Dennd4c (DENN domain containing 4C) - Rat Genome Database

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Pathways
Gene: Dennd4c (DENN domain containing 4C) Rattus norvegicus
Analyze
Symbol: Dennd4c
Name: DENN domain containing 4C
RGD ID: 1308489
Description: Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to be involved in cellular response to insulin stimulus; protein localization to plasma membrane; and regulation of Rab protein signal transduction. Predicted to be located in several cellular components, including Golgi apparatus; cytosol; and insulin-responsive compartment. Predicted to be part of retromer complex. Predicted to be active in cytoplasmic vesicle. Orthologous to human DENND4C (DENN domain containing 4C); PARTICIPATES IN insulin responsive facilitative sugar transporter mediated glucose transport pathway; Rab family mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; amphetamine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DENN domain-containing protein 4C; DENN/MADD domain containing 4C; LOC102555797; LOC313340; RGD1308489; similar to hypothetical protein; uncharacterized LOC102555797
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85106,316,942 - 106,421,484 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5106,318,281 - 106,415,489 (+)EnsemblGRCr8
mRatBN7.25101,272,298 - 101,369,529 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5101,272,005 - 101,368,118 (+)EnsemblmRatBN7.2
Rnor_6.05105,100,081 - 105,195,634 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,114,433 - 105,193,988 (+)Ensemblrn6Rnor6.0
Rnor_5.05109,085,833 - 109,182,502 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45106,090,415 - 106,162,420 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5101,714,237 - 101,809,916 (-)NCBICelera
RGSC_v3.15106,090,717 - 106,167,026 (+)NCBI
Cytogenetic Map5q32NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Signal transduction meets vesicle traffic: the software and hardware of GLUT4 translocation. Klip A, etal., Am J Physiol Cell Physiol. 2014 May 15;306(10):C879-86. doi: 10.1152/ajpcell.00069.2014. Epub 2014 Mar 5.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:20937701   PMID:21454697   PMID:22472443   PMID:33090893  


Genomics

Comparative Map Data
Dennd4c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85106,316,942 - 106,421,484 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl5106,318,281 - 106,415,489 (+)EnsemblGRCr8
mRatBN7.25101,272,298 - 101,369,529 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5101,272,005 - 101,368,118 (+)EnsemblmRatBN7.2
Rnor_6.05105,100,081 - 105,195,634 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5105,114,433 - 105,193,988 (+)Ensemblrn6Rnor6.0
Rnor_5.05109,085,833 - 109,182,502 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.45106,090,415 - 106,162,420 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera5101,714,237 - 101,809,916 (-)NCBICelera
RGSC_v3.15106,090,717 - 106,167,026 (+)NCBI
Cytogenetic Map5q32NCBI
DENND4C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38919,230,513 - 19,374,281 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl919,230,435 - 19,374,281 (+)Ensemblhg38GRCh38
GRCh37919,230,511 - 19,374,279 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36919,280,749 - 19,364,139 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34919,288,065 - 19,362,856NCBI
Celera919,216,854 - 19,300,236 (+)NCBICelera
Cytogenetic Map9p22.1NCBI
HuRef919,192,829 - 19,335,696 (+)NCBIHuRef
CHM1_1919,230,600 - 19,373,937 (+)NCBICHM1_1
T2T-CHM13v2.0919,243,303 - 19,387,084 (+)NCBIT2T-CHM13v2.0
Dennd4c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39486,666,761 - 86,768,841 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl486,666,792 - 86,768,840 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38486,748,518 - 86,850,603 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl486,748,555 - 86,850,603 (+)Ensemblmm10GRCm38
MGSCv37486,394,459 - 86,476,071 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36486,219,786 - 86,321,834 (+)NCBIMGSCv36mm8
Celera485,265,548 - 85,350,171 (+)NCBICelera
Cytogenetic Map4C4NCBI
cM Map440.69NCBI
Dennd4c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543421,639,986 - 21,740,842 (+)Ensembl
ChiLan1.0NW_00495543421,640,068 - 21,740,842 (+)NCBIChiLan1.0ChiLan1.0
DENND4C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v211105,172,746 - 105,309,405 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan19105,178,690 - 105,315,282 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0919,046,857 - 19,183,364 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1919,537,938 - 19,672,299 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl919,537,997 - 19,672,299 (+)EnsemblpanPan2panpan1.1
DENND4C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11139,035,241 - 39,161,135 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1139,072,944 - 39,159,611 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1137,693,992 - 37,818,852 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01139,968,568 - 40,094,556 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1139,968,663 - 40,093,014 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11138,661,590 - 38,786,923 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01138,456,479 - 38,584,445 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01139,093,527 - 39,218,421 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dennd4c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947153,479,598 - 153,581,391 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366521,149,099 - 1,250,921 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049366521,149,106 - 1,250,571 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DENND4C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1203,449,835 - 203,601,292 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11203,449,832 - 203,601,298 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21227,100,329 - 227,251,158 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DENND4C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11260,359,979 - 60,499,631 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1260,361,914 - 60,499,713 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366603848,473,266 - 48,616,996 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dennd4c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473623,233,444 - 23,326,780 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473623,206,686 - 23,328,391 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Dennd4c
701 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:106
Count of miRNA genes:82
Interacting mature miRNAs:89
Transcripts:ENSRNOT00000058429
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357396Bw44Body weight QTL 444.19body mass (VT:0001259)body weight (CMO:0000012)573779642118779642Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)5102105698152749382Rat
2303586Gluco52Glucose level QTL 522blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)5100826632145826632Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
1298070Scl18Serum cholesterol level QTL 183.7blood LDL cholesterol amount (VT:0000181)calculated plasma low density lipoprotein cholesterol level (CMO:0001245)584630798129630798Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)599905133172190305Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
2302381Bw84Body weight QTL 844.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
1357402Bw46Body weight QTL 464.47body mass (VT:0001259)body mass index (BMI) (CMO:0000105)573779642118779642Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)565089051166764498Rat
1598859Cm66Cardiac mass QTL 662heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)584630798129630798Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1582212Livw2Liver weight QTL 23.50.0004liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)5104018576124314782Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)592583776137583776Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)598972960143972960Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)592583776137583776Rat
2303618Vencon1Ventilatory control QTL 13.8respiration trait (VT:0001943)oxygen consumption (CMO:0002169)5100826632145826632Rat
7394708Emca11Estrogen-induced mammary cancer QTL 11mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)573176602118176602Rat
1598846Bp293Blood pressure QTL 2933.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)584630798129630798Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)594034903139034903Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)569474415114474415Rat
1358909Kidm25Kidney mass QTL 251.87kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)595062526133270832Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)564589016109589016Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)574335621156302135Rat
1600362Mcs19Mammary carcinoma susceptibility QTL 192.5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)582032155127032155Rat
1298086Bp156Blood pressure QTL 156arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)589369373134369373Rat
2290005Mcs24Mammary carcinoma susceptibility QTL 24mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)569835120114835120Rat
2306971Anxrr21Anxiety related response QTL 219.47fear/anxiety-related behavior trait (VT:1000241)number of entries into a discrete space in an experimental apparatus (CMO:0000960)570969494136328156Rat
1358895Bp254Blood pressure QTL 2543.60.0003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)597492524133270832Rat
2312671Scl64Serum cholesterol level QTL 640.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)573779642118779642Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)592881678137881678Rat
1358889Bp261Blood pressure QTL 2612.86arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)595062526133270832Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)5104262817153890625Rat

Markers in Region
D5Rat24  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,278,414 - 101,278,701 (+)MAPPERmRatBN7.2
Rnor_6.05105,106,199 - 105,106,485NCBIRnor6.0
Rnor_5.05109,093,330 - 109,093,616UniSTSRnor5.0
Celera5101,803,513 - 101,803,799UniSTS
RH 3.4 Map5737.3RGD
RH 3.4 Map5737.3UniSTS
RH 2.0 Map5649.9RGD
SHRSP x BN Map558.1899RGD
Cytogenetic Map5q32UniSTS
RH138658  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,369,075 - 101,369,271 (+)MAPPERmRatBN7.2
Rnor_6.05105,207,206 - 105,207,401NCBIRnor6.0
Rnor_6.05105,195,181 - 105,195,376NCBIRnor6.0
Rnor_5.05109,194,074 - 109,194,269UniSTSRnor5.0
Rnor_5.05109,182,049 - 109,182,244UniSTSRnor5.0
RGSC_v3.45106,162,972 - 106,163,167UniSTSRGSC3.4
Celera5101,714,495 - 101,714,690UniSTS
RH 3.4 Map5737.5UniSTS
Cytogenetic Map5q32UniSTS
RH124387  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25101,369,255 - 101,369,485 (+)MAPPERmRatBN7.2
Rnor_6.05105,207,386 - 105,207,615NCBIRnor6.0
Rnor_6.05105,195,361 - 105,195,590NCBIRnor6.0
Rnor_5.05109,182,229 - 109,182,458UniSTSRnor5.0
Rnor_5.05109,194,254 - 109,194,483UniSTSRnor5.0
RGSC_v3.45106,163,152 - 106,163,381UniSTSRGSC3.4
Celera5101,714,281 - 101,714,510UniSTS
Cytogenetic Map5q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000058429   ⟹   ENSRNOP00000055230
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl5105,114,433 - 105,177,988 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000082596   ⟹   ENSRNOP00000071348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5106,318,283 - 106,414,071 (+)Ensembl
mRatBN7.2 Ensembl5101,272,005 - 101,368,118 (+)Ensembl
Rnor_6.0 Ensembl5105,114,433 - 105,193,988 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000159225   ⟹   ENSRNOP00000102197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl5106,318,281 - 106,415,489 (+)Ensembl
RefSeq Acc Id: NM_001427785   ⟹   NP_001414714
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85106,318,371 - 106,415,493 (+)NCBI
RefSeq Acc Id: XM_039111089   ⟹   XP_038967017
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85106,316,942 - 106,421,484 (+)NCBI
mRatBN7.25101,272,299 - 101,369,529 (+)NCBI
RefSeq Acc Id: XM_039111090   ⟹   XP_038967018
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85106,342,269 - 106,421,484 (+)NCBI
mRatBN7.25101,296,295 - 101,369,529 (+)NCBI
RefSeq Acc Id: XM_039111092   ⟹   XP_038967020
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85106,316,942 - 106,380,803 (+)NCBI
mRatBN7.25101,272,298 - 101,334,837 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001414714 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967017 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967018 (Get FASTA)   NCBI Sequence Viewer  
  XP_038967020 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000071348
  ENSRNOP00000071348.2
  ENSRNOP00000102197
Ensembl Acc Id: ENSRNOP00000071348   ⟸   ENSRNOT00000082596
Ensembl Acc Id: ENSRNOP00000055230   ⟸   ENSRNOT00000058429
RefSeq Acc Id: XP_038967020   ⟸   XM_039111092
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038967017   ⟸   XM_039111089
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038967018   ⟸   XM_039111090
- Peptide Label: isoform X2
RefSeq Acc Id: NP_001414714   ⟸   NM_001427785
- UniProtKB: A0A0G2K089 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000102197   ⟸   ENSRNOT00000159225
Protein Domains
MABP   uDENN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K089-F1-model_v2 AlphaFold A0A0G2K089 1-1901 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308489 AgrOrtholog
BioCyc Gene G2FUF-40839 BioCyc
Ensembl Genes ENSRNOG00000008036 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082596 ENTREZGENE
  ENSRNOT00000082596.2 UniProtKB/TrEMBL
  ENSRNOT00000159225 ENTREZGENE
Gene3D-CATH 1.25.40.10 UniProtKB/TrEMBL
  2.100.10.50 UniProtKB/TrEMBL
  3.40.50.11500 UniProtKB/TrEMBL
InterPro dDENN_dom UniProtKB/TrEMBL
  DENN_C UniProtKB/TrEMBL
  DENN_dom UniProtKB/TrEMBL
  DENN_Domain_GEFs UniProtKB/TrEMBL
  MABP UniProtKB/TrEMBL
  TPR-like_helical_dom_sf UniProtKB/TrEMBL
  Tripartite_DENN UniProtKB/TrEMBL
  uDENN_dom UniProtKB/TrEMBL
NCBI Gene 313340 ENTREZGENE
PANTHER DENN DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  DENN DOMAIN-CONTAINING PROTEIN 4C UniProtKB/TrEMBL
Pfam dDENN UniProtKB/TrEMBL
  DENN UniProtKB/TrEMBL
  uDENN UniProtKB/TrEMBL
PhenoGen Dennd4c PhenoGen
PROSITE DENN UniProtKB/TrEMBL
  MABP UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008036 RatGTEx
SMART dDENN UniProtKB/TrEMBL
  DENN UniProtKB/TrEMBL
  uDENN UniProtKB/TrEMBL
UniProt A0A0G2K089 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Dennd4c  DENN domain containing 4C  LOC102555797  uncharacterized LOC102555797  Data merged from RGD:7556518 737654 PROVISIONAL
2016-02-17 Dennd4c  DENN domain containing 4C  Dennd4c  DENN/MADD domain containing 4C  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-07-29 Dennd4c  DENN/MADD domain containing 4C  RGD1308489  similar to hypothetical protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102555797  uncharacterized LOC102555797      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1308489  similar to hypothetical protein   RGD1308489_predicted  similar to hypothetical protein (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-20 RGD1308489_predicted  similar to hypothetical protein (predicted)  LOC313340_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC313340_predicted  similar to hypothetical protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL