Dennd4c (DENN domain containing 4C) - Rat Genome Database

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Pathways
Gene: Dennd4c (DENN domain containing 4C) Rattus norvegicus
Analyze
Symbol: Dennd4c
Name: DENN domain containing 4C
RGD ID: 1308489
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to insulin stimulus and protein localization to plasma membrane. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and insulin-responsive compartment. Predicted to be part of retromer complex. Orthologous to human DENND4C (DENN domain containing 4C); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: DENN domain-containing protein 4C; DENN/MADD domain containing 4C; LOC102555797; LOC313340; RGD1308489; similar to hypothetical protein; uncharacterized LOC102555797
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25101,272,298 - 101,369,529 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5101,272,005 - 101,368,118 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05105,100,081 - 105,195,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,114,433 - 105,193,988 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05109,085,833 - 109,182,502 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45106,090,415 - 106,162,420 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15106,090,717 - 106,167,026 (+)NCBI
Celera5101,714,237 - 101,809,916 (-)NCBICelera
Cytogenetic Map5q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Signal transduction meets vesicle traffic: the software and hardware of GLUT4 translocation. Klip A, etal., Am J Physiol Cell Physiol. 2014 May 15;306(10):C879-86. doi: 10.1152/ajpcell.00069.2014. Epub 2014 Mar 5.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:20937701   PMID:21454697   PMID:22472443   PMID:33090893  


Genomics

Comparative Map Data
Dennd4c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.25101,272,298 - 101,369,529 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5101,272,005 - 101,368,118 (+)EnsemblmRatBN7.2 Ensembl
Rnor_6.05105,100,081 - 105,195,634 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,114,433 - 105,193,988 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05109,085,833 - 109,182,502 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45106,090,415 - 106,162,420 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15106,090,717 - 106,167,026 (+)NCBI
Celera5101,714,237 - 101,809,916 (-)NCBICelera
Cytogenetic Map5q32NCBI
DENND4C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38919,230,513 - 19,374,281 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl919,230,435 - 19,374,281 (+)EnsemblGRCh38hg38GRCh38
GRCh37919,230,511 - 19,374,279 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36919,280,749 - 19,364,139 (+)NCBINCBI36Build 36hg18NCBI36
Build 34919,288,065 - 19,362,856NCBI
Celera919,216,854 - 19,300,236 (+)NCBICelera
Cytogenetic Map9p22.1NCBI
HuRef919,192,829 - 19,335,696 (+)NCBIHuRef
CHM1_1919,230,600 - 19,373,937 (+)NCBICHM1_1
T2T-CHM13v2.0919,243,303 - 19,387,084 (+)NCBIT2T-CHM13v2.0
Dennd4c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39486,666,761 - 86,768,841 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl486,666,792 - 86,768,840 (+)EnsemblGRCm39 Ensembl
GRCm38486,748,518 - 86,850,603 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl486,748,555 - 86,850,603 (+)EnsemblGRCm38mm10GRCm38
MGSCv37486,394,459 - 86,476,071 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36486,219,786 - 86,321,834 (+)NCBIMGSCv36mm8
Celera485,265,548 - 85,350,171 (+)NCBICelera
Cytogenetic Map4C4NCBI
cM Map440.69NCBI
Dennd4c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543421,639,986 - 21,740,842 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543421,640,068 - 21,740,842 (+)NCBIChiLan1.0ChiLan1.0
DENND4C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan19105,178,690 - 105,315,282 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0919,046,857 - 19,183,364 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1919,537,938 - 19,672,299 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl919,537,997 - 19,672,299 (+)Ensemblpanpan1.1panPan2
DENND4C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11139,035,241 - 39,161,135 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1139,072,944 - 39,159,611 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1137,693,992 - 37,818,852 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01139,968,568 - 40,094,556 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1139,968,663 - 40,093,014 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11138,661,590 - 38,786,923 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01138,456,479 - 38,584,445 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01139,093,527 - 39,218,421 (+)NCBIUU_Cfam_GSD_1.0
Dennd4c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947153,479,598 - 153,581,391 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366521,149,099 - 1,250,921 (+)EnsemblSpeTri2.0
SpeTri2.0NW_0049366521,149,106 - 1,250,571 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DENND4C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1203,449,835 - 203,601,292 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11203,449,832 - 203,601,298 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,100,329 - 227,251,158 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DENND4C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11260,359,979 - 60,499,631 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1260,361,914 - 60,499,713 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603848,473,266 - 48,616,996 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dennd4c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473623,233,444 - 23,326,780 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473623,206,686 - 23,328,391 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dennd4c
315 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:106
Count of miRNA genes:82
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000058429
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)558829236128034027Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
2316957Pur21Proteinuria QTL 216.2urine protein amount (VT:0005160)urine protein level (CMO:0000591)559793528113558156Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)564719390109719390Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)566174080124160948Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)568984307104251008Rat
61380Edpm5Estrogen-dependent pituitary mass QTL 54.50.92pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)568984307104251008Rat
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)568984307104251008Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)568984307104251008Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)579584860124584860Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)579584860124584860Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)579584860124584860Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584132602129132602Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)590067849128034027Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)590067849128034027Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)599016066119085810Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)599485997103690167Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)599753548113061097Rat

Markers in Region
D5Rat24  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,278,414 - 101,278,701 (+)MAPPERmRatBN7.2
Rnor_6.05105,106,199 - 105,106,485NCBIRnor6.0
Rnor_5.05109,093,330 - 109,093,616UniSTSRnor5.0
Celera5101,803,513 - 101,803,799UniSTS
RH 3.4 Map5737.3UniSTS
RH 3.4 Map5737.3RGD
RH 2.0 Map5649.9RGD
SHRSP x BN Map558.1899RGD
Cytogenetic Map5q32UniSTS
RH138658  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,369,075 - 101,369,271 (+)MAPPERmRatBN7.2
Rnor_6.05105,207,206 - 105,207,401NCBIRnor6.0
Rnor_6.05105,195,181 - 105,195,376NCBIRnor6.0
Rnor_5.05109,194,074 - 109,194,269UniSTSRnor5.0
Rnor_5.05109,182,049 - 109,182,244UniSTSRnor5.0
RGSC_v3.45106,162,972 - 106,163,167UniSTSRGSC3.4
Celera5101,714,495 - 101,714,690UniSTS
RH 3.4 Map5737.5UniSTS
Cytogenetic Map5q32UniSTS
RH124387  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,369,255 - 101,369,485 (+)MAPPERmRatBN7.2
Rnor_6.05105,207,386 - 105,207,615NCBIRnor6.0
Rnor_6.05105,195,361 - 105,195,590NCBIRnor6.0
Rnor_5.05109,182,229 - 109,182,458UniSTSRnor5.0
Rnor_5.05109,194,254 - 109,194,483UniSTSRnor5.0
RGSC_v3.45106,163,152 - 106,163,381UniSTSRGSC3.4
Celera5101,714,281 - 101,714,510UniSTS
Cytogenetic Map5q32UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 34 28 12 18 12 8 8 68 34 38 11 8
Low 1 9 29 29 1 29 3 6 1 3
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000058429   ⟹   ENSRNOP00000055230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5105,114,433 - 105,177,988 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082596   ⟹   ENSRNOP00000071348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5101,272,005 - 101,368,118 (+)Ensembl
Rnor_6.0 Ensembl5105,114,433 - 105,193,988 (+)Ensembl
RefSeq Acc Id: XM_039111087   ⟹   XP_038967015
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,272,299 - 101,369,529 (+)NCBI
RefSeq Acc Id: XM_039111088   ⟹   XP_038967016
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,272,299 - 101,366,928 (+)NCBI
RefSeq Acc Id: XM_039111089   ⟹   XP_038967017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,272,299 - 101,369,529 (+)NCBI
RefSeq Acc Id: XM_039111090   ⟹   XP_038967018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,296,295 - 101,369,529 (+)NCBI
RefSeq Acc Id: XM_039111091   ⟹   XP_038967019
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,329,451 - 101,369,529 (+)NCBI
RefSeq Acc Id: XM_039111092   ⟹   XP_038967020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.25101,272,298 - 101,334,837 (+)NCBI
RefSeq Acc Id: ENSRNOP00000071348   ⟸   ENSRNOT00000082596
RefSeq Acc Id: ENSRNOP00000055230   ⟸   ENSRNOT00000058429
RefSeq Acc Id: XP_038967020   ⟸   XM_039111092
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038967015   ⟸   XM_039111087
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K089 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967017   ⟸   XM_039111089
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038967016   ⟸   XM_039111088
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038967018   ⟸   XM_039111090
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038967019   ⟸   XM_039111091
- Peptide Label: isoform X5
- UniProtKB: A6KRC4 (UniProtKB/TrEMBL)
Protein Domains
MABP   uDENN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K089-F1-model_v2 AlphaFold A0A0G2K089 1-1901 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308489 AgrOrtholog
BioCyc Gene G2FUF-40839 BioCyc
Ensembl Genes ENSRNOG00000008036 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000071348 ENTREZGENE
  ENSRNOP00000071348.2 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082596 ENTREZGENE
  ENSRNOT00000082596.2 UniProtKB/TrEMBL
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  2.100.10.50 UniProtKB/TrEMBL
  3.40.50.11500 UniProtKB/TrEMBL
InterPro dDENN_dom UniProtKB/TrEMBL
  DENN_C UniProtKB/TrEMBL
  DENN_dom UniProtKB/TrEMBL
  MABP UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  Tripartite_DENN UniProtKB/TrEMBL
  uDENN_dom UniProtKB/TrEMBL
NCBI Gene 313340 ENTREZGENE
PANTHER DENN DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  DENN DOMAIN-CONTAINING PROTEIN 4C UniProtKB/TrEMBL
Pfam dDENN UniProtKB/TrEMBL
  DENN UniProtKB/TrEMBL
  uDENN UniProtKB/TrEMBL
PhenoGen Dennd4c PhenoGen
PROSITE DENN UniProtKB/TrEMBL
  MABP UniProtKB/TrEMBL
SMART dDENN UniProtKB/TrEMBL
  DENN UniProtKB/TrEMBL
  uDENN UniProtKB/TrEMBL
UniProt A0A0G2K089 ENTREZGENE, UniProtKB/TrEMBL
  A6KRC4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Dennd4c  DENN domain containing 4C  LOC102555797  uncharacterized LOC102555797  Data Merged 737654 PROVISIONAL
2016-02-17 Dennd4c  DENN domain containing 4C  Dennd4c  DENN/MADD domain containing 4C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-29 Dennd4c  DENN/MADD domain containing 4C  RGD1308489  similar to hypothetical protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102555797  uncharacterized LOC102555797      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1308489  similar to hypothetical protein   RGD1308489_predicted  similar to hypothetical protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308489_predicted  similar to hypothetical protein (predicted)  LOC313340_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313340_predicted  similar to hypothetical protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL