatGTEx ENSRNOG00000024623 RatGTEx
UniProt A0A0G2K1J3 ENTREZGENE, UniProtKB/TrEMBL
  A6HW24 ENTREZGENE, UniProtKB/TrEMBL
  D4AAS0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 C2h4orf17  similar to human chromosome 4 open reading frame 17  RGD1309170  similar to hypothetical protein DKFZp434G072  Symbol and Name Changed 1299863 APPROVED
2008-04-30 RGD1309170  similar to hypothetical protein DKFZp434G072   RGD1309170_predicted  similar to hypothetical protein DKFZp434G072 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1309170_predicted  similar to hypothetical protein DKFZp434G072 (predicted)  LOC362047_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC362047_predicted  similar to hypothetical protein DKFZp434G072 (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL