Slain1 (SLAIN motif family, member 1)

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Gene: Slain1 (SLAIN motif family, member 1) Rattus norvegicus

Analyze

Symbol:

Slain1

Name:

SLAIN motif family, member 1

RGD ID:

1308626

Description:

Orthologous to human SLAIN1 (SLAIN motif family member 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

hypothetical protein LOC361087; LOC361087; RGD1308626; similar to 9630044O09Rik protein; SLAIN motif-containing protein 1; uncharacterized protein LOC361087

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	80,482,818 - 80,542,461 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	80,482,367 - 80,542,350 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	84,462,499 - 84,522,163 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	15	85,585,541 - 85,645,202 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	15	82,513,170 - 82,572,840 (+)	NCBI	Rnor_WKY
Rnor_6.0	15	87,862,832 - 87,906,472 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	87,886,783 - 87,906,474 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	91,357,889 - 91,401,695 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	87,720,662 - 87,770,016 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	87,736,441 - 87,785,803 (+)	NCBI
Celera	15	79,632,758 - 79,675,830 (+)	NCBI		Celera
Cytogenetic Map	15	q21	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

chromosome 13q14 deletion syndrome (ISO)

genetic disease (ISO)

neuronal ceroid lipofuscinosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3',4,4',5-Pentachlorobiphenyl (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,4-dibromophenyl 2,4,5-tribromophenyl ether (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

6-propyl-2-thiouracil (EXP)

aflatoxin B1 (ISO)

aflatoxin M1 (ISO)

all-trans-retinoic acid (ISO)

amphetamine (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

bisphenol A (EXP)

bisphenol F (EXP)

buta-1,3-diene (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

copper atom (ISO)

copper(0) (ISO)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

epoxiconazole (ISO)

fenvalerate (EXP)

folic acid (ISO)

formaldehyde (ISO)

gallic acid (ISO)

methyl methanesulfonate (ISO)

Muraglitazar (EXP)

paracetamol (EXP,ISO)

phenylmercury acetate (ISO)

potassium chromate (ISO)

progesterone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sunitinib (ISO)

temozolomide (ISO)

Tesaglitazar (EXP)

thioacetamide (EXP)

trichostatin A (ISO)

troglitazone (EXP)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Genomics

Comparative Map Data

Slain1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	80,482,818 - 80,542,461 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	80,482,367 - 80,542,350 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	84,462,499 - 84,522,163 (+)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	15	85,585,541 - 85,645,202 (+)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	15	82,513,170 - 82,572,840 (+)	NCBI	Rnor_WKY
Rnor_6.0	15	87,862,832 - 87,906,472 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	87,886,783 - 87,906,474 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	91,357,889 - 91,401,695 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	87,720,662 - 87,770,016 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	87,736,441 - 87,785,803 (+)	NCBI
Celera	15	79,632,758 - 79,675,830 (+)	NCBI		Celera
Cytogenetic Map	15	q21	NCBI

SLAIN1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	13	77,697,687 - 77,764,229 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	13	77,697,687 - 77,764,242 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	13	78,271,822 - 78,338,364 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	13	77,170,471 - 77,236,378 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	13	59,170,471 - 59,236,367 (+)	NCBI		Celera
Cytogenetic Map	13	q22.3	NCBI
HuRef	13	58,969,702 - 59,037,136 (+)	NCBI		HuRef
CHM1_1	13	78,239,942 - 78,305,763 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	13	76,922,360 - 76,989,219 (+)	NCBI		T2T-CHM13v2.0

Slain1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	103,887,664 - 103,942,343 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	103,887,664 - 103,942,343 (+)	Ensembl		GRCm39 Ensembl
GRCm38	14	103,650,228 - 103,704,907 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	103,650,228 - 103,704,907 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	104,049,460 - 104,104,019 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	102,535,922 - 102,590,481 (+)	NCBI		MGSCv36	mm8
Celera	14	102,277,925 - 102,332,181 (+)	NCBI		Celera
Cytogenetic Map	14	E2.3	NCBI

Slain1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955404	29,535,923 - 29,595,141 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955404	29,537,497 - 29,594,617 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLAIN1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	13	77,956,027 - 78,021,872 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
Mhudiblu_PPA_v0	13	58,914,327 - 58,981,193 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

SLAIN1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	22	31,199,494 - 31,258,920 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	22	31,199,533 - 31,258,021 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	22	31,059,969 - 31,119,380 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	22	31,518,440 - 31,577,868 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	22	31,518,472 - 31,577,762 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	22	31,178,235 - 31,237,893 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	22	31,216,534 - 31,275,927 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	22	31,290,054 - 31,349,399 (+)	NCBI		UU_Cfam_GSD_1.0

Slain1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	128,198,023 - 128,254,849 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936511	3,614,303 - 3,671,847 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936511	3,615,251 - 3,671,429 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLAIN1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	11	49,807,994 - 49,886,822 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	11	49,807,976 - 49,886,829 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	11	54,498,235 - 54,504,073 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLAIN1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	3	56,774,381 - 56,840,862 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	3	56,774,157 - 56,839,851 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666046	12,994,744 - 13,061,499 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slain1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624751	22,608,843 - 22,674,805 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624751	22,609,259 - 22,674,805 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Slain1
353 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	136
Count of miRNA genes:	87
Interacting mature miRNAs:	120
Transcripts:	ENSRNOT00000065710
Prediction methods:	Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	40631268	98288169	Rat
1576315	Schws6	Schwannoma susceptibility QTL 6		0.0069	nervous system integrity trait (VT:0010566)	post-insult time of death (CMO:0002005)	15	53806152	98806152	Rat
61477	Aia4	Adjuvant induced arthritis QTL 4	3		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	15	55596089	91365858	Rat
631516	Gluco31	Glucose level QTL 31	7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	55596089	95018120	Rat
631655	Bp126	Blood pressure QTL 126	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	58156477	101769107	Rat
731177	Uae26	Urinary albumin excretion QTL 26	2.4	0.025	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	15	67588667	101769107	Rat
2300326	Plaw1	Placental weight QTL 1	15	0.005	placenta mass (VT:0004257)	placenta wet weight (CMO:0002088)	15	68327165	100062518	Rat
1331724	Bp223	Blood pressure QTL 223	3.53715		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	15	73690518	95018228	Rat
1641889	Colcr6	Colorectal carcinoma resistance QTL 6	2.9	0.0126	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	15	73690518	99794247	Rat
70182	BpQTLcluster12	Blood pressure QTL cluster 12	3.53		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	15	73690657	95018120	Rat
2317055	Aia10	Adjuvant induced arthritis QTL 10	3.41		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	15	75788062	101769107	Rat
1549844	Bss7	Bone structure and strength QTL 7	6.4		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	15	75788062	101769107	Rat
1581555	Eae19	Experimental allergic encephalomyelitis QTL 19	4.7		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	15	76306099	90088744	Rat
70155	Gcs1	Gastric cancer susceptibility QTL1	3.8		stomach morphology trait (VT:0000470)	stomach tumor susceptibility score (CMO:0002043)	15	76306099	101769107	Rat

Markers in Region

AU048285

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	80,539,149 - 80,539,272 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	87,903,276 - 87,903,396	NCBI	Rnor6.0
Rnor_5.0	15	91,398,499 - 91,398,619	UniSTS	Rnor5.0
RGSC_v3.4	15	87,766,820 - 87,766,940	UniSTS	RGSC3.4
Celera	15	79,672,634 - 79,672,754	UniSTS
Cytogenetic Map	15	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1		7		8				74		11
Low	2	24	22	13	11	13	4	4		35	30	11	4
Below cutoff		19	28	28		28	4	6					4

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014139	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001393854	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001393855	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093533	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093534	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039093535	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC088867	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ225797	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ226954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000065710 ⟹ ENSRNOP00000061269

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	80,498,647 - 80,542,350 (+)	Ensembl
Rnor_6.0 Ensembl	15	87,886,783 - 87,906,474 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000096527 ⟹ ENSRNOP00000090352

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	80,482,367 - 80,542,350 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000109076 ⟹ ENSRNOP00000092556

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	80,482,367 - 80,542,350 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000117967 ⟹ ENSRNOP00000081350

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	80,482,367 - 80,542,350 (+)	Ensembl

RefSeq Acc Id:

NM_001014139 ⟹ NP_001014161

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	80,498,647 - 80,542,348 (+)	NCBI
Rnor_6.0	15	87,862,832 - 87,906,472 (+)	NCBI
Rnor_5.0	15	91,357,889 - 91,401,695 (+)	NCBI
RGSC_v3.4	15	87,720,662 - 87,770,016 (+)	RGD
Celera	15	79,632,758 - 79,675,830 (+)	RGD

Sequence:

show sequence

CAGTGATCAGAAAGGTGGCCTTTTCATTTGTAAAATACGACACAGATTGAGCTGAGCCATTAGG
AGCTTATCAAGAATCTGTCTCGTGGAGCCTGTCCAGTGTCTCCTTGCATGGCCCAAGATGCTAT
CCCTGCCCGATCGTGTTTCCACTCCTGAGGTGCTCTGCCACATTTGGAACACTGATTTAAAGCT
TTGAAGGAGAGGTCATTTTAGGTTATACCTCCAGGGGCTCCCCACTTAGTCCACAGTCATCTAT
CGACAGTGAGCTGAGTACCTCAGAGTTGGAGGATGATTCTATATCCATGGGCTACAAGTTACAG
GACCTTACTGACGTCCAGATCATGGCTCGTCTGCAAGAAGAGAGCCTCAGGCAAGACTGTGCTT
CCACTTCAGGATCTGTGTCCAGGAACAGCTCCACCATTTCCCTGAGCTCAGGGAAAAAGGGGAC
GTGCAGTGATCAAGAGTACGATCGGTATAGCCTGGAGGACGAGGAAGAATTCGACCATTTGCCA
CCACCTCAGCCCCGACTTCCGAGGTGTTCACCCTTCCAAAGAGGCATCCCCCACTCACAGACTT
TCTCCAGCATTCGGGATTGCAGGAGGAGCCCCAGTTCCCAGTATTTCCCTTCAAATAATTTCCA
GCAGCCACAGTATTATTCACCTCAAGCCCAAACTCCAGATCAGCAACCAAATAGGACCAATGGA
GATAAACTACGAAGAAGTATGCCTAATCTGGCCCGGATGCCAAGCACCACTGCAGTCAGTAGCA
ACCTCAGCTCTCCCGTGACAGTGAGGAGCAGTCAGAGTTTTGACTCAAGCTTGCACGGAGCTGG
AAGTGGGGTTTCTCGGGTACCGTCCTGCATCCCGTCACCAGGACAGATTCAGCACAGAGTCCAC
AGCGTGGGGCATTTCCCAGTGCCCATCCGGCAGCCCCTGAAGGCCACAGCCTACGTCAGTCCGA
CTGTTCAGGGCAGCAGCAGCAGCATGCCTTTGTCCAATGGCACACAGTTATATTCCAACACCGG
CATCCCTACCCCAAACAAAGCTGCGGCTTCCGGGATTATGGGCCGCAGCGCCCTTCCGCGACCT
TCCTTGGCAATAAATGGGAGTAACCTGCCTCGAAGCAAGATTGCACAGCCTGTCAGGAGTTTCC
TGCAGCCCCCCAAGCCTCTATCTTCACTCAGCACACTGAGGGATGGAAATTGGAGAGACGGTTG
CTACTGATGCAGTTTTATGGACCCTTGTAGAATGGGAAGAATCGAAAATGAGGGTGTGTTACCT
AGCTGGCTGGGTAACCGTGGATGCTGGGATGCTCTCCCCTTCACCCTAACACGTGCGCACGGCA
TCGTTTTCAGTGGACCAATCACCAGAGACTAACGATCGCACTTACTCTCTGCCTGAAATACTGT
GGCAACCCCAAACCCATGGCCACGGTATTGTTACCTTAGATCTAGGAAGTTTTTGTAGAACTGC
TCTGTACCTGAATACTTTTTGAGAGAGATTGAGGCGTATCAATAATGCTTTGCCATATGGGGTT
TTTAAAGTACCTTTGTTCATTTTACCTACGTGTTCTAAACACCTTTCCATTACGTGTTCTGCAT
TTTAATACACTGCATATTTACAACTAGGTTCTATAACATGGTTTGGATTTTAATTTTTTTTTAT
AGTTTACAGGAATTTTATTTTTTTGTGCCTATTTCTTTTTATGCCTATGTGAACCACTATGGAA
CAACTTAAATTTTGTGCCATAAAAGTATTTTTGTGGTAAGGTACTATTTTTTTAGCTCTAGGGA
TTATATCAGCAAAAAGAAAAAAAAAAAACCACACCATACGATTTGAGACATAACTTTACGTTGA
ACGAGCACAATTTAGTCTAAAGCGTCGCAAAGGAGACAGCCAGACGGCAGAGTTAAGCGGTCTT
GTCTTTTTTCATTGTTAATTTATTGTCTTACATGAGTTTCATATTTATGATGGCATCACAGACC
CGTTGCACTTAAGACCCGCAATGTTTGCTACTCAACCACAATTGATTTTCAATACTTTATTACA
AAGGACGAAACTGTAATGTTTTATTAACAATGCTTCTGGAAACGAACGCATTTTAAAGCAAATA
AATCTTTTTGATAGACCTTTTCCAAAAAAAAAAAAAAAAAAAAAAAAAGG

hide sequence

RefSeq Acc Id:

XM_039093533 ⟹ XP_038949461

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	80,482,818 - 80,542,461 (+)	NCBI

RefSeq Acc Id:

XM_039093534 ⟹ XP_038949462

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	80,482,818 - 80,542,461 (+)	NCBI

RefSeq Acc Id:

XM_039093535 ⟹ XP_038949463

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	80,491,080 - 80,542,461 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014161	(Get FASTA)	NCBI Sequence Viewer
	NP_001380783	(Get FASTA)	NCBI Sequence Viewer
	NP_001380784	(Get FASTA)	NCBI Sequence Viewer
	XP_038949461	(Get FASTA)	NCBI Sequence Viewer
	XP_038949462	(Get FASTA)	NCBI Sequence Viewer
	XP_038949463	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH88867	(Get FASTA)	NCBI Sequence Viewer
	EDM02464	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001014161 ⟸ NM_001014139

- UniProtKB:

Q5HZW0 (UniProtKB/TrEMBL), D4A5Y9 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGYKLQDLTDVQIMARLQEESLRQDCASTSGSVSRNSSTISLSSGKKGTCSDQEYDRYSLEDEE
EFDHLPPPQPRLPRCSPFQRGIPHSQTFSSIRDCRRSPSSQYFPSNNFQQPQYYSPQAQTPDQQ
PNRTNGDKLRRSMPNLARMPSTTAVSSNLSSPVTVRSSQSFDSSLHGAGSGVSRVPSCIPSPGQ
IQHRVHSVGHFPVPIRQPLKATAYVSPTVQGSSSSMPLSNGTQLYSNTGIPTPNKAAASGIMGR
SALPRPSLAINGSNLPRSKIAQPVRSFLQPPKPLSSLSTLRDGNWRDGCY

hide sequence

RefSeq Acc Id:

ENSRNOP00000061269 ⟸ ENSRNOT00000065710

RefSeq Acc Id:	XP_038949461 ⟸ XM_039093533
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038949462 ⟸ XM_039093534
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038949463 ⟸ XM_039093535
- Peptide Label:	isoform X3
- UniProtKB:	D4A5Y9 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000090352 ⟸ ENSRNOT00000096527

RefSeq Acc Id:

ENSRNOP00000081350 ⟸ ENSRNOT00000117967

RefSeq Acc Id:

ENSRNOP00000092556 ⟸ ENSRNOT00000109076

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-D4A5Y9-F1-model_v2	AlphaFold	D4A5Y9	1-293	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308626	AgrOrtholog
BioCyc Gene	G2FUF-12666	BioCyc
Ensembl Genes	ENSRNOG00000024125	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000061269	ENTREZGENE
	ENSRNOP00000061269.4	UniProtKB/TrEMBL
	ENSRNOP00000081350	ENTREZGENE
	ENSRNOP00000081350.1	UniProtKB/TrEMBL
	ENSRNOP00000090352	ENTREZGENE
	ENSRNOP00000090352.1	UniProtKB/TrEMBL
	ENSRNOP00000092556.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000065710	ENTREZGENE
	ENSRNOT00000065710.4	UniProtKB/TrEMBL
	ENSRNOT00000096527	ENTREZGENE
	ENSRNOT00000096527.1	UniProtKB/TrEMBL
	ENSRNOT00000109076.1	UniProtKB/TrEMBL
	ENSRNOT00000117967	ENTREZGENE
	ENSRNOT00000117967.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7320965	IMAGE-MGC_LOAD
InterPro	Slain	UniProtKB/TrEMBL
KEGG Report	rno:361087	UniProtKB/TrEMBL
MGC_CLONE	MGC:105641	IMAGE-MGC_LOAD
NCBI Gene	361087	ENTREZGENE
PANTHER	PTHR22406	UniProtKB/TrEMBL
	SLAIN MOTIF-CONTAINING PROTEIN 1	UniProtKB/TrEMBL
Pfam	SLAIN	UniProtKB/TrEMBL
PhenoGen	Slain1	PhenoGen
UniProt	A0A8I5ZRS3	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6ABM8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AHR5_RAT	UniProtKB/TrEMBL
	D4A5Y9	ENTREZGENE
	Q5HZW0	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	D4A5Y9	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2012-10-10	Slain1	SLAIN motif family, member 1	RGD1308626	similar to 9630044O09Rik protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1308626	similar to 9630044O09Rik protein	RGD1308626_predicted	similar to 9630044O09Rik protein (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1308626_predicted	similar to 9630044O09Rik protein (predicted)	LOC361087_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC361087_predicted	similar to 9630044O09Rik protein (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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